Markov models for fMRI correlation structure: is brain functional connectivity small world, or decomposable into networks?

Correlations in the signal observed via functional Magnetic Resonance Imaging (fMRI), are expected to reveal the interactions in the underlying neural populations through hemodynamic response. In particular, they highlight distributed set of mutually correlated regions that correspond to brain networks related to different cognitive functions. Yet graph-theoretical studies of neural connections give a different picture: that of a highly integrated system with small-world properties: local clustering but with short pathways across the complete structure. We examine the conditional independence properties of the fMRI signal, i.e. its Markov structure, to find realistic assumptions on the connectivity structure that are required to explain the observed functional connectivity. In particular we seek a decomposition of the Markov structure into segregated functional networks using decomposable graphs: a set of strongly-connected and partially overlapping cliques. We introduce a new method to efficiently extract such cliques on a large, strongly-connected graph. We compare methods learning different graph structures from functional connectivity by testing the goodness of fit of the model they learn on new data. We find that summarizing the structure as strongly-connected networks can give a good description only for very large and overlapping networks. These results highlight that Markov models are good tools to identify the structure of brain connectivity from fMRI signals, but for this purpose they must reflect the small-world properties of the underlying neural systems

Distributed Regression in Sensor Networks: Training Distributively with Alternating Projections

Wireless sensor networks (WSNs) have attracted considerable attention in recent years and motivate a host of new challenges for distributed signal processing. The problem of distributed or decentralized estimation has often been considered in the context of parametric models. However, the success of parametric methods is limited by the appropriateness of the strong statistical assumptions made by the models. In this paper, a more flexible nonparametric model for distributed regression is considered that is applicable in a variety of WSN applications including field estimation. Here, starting with the standard regularized kernel least-squares estimator, a message-passing algorithm for distributed estimation in WSNs is derived. The algorithm can be viewed as an instantiation of the successive orthogonal projection (SOP) algorithm. Various practical aspects of the algorithm are discussed and several numerical simulations validate the potential of the approach.Comment: To appear in the Proceedings of the SPIE Conference on Advanced Signal Processing Algorithms, Architectures and Implementations XV, San Diego, CA, July 31 - August 4, 200

Information decomposition of multichannel EMG to map functional interactions in the distributed motor system

The central nervous system needs to coordinate multiple muscles during postural control. Functional coordination is established through the neural circuitry that interconnects different muscles. Here we used multivariate information decomposition of multichannel EMG acquired from 14 healthy participants during postural tasks to investigate the neural interactions between muscles. A set of information measures were estimated from an instantaneous linear regression model and a time-lagged VAR model fitted to the EMG envelopes of 36 muscles. We used network analysis to quantify the structure of functional interactions between muscles and compared them across experimental conditions. Conditional mutual information and transfer entropy revealed sparse networks dominated by local connections between muscles. We observed significant changes in muscle networks across postural tasks localized to the muscles involved in performing those tasks. Information decomposition revealed distinct patterns in task-related changes: unimanual and bimanual pointing were associated with reduced transfer to the pectoralis major muscles, but an increase in total information compared to no pointing, while postural instability resulted in increased information, information transfer and information storage in the abductor longus muscles compared to normal stability. These findings show robust patterns of directed interactions between muscles that are task-dependent and can be assessed from surface EMG recorded during static postural tasks. We discuss directed muscle networks in terms of the neural circuitry involved in generating muscle activity and suggest that task-related effects may reflect gain modulations of spinal reflex pathways

Spectral identification of networks using sparse measurements

We propose a new method to recover global information about a network of interconnected dynamical systems based on observations made at a small number (possibly one) of its nodes. In contrast to classical identification of full graph topology, we focus on the identification of the spectral graph-theoretic properties of the network, a framework that we call spectral network identification. The main theoretical results connect the spectral properties of the network to the spectral properties of the dynamics, which are well-defined in the context of the so-called Koopman operator and can be extracted from data through the Dynamic Mode Decomposition algorithm. These results are obtained for networks of diffusively-coupled units that admit a stable equilibrium state. For large networks, a statistical approach is considered, which focuses on spectral moments of the network and is well-suited to the case of heterogeneous populations. Our framework provides efficient numerical methods to infer global information on the network from sparse local measurements at a few nodes. Numerical simulations show for instance the possibility of detecting the mean number of connections or the addition of a new vertex using measurements made at one single node, that need not be representative of the other nodes' properties.Comment: 3

Outlier detection techniques for wireless sensor networks: A survey

In the field of wireless sensor networks, those measurements that significantly deviate from the normal pattern of sensed data are considered as outliers. The potential sources of outliers include noise and errors, events, and malicious attacks on the network. Traditional outlier detection techniques are not directly applicable to wireless sensor networks due to the nature of sensor data and specific requirements and limitations of the wireless sensor networks. This survey provides a comprehensive overview of existing outlier detection techniques specifically developed for the wireless sensor networks. Additionally, it presents a technique-based taxonomy and a comparative table to be used as a guideline to select a technique suitable for the application at hand based on characteristics such as data type, outlier type, outlier identity, and outlier degree