A Hierarchical Method for Removal of Baseline Drift from Biomedical Signals: Application in ECG Analysis

Noise can compromise the extraction of some fundamental and important features from biomedical signals and hence prohibit accurate analysis of these signals. Baseline wander in electrocardiogram (ECG) signals is one such example, which can be caused by factors such as respiration, variations in electrode impedance, and excessive body movements. Unless baseline wander is effectively removed, the accuracy of any feature extracted from the ECG, such as timing and duration of the ST-segment, is compromised. This paper approaches this filtering task from a novel standpoint by assuming that the ECG baseline wander comes from an independent and unknown source. The technique utilizes a hierarchical method including a blind source separation (BSS) step, in particular independent component analysis, to eliminate the effect of the baseline wander. We examine the specifics of the components causing the baseline wander and the factors that affect the separation process. Experimental results reveal the superiority of the proposed algorithm in removing the baseline wander

Optimal ECG Signal Denoising Using DWT with Enhanced African Vulture Optimization

Cardiovascular diseases (CVDs) are the world's leading cause of death; therefore cardiac health of the human heart has been a fascinating topic for decades. The electrocardiogram (ECG) signal is a comprehensive non-invasive method for determining cardiac health. Various health practitioners use the ECG signal to ascertain critical information about the human heart. In this paper, the noisy ECG signal is denoised based on Discrete Wavelet Transform (DWT) optimized with the Enhanced African Vulture Optimization (AVO) algorithm and adaptive switching mean filter (ASMF) is proposed. Initially, the input ECG signals are obtained from the MIT-BIH ARR dataset and white Gaussian noise is added to the obtained ECG signals. Then the corrupted ECG signals are denoised using Discrete Wavelet Transform (DWT) in which the threshold is optimized with an Enhanced African Vulture Optimization (AVO) algorithm to obtain the optimum threshold. The AVO algorithm is enhanced by Whale Optimization Algorithm (WOA). Additionally, ASMF is tuned by the Enhanced AVO algorithm. The experiments are conducted on the MIT-BIH dataset and the proposed filter built using the EAVO algorithm, attains a significant enhancement in reliable parameters, according to the testing results in terms of SNR, mean difference (MD), mean square error (MSE), normalized root mean squared error (NRMSE), peak reconstruction error (PRE), maximum error (ME), and normalized root mean error (NRME) with existing algorithms namely, PSO, AOA, MVO, etc

Hybrid methods based on empirical mode decomposition for non-invasive fetal heart rate monitoring

This study focuses on fetal electrocardiogram (fECG) processing using hybrid methods that combine two or more individual methods. Combinations of independent component analysis (ICA), wavelet transform (WT), recursive least squares (RLS), and empirical mode decomposition (EMD) were used to create the individual hybrid methods. Following four hybrid methods were compared and evaluated in this study: ICA-EMD, ICA-EMD-WT, EMD-WT, and ICA-RLS-EMD. The methods were tested on two databases, the ADFECGDB database and the PhysioNet Challenge 2013 database. Extraction evaluation is based on fetal heart rate (fHR) determination. Statistical evaluation is based on determination of correct detection (ACC), sensitivity (Se), positive predictive value (PPV), and harmonic mean between Se and PPV (F1). In this study, the best results were achieved by means of the ICA-RLS-EMD hybrid method, which achieved accuracy(ACC) > 80% at 9 out of 12 recordings when tested on the ADFECGDB database, reaching an average value of ACC > 84%, Se > 87%, PPV > 92%, and F1 > 90%. When tested on the Physionet Challenge 2013 database, ACC > 80% was achieved at 12 out of 25 recordings with an average value of ACC > 64%, Se > 69%, PPV > 79%, and F1 > 72%.Web of Science8512185120

Novel Fourier Quadrature Transforms and Analytic Signal Representations for Nonlinear and Non-stationary Time Series Analysis

The Hilbert transform (HT) and associated Gabor analytic signal (GAS) representation are well-known and widely used mathematical formulations for modeling and analysis of signals in various applications. In this study, like the HT, to obtain quadrature component of a signal, we propose the novel discrete Fourier cosine quadrature transforms (FCQTs) and discrete Fourier sine quadrature transforms (FSQTs), designated as Fourier quadrature transforms (FQTs). Using these FQTs, we propose sixteen Fourier-Singh analytic signal (FSAS) representations with following properties: (1) real part of eight FSAS representations is the original signal and imaginary part is the FCQT of the real part, (2) imaginary part of eight FSAS representations is the original signal and real part is the FSQT of the real part, (3) like the GAS, Fourier spectrum of the all FSAS representations has only positive frequencies, however unlike the GAS, the real and imaginary parts of the proposed FSAS representations are not orthogonal to each other. The Fourier decomposition method (FDM) is an adaptive data analysis approach to decompose a signal into a set of small number of Fourier intrinsic band functions which are AM-FM components. This study also proposes a new formulation of the FDM using the discrete cosine transform (DCT) with the GAS and FSAS representations, and demonstrate its efficacy for improved time-frequency-energy representation and analysis of nonlinear and non-stationary time series.Comment: 22 pages, 13 figure

Review on Power Line Interference Removal from ECG Signal Using Adaptive and Error Filter

An ECG signal is basically an index of the functionality of the heart. For example, a physician can detect arrhythmia by studying abnormalities in the ECG signal. Since very fine features present in an ECG signal may convey important information, it is important to have the signal as clean as possible. Power line interference may be significant in electrocardiography. Often, a proper recording environment is not sufficient to avoid this interference. ECG signals polluted by power line noise of relatively large amplitude were the frequency of power line interference accurately at 50 Hz or 60 Hz, a sharp notch filter would be able to separate and eliminate the noise. The major difficulty is that the frequency can vary about fractions of a Hertz, or even a few Hertz. Two different approaches have been proposed in literature for this purpose notch filters and adaptive interference cancellers. Notch filters reduce the power line interference by suppressing predetermined frequencies. One of the possible alternatives to take frequency variations into account is the use of an external reference power line signal. An ideal EMI filter for ECG should act as a sharp notch filter to eliminate only the undesirable power line interference while automatically adapting itself to variations in the frequency and level of the noise. This technique, available by the use of adaptive filters only, is reported in literature and present serious practical difficulties and is difficult to implement

CaP: Cardiovascular Disease Prediction using a Delta Layer based Center Vector Activation-centric DCNN

Cardiac disease stands as a primary contributor to mortality, representing a prevalent category of chronic and life-threatening conditions. Therefore, early detection is imperative. While existing research has sought to predict heart disease (HD) through Electrocardiogram (ECG) signals, there remains room for enhancement. This study introduces a novel approach for early HD detection based on the Delta Layer with Center Vector Activation-centric Deep Convolutional Neural Network (DLCVA-DCNN) within its research framework, namely: CaP. Initially, the input ECG signals undergo preprocessing using a Weighted Covariance Kalman Filter (WCKF) to eliminate noise. Subsequently, the preprocessed data is bifurcated: one branch transforms it into a binary image, while the other decomposes the signal to identify peak segments. The decomposition employs the Bivariate Ensemble Empirical Mode Decomposition (BEEMD) method, and the Pan-Tompkins Algorithm (PTA) is applied to ascertain the highest-frequency segments. The coupling information is then extracted from these peaks. Simultaneously, depth features are extracted from the binary image. The Linear Approximate Functional Walrus Optimization Algorithm (LAFWOA) is employed to select pertinent features from the coupling and depth features. These selected features are input into the DLCVA-DCNN classifier to discriminate disease and standard signals. The experimental analysis compares the proposed methodology with conventional frameworks based on performance metrics, revealing that the proposed approach achieves higher accuracy than existing techniques

Filtering electrocardiographic signals using an unbiased and normalized adaptive noise reduction system

We present a novel unbiased and normalized adaptive noise reduction (UNANR) system to suppress random noise in electrocardiographic (ECG) signals. The system contains procedures for the removal of baseline wander with a two-stage moving-average filter, comb filtering of power-line interference with an infinite impulse response (IIR) comb filter, an additive white noise generator to test the system's performance in terms of signal-to-noise ratio (SNR), and the UNANR model that is used to estimate the noise which is subtracted from the contaminated ECG signals. The UNANR model does not contain a bias unit, and the coefficients are adaptively updated by using the steepest-descent algorithm. The corresponding adaptation process is designed to minimize the instantaneous error between the estimated signal power and the desired noise-free signal power. The benchmark MIT-BIH arrhythmia database was used to evaluate the performance of the UNANR system with different levels of input noise. The results of adaptive filtering and a study on convergence of the UNANR learning rate demonstrate that the adaptive noise-reduction system that includes the UNANR model can effectively eliminate random noise in ambulatory ECG recordings., leading to a higher SNR improvement than that with the same system using the popular least-mean-square (LMS) filter. The SNR improvement provided by the proposed UNANR system was higher than that provided by the system with the LMS filter, with the input SNR in the range of 5-20 dB over the 48 ambulatory ECG recordings tested. Crown Copyright (C) 2008 Published by Elsevier Ltd on behalf of IPEM. All rights reserved

Liikeartefaktat elektrokardiografiassa

Movement of the patient during electrocardiograph (ECG) recording is a severe source of artifacts. Recent technical developments have enabled ECG recording without continuous supervision by experts. However, ECG recording outside of hospitals is prone to poor quality and movement artifacts. Therefore, it is important to study how and how much ECG recordings are affected by movement. Movement artifacts can hide signal components or mimic them, which causes false negative or false positive detections. Methods to manage movement artifacts include both computational and non-computational approaches. Computational approaches include, for example, adaptive filtering and machine learning methods. Additional variables that correlate with the artifact sources can be utilized in artifact recognition. For example, acceleration, impedance, and pressure signals have been studied as possible movement references. These additional signals are recorded by sensors that are placed on the ECG electrodes or on the patient’s body. In this thesis, the effect of movement artifacts is quantified using a simulation. The simulation makes use of open ECG databases. This study investigates how automated ECG analysis is affected by incremental increase in the movement artifact level. According to the results QRS detection statistics worsen with increased artifact levels. Capturing a movement reference for ECG is studied by experimental research. ECG and inertial measurement unit signals were recorded during different movements in order to analyze the creation of movement artifacts and movement reference signals. According to the results, placement of the movement reference signal sensor has a significant effect on the results. Different movements are captured better by different sensors and affect different ECG leads with different strengths.Potilaan liike sydänsähkökäyrämittauksen (EKG) aikana on merkittävä artefaktien lähde. Viimeaikainen teknologinen kehitys on mahdollistanut EKG-mittauksen ilman asiantuntijoiden jatkuvaa valvontaa. EKG-mittaukset sairaalaolosuhteiden ulkopuolella ovat kuitenkin erityisen alttiita huonolle signaalilaadulle ja liikeartefaktoille. Tämän vuoksi on tärkeää tutkia, miten ja kuinka paljon liike vaikuttaa EKG-mittauksiin. Liikeartefaktat voivat joko peittää tai jäljitellä EKG-signaalin eri osia, aiheuttaen vääriä negatiivisia tai vääriä positiivisia havaintoja. Liikeartefaktojen vaikutusta voidaan vähentää sekä laskennallisten että muiden menetelmien avulla. Laskennallisia menetelmiä ovat esimerkiksi adaptiivinen suodatus ja koneoppimismenetelmät. Artefaktojen lähteen kanssa korreloivia muuttujia mittaamalla voidaan edistää artefaktojen tunnistusta EKG-signaalista. Esimerkiksi kiihtyvyys-, impedanssi- ja painesignaalien käyttöä liikereferensseinä on tutkittu. Kyseisiä referenssisignaaleja voidaan mitata EKG-elektrodeihin tai potilaan kehoon kiinnitettävillä sensoreilla. Liikeartefaktojen vaikutuksen suuruutta tutkitaan tässä työssä simulaation avulla. Simulaatiossa hyödynnetään avoimia EKG-tietokantoja. Tutkimuksessa tarkastellaan sitä, miten vähittäinen liikeartefaktatason kasvu vaikuttaa automaattiseen EKG-analyysiin. Tulosten mukaan QRS-detektioon liittyvät tilastot huononevat artefaktatason kasvaessa. Liikereferenssin luomista tarkastellaan kokeellisen tutkimuksen avulla. EKG- ja inertiamittausyksikkö-signaaleja mitattiin erilaisten liikkeiden aikana, jotta voitaisiin havainnoida liikeartefaktojen ja liikesignaalin syntymistä. Tulosten mukaan liikereferenssiä mittaavan sensorin sijoituspaikalla on merkittävä vaikutus tuloksiin. Tietyt liikkeet saadaan paremmin mitattua eri tavoin sijoitettujen sensorien avulla. Lisäksi liikkeet vaikuttavat eri vahvuuksilla eri EKG-kytkentöihin