Study on the Treatment of High Concentrated Industrial Wastewater Containing Phenol and Aldehyde with Fenton/UV Oxidation Method

酚醛树脂具有优越的综合性能，而且价格低廉，能制成多种产品，是重要的合成树脂之一。然而，在制备酚醛树脂时会产生大量的酚醛废水，废水组成复杂，含有多种难处理的有机物，而且有机物浓度高（即化学需氧量COD高），具有很强的毒性，直接排放将对环境产生很大的危害。采用一般的处理方法难以实现好的效果，芬顿试剂（Fenton）是由过氧化氢和亚铁离子组成的试剂，过氧化氢在亚铁离子的催化作用下氧化能力强，可以对多种难处理的有机物进行有效的氧化降解，但国内主要报道了用该试剂处理实验室模拟的含酚或者含醛废水，对实际工业酚醛废水的处理研究较少，对酚醛废水有机物氧化降解途径的探究也不够详细，而且废水处理的操作方法复杂，效...With the advantages of excellent comprehensive performance and low cost, phenolic resin is widely used with high yield. However, during the process of phenolic resin production, A large amount of high concentrated wastewater is also produced, components of which are very complex, containing both phenols and aldehydes, and the chemical oxygen demand (COD) can reach as high as tens of thousands mill...学位：理学硕士院系专业：材料学院_高分子化学与物理学号：2072012115005

<Brief Notes>The Actual Situation "The Dormitory Education" in Special Needs Education School for the Visually Impaired

departmental bulletin pape

保育者は自らの服装の色彩をどのように決定しているのか : 混合研究法による保育者の服装の色彩印象評価の分析より

　本研究では、保育者の服装の色彩による印象評価について、SD法を用いて印象評価尺度の作成し、その尺度をもとに、保育者のエプロンの色彩に対する他者の印象評価の特徴などについて考察を行う。そして、その結果をもとに、グループ・フォーカス・インタビューを実施し、保育実践において保育者が自らの被服の選択において、色彩のあり方をどのように意識しているのかを明らかにする

看護学および社会福祉学領域におけるコーパス言語学的アプローチの基礎研究

本稿は、岡山県立大学大学院前期課程の専攻共通科目である「国際コミュニケーション特論」で取り上げたコーパス言語学と内容分析を用いて、履修者が共同執筆者として各自の研究テーマの一端を解明するものである。本稿では、分析対象として共通の看護社会福祉領域コーパスを作成し、それを基に分析対象語を抽出した。そして、分析対象語を含む言葉の意味的まとまり（ディスコースおよびディスコース・セグメント）に対して内容分析を試みた。本稿は、複数の執筆者によるオムニバス的論考であるため、考察結果も様々であるが、看護学および社会福祉学領域へのコーパス言語学的アプローチの推進のために、速報的・記録的にまとめた研究プロポーザル的要素を含むものである。This study employs the application of corpus linguistics and content analysis in nursing and social welfare studies. The two linguistic methods were dealt in a graduate-level class, Global Communication Study, and the registered students of the class pursued their own research themes using the two methods. Hence, this study is an accumulation of each student’s research results. However, this paper has a significant meaning as a research proposal since linguistics is not yet a popular approach in nursing and social welfare studies. This paper shows an affinity, to some extent, between linguistics and nursing and social welfare studies and will have a positive impact on further research in the field of the two studies

RXRα acts as a carrier for TR3 nuclear export in a 9-cis retinoic acid-dependent manner in gastric cancer cells

Retinoid X receptor (RXR) plays a crucial role in the cross talk between retinoid receptors and other hormone receptors including the orphan receptor TR3, forming different heterodimers that transduce diverse steroid/thyroid hormone signaling. Here we show that RXRalpha exhibits nucleocytoplasmic shuttling in MGC80-3 gastric cancer cells and that RXRalpha, shuttling is energy-dependent through a nuclear pore complex (NPC)mediated pathway for its import and an intact DNA binding domain-mediated pathway for its export. In the presence of its ligand 9-cis retinoic acid, RXRalpha was almost exclusively located in the cytoplasm. More importantly, we also show that RXRalpha. acts as a carrier to assist translocation of TR3, which plays an important role in apoptosis. Both RXRalpha and TR3 colocalized in the nucleus; however, upon stimulation by 9-cis retinoic acid they cotranslocated to the cytoplasm and then localized in the mitochondria. TR3 export depends on RXRalpha as in living cells GFP-TR3 alone did not result in export from the nucleus even in the presence of 9-cis retinoic acid, whereas GFP-TR3 cotransfected with RXRalpha was exported out of the nucleus in response to 9-cis retinoic acid. Moreover, specific reduction of RXRalpha levels caused by anti-sense RXRalpha abolished TR3 nuclear export. In contrast, specific knockdown of TR3 by antisense-TR3 or TR3-siRNA did not affect RXRalpha shuttling. These results indicate that RXRalpha is responsible for TR3 nucleocytoplasmic translocation, which is facilitated by the RXRalpha ligand 9-cis retinoic acid. In addition, mitochondrial TR3, but not RXRalpha was critical for apoptosis, as TR3 mutants that were distributed in the mitochondria induced apoptosis in the presence or absence of 9-cis retinoic acid. These data reveal a novel aspect of RXRalpha function, in which it acts as a carrier for nucleocytoplasmic translocation of orphan receptors

组织变革中员工创新行为影响机制研究——以责任导向为调节变量

世界经济环境日趋复杂,企业竞争也愈加激烈,因此,变革已成为企业更好地生存和可持续发展的必然手段。对45家变革企业员工及其直属领导的访谈和实证研究表明,工作不安全感对员工创新行为有负面影响,变革情感承诺在其中起到了中介作用,员工的任务责任导向在员工变革情感承诺和员工创新行为之间起到了调节作用。国家自然科学基金项目(71402153

Metabolic phenotypes and incident type 2 diabetes: Population-based Panasonic cohort study 6.

京都府立医科大学博士（医学）令和5年度thesi

葡萄糖感应器及其AMPK活性和细胞代谢状态的调控机理

葡萄糖是细胞的主要能量来源,它通过糖酵解和/或氧化代谢产生ATP。葡萄糖水平下降将激活AMP活化蛋白激酶(AMP-activated protein kinase-AMPK),数十年来,人们一直认为这是由于AMP或ADP的上升,或者说能量水平的下降引起的。厦门大学生命科学学院林圣彩研究团队与英国Dundee大学D.Grahame Hardie团队合作报道了一种通过感知胞内葡萄糖代谢中间物果糖-1,6-二磷酸(FBP)的下降来触发AMPK活化的机制:FBP水平下降,便不再占据其催化酶——醛缩酶(aldolase)上的催化位点,后者直接改变了溶酶体膜上的质子泵v-ATPase和与其相结合的\"Ragulator\"的构象,进而让携带有能磷酸化并激活AMPK的上游激酶LKB1的AXIN蛋白质转移到溶酶体膜表面,在此形成了能激活AMPK的复合体(该复合体也是由林圣彩实验室发现并鉴定-Cell Metabolism,2013,2014),从而激活AMPK,同时抑制了促进细胞进行生物合成和生长的激酶-mTORC1。重要的是,他们从中也颠覆性地发现细胞能量水平在葡萄糖水平急速下降期间仍保持不变,且AMPK上的AMP结合位点对于此时AMPK的活化不是必需的。该研究不仅发现了醛缩酶这一糖酵解酶的新功能:调控AMPK的葡萄糖感受器,还深刻地揭示了葡萄糖的本质:既是能量和物质来源,也是直接调控细胞生物合成和生长状态的信号,对多种代谢型疾病的发生、癌症与代谢关系的认知与治疗、卡路里限制与健康长寿等的认知具有重大意义。相关研究论文在2017年8月3日发表于《自然》[NATURE,548(7665):112-116,August 2017]