O-GlcNAcylation and Activity of Succinate Dehydrogenase

Undergraduate Basi

Pyruvate

Undergraduate Applie

Lecane (Rotifera: Lecanidae) community in psammon habitat in Central Coast Vietnam: Diversity and relation to environmental condition

Characteristics of the Lecane (Rotifera) community in psammon in Central Coast Vietnam were investigated. A total of 50 taxa were identified in samples collected at hygropsammon zones of temporary pools, contributing 4 new species to rotifers' record of Vietnam. Psammonxenic species accounted for the largest percentage of Lecane community with 82%, followed by psammophiles (12%) and psammonbionts (6%). Influences of some environmental factors on the distribution of psammic lecanids were also observed. This group of organisms showed a slight tendency towards sand with grain sizes larger than 125 µm. Besides, other abiotic factors including pH, total phosphorus (TP) and total dissolved solids (TDS) were also found to significantly related to the distribution of some common Lecane species

Effectiveness of perindopril/amlodipine fixed-dose combination in the treatment of hypertension: a systematic review

Background: Uncontrolled blood pressure is a major risk factor for cardiovascular diseases. Fixed-dose combination (FDC) therapy offers a promising approach to addressing this challenge by providing a convenient single-tablet solution that enhances the effectiveness of blood pressure control. In our systematic review, we assess the effectiveness of perindopril/amlodipine FDC in managing blood pressure.Methods: We conducted a comprehensive search across four primary electronic databases, namely, PubMed, Virtual Health Library (VHL), Global Health Library (GHL), and Google Scholar, as of 8 February 2022. Additionally, we performed a manual search to find relevant articles. The quality of the selected articles was evaluated using the Study Quality Assessment Tools (SQAT) checklist from the National Institute of Health and the ROB2 tool from Cochrane.Results: Our systematic review included 17 eligible articles. The findings show that the use of perindopril/amlodipine FDC significantly lowers blood pressure and enhances the quality of blood pressure control. Compared to the comparison group, the perindopril/amlodipine combination tablet resulted in a higher rate of blood pressure response and normalization. Importantly, perindopril/amlodipine FDC contributes to improved patient adherence with minimal side effects. However, studies conducted to date have not provided assessments of the cost-effectiveness of perindopril/amlodipine FDC.Conclusion: In summary, our analysis confirms the effectiveness of perindopril/amlodipine FDC in lowering blood pressure, with combination therapy outperforming monotherapy and placebo. Although mild adverse reactions were observed in a small subset of participants, cost-effectiveness assessments for this treatment remain lacking in the literature

TextANIMAR: Text-based 3D Animal Fine-Grained Retrieval

3D object retrieval is an important yet challenging task, which has drawn more and more attention in recent years. While existing approaches have made strides in addressing this issue, they are often limited to restricted settings such as image and sketch queries, which are often unfriendly interactions for common users. In order to overcome these limitations, this paper presents a novel SHREC challenge track focusing on text-based fine-grained retrieval of 3D animal models. Unlike previous SHREC challenge tracks, the proposed task is considerably more challenging, requiring participants to develop innovative approaches to tackle the problem of text-based retrieval. Despite the increased difficulty, we believe that this task has the potential to drive useful applications in practice and facilitate more intuitive interactions with 3D objects. Five groups participated in our competition, submitting a total of 114 runs. While the results obtained in our competition are satisfactory, we note that the challenges presented by this task are far from being fully solved. As such, we provide insights into potential areas for future research and improvements. We believe that we can help push the boundaries of 3D object retrieval and facilitate more user-friendly interactions via vision-language technologies.Comment: arXiv admin note: text overlap with arXiv:2304.0573

Pharmacists’ Perspectives on the Use of Telepharmacy in Response to COVID-19 Pandemic in Ho Chi Minh City, Vietnam

Introduction: Telepharmacy, the application of information and communication technologies in healthcare services, has been adopted in many countries to provide patients with pharmaceutical care. However, it has yet to be widely used in Vietnam. This study was conducted to assess the current status of use and the factors associated with the willingness to use telepharmacy of pharmacists in Vietnam. Methods: A descriptive cross-sectional study was conducted from February to July 2021; 414 pharmacists were recruited to fill in an online survey. Results: Overall, 86.7% of participants have used telepharmacy application and 87.2% of them were willing to apply telepharmacy in pharmacy practice. According to our multivariate analysis, the level of readiness was associated with positive attitude (odds ratio [OR] = 4.67; 95% confidence interval [CI]: 2.26-9.66), and a good behavior (OR = 11.34; 95% CI: 3.84-33.45). Discussion: Developing a telepharmacy system with appropriate features is essential to meet the requirements of pharmacy practice amid the spread of the COVID-19 pandemic

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

Background Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population. Methods AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921. Findings Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months. Interpretation Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke

Management Strategies for Digital Transformation : thrive in constant change

Companies of all types and sizes in the dynamism and unpredictability of today’s marketplace, have been investing seriously with a big amount of money in the digitization of their business models, and operating in the modern business landscape are increasingly finding themselves managing numerous employees, customers, and products. Because of the rapid upheaval, many tech companies introduced their new technologies constantly, and appearances of new market opportunities and shifts in the way how their consumers choose, interact, and adopt the standards to their demand. Companies, therefore, were investing in the reimagining of their business models as a result of the changing consumer expectations. Digital transformations with technology, innovative potential in business models and processes, as well as formulation of more comprehensive strategies are playing an increasingly significant role in making a business more sustainable and more effective in the long term. This research paper associates an academic literature review with the Meta-synthesis approach developed by Hoon and tries to shed light on this interesting topic by accommodating academic and practical insights. And with those challenges and under pressure to change to achieve relevance in the new business landscape in the Fourth Industrial Revolution. Modern businesses should consider managing digital transformation in their management strategies and learn to adapt to new advancements simultaneously with innovating to stay ahead of the competition by adopting new digital technology convergence, such as Robotic Process Automation, Artificial Intelligence, Blockchain, Virtual Reality and Augmented Reality, etc. And the result will lead to the creation of a viable, safe, cost-efficient, and successful strategy as well as help businesses increasingly enhance more agile, lean, interactive, and customer-centricity. In general, 81 sample articles were collected from the four databases and after 6 research steps of the meta-synthesis method and step of comparative and analysis. The eventual result is to formulate the digital transformation strategies framework and contribute with a set of 15 strategies in 6 action fields. The contribution of this research suggests the management strategies by applying or associating them with their business based on the context of the company. As the result, companies can accomplish successfully face the challenges of digital transformation. This study is beneficial to company managers who want to find management strategies to successfully implement the digital transformation process in today’s business world of constant change

Employee-friendly practices and corporate financial performance: Evidence from a frontier market

This study investigates the association between employee-friendly schemes and firm financial performance using a frontier market, Vietnam, as a research context. We employ Anphabe's "Top 100 Vietnam Best Places to Work" lists to identify companies with ideal employee-friendly practices. Using a data sample of more than 3,800 firm-year observations, we document a strong and positive relationship between employee welfare and firm performance measured by Tobin's q. Our result is robust to a battery of sensitivity tests, including an alternative indicator of financial performance, alternative selection criteria, and different econometric techniques