131 research outputs found

    Maths Express au carrefour des cultures

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    International audienceCette brochure a été réalisée à l'occasion de la quinzième édition du Salon Culture et Jeux mathématiques. Elle a pour objectif de montrer que les mathématiques sont au coeur de toutes les activités humaines qu'elles soient sociales, techniques, scientifiques, artistiques ou ludiques. Elles sont nées et se sont développées au rythme des sociétés humaines

    Insights about saproxylic biodiversity living in old-growth forests of French Pyrénées

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    The symposium will span over four days, including a one day field trip. Keynote addresses will introduce morning sessions followed by parallel conference sessions. Scientific poster sessions, held in the late afternoon, will be combined with a cocktail buffet. A banquet will take place on Wednesday night. All events will be held at the Rouyn-Noranda Congress Center

    Real-life experience with ceftolozane/tazobactam in Canada: results from the CLEAR (Canadian LEadership on Antimicrobial Real-life usage) registry.

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    Objectives Ceftolozane/tazobactam is a cephalosporin/β-lactamase inhibitor combination with activity against Gram-negative bacilli. We report the use of ceftolozane/tazobactam in Canada using a national registry. Methods The CLEAR registry uses REDCapTM (Research Electronic Data Capture) (online survey, https://is.gd/CLEAR_ceftolozanetazobactam) to capture details associated with clinical use of ceftolozane/tazobactam. Results Data from 51 patients treated in 2020 with ceftolozane/tazobactam are available. Infections treated included hospital-acquired bacterial pneumonia (37.3% of patients), ventilator-associated bacterial pneumonia (15.7%), bone/joint infection (11.8%), complicated intra-abdominal infection (7.8%) and complicated skin and skin structure infection (7.8%). 17.6% of patients had bacteremia and 47.1% were in intensive care. Ceftolozane/tazobactam was primarily used as directed therapy for Pseudomonas aeruginosa infections (92.2% of patients). Ceftolozane/tazobactam was used because of resistance to (86.3%), failure of (11.7%), or adverse effects from (2.0%) previously prescribed antimicrobials. Ceftolozane/tazobactam susceptibility testing was performed on isolates from 88.2% of patients. Ceftolozane/tazobactam was used in combination with another antimicrobial active versus Gram-negative bacilli in 39.2% of patients (aminoglycosides [15.7%], fluoroquinolones [7.8%] and colistin/polymyxin B [7.8%]). The dosage regimen was customized in all patients based on their creatinine clearance. Treatment duration was primarily >10 days (60.8% of patients) with microbiological success in 60.5% and clinical success in 64.4% of patients. 7.8% of patients had adverse effects not requiring drug discontinuation. Conclusions In Canada, ceftolozane/tazobactam is used as directed therapy to treat a variety of severe infections caused MDR P. aeruginosa. It is commonly used in combination with other antimicrobials with relatively high microbiological/clinical cure rates, and an excellent safety profile

    Inventaire et évaluation des vieilles forêts des Pyrénées de Midi-Pyrénées

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    Les 11, 12 et 13 février 2016, ce sont déroulées les 5e Rencontres Naturalistes de Midi-Pyrénées dans le Gers, à Auch. Tous les 3 ans, ce rendez-vous incontournable des amateurs et professionnels de la biodiversité de Midi-Pyrénées et d’ailleurs, a rassemblé plus de 600 participants sur les 3 jours. Le succès de cet événement n’aurait pas été aussi complet sans l’aide des bénévoles et des associations partenaires. Les 5e Rencontres Naturalistes se sont ouvertes sur les discours de Nadia Baïtiche-Moine, Adjointe au Maire d’Auch, de Jérôme Calas, Président de Nature Midi-Pyrénées et de Ronny Guardia-Mazzoleni, Conseiller régional Languedoc-Roussillon-Midi-Pyrénées. Au cours de ces 3 jours, ce sont près de 35 communications sur la faune, la flore et les espaces naturels, agricoles et forestiers qui ont été présentées : une véritable synthèse des différents travaux menés en Midi-Pyrénées depuis 3 ans dans le domaine de la connaissance et de la préservation de notre riche patrimoine naturel régional. Les nombreux participants d’horizons divers (associations, conservatoires, services de l’Etat, laboratoires de recherche, établissements scolaires, PNR ou collectivités) ont eu également l’occasion de profiter des temps de pause pour échanger autour d’une vingtaine de posters scientifiques et de différentes expositions

    Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

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    Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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