Enabling parallel computing in CRASH

We present the new parallel version (pCRASH2) of the cosmological radiative transfer code CRASH2 for distributed memory supercomputing facilities. The code is based on a static domain decomposition strategy inspired by geometric dilution of photons in the optical thin case that ensures a favourable performance speed-up with increasing number of computational cores. Linear speed-up is ensured as long as the number of radiation sources is equal to the number of computational cores or larger. The propagation of rays is segmented and rays are only propagated through one sub-domain per time step to guarantee an optimal balance between communication and computation. We have extensively checked pCRASH2 with a standardised set of test cases to validate the parallelisation scheme. The parallel version of CRASH2 can easily handle the propagation of radiation from a large number of sources and is ready for the extension of the ionisation network to species other than hydrogen and helium.Comment: Accepted by Monthly Notices of the Royal Astronomical Society. 18 pages, 20 figure

Isolated complete avulsion of the gallbladder (near traumatic cholecystectomy): a case report and review of the literature

<p>Abstract</p> <p>Introduction</p> <p>Injury of the gallbladder after blunt abdominal trauma is an unusual finding; the reported incidence is less than 2%. Three groups of injuries are described: simple contusion, laceration, and avulsion, the last of which can be partial, complete, or total traumatic cholecystectomy.</p> <p>Case presentation</p> <p>A case of isolated complete avulsion of the gallbladder (near traumatic cholecystectomy) from its hepatic bed in a 46-year-old Caucasian man without any other sign of injury is presented. The avulsion was due to blunt abdominal trauma after a car accident. The rarity of this injury and the stable condition of our patient at the initial presentation warrant a description. The diagnosis was made incidentally after a computed tomography scan, and our patient was treated successfully with ligation of the cystic duct and artery, removal of the gallbladder, coagulation of the bleeding points, and placement of a drain.</p> <p>Conclusions</p> <p>Early diagnosis of such injuries is quite difficult because abdominal signs are poor, non-specific, or even absent. Therefore, a computed tomography scan should be performed when the mechanism of injury is indicated.</p

Kinematics of the Southern Rhodope Core Complex (North Greece)

The Southern Rhodope Core Complex is a wide metamorphic dome exhumed in the northern Aegean as a result of large-scale extension from mid-Eocene to mid-Miocene times. Its roughly triangular shape is bordered on the SW by the Jurassic and Cretaceous metamorphic units of the Serbo-Macedonian in the Chalkidiki peninsula and on the N by the eclogite bearing gneisses of the Sideroneron massif. The main foliation of metamorphic rocks is flat lying up to 100 km core complex width. Most rocks display a stretching lineation trending NEâ SW. The Kerdylion detachment zone located at the SW controlled the exhumation of the core complex from middle Eocene to mid-Oligocene. From late Oligocene to mid-Miocene exhumation is located inside the dome and is accompanied by the emplacement of the synkinematic plutons of Vrondou and Symvolon. Since late Miocene times, extensional basin sediments are deposited on top of the exhumed metamorphic and plutonic rocks and controlled by steep normal faults and flat-ramp-type structures. Evidence from Thassos Island is used to illustrate the sequence of deformation from stacking by thrusting of the metamorphic pile to ductile extension and finally to development of extensional Plio-Pleistocene sedimentary basin. Paleomagnetic data indicate that the core complex exhumation is controlled by a 30� dextral rotation of the Chalkidiki block. Extensional displacements are restored using a pole of rotation deduced from the curvature of stretching lineation trends at core complex scale. It is argued that the Rhodope Core Complex has recorded at least 120 km of extension in the North Aegean, since the last 40 My

Knowledge and behaviors regarding salt intake in Mozambique

Background/objectives: Health education and regulatory measures may contribute to lower population salt intake. Therefore, we aimed to describe knowledge and behaviors related to salt intake in Mozambique. Subjects/methods: A cross-sectional evaluation of a representative sample of the population aged 15–64 years (n = 3116) was conducted in 2014/2015, following the Stepwise Approach to Chronic Disease Risk Factor Surveillance, including a 12-question module for evaluation of dietary salt. Results: Three dimensions were identified in the questionnaire, named “self-reported salt intake”, “knowledge of health effects of salt intake”, and “behaviors for control of salt intake”. A total of 7.4% of the participants perceived that they consumed too much/far too much salt and 25.9% reported adding salt/salty seasoning often/always to prepared foods. The proportion considering that it was not important to decrease the salt contents of their diet was 8%, and 16.9% were not aware that high salt intake could be deleterious for health. Prevalences of lack of behaviors for reducing salt intake ranged from 74.9% for not limiting consumption of processed foods, to 95% for not buying low salt alternatives. There were few differences according to socio-demographic variables, but awareness of hypertension was, in general, associated with better knowledge and less frequent behaviors likely to contribute to a high salt intake. Conclusions: Most Mozambicans were aware that high salt intake can cause health problems, but the self-reported salt intake and behaviors for its control show an ample margin for improvement. This study provides evidence to guide population level salt-reducing policies

Acid production by bifidobacteria and yoghurt bacteria during fermentation and storage of milk

Three species of bifidobacteria, namely Bifidobacterium bifidum, Bifidobacterium longum and Bifidobacterium adolescentis were used in pure culture and in combination with yoghurt bacteria (B3 and SBI cultures) for the production of fermented milks. The number of bacteria during fermentation and the level of acid produced during fermentation and storage were assessed using Rogosa&apos;s modified selective agar and high performance liquid chromatography (HPLC). It was found that during fermentation all bifidobacteria exhibited growth uncoupled from acid production. Two of the species examined produced only low levels of acids when grown individually and only B. adolescentis produced appreciable amounts. In mixed cultures, the level of acid was a reflection of the combination of yoghurt culture and species of Bifidobacterium, and this, observation suggests that there is a degree of influence between the cultures. During storage, the acid concentration remained quite stable in most samples. The prevention of post- production acidification that normally occurs during storage of yoghurt can be attributed to the presence of bifidobacteria, end it could be that acetic acid has a marginally inhibitory effect on the Lactobacillus and Streptococcus spp

Vinasse rate, time of application and compaction effect on soil properties and durum wheat crop

The results of an experiment studying the effects of vinasse (an alcohol industry waste) recycling in agriculture are reported in this work. Vinasse was applied in a durum wheat crop by a trailed vinasse sprayer system compacting about 10% of the field. The experiment was carried out in Central Greece, on two soils (a clay and a silty clay loam) with three levels of vinasse rate (one fully covering N requirements of the crop, one covering half the N requirements, the rest covered by chemical fertilizers and a control without vinasse and use only of chemical fertilizers) and three times of application (Summer, Autumn before ploughing and Autumn before drilling). The middle strip of the plots was compacted by three passes of the tractor-trailed vinasse sprayer producing the compacted treatment. During the experiment, the physical and chemical properties of the soil were measured as well as the plant growth and yield. It was found that the compacted plots had higher dry bulk density and soil strength, while vinasse rate and time of application effects were not significant. An increase in N, exchangeable Na + , K + and available Mn was caused by vinasse application. Compaction had a significant effect on plant growth, while vinasse rate and time of application effects were not significant. Yields were affected by weather conditions. In the compacted plots, the yields were generally lower but in the wet years they were also significant. Yields were higher at higher vinasse rates and lower for the application before ploughing in the autumn, indicating an adverse effect of that treatment. The combined analysis of the yields for the four years showed a significant adverse effect of compaction in the clay soil, while in the silty clay loam the effect was not significant. Vinasse application significantly increased yields, while an adverse effect was observed for the applications before ploughing. The work proved the beneficial effects of vinasse recycling as a substitute for chemical fertilizers and the feasibility of using of a spraying system, which compacts only the 10% of the field, to reduce any adverse economic effect of soil compaction on the crop. © 1999 Silsoe Research Institute

Enhanced Wellbeing of Adults with Type 2 Diabetes following Multi-Vitamin and Mineral Supplementation for Three Months in a Randomised, Double-blind, Cross-over Pilot Study

Objective: To investigate the effects of a daily multinutrient supplement on plasma indicators of glycemic and lipemic control and psychological wellbeing in type 2 diabetic patients. Design: Double-blind, randomised, cross-over pilot intervention study. Subjects: Twenty-nine subjects (15 males and 14 females) with non-insulin-dependent type 2 diabetes. Intervention: Either a multinutrient supplement or placebo were provided daily during two intervention periods of 3 months separated by a 4 week washout.Results: There were no significant changes of multinutrient treatment compared with placebo in HbA1c, fasting or postprandial plasma glucose and insulin concentrations and fasting plasma lipid concentrations. Using a validated wellbeing questionnaire (W-BQ 22) designed for diabetic subjects, the multinutrient supplement resulted in improvements in the secondary outcome of wellbeing of the volunteers in terms of anxiety (p = 0.020), vitality (p = 0.013) and general wellbeing (p = 0.021), relative to placebo.Conclusions: Findings from this pilot study suggest that a multinutrient supplement may enhance the wellbeing of diabetic patients, even in the absence of a significant improvement in clinical parameters. If substantiated in a full clinical study the results would have important implications for the prevention of late complications of diabetes, as psychological factors can hinder successful management of the condition and adversely affect metabolic control

Chitosan/gelatin scaffolds support bone regeneration

Chitosan/Gelatin (CS:Gel) scaffolds were fabricated by chemical crosslinking with glutaraldehyde or genipin by freeze drying. Both crosslinked CS:Gel scaffold types with a mass ratio of 40:60% form a gel-like structure with interconnected pores. Dynamic rheological measurements provided similar values for the storage modulus and the loss modulus of the CS:Gel scaffolds when crosslinked with the same concentration of glutaraldehyde vs. genipin. Compared to genipin, the glutaraldehyde-crosslinked scaffolds supported strong adhesion and infiltration of pre-osteoblasts within the pores as well as survival and proliferation of both MC3T3-E1 pre-osteoblastic cells after 7 days in culture, and human bone marrow mesenchymal stem cells (BM-MSCs) after 14 days in culture. The levels of collagen secreted into the extracellular matrix by the pre-osteoblasts cultured for 4 and 7 days on the CS:Gel scaffolds, significantly increased when compared to the tissue culture polystyrene (TCPS) control surface. Human BM-MSCs attached and infiltrated within the pores of the CS:Gel scaffolds allowing for a significant increase of the osteogenic gene expression of RUNX2, ALP, and OSC. Histological data following implantation of a CS:Gel scaffold into a mouse femur demonstrated that the scaffolds support the formation of extracellular matrix, while fibroblasts surrounding the porous scaffold produce collagen with minimal inflammatory reaction. These results show the potential of CS:Gel scaffolds to support new tissue formation and thus provide a promising strategy for bone tissue engineering. © 2018, Springer Science+Business Media, LLC, part of Springer Nature

Trans fatty acid intake increases likelihood of dyslipidemia especially among individuals with higher saturated fat consumption

Background: Evidence points to adverse effects of trans fatty acids (TFA) on health. The aim of this study was to estimate total TFA intake, evaluate major food contributors and its effect on dyslipidemia. Methods: A total of 3537 adults (48.3% males) were included. Total TFA intake was assessed using two 24-hour dietary recalls. Foods were categorized into specific food groups. Adjusted Logistic Regression analysis was performed to assess the likelihood of dyslipidemia by tertile of TFA aand Saturated Fatty Acid (SFA) level. Results: Median TFA intake was 0.53% of energy (from 0.34 to 0.81) ranging from 0.27 (Q1) to 0.95 (Q3) (p &lt; 0.001, for trend), and 16% of individuals consumed TFA above 1% of their total energy. Cheese was the main contributor to TFA intake, with processed/refined grains and fried fish following. The latter was the main contributor in older adults (51+ years). Adjusted logistic regression analysis showed that individuals at the highest tertile of trans consumption were 30% more likely to have dyslipidemia compared to the lowest (OR(Q3−Q1): 1.3; 95% CI: 1.02–1.66 and OR(Q2−Q1): 1.3; 95% CI:1.01–1.66, respectively). This increased by 10% when stratified by SFA intake (OR: 1.4; 95% CI: 1.061–1.942) and remained significant only in individuals at the highest tertile and with higher than recommended SFA intake. Conclusions: A high intake of TFA combined with high SFA intakes further increase the likelihood of dyslipidemia and should be accounted for in public health prevention programs. Monitoring and evaluation of the recent EU legislative measures on TFA levels in foods is also necessary. © 2022 The Author(s