14 research outputs found
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.
Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist
Apollonia d’Illyrie (Albanie) - La ville haute : fouille du grand portique
Consultable sur (http://cefr.revues.org/1102).International audienc
Gërmimet në portikun e madh dhe në agoranë e qytetit të sipërm Apoloni 2012
International audienc
Nouvelles données sur l'urbanisme et l'histoire de la ville antique.: I. La ville haute
International audienc
Activités archéologiques de l'Ecole française de Rome.: Chronique, année 2009. Apollonia d'Illyrie (Albanie)
International audienc