Structured and Unstructured Information Extraction Using Text Mining and Natural Language Processing Techniques

Information on web is increasing at infinitum. Thus, web has become an unstructured global area where information even if available, cannot be directly used for desired applications. One is often faced with an information overload and demands for some automated help. Information extraction (IE) is the task of automatically extracting structured information from unstructured and/or semi-structured machine-readable documents by means of Text Mining and Natural Language Processing (NLP) techniques. Extracted structured information can be used for variety of enterprise or personal level task of varying complexity. The Information Extraction (IE) in also a set of knowledge in order to answer to user consultations using natural language. The system is based on a Fuzzy Logic engine, which takes advantage of its flexibility for managing sets of accumulated knowledge. These sets may be built in hierarchic levels by a tree structure. Information extraction is structured data or knowledge from unstructured text by identifying references to named entities as well as stated relationships between such entities. Data mining research assumes that the information to be “mined” is already in the form of a relational database. IE can serve an important technology for text mining. The knowledge discovered is expressed directly in the documents to be mined, then IE alone can serve as an effective approach to text mining. However, if the documents contain concrete data in unstructured form rather than abstract knowledge, it may be useful to first use IE to transform the unstructured data in the document corpus into a structured database, and then use traditional data mining tools to identify abstract patterns in this extracted data. We propose a novel method for text mining with natural language processing techniques to extract the information from data base with efficient way, where the extraction time and accuracy is measured and plotted with simulation. Where the attributes of entities and relationship entities from structured and semi structured information .Results are compared with conventional methods

Mapping the human genetic architecture of COVID-19

The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3,4,5,6,7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease

Additional file 4 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

Additional file 4: Supplemental results.1. README. 2. Prevalence range across districts. 3. Prevalence range between sexes. 4. Prevalence range between ages. 5. Age-specific district ranges