Characteristics of food allergy in children: National multicenter study

Conference: Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI) Location: Lisbon, PORTUGAL Date: JUN 01-05, 2019Background : Food allergies impose a significant burden on the life of the child and the family. In this study, to determine the demographic characteristics of food allergies, we investigated the characteristics of patients with food allergies in different regions of Pediatric Allergy- Immunology departments in Turkey. Method : Turkey ' s National Study of Allergy and Clinical Immunology Society has conducted a Study Group on Food Allergies. 25 centers participated in this multicenter, cross- sectional and descriptive study.European Academy of Allergy and Clinical Immunolog

Outcomes of high-risk breast lesions diagnosed using image-guided core needle biopsy: results from a multicenter retrospective study

PURPOSEThe clinical management of high-risk lesions using image-guided biopsy is challenging. This study aimed to evaluate the rates at which such lesions were upgraded to malignancy and identify possible predictive factors for upgrading high-risk lesions.METHODSThis retrospective multicenter analysis included 1.343 patients diagnosed with high-risk lesions using an image-guided core needle or vacuum-assisted biopsy (VAB). Only patients managed using an excisional biopsy or with at least one year of documented radiological follow-up were included. For each, the Breast Imaging Reporting and Data System (BI-RADS) category, number of samples, needle thickness, and lesion size were correlated with malignancy upgrade rates in different histologic subtypes. Pearson’s chi-squared test, the Fisher–Freeman–Halton test, and Fisher’s exact test were used for the statistical analyses.RESULTSThe overall upgrade rate was 20.6%, with the highest rates in the subtypes of intraductal papilloma (IP) with atypia (44.7%; 55/123), followed by atypical ductal hyperplasia (ADH) (38.4%; 144/375), lobular neoplasia (LN) (12.7%; 7/55), papilloma without atypia (9.4%; 58/611), flat epithelial atypia (FEA) (8.7%; 10/114), and radial scars (RSs) (4.6%; 3/65). There was a significant relationship between the upgrade rate and BI-RADS category, number of samples, and lesion size Lesion size was the most predictive factor for an upgrade in all subtypes.CONCLUSIONADH and atypical IP showed considerable upgrade rates to malignancy, requiring surgical excision. The LN, IP without atypia, pure FEA, and RS subtypes showed lower malignancy rates when the BI-RADS category was lower and in smaller lesions that had been adequately sampled using VAB. After being discussed in a multidisciplinary meeting, these cases could be managed with follow-up instead of excision

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Universities’ use of Instagram in the context of communication: The TRNC example

Social media has become a necessity for people. The fact remains that, the increase in the number of users of social media platforms and the fact that they spend a lot of time on social media cause some differences in the influence of users, in the desired direction of thinking and the need for verification. Recently, Instagram is among the platforms most used by university students. Starting from this, this study investigates how universities in TRNC use Instagram accounts in the context of communication. In line with this goal, the research, the posts shared by the five universities in the Turkish Republic of Northern Cyprus, which have the most Instagram followers, in the fall semester of the 2021-2022 academic year, were analyzed by content analysis method. The posts were handled in 5 categories: news - announcement, promotion, culture, art, sports, social responsibility and special day. As a result of the study, the Instagram accounts of the universities were analyze

Türkiye’de hayvan hakları

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2015.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Aslan, Mustafa Çağatay

Diffuse alveolar haemorrhage following an insect bite

Diffüz alveolar hemorajinin çoklu etyolojik nedeni vardır. Sistemik hastalıklardan, çevresel toksinlere, immünolojik nedenlerden, kardiyak patolojilere kadar perspektif genişletilebilir. Böcek ısırıkları sonrası en sık lokal eritem ile sınırlı Ig E aracılı allerjik reaksiyonlar görülür. Sistemik reaksiyon çok az olguda bildirilmiştir. Biz bu yazıda, böcek ısırığı sonrasında gelişen diffüz alveoler hemoraji olgusunu sunuyoruz.Many disorders can cause alveolar hemorrhage including systemic diseases, environmental toxic exposures, autoimmune disorders, and cardiac disorders. The first symptom of the insect sting is IgE mediated local erythema and pain. Systemic reaction to insect sting is an uncommon manifestation and reported in a few cases. In this article we describe a case who developed diffuse pulmonary alveolar hemorrhage following an insect bite

Diffuse alveolar haemorrhage following an insect bite

Diffüz alveolar hemorajinin çoklu etyolojik nedeni vardır. Sistemik hastalıklardan, çevresel toksinlere, immünolojik nedenlerden, kardiyak patolojilere kadar perspektif genişletilebilir. Böcek ısırıkları sonrası en sık lokal eritem ile sınırlı Ig E aracılı allerjik reaksiyonlar görülür. Sistemik reaksiyon çok az olguda bildirilmiştir. Biz bu yazıda, böcek ısırığı sonrasında gelişen diffüz alveoler hemoraji olgusunu sunuyoruz.Many disorders can cause alveolar hemorrhage including systemic diseases, environmental toxic exposures, autoimmune disorders, and cardiac disorders. The first symptom of the insect sting is IgE mediated local erythema and pain. Systemic reaction to insect sting is an uncommon manifestation and reported in a few cases. In this article we describe a case who developed diffuse pulmonary alveolar hemorrhage following an insect bite

Micro-IDE : A tool platform for generating efficient deployment alternatives based on microservices

Microservice architecture (MSA) is a paradigm to design and develop scalable distributed applications using loosely coupled, highly cohesive components that can be deployed independently. The applications that realize the MSA may contain thousands of services that together form the overall system. Microservices interact with each other by producing and consuming data. Deploying frequently communicating services to the same physical resource would reduce network utilization, which is vital for reducing costs and improving scalability. Since the physical resources have limited capacity, it is not always possible to deploy communicating services to the same resource. Therefore, automated efficient deployment alternatives need to be generated for MSA in the design phase. To address this problem, we proposed an algorithmic approach to generate efficient microservice deployment configurations to available cloud resources in our previous study. In this study, a tool (Micro-IDE) has been proposed to realize and evaluate this approach. The Micro-IDE tool has been validated using a case study inspired by the Spotify application