2,304 research outputs found
On the Informational Comparison of Qualitative Fuzzy Measures
International audienceFuzzy measures or capacities are the most general representation of uncertainty functions. However, this general class has been little explored from the point of view of its information content, when degrees of uncertainty are not supposed to be numerical, and belong to a finite qualitative scale, except in the case of possibility or necessity measures. The thrust of the paper is to define an ordering relation on the set of qualitative capacities expressing the idea that one is more informative than another, in agreement with the possibilistic notion of relative specificity. To this aim, we show that the class of qualitative capacities can be partitioned into equivalence classes of functions containing the same amount of information. They only differ by the underlying epistemic attitude such as pessimism or optimism. A meaningful information ordering between capacities can be defined on the basis of the most pessimistic (resp. optimistic) representatives of their equivalence classes. It is shown that, while qualitative capacities bear strong similarities to belief functions, such an analogy can be misleading when it comes to information content
Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity.
The metabolism of two of benzene's phenolic metabolites, phenol and hydroquinone, by peroxidase enzymes has been studied in detail. Studies employing horseradish peroxidase and human myeloperoxidase have shown that in the presence of hydrogen peroxide phenol is converted to 4,4'-diphenoquinone and other covalent binding metabolites, whereas hydroquinone is converted solely to 1,4-benzoquinone. Surprisingly, phenol stimulates the latter conversion rather than inhibiting it, an effect that may play a role in the in vivo myelotoxicity of benzene. Indeed, repeated coadministration of phenol and hydroquinone to B6C3F1 mice results in a dramatic and significant decrease in bone marrow cellularity similar to that observed following benzene exposure. A mechanism of benzene-induced myelotoxicity is therefore proposed in which the accumulation and interaction of phenol and hydroquinone in the bone marrow and the peroxidase-dependent formation of 1,4-benzoquinone are important components. This mechanism may also be responsible, at least in part, for benzene's genotoxic effects, as 1,4-benzoquinone has been shown to damage DNA and is shown here to induce multiple micronuclei in human lymphocytes. Secondary activation of benzene's phenol metabolites in the bone marrow may therefore play an important role in benzene's myelotoxic and carcinogenic effects
Space Archeology Overview at Gordion: 2010 to 2012
In fiscal years 2010, 2011, and 2012, Compton Tucker was the principal investigator of a NASA Space Archaeology project that worked at Gordion, in Central Turkey. Tucker was assisted by an excellent team of co-workers including Joseph Nigro and Daniel Slayback of Science Systems Applications Incorporated, Jenny Strum of the University of New Mexico, and Karina Yager, a post doctoral fellow at NASA/GSFC. This report summaries their research activities at Gordion for the field seasons of 2010, 2011, and 2012. Because of the possible use of our findings at Gordion for tomb robbing there and/or the encouragement of potential tomb robbers using our geophysical survey methods to locate areas to loot, we have not published any of our survey results in the open literature nor placed any of these results on any web sites. These 2010- 2012 survey results remain in the confidential archives of the University of Pennsylvania's University Museum of Archaeology and Anthropology, the group that leads the Gordion Excavation and Research Project. Excavations are planned for 2013 at Gordion, including several that will be based upon the research results in this report. The site of Gordion in central Turkey, famous as the home of King Midas, whose father's intricately tied knot gave the site its name, also served as the center of the Phrygian kingdom that ruled much of Central Anatolia in Asia Minor during the early first millennium B.C. Gordion has been a University of Pennsylvania Museum of Archaeology and Anthropology excavation project since 1950, yet the site is incompletely published despite six decades of research. The primary obstacles related to the site and its preservation were two problems that NASA technology could address: (1) critical survey errors in the hundreds of maps and plans produced by the earlier excavators, most of which used mutually incompatible geospatial referencing systems, that prevented any systematic understanding of the site; and (2) agricultural encroachment upon the site that was compromising its archaeological integrity. Our NASA Space Archaeology proposal was written to address both of these problems. When we started working at Gordion in 2010, we added a third objective, (3) ground penetrating radar and magnetic geophysical surveys of threatened areas. The first objective our NASA Space Archaeology Project was to provide the University of Pennsylvania's Museum of Archaeology and Anthropology a system to rectify and incorporate all existing survey data from Gordion, including previous aerial photographs of the site, detailed site surveys, maps, and excavation plans, into a common mapping system. This was accomplished with a Geographic Information System (GIS) based upon a 60 cm Quickbird satellite image ortho-rectified using Shuttle Radar Topographic Mission (SRTM) 30 m digital elevation data and tied to a known datum at Gordion. This enabled the first accurate, multi-layer plan of this complex site, occupied almost continuously from the Bronze Age to the 1st millennium CE, and made possible Gordion's three-dimensional development for the first time
The Relationship between Physical Growth and Infant Behavioral Development in Rural Guatemala
The present study investigated the relationship between a number of anthropometric indices and behavioral development during the first 2 years of life in rural Guatemala. Length and weight were the indices most strongly correlated with behavioral development. If the effect of the infant\u27s length and weight was statistically controlled for, none of the other anthropometric variables explained a significant proportion of the variance in behavioral development. Con- trolling for length (or weight) assessed at the same age as the behavioral assessment, length (or weight) for younger ages was not significantly correlated with behavioral development. Changes in length or weight over time were correlated with changes in behavioral performance. We were unable to explain the association between physical growth and behavioral development by a number of variables including gestational age, nutrient intake, prevalence of disease, and familial characteristics
Pressure Modulator Radiometer (PMR) tests
The pressure modulator technique was evaluated for monitoring pollutant gases in the Earth's atmosphere of altitude levels corresponding to the mid and lower troposphere. Using an experimental set up and a 110 cm sample cell, pressure modulator output signals resulting from a range of gas concentrations in the sample cell were examined. Then a 20 cm sample cell was modified so that trace gas properties in the atmosphere could be simulated in the laboratory. These gas properties were measured using an infrared sensor
Aerodynamic-structural analysis of dual bladed helicopter systems
The aerodynamic and structural feasibility of the birotor blade concept is assessed. The inviscid flow field about the dual bladed rotor was investigated to determine the aerodynamic characteristics for various dual rotor blade placement combinations with respect to blade stagger, gap, and angle of attack between the two blades. The boundary layer separation on the rotors was studied and three dimensional induced drag calculations for the dual rotor system are presented. The thrust and power requirements of the rotor system were predicted. NASTRAN, employed as the primary modeling tool, was used to obtain a model for predicting in plane bending, out of plane bending, and the torsional behavior of the birotors. Local hub loads, blade loads, and the natural frequencies for the birotor configuration are discussed
Theory of Cylindrical Tubules and Helical Ribbons of Chiral Lipid Membranes
We present a general theory for the equilibrium structure of cylindrical
tubules and helical ribbons of chiral lipid membranes. This theory is based on
a continuum elastic free energy that permits variations in the direction of
molecular tilt and in the curvature of the membrane. The theory shows that the
formation of tubules and helical ribbons is driven by the chirality of the
membrane. Tubules have a first-order transition from a uniform state to a
helically modulated state, with periodic stripes in the tilt direction and
ripples in the curvature. Helical ribbons can be stable structures, or they can
be unstable intermediate states in the formation of tubules.Comment: 43 pages, including 12 postscript figures, uses REVTeX 3.0 and
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