39,752 research outputs found
Enabling e-Research in combustion research community
Abstract
This paper proposes an application of the Collaborative e-Science Architecture (CeSA) to enable e-Research in combustion research community. A major problem of the community is that data required for constructing modelling might already exist but scattered and improperly evaluated. That makes the collection of data for constructing models difficult and time-consuming. The decentralised P2P collaborative environment of the CeSA is well suited to solve this distributed problem. It opens up access to scattered data and turns them to valuable resources. Other issues of the community addressed here are the needs for computational resources, storages and interoperability amongst different data formats can also be addressed by the use of Grid environment in the CeSA
Collaborative e-science architecture for Reaction Kinetics research community
This paper presents a novel collaborative e-science architecture (CeSA) to address two challenging issues in e-science that arise from the management of heterogeneous distributed environments: (i) how to provide individual scientists an integrated environment to collaborate with each other in distributed, loosely coupled research communities where each member might be using a disparate range of tools; and (ii) how to provide easy access to a range of computationally intensive resources from a desktop. The Reaction Kinetics research community was used to capture the requirements and in the evaluation of the proposed architecture. The result demonstrated the feasibility of the approach and the potential benefits of the CeSA
Nanoinformatics: developing new computing applications for nanomedicine
Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges. While nanomaterials open up the possibility for developing new devices in many industrial and scientific areas, they also offer breakthrough perspectives for the prevention, diagnosis and treatment of diseases. In this paper, we analyze the different aspects of nanoinformatics and suggest five research topics to help catalyze new research and development in the area, particularly focused on nanomedicine. We also encompass the use of informatics to further the biological and clinical applications of basic research in nanoscience and nanotechnology, and the related concept of an extended ?nanotype? to coalesce information related to nanoparticles. We suggest how nanoinformatics could accelerate developments in nanomedicine, similarly to what happened with the Human Genome and other -omics projects, on issues like exchanging modeling and simulation methods and tools, linking toxicity information to clinical and personal databases or developing new approaches for scientific ontologies, among many others
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Cancer Informatics for Cancer Centers (CI4CC): Building a Community Focused on Sharing Ideas and Best Practices to Improve Cancer Care and Patient Outcomes.
Cancer Informatics for Cancer Centers (CI4CC) is a grassroots, nonprofit 501c3 organization intended to provide a focused national forum for engagement of senior cancer informatics leaders, primarily aimed at academic cancer centers anywhere in the world but with a special emphasis on the 70 National Cancer Institute-funded cancer centers. Although each of the participating cancer centers is structured differently, and leaders' titles vary, we know firsthand there are similarities in both the issues we face and the solutions we achieve. As a consortium, we have initiated a dedicated listserv, an open-initiatives program, and targeted biannual face-to-face meetings. These meetings are a place to review our priorities and initiatives, providing a forum for discussion of the strategic and pragmatic issues we, as informatics leaders, individually face at our respective institutions and cancer centers. Here we provide a brief history of the CI4CC organization and meeting highlights from the latest CI4CC meeting that took place in Napa, California from October 14-16, 2019. The focus of this meeting was "intersections between informatics, data science, and population science." We conclude with a discussion on "hot topics" on the horizon for cancer informatics
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Challenges of ultra large scale integration of biomedical computing systems
The NCRI Informatics Initiative is overseeing the implementation of an informatics
framework for the UK cancer research community. The framework advocates an integrated
multidisciplinary method of working between scientific and medical communities. Key to this
process is community adoption of high quality acquisition, storage, sharing and integration of
diverse data elements to improve knowledge of the causes, prevention and treatment of
cancer. The integration of the complex data and meta-data used by these multiple
communities is a significant challenge and there are technical, resource-based and
sociological issues to be addressed. In this paper we review progress aimed at establishing
the framework and outline key challenges in ultra large scale integration of biomedical
computing systems
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