2,315 research outputs found
Un enfoque teórico para el abordaje de temas complejos en el aula : el caso de la alimentación humana
La propuesta que se presenta forma parte de los resultados y conclusiones de una investigación sobre los modelos de conocimiento científico escolar de un grupo de docentes sobre la alimentación humana (Bahamonde, 2007). Para caracterizar dichos modelos se elaboró una construcción teórica específica que incluye una propuesta de elementos de referencia para la construcción de islotes interdisciplinarios de racionalidad, en el marco de la ciencia escolar, revisitando la idea de Fourez (1997). Se trata de un recorte curricular multirreferenciado, que permita hacer frente a la complejidad de los aprendizajes vinculados a la salud o al ambiente. Para la construcción de los islotes o modelos teóricos ad hoc se desarrolla el ejemplo de la alimentación humana
A multivariate regional test for detection of trends in extreme rainfall: the case of extreme daily rainfall in the French Mediterranean area
In this paper we present a multivariate regional test we developed for the
detection of trends in extreme rainfall, which takes into account the
spatial dependence between rainfall measurements with copula functions. The
test is based on four steps. It was applied to a set of 92 series of Annual
Daily Maxima (ADM) rainfall in the French Mediterranean area, sampled during
the 1949–2004 observation period. The results show a low significant trend,
concerning mainly the mountains area in the west part of the French
Mediterranean region. The position's parameters of the ADM rainfall
probability distribution functions present a low but significant increasing
trend of about 5% to 10%, the same increase as that observed in ADM
rainfall quantiles in the last 56 years. Further work is needed
to understand if this significative trend is related to the global climate
change or to the natural variability of Mediterranean climate
A high resolution free surface model of the Mediterranean Sea
International audienceThis study describes a new model implementation for the Mediterranean Sea which has the presently highest vertical resolution over the Mediterranean basin. The resolution is of 1/16°×1/16° in horizontal and 71 unevenly spaced vertical levels. This model has been developed in the frame of the EU-MFSTEP project and it is the operational forecast model presently used at the basin scale. For the first time in the Mediterranean, the model considers an implicit free surface and this characteristics enhances the model capability to simulate the sea surface height variability. In this study we show the calibration/validation experiments done before and after the model has been used for forecasting. The first experiment consist of six years of a simulation forced by a perpetual year forcing and the other experiment is a simulation from January 1997 to December 2004, forcing the model with 6 h atmospheric forcing fields from ECMWF. For the first time the model Sea Level Anomaly is compared with SLA and with ARGO data to provide evidence of the quality of the simulation. The results show that this model is capable to reproduce most of the variability of the general circulation in the Mediterranean Sea even if some basic model inadequacies stand out and should be corrected in the near future
Rotational positioning of the tibial tray in total knee arthroplasty: A CT evaluation
SummaryIntroductionVarious surgical techniques have been described to set the rotational alignment of the tibial baseplate during total knee arthroplasty. The self-positioning method (“self-adjustment”) aligns the tibial implant according to the rotational alignment of the femoral component which is used as a reference after performing repeated knee flexion/extension cycles. Postoperative computed tomography scanning produces accurate measurements of the tibial baseplate rotational alignment with respect to the femoral component.HypothesisThe rotational positioning of the tibial baseplate matches the rotation of the femoral component with parallel alignment to the prosthetic posterior bicondylar axis.Patients and methodsA 3-month follow-up CT scan was carried out after primary total knee arthroplasty implanted in osteoarthritic patients with a mean 7.8° varus deformity of the knee in 50 cases and a mean 8.7° valgus deformity of the knee in 44 cases. The NexGen LPS Flex (Zimmer) fixed-bearing knee prosthesis was used in all cases. An independant examiner (not part of the operating team) measured different variables: the angle between the anatomic transepicondylar axis and the posterior bicondylar axis of the femoral prosthesis (prosthetic posterior condylar angle), the angle between the posterior bicondylar axis and the posterior marginal axis of the tibial prosthesis, the angle between the posterior marginal axis of the tibial prosthesis and the posterior marginal axis of the tibial bone and finally the angle between the anatomic transepicondylar axis and the posterior marginal axis of the tibial prosthesis.ResultsFor the genu varum and genu valgum subgroups, the mean posterior condylar axis of the femoral prosthesis was 3.1° (SD: 1.91; extremes 0° to 17.5°) and 4.7° (SD: 2.7; extremes 0° to 11°) respectively. The tibial baseplate was placed in external rotation with respect to the femoral component: 0.7° (SD : 4.45; extremes –9.5° to 9.8°) and 0.9° (SD: 4.53; extremes –10.8° to 9.5°), but also to the native tibia: 6.1° (SD: 5.85; extremes –4.6° to 22.5°) and 12.5° (SD: 8.6; extremes –10° to 28.9°). The tibial component was placed in internal rotation relative to the anatomic transepicondylar axis: 1.9° (SD : 4.93; extremes –13.6° to 7°) and 3° (SD : 4.38; extremes –16.2° to 4.8°).DiscussionThe tibial component is aligned parallel to the femoral component whatever the initial frontal deformity (P≅0.7). However, a difference was observed between the rotational alignment of the tibial baseplate and the native tibia depending on the initial deformity and could be attributed to the morphological variations of the bony tibial plateau in case of genu valgum.ConclusionThe self-positioning method is a reproducible option when using this type of implant since it allows the tibial component to be positioned parallel to the posterior border of the femur.Level of evidenceLevel III. Observational prospective study
Schmallenberg virus detection in Culicoides biting midges in Spain: First laboratory evidence for highly efficient infection of Culicoides of the Obsoletus complex and Culicoides imicola
Since Schmallenberg disease was discovered in 2011, the disease rapidly spread across Europe. Culicoides biting midges have been implicated as putative Schmallenberg vectors in Europe. The detection of Schmallenberg virus (SBV) in field collected Culicoides was evaluated through retrospective (2011–2012) collections and captures performed in 2013. This study represents the first detection of SBV in field collected Culicoides in Spain. Infectious midges were detected at the foothills of Pyrenees, Aramunt, in the summer 2012. All the specimens infected with Schmallenberg were of the species Culicoides obsoletus s.s. confirming its putative vector status in Spain. Experimental infection on field collected Culicoides provided evidence of atypical high efficiency for SBV vector infection and transmission potential in local populations of Culicoides imicola and in Culicoides of the Obsoletus complex. However, captured individuals of C. imicola were more susceptible to SBV infection than C. obsoletus s.l. (p < .001), with an infection ratio of 0.94 and 0.63, respectively. In contrast, a Culicoides nubeculosus colony appeared to be refractory to SBV infection.info:eu-repo/semantics/acceptedVersio
Impact of Multi-altimeter Sea Level Assimilation in the Mediterranean Forecasting Model
In this paper we analyze the impact of multi-satellite altimeter observations assimilation in a
high-resolution Mediterranean model. Four different altimeter missions (Jason-1, Envisat,
Topex/Poseidon interleaved and Geosat Follow-On) are used over a 7-month period [September
2004, March 2005] to study the impact of the assimilation of one to four satellites on the analyses
quality. The study highlights three important results. First, it shows the positive impact of the
altimeter data on the analyses. The corrected fields capture missing structures of the circulation and
eddies are modified in shape, position and intensity with respect to the model simulation. Secondly,
the study demonstrates the improvement in the analyses induced by each satellite. The impact of the
addition of a second satellite is almost equivalent to the improvement given by the introduction of
the first satellite: the second satellite data brings a 12% reduction of the root mean square of the
differences between analyses and observations for the Sea Level Anomaly (SLA). The third and
fourth satellite also significantly improve the rms, with more than 3% reduction for each of them.
Finally, it is shown that Envisat and Geosat Follow-On additions to J1 impact the analyses more
than the addition of Topex/Poseidon suggesting that the across track spatial resolution is still one of
the important aspects of a multi-mission satellite observing system. This result could support the
concept of multi-mission altimetric monitoring done by complementary horizontal resolution
satellite orbits
Diamond forms during low pressure serpentinisation of oceanic lithosphere
Diamond is commonly regarded as an indicator of ultra-high pressure conditions in
Earth System Science. This canonical view is challenged by recent data and interpretations
that suggest metastable growth of diamond in low pressure environments.
One such environment is serpentinisation of oceanic lithosphere, which produces
highly reduced CH4-bearing fluids after olivine alteration by reaction with infiltrating
fluids. Here we report the first ever observed in situ diamond within olivine-hosted,
CH4-rich fluid inclusions from low pressure oceanic gabbro and chromitite samples
from the Moa-Baracoa ophiolitic massif, eastern Cuba. Diamond is encapsulated in
voids below the polished mineral surface forming a typical serpentinisation array,
with methane, serpentine and magnetite, providing definitive evidence for its metastable
growth upon low temperature and low pressure alteration of oceanic lithosphere
and super-reduction of infiltrated fluids. Thermodynamic modelling of the observed solid and fluid assemblage at
a reference P-T point appropriate for serpentinisation (350 °C and 100 MPa) is consistent with extreme reduction of the fluid
to logfO2 (MPa) = −45.3 (ΔlogfO2[Iron-Magnetite] = −6.5). These findings imply that the formation of metastable diamond at
low pressure in serpentinised olivine is a widespread process in modern and ancient oceanic lithosphere, questioning
a generalised ultra-high pressure origin for ophiolitic diamond.European Union (EU)Spanish Projects
CGL2015-65824
RTI2018-099157-A-I00
PID2019-105625RB-C21
A.RNM.186.UGR18Spanish Government
RYC-2015-17596Mexican research program CONACYT-Ciencia Basica
A1-S-14574Mexican research program UNAM-PAPIIT
IA-10141
The Effect of Ongoing Exposure Dynamics in Dose Response Relationships
Characterizing infectivity as a function of pathogen dose is integral to
microbial risk assessment. Dose-response experiments usually administer doses to
subjects at one time. Phenomenological models of the resulting data, such as the
exponential and the Beta-Poisson models, ignore dose timing and assume
independent risks from each pathogen. Real world exposure to pathogens, however,
is a sequence of discrete events where concurrent or prior pathogen arrival
affects the capacity of immune effectors to engage and kill newly arriving
pathogens. We model immune effector and pathogen interactions during the period
before infection becomes established in order to capture the dynamics generating
dose timing effects. Model analysis reveals an inverse relationship between the
time over which exposures accumulate and the risk of infection. Data from one
time dose experiments will thus overestimate per pathogen infection risks of
real world exposures. For instance, fitting our model to one time dosing data
reveals a risk of 0.66 from 313 Cryptosporidium parvum
pathogens. When the temporal exposure window is increased 100-fold using the
same parameters fitted by our model to the one time dose data, the risk of
infection is reduced to 0.09. Confirmation of this risk prediction requires data
from experiments administering doses with different timings. Our model
demonstrates that dose timing could markedly alter the risks generated by
airborne versus fomite transmitted pathogens
Performance and security improvements in auv surveys using RF modules
Autonomous Platforms Department of Marine Technology Unit (UTMCSIC)
owns two portable AUV with water quality and imaging configurations that
at the moment only have been used in littoral waters for safety reasons. To be able
to operate this vehicles further off shore or out of line of sight and improve overall
safety this department is developing a RF system to localize this vehicles were GPRS
coverage is not available.Peer Reviewe
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