216 research outputs found

    The Long Journey of Joshua Louis Hicks: A Voice from the Texas Working Class

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    Boosting Reading Comprehension Through Response Activities

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    This action research project was conducted to help determine if the use of written reading response activities would improve reading comprehension when students are reading independently. The study was conducted with twenty 3rd grade students. The students read one text a week for ten weeks and completed written reading response activities before, during, and after reading each text. The reading responses focused on the comprehension strategies of predicting, questioning, visualizing, and summarizing. The goal was for the students to build the metacognitive skill of comprehension monitoring and use the reading strategies when independently reading. Data was collected from teacher created rubrics from the reading responses, comprehension quizzes for each text read, and reading comprehension scores from the aimwebPlus Universal Screening assessment. Analysis of the data showed a positive effect size of the use of reading responses on reading comprehension when reading independently

    Introduction to Ecology

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    This Grants Collection for Introduction to Ecology was created under a Round Eight ALG Textbook Transformation Grant. Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process. Documents are in .pdf format, with a separate .docx (Word) version available for download. Each collection contains the following materials: Linked Syllabus Initial Proposal Final Reporthttps://oer.galileo.usg.edu/biology-collections/1019/thumbnail.jp

    Tidal disruption of NEAs - a case of P\v{r}\'ibram

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    This work studies the dynamical evolution of a possible meteor stream along the orbit of the P\v{r}\'{i}bram meteorite, which originated in the tidal disruption of the putative rubble-pile-like parent body during a close approach to the Earth. We assumed the disruption at the time when the ascending or descending node of the parent orbit was close to the Earth's orbit. In the last 5000 years, the P\v{r}\'{i}bram orbit has crossed the Earth orbit twice. It happened about 4200 years and 3300 years ago. In both cases, we modeled the release of particles from the simplified model of rotating asteroid, and traced their individual orbital evolution to the current date. It takes several hundred years to spread released meteoroids along the entire orbit of the parent body. Even today, the stream would be relatively narrow. Considering a model parent body with physical parameters of the asteroid Itokawa, the complete disintegration of the object produced 3.8×1011\times10^{11} meteoroid particles with diameter ≥\geq 1\,cm. The meteor activity observed from the Earth is revealed and justification of follow-up observation during suggested activity of the shower in the first two weeks of April is discussed. The Earth's tidal forces would disintegrate a fraction of NEA population into smaller objects. We evaluate the upper limit of mass of disintegrated asteroids within the mean NEA lifetime and the contribution of disrupted matter to the size distribution of the NEA.Comment: 8 pages, 10 figure

    Fragment properties at the catastrophic disruption threshold: The effect of the parent body's internal structure

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    Numerical simulations of asteroid break-ups, including both the fragmentation of the parent body and the gravitational interactions between the fragments, have allowed us to reproduce successfully the main properties of asteroid families formed in different regimes of impact energy, starting from a non-porous parent body. In this paper, using the same approach, we concentrate on a single regime of impact energy, the so-called catastrophic threshold usually designated by Q*D, which results in the escape of half of the target's mass. Thanks to our recent implementation of a model of fragmentation of porous materials, we can characterize Q*D for both porous and non-porous targets with a wide range of diameters. We can then analyze the potential influence of porosity on the value of Q*D, and by computing the gravitational phase of the collision in the gravity regime, we can characterize the collisional outcome in terms of the fragment size and ejection speed distributions, which are the main outcome properties used by collisional models to study the evolutions of the different populations of small bodies. We also check the dependency of Q*D on the impact speed of the projectile. In the strength regime, which corresponds to target sizes below a few hundreds of meters, we find that porous targets are more difficult to disrupt than non-porous ones. In the gravity regime, the outcome is controlled purely by gravity and porosity in the case of porous targets. In the case of non-porous targets, the outcome also depends on strength. We then propose some power-law relationships between Q*D and both target's size and impact speed that can be used in collisional evolution models.Comment: 18 pages, 19 Figures. Accepted for publication in Icaru

    Estimating Population Abundance with a Mixture of Physical Capture and PIT Tag Antenna Detection Data

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    The inclusion of passive interrogation antenna (PIA) detection data has promise to increase precision of population abundance estimates (Nˆ ). However, encounter probabilities are often higher for PIAs than for physical capture. If the difference is not accounted for, Nˆ may be biased. Using simulations, we estimated the magnitude of bias resulting from mixed capture and detection probabilities and evaluated potential solutions for removing the bias for closed capture models. Mixing physical capture and PIA detections (pdet) resulted in negative biases in Nˆ . However, using an individual covariate to model differences removed bias and improved precision. From a case study of fish making spawning migrations across a stream-wide PIA (pdet ≤ 0.9), the coefficient of variation (CV) of Nˆ declined 39%–82% when PIA data were included, and there was a dramatic reduction in time to detect a significant change in Nˆ . For a second case study, with modest pdet (≤0.2) using smaller PIAs, CV (Nˆ ) declined 4%–18%. Our method is applicable for estimating abundance for any situation where data are collected with methods having different capture–detection probabilities

    Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes

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    BACKGROUND: The agouti protein is a paracrine factor that is normally present in the skin of many species of mammals. Agouti regulates the switch between black and yellow hair pigmentation by signalling through the melanocortin 1 receptor (Mc1r) on melanocytes. Lethal yellow (A(y)) and viable yellow (A(vy)) are dominant regulatory mutations in the mouse agouti gene that cause the wild-type protein to be produced at abnormally high levels throughout the body. Mice harboring these mutations exhibit a pleiotropic syndrome characterized by yellow coat color, obesity, hyperglycemia, hyperinsulinemia, and increased susceptibility to hyperplasia and carcinogenesis in numerous tissues, including the liver. The goal of this research was to determine if ectopic expression of the agouti gene in the liver alone is sufficient to recapitulate any aspect of this syndrome. For this purpose, we generated lines of transgenic mice expressing high levels of agouti in the liver under the regulatory control of the albumin promoter. Expression levels of the agouti transgene in the liver were quantified by Northern blot analysis. Functional agouti protein in the liver of transgenic mice was assayed by its ability to inhibit binding of the α-melanocyte stimulating hormone (αMSH) to the Mc1r. Body weight, plasma insulin and blood glucose levels were analyzed in control and transgenic mice. Control and transgenic male mice were given a single intraperitoneal injection (10 mg/kg) of the hepatocellular carcinogen, diethylnitrosamine (DEN), at 15 days of age. Mice were euthanized at 36 or 40 weeks after DEN injection and the number of tumors per liver and total liver weights were recorded. RESULTS: The albumin-agouti transgene was expressed at high levels in the livers of mice and produced a functional agouti protein. Albumin-agouti transgenic mice had normal body weights and normal levels of blood glucose and plasma insulin, but responded to chemical initiation of the liver with an increased number of liver tumors compared to non-transgenic control mice. CONCLUSIONS: The data demonstrate that liver-specific expression of the agouti gene is not sufficient to induce obesity or diabetes, but, in the absence of these factors, agouti continues to promote hepatocellular carcinogenesis

    Structural characterization of ordered arrays of sn-glycerol-3-phosphate acyltransferase from Escherichia coli.

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    Overproduction of the sn-glycerol-3-phosphate acyltransferase in Escherichia coli leads to incorporation of this integral membrane protein into ordered tubular arrays within the cell. Freeze-fracture-etch shadowing was performed on suspensions of partially purified tubules and whole bacteria. This procedure revealed the presence of ridges and grooves defining a set of long-pitch left-handed helical ridges. The long-pitch helices represented chains of acyltransferase dimers. Tubules observed within the cell were often closely packed, with an apparent alignment of grooves and ridges in adjacent tubules. Fracture planes passing through the tubules indicated the presence of a bilayer structure, with some portion of the enzyme being associated with the membrane. The major portion of the enzyme extended from the hydrophilic surface, forming a large globular structure that, in favorable views, displayed a central cavity facing the cytoplasm. Computer analysis of shadowed tubules revealed that the left-handed helices were six stranded, with a pitch of 1,050 A (105.0 nm) and a spacing of 75 A (7.5 nm) between acyltransferase dimers along the chains. Analysis of the predicted secondary structure failed to reveal obvious transmembrane segments, suggesting that very little of the protein was inserted into the bilayer
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