Spin-dependent electronic conduction along zigzag graphene nanoribbons bearing adsorbed Ni and Fe nanostructures

Using SMEAGOL, an ab initio computational method that combines the non-equilibrium Green's function formalism with density-functional theory, we calculated spin-specific electronic conduction in systems consisting of single Fen and Nin nanostructures (n = 1−4) adsorbed on a hydrogen-passivated zigzag graphene nanoribbon. For each cluster we considered both ferromagnetically and antiferromagnetically coupled ribbon edges (Ferro-F and Ferro-A systems, respectively). Adstructures located laterally on Ferro-A ribbons caused significant transmittance loss at energies 0.6–0.25 eV below the Fermi level for one spin and 0.2–0.4 eV above the Fermi level for the other, allowing the potential use of these systems in transistors to create a moderately spin-polarized current of one or the other sign depending on the gate voltage. Ni₃ and Ni₄ clusters located at the centre of Ferro-F ribbons exhibited a strong spin-filtering effect in a narrow energy window around the Fermi level

Spin currents and filtering behavior in zigzag graphene nanoribbons with adsorbed molybdenum chains

By means of density-functional-theoretic calculations, we investigated the structural, electronic and transport properties of hydrogen-passivated zigzag graphene nanoribbons (ZGNRs) on which a one-atom-thick Mo chain was adsorbed (with or without one or two missing atoms), or in which the passivating hydrogen atoms were replaced by Mo atoms. Mo-passivated ZGNRs proved to be nonmagnetic. ZGNRs with an adsorbed defect-free Mo chain were most stable with the Mo atoms forming dimers above edge bay sites, which suppressed the magnetic moments of the C atoms in that half of the ribbon; around the Fermi level of these systems, each spin component had a transmission channel via the Mo spz band and one had an additional channel created by polarization of the ZGNR π* band, leading to a net spin current. The absence of an Mo dimer from an Mo chain adsorbed at the ZGNR edge made the system a perfect spin filter at low voltage bias by suppressing the Mo spz band channels. Thus this last kind of hybrid system is a potential spin valve

Nota sobre la pirofilita de Águilas (Murcia, SE de España)

Se hace un estudio previo del yacimiento de la pirofilita de Águilas (Provincia de Murcia, SE de España). Pirofilita, cuarzo, micas blancas y caolinita son los constituyentes de estas mineralizaciones filonianas que encajan enfisuras de las filitas del complejo Alpujárride. El origen de la pirofilita está relacionado con un proceso de metamorfismoregional de un material sedimentario rico en aluminio. La principal reacciónimplicada seria:1 Caolinita + 2 SiO2 = 1 Pirofilita + H2OSe contempla asimismo como posibilidad alternativa, un proceso de segregación metamórfica. Se dan datos ópticos, de análisis químico y de difracción de Rayos X

Pathological mandibular fracture after simple molar extraction in a patient with osteogenesis imperfecta treated with alendronate

Osteogenesis imperfecta (OI), is a heterogeneous group of inherited disorders of connective tissue characterized by bone fragility. Patients with this disease frequently suffer fractures, over 80% of the extremities due to the more intensive mechanical load. Fractures of the facial bones occur very infrequently. Several studies have proved that bisphosphonate therapy may be effective in reducing fracture risk in OI patients. We report here an unusual case of pathological mandibular fracture following simple molar extraction in an adult patient with OI type I and oral alendronic acid treatment. Extraction was atraumatical and without bone removal . Fracture was treated by internal fixation by plate osteosynthesis and additional mandibulomaxillary fixation (MMF). Bone healing after fracture treatment was completely normal and no clinical signs of osteoneocrosis were observed. To the best of our knowledge, this is an unusual complication even in this type of patients. Particular care is necessary is these patients during oral surgery, even when they have been treated and controlled

Cartografía geomorfológica y procesos de activos en la cuenca media-alta del río Eria mediante técnicas de SIG.( Provincia de León, España)

El objetivo es la elaboración de la cartografía geomorfológica y de procesos geológicos activos de un tramo del curso medio de la cuenca del río Eria, en el sector suroccidental de la provincia de León utilizando técnicas de SIG. El trabajo se ha basado en la fotointerpretación de fotos aéreas en visión estereoscópica, estudio bibliográfico y aplicación de técnicas de SIG para el análisis de modelos digitales de terreno y mapas derivados (pendientes, alturas…) y para la representación cartográfica. Como resultado se distinguen tres dominios de relieve caracterizados por diferentes procesos geológicos: dominio de los relieves sobre sustrato paleozoico, dominio de los relieves de origen fluvial y dominio de las formas de origen antrópico. En el primero tienen gran relevancia las formas del relieve relacionadas con la estructura geológica hercínica, en donde aparecen procesos activos ligados a procesos gravitacionales, originando formas del relieve como canchales, coluviones, depósitos de piedemonte y. Debido a lo escarpado de este dominio, apenas existen infraestructuras humanas, por lo que la interferencia de los procesos activos con las mismas es baja. En el segundo dominio aparecen formas del relieve originadas por procesos activos relacionados con el encajamiento de la red fluvial y de sedimentación, pudiendo afectar a infraestructuras humanas. En el tercero aparecen actuaciones susceptibles de interferir con los procesos activos naturales, provocando efectos adversos para la población. La información cartográfica obtenida supone la base para un análisis de susceptibilidad espacial de los distintos peligros de origen geológico, útil para la planificación territorial.The aim of this work is to represent by means of GIS techniques the geomorphological and active geological processes map of the middle course of the Eria river, located in the southwestern León province, Spain. This study is based on aerial photointerpretation, bibliographic analysis of previous works, and on the application of GIS techniques. These techniques were used for the representation of the mapping units, and for analyzing a DTM and derived maps (slop, aspect, etc.), creating a spatial and attribute database.Three main relief domains were differentiated based on the predominant active geological processes: the domain of landforms developed on the Palaeozoic metamorphic rocks, the domain of fluvial landforms, and the domain of anthropogenic landforms. The first one is mainly related to active gravitational processes, but because of the low human occupation, the interaction with human infrastructures is almost negligible. The second one is mainly related to incision and sedimentation of the drainage network, interacting with some human infrastructures developed on the floodplains, alluvial fans and close to the river side. The third one is formed by human elements affecting and modifying at different levels the strength of the active geological processes. The resulting map act as a basis for further spatial susceptibility for geological hazards analysis, which is useful for land use planning

Nota corta. Aplicación de la ultrasonografía transrectal en el diagnóstico precoz de gestación y evaluación de la mortalidad embrionaria/fetal en ciervas ibéricas mantenidas en granja

[EN]: The main objective of the present study was to evaluate the accuracy of the trans-rectal ultrasonography technique applied to the Iberian red deer hinds since it has not been previously documented in Spain. Experimentation was also used to test the hypothesis that a lower fertility in young hinds could be due to an increment in embryonic or foetal mortality. For this purpose, 116 hinds divided in three groups depending on its age (young, adults and senescent) were examined by rectal ultrasonography and the different foetal structures measured two months after the males were removed from the groups of hinds. With these data, specificity and predictive value of negative diagnoses of the technique has been calculated. Trans-rectal ultrasonography is an accurate technique to use in Iberian red deer dams with overall levels of pregnant detection near to 92%. Finally, the youngest hinds showed poorer fertility rates (17.24% vs. 59.30% and 58.33% of senescent and prime-age respectively) and also higher of embryonic or foetal mortality (2 deaths out of 7 positive pregnant diagnoses compared with no deaths in the senescent group and 4 deaths out of 39 positive pregnant diagnoses in the prime-age group).[ES]: El objetivo principal del presente estudio ha sido evaluar la precisión de la ultrasonografía transrectal aplicada a las ciervas ibéricas, ya que no ha sido documentado previamente en España. Paralelamente, se ha intentado comprobar la hipótesis de que la menor fertilidad en las hembras más jóvenes podría deberse a una mayor mortalidad embrionariofetal. Para ello, 116 hembras divididas en tres grupos en función de su edad (jóvenes, adultas y viejas) fueron ecografiadas a los 2 meses de la retirada de los machos y medidas las diferentes estructuras fetales. Con estos datos se ha calculado la especificidad y seguridad en el diagnóstico negativo de la técnica. La ultrasonografía transrectal es una técnica precisa para su uso en ciervas ibéricas, con niveles de detección de gestación cercanos al 92%. Finalmente, las ciervas más jóvenes muestran peores índices de fertilidad (17,24% vs 59,30% y 58,33% del grupo de viejas y adultas respectivamente) y mayores mortalidades embrionario-fetales (2 muertes de 7 diagnósticos gestantes positivos en comparación con ninguna muerte en el grupo de hembras de más edad y con 4 muertes de 39 diagnósticos gestantes en las hembras adultas).Peer Reviewe

Structure-function dissection of Myxococcus xanthus CarD N-terminal domain, a defining member of the CarD-CdnL-TRCF family of RNA polymerase interacting proteins

© 2015 Bernal-Bernal et al. Two prototypes of the large CarD-CdnL-TRCF family of bacterial RNA polymerase (RNAP)-binding proteins, Myxococcus xanthus CarD and CdnL, have distinct functions whose molecular basis remain elusive. CarD, a global regulator linked to the action of several extracytoplasmic function (ECF) σ-factors, binds to the RNAP β subunit (RNAP-β) and to protein CarG via an N-terminal domain, CarDNt, and to DNA via an intrinsically unfolded C-terminal domain resembling eukaryotic high-mobility-group A (HMGA) proteins. CdnL, a CarDNt-like protein that is essential for cell viability, is implicated in σA-dependent rRNA promoter activation and interacts with RNAP-β but not with CarG. While the HMGA-like domain of CarD by itself is inactive, we find that CarDNt has low but observable ability to activate ECF σ-dependent promoters in vivo, indicating that the C-terminal DNA-binding domain is required to maximize activity. Our structure-function dissection of CarDNt reveals an N-terminal, five-stranded β-sheet Tudor-like domain, CarD1-72, whose structure and contacts with RNAP-β mimic those of CdnL. Intriguingly, and in marked contrast to CdnL, CarD mutations that disrupt its interaction with RNAP-β did not annul activity. Our data suggest that the CarDNt C-terminal segment, CarD61-179, may be structurally distinct from its CdnL counterpart, and that it houses at least two distinct and crucial function determinants: (a) CarG-binding, which is specific to CarD; and (b) a basic residue stretch, which is also conserved and functionally required in CdnL. This study highlights the evolution of shared and divergent interactions in similar protein modules that enable the distinct activities of two related members of a functionally important and widespread bacterial protein family.Peer Reviewe

Present and future of the OTELO project

OTELO is an emission-line object survey carried out with the red tunable filter of the instrument OSIRIS at the GTC, whose aim is to become the deepest emission-line object survey to date. With 100% of the data of the first pointing finally obtained in June 2014, we present here some aspects of the processing of the data and the very first results of the OTELO survey. We also explain the next steps to be followed in the near future.Comment: Oral contribution presented in the XI Scientific Meeting of the Spanish Astronomical Society held on September 8-12, in Teruel, Spain (7 pages, 2 figures, 1 table). To appear in Highlights of Spanish Astrophysics VIII, Proceedings of the XI Scientific Meeting of the Spanish Astronomical Society. Eds. A. J. Cenarro, F. Figueras, C. Hern\'andez-Monteagudo, J. Trujillo, L. Valdiviels

Caracterización energética de la unión de 1,3,6- naftalén trisulfonato al factor de crecimiento para fibroblastos ácido humano: implicaciones para su uso como agente anti-angiogénico

The equilibrium interaction of anti-cancer agent 1,3,6-naphatalene trisulfonate with human acidic fi broblast growthfactor has been studied by calorimetry. The affi nity decreases with increasing ionic strength. At pH 7.0 and 0.15 MNaCl concentration, a binding constant of the protein with the ligand was estimated in the 102 – 103 M-1 range, anaffi nity two orders of magnitude lower than that of aFGF with heparin. The interaction is enthalpically driven, andthe entropy change is unfavorable. A small heat capacity change with an unusual positive value of 90 cal K-1mol-1 wasdetermined from the temperature dependence of the enthalpies. Changes in accessible apolar and polar surface areasin the interaction were calculated from the thermodynamic data obtained and parametric equations in the literature.The results were compared with those measured from NMR data. The study includes structural bioenergetic considerationsabout the possible use of 1,3,6-naphatalene trisulfonate as an anti-angiogenic agent itself, or as a lead for thedevelopment of anti-angiogenic drugs.Se ha estudiado, mediante calorimetría isotérmica de reacción, la interacción del agente anticancerígeno 1,3,6-naftaléntrisulfonato con el factor de crecimiento para fi broblastos ácido humano. La afi nidad decrece con el aumento de lafuerza iónica. A pH 7,0 y NaCl 0,15 M, la constante de unión de la proteína con el ligando se encuentra en el rango102 – 103 M-1, una afi nidad dos órdenes de magnitud menor que la del FGFa por heparina. El cambio de entalpíafavorece la interacción, siendo el cambio de entropía desfavorable. De la dependencia del cambio de entalpía con latemperatura se calculó un pequeño cambio en la capacidad calorífi ca del proceso, con un valor excepcionalmentepositivo de 90 cal K-1mol-1. A partir de los datos termodinámicos medidos y de ecuaciones paramétricas establecidasen la literatura, se calcularon cambios en la superfi cie accesible al disolvente, tanto polar como apolar, que acompañana la interacción. Los resultados se compararon con los medidos mediante resonancia magnética nuclear. Elestudio incluye consideraciones de bioenergética estructural sobre el posible uso de 1,3,6-naftalén trisulfonato comoagente antiangiogénico o como molécula líder para el desarrollo de fármacos anti-angiogénicos