Eksperimen Pendekatan Scientific Terintegrasi Pada Metode Discovery Learning Pada Pembelajaran Matematika Ditinjau Dari Kemandirian Belajar (Pada Siswa kelas X Semester Genap SMK Muhammadiyah 3 Surakarta Tahun Ajaran 2014/2015)

The Objectives of the Research are, (1) the Differences result of mathematic learning concerning on the scientific method, its integrating on the discovery learning and conventional method, (2) the Differences result of mathematic learningby observation on the self-determining study, (3) the interaction between learning method and the self-determining study concerning onthe students' result of mathematic learning. The population of this study is grade tenth Vocational High School Muhammadiyah 3 Surakarta in the semester II academic year 2014/2015.The sample in this study consisted of grade tenth TIPTL as the experimental class and class X TKJ as the control class. The sampling technique is by using random sampling method. The data collection Methods is by using the test method, questionnaire method, and methods of documentation. The data analysis techniques is by using two-way analysis of variance test with different cells, previously tested using analysis prerequisite Lilifors method to test for normality and the homogeneity test method for the Bartlet.From the results of the data analysis with a significance level of 5% is obtained: (1) there is differentiation of discovery learning methods and conventional learning on learning outcom s of mathematics with Fa = 5.44, (2) there is variance of the result of studies terminology by self-determining learning mathematic with Fb = 4, 66 and (3) there is no interaction between teaching methods and the self-determining learning mathematic by the students' with Fab = 0.50

The Influence of Low HLA-G Protein Expression on Hsp-70 and VCAM-1 Profile in Preeclampsia

Objective: To analyze HLA-G, Hsp-70, and VCAM-1 proteins expression on trophoblast in women with preeclampsia and women with normal pregnancy, and to assess causality relationship between low HLA-G expression and the increased Hsp-70 and VCAM-1 expression in preeclampsia. Method: Observational analytic study with cross sectional design. Results: Trophoblastic HLA-G expression in pregnant women with preeclampsia is lower (p = 0.01) than its expression in women with normal pregnancy. The expressions of Hsp-70 (p = 0.02) and VCAM-1 (p = 0.00) in preeclampsia are higher, compared to normal pregnancy. Regression analysis showed that low HLA-G is a predictor for the increase of trophoblastic Hsp-70 and VCAM-1. Conclusion: Low trophoblastic HLA-G in is a predictor for endothelial dysfunction in women with preeclampsia. [Indones J Obstet Gynecol 2010; 34-4: 185-90] Keywords: preeclampsia, HLA-G, Hsp-70, VCAM-1, endothelial dysfunctio

Pengaruh Program Insentif dan Pelatihan Kerja terhadap Kinerja Karyawan

This Research to know and analyse employees performance in Terra of Computer System Kediri. Variable in this research is incentive and training of job/activity as variable of X, and employees performance as variable Y. Research method the used is technique method analyse descriptive data. While sampel in this research that is employees of Terra Computer System Kediri amounting to 25 people. How employees can work with as good as possible in finishing work with existence of gift/ giving of incentive and training of job/activity. This research aim to to show influence of incentive and training of job/activity to employees performance. In analysing data used by validity test, test reliabilitas, doubled linear regression analysis, test of F, test T, and test of determinasi. In this research show R niai equal to 0,645 with the meaning relation or correlation between independent variable consisting of incentive ( X1), training of job ( X2) with variable of dependen employees performance ( Y) have high relation or very strong. Assess R Square show 0,416, this means that influence of independent variable consisting of incentive ( X1), training of job ( X2) to variable of dependen employees performance ( Y) is 41,6% while 58,4% influenced by other factor

Low Class Ib (HLA-G/Qa-2) MHC Protein Expression against Hsp-70 and VCAM-1 Profile on Preeclampsia. An observation on experimental animal Mus Musculus with Endothelial Dysfunction model

Objective: To analyze the expression of MHC class Ib Qa-2 protein (homologue to HLA-G in human), Hsp-70, and VCAM-1 in trophoblast cells of preeclampsia and control using endothelial dysfunction model on Mus Musculus. Method: Design of study is experimental study. Pregnant mice was treated with anti-Qa-2. Hsp-70 and VCAM-1 expressions of trophoblast cells was assessed on week I, II, and III. Result: Negative Qa-2 expression was achieved after administration of 40ng anti Qa-2 on the fifth day of pregnancy. The Hsp-70 and VCAM-1 expressions in negative Qa-2 mice (preeclampsia) was higher compared with those of positive Qa-2 mice (normal pregnancy) on week I, II and III. Conclusion: Low Qa-2 and high of HSP-70 and VCAM-1 expression might be useful for prediction of preeclampsia or endothelial dysfunction. [Indones J Obstet Gynecol 2010; 34-3: 103-7] Keywords: preeclampsia, HLA-G/Qa-2, Hsp-70, VCAM-1, endothelial dysfunctio

GCG, CORPORATE CHARACTERISTICS, AND FINANCIAL DISTRESS AS A DETERMINANT OF EXTENSIVE VOLUNTARY DISCLOSURES

The existence of a conflict of interest between the principal and theagent causes information asymmetry. This information asymmetry canbe minimized by voluntary disclosure in the annual report. GCGfactors, company characteristics, and financial distress are predicted toinfluence the extensive voluntary disclosure. This study aims to examinethe effect of ownership dispersion, financial distress, the board size,CEO duality and age of listings on the extensive voluntary disclosure.Data population are basic and chemical industry companies listed onIDX for the 2015-2018. A purposive sampling was used as method andobtained 160 samples. This study used secondary data from annualreports. Data were analyzed by using the Multiple Linear RegressionAnalysis method. This study found that Ownership Dispersion and Sizeof the Board of Commissioners have a significant positive effect onExtensive Voluntary Disclosure. Whereas Financial Distress, CEODuality, and Age of Listing have no significant effect on ExtensiveVoluntary Disclosure

The effect of L-arginine therapy on hepatocyte cells damage in mice (Mus musculus) model of preeclampsia

Preeclampsia is one of the main contributors on morbidity and mortality of mother and fetus. Imbalance of body antioxidants and oxidants has a role on endothelial destruction causing endothelial dysfunction which leads to preeclampsia. L-arginine administration is indicated to be able to fix the remodelling process of hepatocytes which was damaged on preeclampsia. The aim of this study was to investigate the effect of L-arginine on hepatocyte cells damage on mouse (Mus musculus) model of preeclampsia. Experimental study was conducted in the Experimental Animal Warehouse and Biomedical Laboratory, Faculty of Veterinary Medicine, Airlangga University, Surabaya. A total of 30 pregnant mice were divided into three groups with 10 mice in each group i.e. normal, preeclampsia model and preeclampsia model with L-arginine therapy pregnant mice. Preparates were taken from dissected mice liver, with prior paraffin block and were then stained with hematoxylin-eosin. Results were analyzed semi quantitatively with Manja Roenigk hepar histology scoring method. Data were analyzed using Kruskal-Wallis and Man-Whitney test. Mean of hepar histopathology score of preeclampsia model with L-arginine therapy (40.80±1.17/µm2) was significantly lower compared with preeclampsia model pregnant mice (58.80±4.23/µm2) (p<0.05), however it was significantly higher compared with normal pregnant mice (18.40±2.41/µm2) (p<0.05). It was indicated that the L-arginine therapy on preeclampsia mouse model can reduce the score of hepar histopathology. In conclusion, L-arginine administration can reduce the hepatocyte cells damage of mouse due to preeclampsia

Hubungan Asupan Energi Protein dan Kepatuhan Minum Obat dengan Status Gizi Pasien TB Paru di Klinik DOTS RSUD. Dr. R. Soeprapto Cepu

Latar Belakang: Penyakit tuberkulosis paru merupakan masalah kesehatan yang perlu ditangani dengan baik karena tingkat kematian dan morbiditas yang tinggi. Salah satu upaya untuk mencegah tuberkulosis paru adalah pengobatan yang teratur dan meningkatkan status gizi yang optimal.Tujuan : Penelitian ini bertujuan untuk mengetahui korelasi dari kepatuhan gizi dan asupan obat dengan status gizi pasien TB paru, karena berdasarkan survey pendahuluan pada 10 pasien dengan TB paru di klinik DOTS RSUD. dr. R. Soeprapto Cepu memiliki status malnutrisi dengan Indeks Massa Tubuh (IMT) 16,075 kg / m2.Metode: Penelitian ini menggunakan deskriptif korelasi dengan rancangan cross sectional. Pengumpulan data menggunakan kuesioner dan metode recall 3x24 jam pada 70 pasien dengan TB paru di klinik DOTS sebagai subyek penelitian.Hasil: Hasil analisis dengan uji chi-square antara asupan energi, asupan protein, dan kepatuhan obat dengan status gizi menunjukkan nilaip 0,05 sehingga terdapat hubungan yang signifikan antara variabel.Kesimpulan : Ada hubungan antara asupan protein energi dan kepatuhan obat dengan status gizi pasien TB paru

PENGARUH ANTISEPTIK HERBAL BAWANG DAYAK (Eleutherine palmifolia L. Merr) SEBAGAI TEAT DIPPING TERHADAP JUMLAH MIKROBA DAN pH SUSU KAMBING SAANEN

Tujuan penelitian untuk mengetahui pengaruh antiseptik herbal bawang dayak sebagai teat dipping terhadap jumlah mikroba dan pH susu Kambing Saanen. Materi yang digunakan  12 ekor Kambing Saanen umur 3, 4 dan 5 tahun, antiseptik kimia (Iodium 5%), Bawang Dayak, aquades, Plate Count Agar (PCA), larutan buffer pH 4 dan 9. Metode penelitian menggunakan metode percobaan, dengan menggunakan Rancangan Acak Kelompok (RAK). Ada 4 perlakuan dan 3 kelompok. Perlakuan adalah P0 = Teat dipping antiseptik kimia (Iodium 5%), P = Teat dipping antiseptik herbal bawang dayak konsentrasi 10%, P2= konsentrasi 20%, P3= konsentrasi 30%. Variabel yang diamati meliputi total bakteri dan pH. Data yang telah diperoleh dianalisis ragam (ANOVA). apabila hasilnya menunjukkan pengaruh nyata atau sangat nyata pada perlakuan, maka dilanjutkan Uji Beda Nyata Terkecil (BNT). Hasil penelitian menunjukkan bahwa antiseptik herbal Bawang Dayak sebagai teat dipping pada hari ke-7 berpengaruh sangat nyata (P0,05) terhadap pH susu Kambing Saanen dengan rata- rata nilai pH pada hari ke-7 diperoleh rataan nilai pH sebesar P0=6,4, P1=6,4, P2=6,4, P3=6,7, Pada hari ke-14 diperoleh rataan sebesar P0=6,7, P1=6,5, P2=6,4, P3=6,7.Kata Kunci: bawang dayak, susu kambing saanen, teat dipping, total bakteri, pH

Risk Factors of Maternal Death in Karanganyar, Central Java, Indonesia

Background: The maternal mortality rate is an indicator of national health status. To reduce the Maternal Mortality Rate (MMR), especially in Karanganyar Regency, the risk factors that affect maternal mortality must be known.Subjects and Method:  This was a case-control study conducted in Karanganyar, Central Java, from 2016 to 2017. A sample of 57 study subjects was selected by fixed disease sampling. The dependent variable was maternal mor­tality. The independent variables were pregnancy complica­tions, labor complications, post­partum complications, maternal age, a distance of pregnancy, parity, maternal nutritional status during pregnancy, number of antenatal care visits, delay in making decisions, late referrals, late handling of staff, maternal education, maternal work, and income family. Data collected using questionnaires were then analyzed using bivariate analysis and multivariate analysis.Results: Maternal mortality was affected by pregnancy complications (OR= 6.98; 95% CI= 2.06 to 23.71; p= 0.001), labor complication (OR= 7.59; 95% CI= 2.19 to 26.28; p= 0.001), delayed labor (OR = 5.39; 95% CI= 1.17 to 24.75; p= 0.021), and family income (OR= 4.29; 95% CI= 1.28 to 14.41; p = 0.015).Conclusion: Maternal mortality was affected by pregnancy complications, labor complication, delayed labor, and family income.Keywords: risk factors, maternal mortality, Karanganyar RegencyCorrespondence: Noferi Kusnadi. Department of Obstetrics and Gynecology, Dr. Moewardi Hospital/ Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java. Mobile: 08112654789. Email: [email protected] of Maternal and Child Health (2019), 4(6): 499-506https://doi.org/10.26911/thejmch.2019.04.06.10