Teaching Information Fluency: How to Teach Students to be Efficient, Ethical, and Critical Information Consumers

Searching is becoming easier than thinking. Enter a query in a search engine, and the searcher is instantly flooded with results. Information has never been easier to retrieve and consume. At the same time, determining the quality of the results remains a daunting task. Despite the attempts to make search tools brain dead easy 1 to use, searching that reduces the need to think invites problems. Machines cannot reliably predict what each individual is hunting for, machines cannot determine what is credible, yet that is the direction search engine development is headed

On Motion Mechanisms of Freight Train Suspension Systems

In this dissertation, a freight train suspension system is presented for all possible types of motion. The suspension system experiences impacts and friction between wedges and bolster. The impacts cause the chatter motions between wedges and bolster, and the friction will cause the stick and non-stick motions between wedges and bolster. Due to the wedge effect, the suspension system may become stuck and not move, which cause the suspension lose functions. To discuss such phenomena in the freight train suspension systems, the theory of discontinuous dynamical systems is used, and the motion mechanism of impacting chatter with stick and stuck is discussed. The analytical conditions for the onset and vanishing of stick motions between the wedges and bolster are presented, and the condition for maintaining stick motion was achieved as well. The analytical conditions for stuck motion are developed to determine the onset and vanishing conditions for stuck motion. Analytical prediction of periodic motions relative to impacting chatter with stick and stuck motions in train suspension is performed through the mapping dynamics. The corresponding analyses of local stability and bifurcation are carried out, and the grazing and stick conditions are used to determine periodic motions. Numerical simulations are to illustrate periodic motions of stick and stuck motions. Finally, from field testing data, the effects of wedge angle on the motions of the suspension is presented to find a more desirable suspension response for design

CT Automated Exposure Control Using A Generalized Detectability Index

Purpose Identifying an appropriate tube current setting can be challenging when using iterative reconstruction due to the varying relationship between spatial resolution, contrast, noise, and dose across different algorithms. This study developed and investigated the application of a generalized detectability index (d\u27gen) to determine the noise parameter to input to existing automated exposure control (AEC) systems to provide consistent image quality (IQ) across different reconstruction approaches. Methods This study proposes a task‐based automated exposure control (AEC) method using a generalized detectability index (d\u27gen). The proposed method leverages existing AEC methods that are based on a prescribed noise level. The generalized d\u27gen metric is calculated using lookup tables of task‐based modulation transfer function (MTF) and noise power spectrum (NPS). To generate the lookup tables, the American College of Radiology CT accreditation phantom was scanned on a multidetector CT scanner (Revolution CT, GE Healthcare) at 120 kV and tube current varied manually from 20 to 240 mAs. Images were reconstructed using a reference reconstruction algorithm and four levels of an in‐house iterative reconstruction algorithm with different regularization strengths (IR1–IR4). The task‐based MTF and NPS were estimated from the measured images to create lookup tables of scaling factors that convert between d\u27gen and noise standard deviation. The performance of the proposed d\u27gen‐AEC method in providing a desired IQ level over a range of iterative reconstruction algorithms was evaluated using the American College of Radiology (ACR) phantom with elliptical shell and using a human reader evaluation on anthropomorphic phantom images. Results The study of the ACR phantom with elliptical shell demonstrated reasonable agreement between the d\u27gen predicted by the lookup table and d\u27 measured in the images, with a mean absolute error of 15% across all dose levels and maximum error of 45% at the lowest dose level with the elliptical shell. For the anthropomorphic phantom study, the mean reader scores for images resulting from the d\u27gen‐AEC method were 3.3 (reference image), 3.5 (IR1), 3.6 (IR2), 3.5 (IR3), and 2.2 (IR4). When using the d\u27gen‐AEC method, the observers’ IQ scores for the reference reconstruction were statistical equivalent to the scores for IR1, IR2, and IR3 iterative reconstructions (P \u3e 0.35). The d\u27gen‐AEC method achieved this equivalent IQ at lower dose for the IR scans compared to the reference scans. Conclusions A novel AEC method, based on a generalized detectability index, was investigated. The proposed method can be used with some existing AEC systems to derive the tube current profile for iterative reconstruction algorithms. The results provide preliminary evidence that the proposed d\u27gen‐AEC can produce similar IQ across different iterative reconstruction approaches at different dose levels

Multiethnic Meta-Analysis Identifies Ancestry-Specific and Cross-Ancestry Loci for Pulmonary Function

Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of European ancestry populations. We extend previous research by meta-analyzing genome-wide association studies of 1000 Genomes imputed variants in relation to pulmonary function in a multiethnic population of 90,715 individuals of European (N = 60,552), African (N = 8429), Asian (N = 9959), and Hispanic/Latino (N = 11,775) ethnicities. We identify over 50 additional loci at genome-wide significance in ancestry-specific or multiethnic meta-analyses. Using recent fine-mapping methods incorporating functional annotation, gene expression, and differences in linkage disequilibrium between ethnicities, we further shed light on potential causal variants and genes at known and newly identified loci. Several of the novel genes encode proteins with predicted or established drug targets, including KCNK2 and CDK12. Our study highlights the utility of multiethnic and integrative genomics approaches to extend existing knowledge of the genetics of lung function and clinical relevance of implicated loci

The White River Group of northwestern Nebraska: Stratigraphic revisions, correlations, and paleopedology

Revised lithologic correlations between type areas of the White River Group in Nebraska and South Dakota have resulted in a new lithostratigraphy for the lower part of the White River Group. The following pedostratigraphic and lithostratigraphic units, from oldest to youngest, are newly recognized in northwestern Nebraska and can be correlated with units in the Big Badlands of South Dakota: the Yellow Mounds Paleosol Equivalent, Interior and Weta Paleosol Equivalents, Chamberlain Pass Formation, and Peanut Peak Member of the Chadron Formation. The term Interior Paleosol Complex for the brightly colored zone at the base of the White River Group in northwestern Nebraska is abandoned in favor of a two-part division. The lower part is related to the Yellow Mounds Paleosol Series of South Dakota, which represents the pedogenically modified Cretaceous Pierre Shale. The upper part of this Complex is composed of the unconformably overlying, pedogenically modified overbank mudstone facies of the Chamberlain Pass Formation (which contains the Interior and Weta Paleosol Series in South Dakota). Greenish-white channel sandstones at the base of the White River Group in Nebraska (previously correlated with the Ahearn Member of the Chadron Formation in South Dakota) are here correlated with the channel sandstone facies of the Chamberlain Pass Formation in South Dakota. The Chamberlain Pass Formation is unconformably overlain by the Chadron Formation in South Dakota and Nebraska. Unlike the threefold division of the Chadron Formation into the Ahearn, Crazy Johnson, and Peanut Peak Members in South Dakota, only the bluish green, hummocky-weathering mudstones of the Peanut Peak Member are present in northwestern Nebraska. The remainder of the Chadron Formation in northwestern Nebraska, the Chadron B and Chadron C , is included within the newly defined Big Cottonwood Creek Member. The contact between the Peanut Peak and Big Cottonwood Creek Members of the Chadron Formation in northwestern Nebraska is intertonguing, except where strata of the Big Cottonwood Creek Member fill depressions and minor valleys in the Peanut Peak Member

SGDBR Single-Chip Wavelength Tunable Lasers for Swept Source OCT

Sampled Grating Distributed Bragg Reflector (SGDBR) monolithic tunable lasers are now entering the production phase in telecommunications applications. These tunable lasers are unique in that they offer wide wavelength tuning (1525 to 1565 nm), fast wavelength tuning (5 ns) and high speed amplitude modulation all on the same monolithic chip1,2,3,4. This work studies the applicability of SGDBR monolithic tunable laser diodes for biomedical imaging using swept-wavelength or Fourier domain optical coherence tomography. This paper will present our work involved with utilizing the strengths (table 1) of this SGDBR laser class and mitigating the weaknesses (table 2) of this device for swept-wavelength imaging applications. The strengths of the laser are its small size (portable solutions), wide wavelength range (good distance resolution), fast switching speeds (improved update rates), wide choice of center wavelengths, and lower power consumption. The weaknesses being addressed are the complicated wavelength tuning mechanism (3 wavelength control currents), wider laser linewidth (10s of MHz), moderate output power (10mW ), and the need for improved laser packaging. This paper will highlight the source characterization results and discuss an initial measurement architecture utilizing the SGDBR measurement engine