1,552 research outputs found

    Better Regulation for Sustainable Development

    Get PDF
    © Sustainable Development Commission 2009This discussion paper considers the case for using regulation as a lever to promote sustainable development in public services.Sustainable Development Commissio

    Synthesis of (±)-Panduratin A and Related Natural Products Using the High Pressure Diels-Alder Reaction

    No full text
    Panduratin A and 4-hydroxypanduratin A are synthesised in 6 steps via a high pressure Diels-Alder reaction. This sequence has also allowed the synthesis of isopanduratin A, 4-hyrdoxyisopanduratin A, panduratin H, and panduratin I. In addition the regioselectivity of the Diels-Alder reaction has been investigated.We thank the Australian Research Council for financial support. M.L.C thanks the National Facility of the National Computational Infrastructure for supercomputing time

    Reflections and Speculations on Teaching and Learning in Public Administration

    Get PDF
    The scale and impact of the current global financial and economic crisis affect not just the public and political institutions established to manage the economy, but also those programmes in institutions of higher education which seek to work with professionals, practitioners and decision makers. If we can witness a public crisis of confidence in the capacity of our existing family of institutions to manage the change, then we might expect to observe similar changes in universities, too. This article reflects upon the nature of the relationships between universities (business and management schools) and the wider public and political community. It also attempts to anticipate some of the potential consequences of the crisis in terms of how the academy might reflect upon its assumptions concerning teaching and learning approaches, and expectations within the discipline of public administration. We suggest that the present crisis is an opportunity to think about the curriculum and pedagogic choices we make and to promote a more collaborative approach to learning, drawing upon models of reflection and professional practice to be found across different disciplines including social work and teaching

    The breakdown of the municipality as caring platform: lessons for co-design and co-learning in the age of platform capitalism

    Get PDF
    If municipalities were the caring platforms of the 19-20th century sharing economy, how does care manifest in civic structures of the current period? We consider how platforms - from the local initiatives of communities transforming neighbourhoods, to the city, in the form of the local authority - are involved, trusted and/or relied on in the design of shared services and amenities for the public good. We use contrasting cases of interaction between local government and civil society organisations in Sweden and the UK to explore trends in public service provision. We look at how care can manifest between state and citizens and at the roles that co-design and co-learning play in developing contextually sensitive opportunities for caring platforms. In this way, we seek to learn from platforms in transition about the importance of co-learning in political and structural contexts and make recommendations for the co-design of (digital) platforms to care with and for civil society

    Use of a dual reporter plasmid to demonstrate bactofection with an attenuated aroa- derivative of Pasteurella multocida b:2

    Get PDF
    A reporter plasmid pSRG has been developed which expresses red fluorescent protein (RFP) from a constitutive prokaryotic promoter within Pasteurella multocida B:2 and green fluorescent protein (GFP) from a constitutive eukaryotic promoter within mammalian cells. This construct has been used to determine the location and viability of the bacteria when moving from the extracellular environment into the intracellular compartment of mammalian cells. Invasion assays with embryonic bovine lung (EBL) cells and an attenuated AroA- derivative of Pasteurella multocida B:2 (strain JRMT12), harbouring the plasmid pSRG, showed that RFP-expressing bacteria could be detected intracellularly at 3 h post-invasion. At this stage, some EBL cells harbouring RFP-expressing bacteria were observed to express GFP simultaneously, indicating release of the plasmid into the intracellular environment. At 5 h post-invasion, more EBL cells were expressing GFP, while still harbouring RFP-expressing bacteria. Concurrently, some EBL cells were shown to express only GFP, indicating loss of viable bacteria within these cells. These experiments proved the functionality of the pSRG dual reporter system and the potential of P. multocida B:2 JRMT12 for bactofection and delivery of a DNA vaccine

    Using a realist approach to evaluate smoking cessation interventions targeting pregnant women and young people

    Get PDF
    Background This paper describes a study protocol designed to evaluate a programme of smoking cessation interventions targeting pregnant women and young people living in urban and rural locations in Northeast Scotland. The study design was developed on so-called 'realist' evaluation principles, which are concerned with the implementation of interventions as well as their outcomes. Methods/design A two-phased study was designed based on the Theory of Change (TOC) using mixed methods to assess both process and outcome factors. The study was designed with input from the relevant stakeholders. The mixed-methods approach consists of semi-structured interviews with planners, service providers, service users and non-users. These qualitative interviews will be analysed using a thematic framework approach. The quantitative element of the study will include the analysis of routinely collected data and specific project monitoring data, such as data on service engagement, service use, quit rates and changes in smoking status. Discussion The process of involving key stakeholders was conducted using logic modelling and TOC tools. Engaging stakeholders, including those responsible for funding, developing and delivering, and those intended to benefit from interventions aimed at them, in their evaluation design, are considered by many to increase the validity and rigour of the subsequent evidence generated. This study is intended to determine not only the components and processes, but also the possible effectiveness of this set of health interventions, and contribute to the evidence base about smoking cessation interventions aimed at priority groups in Scotland. It is also anticipated that this study will contribute to the ongoing debate about the role and challenges of 'realist' evaluation approaches in general, and the utility of logic modelling and TOC approaches in particular, for evaluation of complex health interventions

    Exclusionary employment in Britain’s broken labour market

    Get PDF
    There is growing evidence of the problematic nature of the UK’s ‘flexible labour market’ with rising levels of in-work poverty and insecurity. Yet successive Governments have stressed that paid work is the route to inclusion, focussing attention on the divide between employed and unemployed. Past efforts to measure social exclusion have tended to make the same distinction. The aim of this paper is to apply Levitas et al’s (2007) framework to assess levels of exclusionary employment, i.e. exclusion arising directly from an individual’s labour market situation. Using data from the Poverty and Social Exclusion UK survey, results show that one in three adults in paid work is in poverty, or in insecure or poor quality employment. One third of this group have not seen any progression in their labour market situation in the last five years. The policy focus needs to shift from ‘Broken Britain’ to Britain’s broken labour market

    Emerging school sport development policy, practice and governance in England: Big Society, autonomy and decentralisation

    Get PDF
    International interest in developing mass sports participation through systems of school and community sports development has become a growing field of public leisure policy interest. This research paper considers the policy change from School Sport Partnerships to the new 2012 School Games model of networked partnerships to establish characteristics of the changes in governance modes and implications from practice in England. The research project is based on a regional case study drawing upon indepth,face-to-face interviews with key public policy stakeholders to inform an analysis of change. Initial findings indicate that the emergent networks are characterised by more networked-based mode of governance than previous hierarchical models present under UK New Labour. The study also shows the fragility of a reliance on partnership structures and the potential implications for incongruence in delivering policy outcomes and improving access to physical activity and school sport opportunities
    corecore