Multilevel Monte Carlo and control-variate simulation of Coulomb collisions

Abstract. The multilevel Monte Carlo and the control-variate method are reviewed for simulation of Coulomb collisions. The test case considered is fast-ion relaxation from ion-ion and electron-ion collisions against a Maxwellian background. A simplified energy scattering model is derived and related to the Cox-Ingersoll-Ross model for which, an exact time dependent solution can be obtained. The exact model is used as a control-variate for the estimation of the mean energy

Toroidal effects on ICRF heating and current drive

Numerical studies, performed with the Monte-Carlo code FIDO [1], of the evolution of the resonant-ion distribution function in the presence of ICRH in toroidal geometry are presented. In particular it is pointed out how the absorption of toroidal momentum from a wave field with finite parallel wave numbers causes spatial drift and diffusion, which together with the finite orbit widths of the tail ions is shown to have a large effect on the temperature profile of the resonant ion species and also to cause losses of high-energy ions to the wall [2]. Furthermore, it is found that the finite orbit width and the inward drift occuring for negative parallel wave numbers [3] each give rise to a new mechanism of minority-ion cyclotron current drive as compared to earlier models where the drift orbits of the resonant ions are confined to the magnetic flux surfaces. For high levels of coupled power these new mechanisms are found to be the dominating ones [4,5]

Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects

Maximal physical exertion is accompanied by increased degradation of purine nucleotides in muscles with the products of purine catabolism accumulating in the plasma. Thanks to membrane transporters, these products remain in an equilibrium between the plasma and red blood cells where they may serve as substrates in salvage reactions, contributing to an increase in the concentrations of purine nucleotides. In this study, we measured the concentrations of adenine nucleotides (ATP, ADP, AMP), inosine nucleotides (IMP), guanine nucleotides (GTP, GDP, GMP), and also pyridine nucleotides (NAD, NADP) in red blood cells immediately after standardized physical effort with increasing intensity, and at the 30th min of rest. We also examined the effect of muscular exercise on adenylate (guanylate) energy charge—AEC (GEC), and on the concentration of nucleosides (guanosine, inosine, adenosine) and hypoxanthine. We have shown in this study that a standardized physical exercise with increasing intensity leads to an increase in IMP concentration in red blood cells immediately after the exercise, which with a significant increase in Hyp concentration in the blood suggests that Hyp was included in the IMP pool. Restitution is accompanied by an increase in the ATP/ADP and ADP/AMP ratios, which indicates an increase in the phosphorylation of AMP and ADP to ATP. Physical effort applied in this study did not lead to changes in the concentrations of guanine and pyridine nucleotides in red blood cells

Studying the WHIM Content of the Galaxy Large-Scale Structures along the Line of Sight to H 2356-309

We make use of a 500ks Chandra HRC-S/LETG spectrum of the blazar H2356-309, combined with a lower S/N spectrum of the same target, to search for the presence of warm-hot absorbing gas associated with two Large-Scale Structures (LSSs) crossed by this sightline at z=0.062 (the Pisces-Cetus Supercluster, PCS) and at z=0.128 ("Farther Sculptor Wall", FSW). No statistically significant (>=3sigma) individual absorption is detected from any of the strong He- or H-like transitions of C, O and Ne at the redshifts of the structures. However we are still able to constrain the physical and geometrical parameters of the associated putative absorbing gas, by performing joint spectral fit of marginal detections and upper limits of the strongest expected lines with our self-consistent hybrid ionization WHIM spectral model. At the redshift of the PCS we identify a warm phase with logT=5.35_-0.13^+0.07 K and log N_H =19.1+/-0.2 cm^-2 possibly coexisting with a hotter and less significant phase with logT=6.9^+0.1_-0.8 K and log N_H=20.1^+0.3_-1.7 cm^-2 (1sigma errors). For the FSW we estimate logT=6.6_-0.2^+0.1 K and log N_H=19.8_-0.8^+0.4 cm^-2. Our constraints allow us to estimate the cumulative number density per unit redshifts of OVII WHIM absorbers. We also estimate the cosmological mass density obtaining Omega_b(WHIM)=(0.021^+0.031_-0.018) (Z/Z_sun)^-1, consistent with the mass density of the intergalactic 'missing baryons' for high metallicities.Comment: 29 pages, 8 figures, 4 tables. Accepted for publication in Ap

Perpendicular momentum injection by lower hybrid wave in a tokamak

The injection of lower hybrid waves for current drive into a tokamak affects the profile of intrinsic rotation. In this article, the momentum deposition by the lower hybrid wave on the electrons is studied. Due to the increase in the poloidal momentum of the wave as it propagates into the tokamak, the parallel momentum of the wave increases considerably. The change of the perpendicular momentum of the wave is such that the toroidal angular momentum of the wave is conserved. If the perpendicular momentum transfer via electron Landau damping is ignored, the transfer of the toroidal angular momentum to the plasma will be larger than the injected toroidal angular momentum. A proper quasilinear treatment proves that both perpendicular and parallel momentum are transferred to the electrons. The toroidal angular momentum of the electrons is then transferred to the ions via different mechanisms for the parallel and perpendicular momentum. The perpendicular momentum is transferred to ions through an outward radial electron pinch, while the parallel momentum is transferred through collisions.Comment: 22 pages, 4 figure

Ischemic Preconditioning Improves Microvascular Endothelial Function in Remote Vasculature by Enhanced Prostacyclin Production.

BACKGROUND The mechanisms underlying the effect of preconditioning on remote microvasculature remains undisclosed. The primary objective was to document the remote effect of ischemic preconditioning on microvascular function in humans. The secondary objective was to test if exercise also induces remote microvascular effects. METHODS AND RESULTS A total of 12 healthy young men and women participated in 2 experimental days in a random counterbalanced order. On one day the participants underwent 4×5 minutes of forearm ischemic preconditioning, and on the other day they completed 4×5 minutes of hand-grip exercise. On both days, catheters were placed in the brachial and femoral artery and vein for infusion of acetylcholine, sodium nitroprusside, and epoprostenol. Vascular conductance was calculated from blood flow measurements with ultrasound Doppler and arterial and venous blood pressures. Ischemic preconditioning enhanced (P<0.05) the remote vasodilator response to intra-arterial acetylcholine in the leg at 5 and 90 minutes after application. The enhanced response was associated with a 6-fold increase (P<0.05) in femoral venous plasma prostacyclin levels and with a transient increase (P<0.05) in arterial plasma levels of brain-derived neurotrophic factor and vascular endothelial growth factor. In contrast, hand-grip exercise did not influence remote microvascular function. CONCLUSIONS These findings demonstrate that ischemic preconditioning of the forearm improves remote microvascular endothelial function and suggest that one of the underlying mechanisms is a humoral-mediated potentiation of prostacyclin formation