10 research outputs found

    Nasal filter reveal exposure risks of inhalable particulates and heavy metals in urban women

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    Urban populations, especially women, are vunerable to exposure to airborne pollution, particularly inhalable particulates (PM10). Thus, more accurate measurement of PM10 levels and evaluating their health effects is critical for guiding policy to improve human health. Previous studies obtained personal PM10 with time-weighted average by air filter-based sampling (AFS), which ignores individual differences and behavioral patterns. Here, we used nasal filters instead of AFS to obtain actual inhaled PM10 under short-term exposure for urban dwelling women during a severe haze event in Beijing in 2016. The levels of six heavy metals such as As, Cd, Ni, Cr, Pb, and Co in PM10 were investigated, and carcinogenic and non-carcinogenic risks evaluated based on an adjusted US EPA health risk assessment model. The health endpoints for urban dwelling women were further assessed through an exposure-reponse model. We found that the hourly inhaled dose of PM10 obtained through the nasal filter was about 2.5–17.6 times that obtained by AFS, which also resulted in 4.41–11.30 times more morbidity than estimated by AFS (p 18.8 μg/kg·h) and heavy metals (>2.2 ng/kg·h), and these populations are therefore at greatest risk of developing non-cancer (HI = 4.16) and cancer (Rt = 7.8 × 10−3) related morbities

    City-level water withdrawal and scarcity accounts of China

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    In the context of China’s freshwater crisis high-resolution data are critical for sustainable water management and economic growth. Yet there is a dearth of data on water withdrawal and scarcity regardless of whether total or subsector amount, for prefectural cities. In administrative and territorial scope, we accounted for water withdrawal of all 63 economic-socio-environmental sectors for all 343 prefectural cities in China, based on a general framework and 2015 data. Spatial and economic-sector resolution is improved compared with previous studies by partitioning general sectors into industrial and agricultural sub-sectors. Construction of these datasets was based on selection of 16 driving forces. We connected a size indicator with corresponding water-withdrawal efficiency. We further accounted for total blue-water withdrawal and quantitative water scarcity status. Then we compared different scopes and methods of official accounts and statistics from various water datasets. These disaggregated and complete data could be used in input-output models for municipal design and governmental planning to help gain in-depth insights into subsector water-saving priorities from local economic activities

    The lateral meniscus as a guide to anatomical tibial tunnel placement during anterior cruciate ligament reconstruction

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    Purpose: The aim of the study is to show, on an MRI scan, that the posterior border of the anterior horn of the lateral meniscus (AHLM) could guide tibial tunnel position in the sagittal plane and provide anatomical graft position. Method: One hundred MRI scans were analysed with normal cruciate ligaments and no evidence of meniscal injury. We measured the distance between the posterior border of the AHLM and the midpoint of the ACL by superimposing sagittal images. Results: The mean distance between the posterior border of the AHLM and the ACL midpoint was -0.1mm (i.e. 0.1mm posterior to the ACL midpoint). The range was 5mm to -4.6mm. The median value was 0.0mm. 95% confidence interval was from -0.5 to 0.3mm. A normal, parametric distribution was observed and Intra- and inter-observer variability showed significant correlation (p<0.05) using Pearsons Correlation test (intra-observer) and Interclass correlation (inter-observer). Conclusion: Using the posterior border of the AHLM is a reproducible and anatomical marker for the midpoint of the ACL footprint in the majority of cases. It can be used intra-operatively as a guide for tibial tunnel insertion and graft placement allowing anatomical reconstruction. There will inevitably be some anatomical variation. Pre-operative MRI assessment of the relationship between AHLM and ACL footprint is advised to improve surgical planning.The article is available via Open Access.Published (Open Access

    Index decomposition analysis of urban crop water footprint

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    Rapid urbanization has resulted in often unplanned increases in population, and food demand in cities. Historically, hinterlands to these cities have acted as breadbaskets producing food to the urban residents. Accordingly, a large amount of available freshwater has been needed to support these croplands. However, the rapid expansion of cities in developing countries has significantly changed both the croplands around cities and the water demand. It is thus important to quantitatively investigate the water-food nexus of cities related to the changing hinterland agriculture. Water footprint is an indicator reflecting the human impact on water. In this study, we quantified both the blue and green water footprint of major crop products in Suzhou city, China using a bottom-up accounting method. A novel decomposition analysis was carried out with a Logarithmic Mean Divisia Index (LMDI) method to study the driving forces that changed the water footprint during the period 2001-2010. The drivers were designed to reflect the factors related to farmland, such as yield and crop area. This is different from previous decomposition analyses, which focused on economic factors such as GDP. The results show that the crop water footprint of Suzhou city has seen a general decreasing trend between 2001 and 2010. The decomposition analysis showed that the decline of crop area was the main driver that decreased the crop water footprint, followed by the virtual water content (water consumption per unit of production). In contrast the changes of crop combination and yield contributed to an increase in the crop water footprint. Although the shrink of urban croplands decreased the water footprint of crop products. Cities’ increasing demand for food will increase the crop water footprint of consumption. This will increase the dependence of cities on external water footprint of crop products (water embodied in imported crops), which may impact upon food security in cities in the long term

    Revealing Trade Potential for Reversing Regional Freshwater Boundary Exceedance

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    Applying the planetary boundary for the freshwater framework at the regional level is important in supporting local water management but is subject to substantial uncertainty. Previous estimates have not fully investigated the potential of trade in mitigating regional freshwater boundary (RFB) exceedance. Here, we estimate RFB based on the average results of 15 different hydrological models to reduce uncertainty. We then propose a framework to divide the RFB exceedance/maintenance into contributions from both consumption and trade and further identify trade contribution into six types. We applied the framework to China’s provinces, which are characterized by intensive interprovincial trade and a significant mismatch in water resource supply and demand. We found that the current trade pattern limits the role of trade to mitigate RFB exceedance. For the importing provinces exceeding RFBs, 78% of their imported goods and services came from other RFB exceeding provinces. Scenario analysis showed that relying on increased imports alone, even to its greatest extent, will not reverse RFB exceedance in most importing provinces. Increased imports, however, will have an aggregate effect on the trade partners, leading to the exceedance of the national freshwater boundary. We also found that promoting export of goods and services from non-RFB exceeding provinces and reducing their water intensity will help address the imbalance both locally and, in the aggregate, nationally

    Host Defence Cryptides from Human Apolipoproteins: Applications in Medicinal Chemistry

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