296 research outputs found

    Activity patterns and behavior of Myocastor coypus in a gated community in the metropolitan area of Buenos Aires (Argentina)

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    Anthropization processes confront local wildlife with a new set of conditions that may lead to local extinctions or allow the expansion of some species. This is what happens with the coypu (Myocastor coypus) in gated communities in the metropolitan area of Buenos Aires (Argentina), where its rapid population growth results in continuous conflicts with the local inhabitants. The aim of this study was to document the daily and seasonal activity patterns and behavior of the coypu in an urban landscape within their natural distribution range. To achieve this, we conducted a camera-trap survey within areas occupied by the species from February to November 2018. The coypu activity was mainly crepuscular and nocturnal with variations between seasons. We found that the seasons with the greatest activity patterns overlap were winter and autumn (84%), while the least overlap was observed between summer and winter (53%). During the active periods, time spent on foraging behavior was dominant. Time dedicated to vigilance was greater in summer than in winter. This result, alongside an increase in nocturnal activity during summer, shows that coypu in this urban landscape shift its behavior when exposed to an increasing human activity. This study brings up more ecological data of this species, which is key to find alternative control methods within gated communities to lead to a harmonic relationship between inhabitants and the species in its native distribution.Fil: Salas, Magdalena. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Hernandez Hernandez, Julio C. Universidad Autónoma Metropolitana; MéxicoFil: Iglesias, Martín. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; ArgentinaFil: Corriale, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentin

    The Iberian Chain: tertiary inversion of a mesozoic intraplate basin

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    The Mesozoic Iberian basin developed inside the Iberian plate in the eastern end of the Tethys sea. As a result of the Tertiary convergence between the Iberian plate with the European and African plates, the Iberian basin was contractionally inverted, giving rise to the Iberian and Catalan Coastal chains and the surrounding Tertiary basins. The Bouguer anomaly map of the area shows that the Iberian Chain has crustal roots which would have produced during the Tertiary contractional period

    Clayey materials from the Sierra de la Demanda Range (Spain): their potential as raw materials for the building ceramics industry

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    This work describes the possible use of thick Early Cretaceous clay deposits, which occur in the southern sector of the Sierra de la Demanda range, as raw materials in the manufacture of ceramic articles. The global mineralogical composition is characterized by high proportions of phyllosilicates and quartz with variable quantities of feldspars, carbonates and hematite. The clay mineralogy differentiates two types of raw materials: illitic clay and kaolinitic-illitic clay. A granulometric distribution in the 2ÿ60 mm fraction, good behaviour during the drying stage and acceptable results in firing tests confirmed that most samples can be utilized as raw material in the building ceramics industry. The range of suitable firing temperatures for these materials is 950ÿ1000ëC, a temperature which needs to be raised for samples with a high percentage of kaolinite and quartz. Moreover, other materials with abundant calcite (20ÿ30%) are suitable for use as modifiers of some properties or colour

    Elastic properties of B-C-N films grown by N2-reactive sputtering from boron carbide targets

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    The following article appeared in Journal of Applied Physics 114.21 (2013): 213508 and may be found at http://scitation.aip.org/content/aip/journal/jap/114/21/10.1063/1.4837655Boron-carbon-nitrogen films were grown by RF reactive sputtering from a B4C target and N2 as reactive gas. The films present phase segregation and are mechanically softer than boron carbide films (a factor of more than 2 in Young's modulus). This fact can turn out as an advantage in order to select buffer layers to better anchor boron carbide films on substrates eliminating thermally induced mechanical tensions.This work has been supported by Spanish MINECO under contracts MAT2009-08786 and MAT2012-37276- C03-01 as well as by the Madrid Regional Government though contract S2009/MAT-1756

    Review of the effects of protection in marine protected areas: current knowledge and gaps

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    The effectiveness of marine protected areas (MPAs) and the conservation of marine environments must be based on reliable information on the quality of the marine environment that can be obtained in a reasonable timeframe. We reviewed studies that evaluated all aspects related to the effectiveness of MPAs in order to describe how the studies were conducted and to detect fields in which research is lacking. Existing parameters used to evaluate the effectiveness of MPAs are summarised. Two-hundred and twenty-two publications were reviewed. We identified the most commonly used study subjects and methodological approaches. Most of the studies concentrated on biological parameters. Peer reviewed studies were based on control vs. impact design. BACI and mBACI designs were used in very few studies. Through this review, we have identified gaps in the objectives assigned to MPAs and the way in which they have been evaluated. We suggest some guidelines aimedat improving the assessment of the effects of protection in MPAs

    Discontinuous transitions in double exchange materials

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    It is shown that the double exchange Hamiltonian, with weak antiferromagnetic interactions, has a rich variety of first order transitions between phases with different electronic densities and/or magnetizations. For band fillings in the range 0.3x0.50.3 \le x \le 0.5, and at finite temperatures, a discontinuous transition between phases with similar electronic densities but different magnetizations takes place. This sharp transition, which is not suppressed by electrostatic effects, and survives in the presence of an applied field, is consistent with the phenomenology of the doped manganites near the transition temperature.Comment: three more variational ansatzs considere

    High Mitochondrial DNA Stability in B-Cell Chronic Lymphocytic Leukemia

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    BACKGROUND: Chronic Lymphocytic Leukemia (CLL) leads to progressive accumulation of lymphocytes in the blood, bone marrow, and lymphatic tissues. Previous findings have suggested that the mtDNA could play an important role in CLL. METHODOLOGY/PRINCIPAL FINDINGS: The mitochondrial DNA (mtDNA) control-region was analyzed in lymphocyte cell DNA extracts and compared with their granulocyte counterpart extract of 146 patients suffering from B-Cell CLL; B-CLL (all recruited from the Basque country). Major efforts were undertaken to rule out methodological artefacts that would render a high false positive rate for mtDNA instabilities and thus lead to erroneous interpretation of sequence instabilities. Only twenty instabilities were finally confirmed, most of them affecting the homopolymeric stretch located in the second hypervariable segment (HVS-II) around position 310, which is well known to constitute an extreme mutational hotspot of length polymorphism, as these mutations are frequently observed in the general human population. A critical revision of the findings in previous studies indicates a lack of proper methodological standards, which eventually led to an overinterpretation of the role of the mtDNA in CLL tumorigenesis. CONCLUSIONS/SIGNIFICANCE: Our results suggest that mtDNA instability is not the primary causal factor in B-CLL. A secondary role of mtDNA mutations cannot be fully ruled out under the hypothesis that the progressive accumulation of mtDNA instabilities could finally contribute to the tumoral process. Recommendations are given that would help to minimize erroneous interpretation of sequencing results in mtDNA studies in tumorigenesis

    New approaches for the identification of KChIP2 ligands to study the KV4.3 channelosome in atrial fibrillati

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    Resumen del trabajo presentado en el VIII Congreso Red Española de Canales iónico, celebrado en Alicante (España) del 24 al 27 de mayo de 2022.Ion channels are macromolecular complexes present in the plasma membrane and in intracellular organelles of the cells, where they play important functions. The dysfunction of these channels results in several disorders named channelopathies, which represent a challenge for study and treatment.[1] We are focused on voltage-gated potassium channels, specifically on KV4.3. Kv4.3 is expressed in smooth muscle, heart and brain. Within the heart, Kv4.3 channels generate the transient outward potassium current (ITO). However, ITO characteristics are only observed when Kv4.3 assemble with accessory subunits as KChIP2 and DPP6. KV4.3 channelosome play a key role in atrial fibrillation (AF),the most common cardiac arrhythmia, with an estimated prevalence in the general population of 1.5–2%. However, current antiarrhythmic drugs for AF prevention have limited efficacy and considerable potential for adverse effects.[2] KChIP2 (Potassium Channel Interacting Protein 2) belongs to the calcium binding protein superfamily. It is the KChIP member predominantly expressed in heart and a key regulator of cardiac action potential duration. The identification of novel KChIP2 ligands could be useful to understand the role of KV4.3 channelosome in AF and it could help to discover new treatments for AF. [3] In this regard, structure-based virtual screening could be an important tool to accelerate the identification of novel KChIP2 ligands. In this communication, we will describe a multidisciplinary approach that, starting with a structurebased virtual screening, followed by an iterative process of synthesis/biological evaluation/docking studies, has led to the identification of new KChIP2 ligands.PID2019-104366RB-C21, PID2019-104366RB-C22, PID2020-114256RB-I00 and PID2020-119805RB-I00 grants funded by MCIN/AEI/10.13039/501100011033; and PIE202180E073 and 2019AEP148 funded by CSIC. C.V.B. holds PRE2020-093542 FPI grant funded by MCIN/AEI/10.13039/501100011033. PGS was recipient of an FPU grant (FPU17/02731). AB-B holds BES-2017-080184 FPI grant and A.P-L.holds RYC2018-023837-I grant both funded by MCIN/ AEI/ 10.13039/501100011033 and by “ESF Investing in your future
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