270 research outputs found

    Cutaneous apocrine cystomatosis in three slaughter-aged pigs

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    Apocrine cystomatosis is a rare condition characterized by clusters of cystically dilated sweat glands or other specialized apocrine glands. Cystic dilation of cutaneous sweat glands has been described in humans, dogs, and cats, but not in pigs, to our knowledge. We describe herein linear, brown, colloid-filled cavities < 1 cm diameter within the subcutaneous fat of the entire dorsal region of carcasses of three 6-mo-old pigs. These incidental findings were detected during meat inspection in 3 different slaughterhouses in Catalonia, Spain. Histopathology revealed multiple cystic cavities lined by flattened glandular epithelium, filled with proteinaceous material, and corresponding to cystic hyperplasia of sweat glands.info:eu-repo/semantics/acceptedVersio

    El Workshop on Engineering Applications 2016: Avanzando hacia el Reconocimiento Internacional

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    Workshop on Engineering Applications 2016: A Step Closer Towards International RecognitionLanguage: English El Workshop on Engineering Applications 2016: Avanzando hacia el reconocimiento internacionalIdioma: Inglé

    Stabilization of numerical formulations for convective-diffussive transport problems

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    European Congress on Computational Methods in Applied Sciences and Engineering, Barcelona 11-14 september 2000[Abstract] Numerical simulation in Fluid Mechanics is an extremely difficult task, wich complexity increases exponentially as the velocity of the fluid becomes higher. In particular, it is know that serious troubles are encountered when the FEM is applied to the resolution of high-advective fluid problems, despite the fact that the method has been successfully applied to a large number of sundry problems of Computational Mechanics. As a general rule, these drawbacks are announced by large oscillations of the Galerkin numerical solution in specific areas, or even through the whole domain. In order to understand the reasons for this unexpected behaviour, we focus our attention in the convective-diffusive transport differential equation, which can be interpreted as the linear version of the Navier-Stokes equations. By means of this simplified analysis, we try to identify the origin of the numerical oscillations phenomena, as much as to find a generic way to stabilize the numerical solution of the problem. In this paper we review the most significant alternative approaches that have been proposed to overcome these troubles when the Galerkin formulation is intended to solve the problem. Then, we propose a new technique that allows to obtain the stabilization parameters for the Petrov-Galerkin approach. Our procedure is baased on the eigenvalue analysis of the elemental matrices of the discretized problem. Thus, the outlined process could be applied independently on the specific formulation being used and the dimension of the problem being solved. Finally, we present different convective-diffusive numerical tests for different Péclet number.Xunta de Galicia; PGDIT99MAR1180

    Computing stabilization parameters in numerical models for advective-diffusive transport problems

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    [Abstract] Numerical modelling in Fluid Mechanics is particulary difficult in high-advective fluid problems. The Finite Element Method, which has been sucessfully applied to very challenging problems in Computational Mechanics, present some troubles in the resolution of high velocity fluid problems due to the appaerance of important oscillations of the sollution in specific parts of domain. In this paper, we consider the advective-diffuser trasport differential equation, which models a great number of problems in engineering. We briefly review the origin of the numerical oscillations and the alternative approaches proposed to overcome these phenomena, and we propose a procedure to obtain stabilization parameters in Petrov-Galerkin formulations from the eigenvalue analysis of the elemental matrices in the discretized problem. Finally, we present and discuss the result obtained for different tests problems.Xunta de Galicia; PGDIT99MAR1180

    Chronological brain lesions after SARS-CoV-2 infection in hACE2-transgenic mice

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    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes respiratory disease, but it can also affect other organs including the central nervous system. Several animal models have been developed to address different key questions related to Coronavirus Disease 2019 (COVID-19). Wild-type mice are minimally susceptible to certain SARS-CoV-2 lineages (beta and gamma variants), whereas hACE2-transgenic mice succumb to SARS-CoV-2 and develop a fatal neurological disease. In this article, we aimed to chronologically characterize SARS-CoV-2 neuroinvasion and neuropathology. Necropsies were performed at different time points, and the brain and olfactory mucosa were processed for histopathological analysis. SARS-CoV-2 virological assays including immunohistochemistry were performed along with a panel of antibodies to assess neuroinflammation. At 6 to 7 days post inoculation (dpi), brain lesions were characterized by nonsuppurative meningoencephalitis and diffuse astrogliosis and microgliosis. Vasculitis and thrombosis were also present and associated with occasional microhemorrhages and spongiosis. Moreover, there was vacuolar degeneration of virus-infected neurons. At 2 dpi, SARS-CoV-2 immunolabeling was only found in the olfactory mucosa, but at 4 dpi intraneuronal virus immunolabeling had already reached most of the brain areas. Maximal distribution of the virus was observed throughout the brain at 6 to 7 dpi except for the cerebellum, which was mostly spared. Our results suggest an early entry of the virus through the olfactory mucosa and a rapid interneuronal spread of the virus leading to acute encephalitis and neuronal damage in this mouse model.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The CBIG Consortium (constituted by IRTA-CReSA, BSC, and IrsiCaixa) is supported by Grifols pharmaceutical. The authors also acknowledge the crowdfunding initiative of https://www.yomecorono.com.Peer Reviewed"Article signat per 12 autors/es: Enric Vidal*, Carlos López-Figueroa*, Jordi Rodon, Mónica Pérez, Marco Brustolin, Guillermo Cantero, Víctor Guallar, Nuria Izquierdo-Useros, Jorge Carrillo, Julià Blanco, Bonaventura Clotet, Júlia Vergara-Alert, Joaquim Segalés"Postprint (published version

    FACTORES DE RIESGO DE LA HIPERTENSIÓN ARTERIAL Y LA SALUD CARDIOVASCULAR EN ESTUDIANTES UNIVERSITARIOS

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    The goal was to determine the hypertension risk factors and cardiovascular health in college students. 110 students were divided in: a) cases group (n=52) with hypertension family antecedent, and b) control group (n=58) without hypertension family antecedent. Both groups were evaluated with the Hypertension Family Antecedent Inventory and the Hypertension Risk Factors Inventory. The risk factors that were reported in both groups were: diabetes family antecedent, high intake of fat food, stressful environment perception, and stressful personality. It is discussed that he hypertension risk factors reported in the college students indicates that this is a vulnerable group to suffer from cardiovascular disease. Also, the absence of risk factors (v.gr. smoking, alcohol) in this group is an opportunity for the psychologist to prevent diseases and control the risk factors through, for example, the cardiovascular health promotion.El objetivo fue determinar los factores de riesgo de la hiperten-sión arterial en estudiantes universitarios. Participaron 110 estudiantes normotensos divididos en: a) grupo de casos (N= 52), con antecedente familiar de hipertensión, y b) grupo de controles (N= 58), sin antecedente familiar de hipertensión. En los dos grupos se aplicaron el Cuestionario para detectar antecedentes familiares de hipertensión arterial y el Inventa-rio de Factores de Riesgo de Hipertensión (IFRH) (Grijalva, 1992). Los factores de riesgo que predominaron en ambos grupos fueron anteceden-tes familiares de diabetes, alto consumo de alimentos con grasas, percep-ción del medio ambiente como estresante y personalidad estresante. Se discute sobre la presencia de factores de riesgo de la hipertensión arterial en los sujetos universitarios sanos la cual indica que se trata de una pobla-ción proclive a padecer problemas cardiovasculares. Asimismo, la ausencia de factores de riesgo (por ejemplo, tabaquismo, alcoholismo) en la pobla-ción universitaria también debe observarse como una oportunidad del psicólogo para prevenir enfermedades y controlar los factores de riesgo a través de, por ejemplo, promoción de la salud cardiovascular

    Extended spawning in brown trout (Salmo trutta) populations from the Southern Iberian Peninsula: the role of climate variability

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    The reproductive periods of brown trout (Salmo trutta) populations in 12 rivers in the Baetic Mountains in southern Spain were studied from 2008 to 2013. This area is an ecological and geographical limit for the distribution of this species in Europe. We found that the spawning period has been markedly extended in these fish. The mean spawning dates in the studied populations are consistent with the European trend at this latitude, but our data suggest that females from most of the populations that we studied are able to produce eggs from early October through late April or early May, yielding a reproductive period of between 150 and 170 days, the longest and most delayed brown trout reproduction periods that have been reported in the literature. We believe that such expanded spawning periods result primarily from the unpredictability of the Mediterranean climate, although it is possible that other factors may have contributed to the development of this reproductive behaviour. This hypothesis is discussed in the context of a comparison of our results with those found for other European S. trutta populations.This study is framed in the projects Recuperación de las poblaciones de trucha común en Andalucía (1589/2007/M/00) and Seguimiento de los efectos del Cambio Global en Sierra Nevada: 2010-2014 (562/2010/M/00)

    Algoritmo iterativo para la planeación de la producción mixta basado en la función acumulativa de pertenencia

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    This paper shows an application of a novel algorithm for Fuzzy Linear Programming (FLP) problems with both fuzzy technological coefficients and constraints, which deals with any kind of fuzzy membership functions for technological parameters and fuzzy linear constraints.The presented approach uses an iterative algorithm which finds stable solutions to problems with fuzzy parameter sinboth sides of an FLP problem. The algorithm is based on the soft constraints method proposed by Zimmermann combined with an iterative procedure which gets a single optimal solution.Este artículo presenta una aplicación de un algoritmo nuevo para problemas de programación lineal difusa (FLP) con restricciones y coeficientes difusos, con restricciones difusas lineales y coeficientes tecnológicos difusos con funciones de pertenencia no-lineales.El modelo propuesto usa un método iterativo que encuentra una solución estable aproblems con parámetros difusos en ambos lados de las restricciones de un problema de programación lineal. El algoritmo se basa en el método de restricciones suaves propuesto por Zimmermann, combinado con una rutina iterativa que llega a soluciones óptmas únicas

    Propuesta didáctica para la enseñanza de las voces náhuatl a través de la escritura de anécdotas en secundaria

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    En este estudio se plantea la enseñanza de las voces náhuatl, a través de la escritura de la anécdota en estudiantes de undécimo grado de secundaria, desde un enfoque por competencias, con el objetivo de fundamentar una secuencia didáctica que promueva el aprendizaje de esta temática. Para la realización de este trabajo investigativo se aplicó una prueba diagnóstica en el Colegio Público Guardabarranco a estudiantes de undécimo grado con la finalidad de analizar el nivel de conciencia lingüística que tienen los estudiantes en el reconocimiento del sustrato náhuatl. Entre los resultados obtenidos se puede mencionar que los estudiantes en su mayoría usan palabras del náhuatl, sin embargo, no logran reconocer su procedencia, lo cual manifiesta una falta de conciencia lingüística. De igual forma, se logró apreciar que los nahualismos no son usados en algunos contextos de habla a consecuencia del prejuicio lingüístico existente en ellos, ya que manifestaron que estas palabras las consideran informales. Por otro lado, un sector minoritario señaló usarlas en contextos formales debido a que son palabras características del habla nicaragüense. Por último, se detectó un nivel poco considerable de conocimientos acerca de los sinónimos de estos vocablos. A partir de los problemas identificados se diseñó una secuencia didáctica distribuida en tres fases que contiene sesiones con actividades creativas e integrales dirigidas a la enseñanza de las voces náhuatl a través de la escritura de anécdota para brindar soluciones a la problemática que se encontró
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