Surgical Management of an Indian Spotted Eagle with Compound Fracture of Humerus

An adult Indian Spotted Eagle (Aquila hastata) was presented with a history of being unable to fly. Clinical examination and radiography revealed a compound oblique fracture in the distal humerus of the right wing. The fracture site was grossly contaminated and the fragments were necrosed. Hence, to save the life of the bird, the wing was amputated under general anaesthesia, induced and maintained with ketamine. The surgical intervention led to uncomplicated recovery of an eagle

Retrieval of Pharyngeal Foreign Body Through Oral Approach in Three Dogs

Three dogs aged between 2 to 4 years old were presented to the Referral Veterinary Polyclinic, Indian Veterinary Research Institute, Izatnagar with clinical signs of anorexia, hypersalivation and repeated attempts at swallowing. Two cases showed shaking of head, pawing at the mouth and rubbing the head against wall, while in one case behavioral signs of depression were observed. Clinical examination and lateral plain radiograph of head and neck revealed radio opaque foreign body in the pharynx of all the animals. The foreign bodies were retrieved through the oral approach under general anaesthesia. This clinical paper reports the successful management of pharyngeal foreign bodies through oral approach using long curved artery forceps without any complication

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.

GWAS have identified >200 risk loci for Inflammatory Bowel Disease (IBD). The majority of disease associations are known to be driven by regulatory variants. To identify the putative causative genes that are perturbed by these variants, we generate a large transcriptome data set (nine disease-relevant cell types) and identify 23,650 cis-eQTL. We show that these are determined by ∼9720 regulatory modules, of which ∼3000 operate in multiple tissues and ∼970 on multiple genes. We identify regulatory modules that drive the disease association for 63 of the 200 risk loci, and show that these are enriched in multigenic modules. Based on these analyses, we resequence 45 of the corresponding 100 candidate genes in 6600 Crohn disease (CD) cases and 5500 controls, and show with burden tests that they include likely causative genes. Our analyses indicate that ≥10-fold larger sample sizes will be required to demonstrate the causality of individual genes using this approach

Combination of searches for Higgs boson decays into a photon and a massless dark photon using pp collisions at √s = 13 TeV with the ATLAS detector

A combination of searches for Higgs boson decays into a visible photon and a massless dark photon (H → γγd) is presented using 139 fb−1 of proton-proton collision data at a centre-of-mass energy of √s = 13 TeV recorded by the ATLAS detector at the Large Hadron Collider. The observed (expected) 95% confidence level upper limit on the Standard Model Higgs boson decay branching ratio is determined to be B(H → γγd) < 1.3% (1.5)%. The search is also sensitive to higher-mass Higgs bosons decaying into the same final state. The observed (expected) 95% confidence level limit on the cross-section times branching ratio ranges from 16 fb (20 fb) for mH = 400 GeV to 1.0 fb (1.5 fb) for mH = 3 TeV. Results are also interpreted in the context of a minimal simplified model

Surgical Management of an Indian Spotted Eagle with Compound Fracture of Humerus

An adult Indian Spotted Eagle (Aquila hastata) was presented with a history of being unable to fly. Clinical examination and radiography revealed a compound oblique fracture in the distal humerus of the right wing. The fracture site was grossly contaminated and the fragments were necrosed. Hence, to save the life of the bird, the wing was amputated under general anaesthesia, induced and maintained with ketamine. The surgical intervention led to uncomplicated recovery of an eagle

Retrieval of Pharyngeal Foreign Body Through Oral Approach in Three Dogs

Three dogs aged between 2 to 4 years old were presented to the Referral Veterinary Polyclinic, Indian Veterinary Research Institute, Izatnagar with clinical signs of anorexia, hypersalivation and repeated attempts at swallowing. Two cases showed shaking of head, pawing at the mouth and rubbing the head against wall, while in one case behavioral signs of depression were observed. Clinical examination and lateral plain radiograph of head and neck revealed radio opaque foreign body in the pharynx of all the animals. The foreign bodies were retrieved through the oral approach under general anaesthesia. This clinical paper reports the successful management of pharyngeal foreign bodies through oral approach using long curved artery forceps without any complication