A Chandra Proper Motion for PSR J1809-2332

We report on a new Chandra exposure of PSR J1809-2332, the recently discovered pulsar powering the bright EGRET source 3EG J1809-2328. By registration of field X-ray sources in an archival exposure, we measure a significant proper motion for the pulsar point source over an ~11 year baseline. The shift of 0.30+/-0.06" (at PA= 153.3+/-18.4) supports an association with proposed SNR parent G7.5-1.7. Spectral analysis of diffuse emission in the region also supports the interpretation as a hard wind nebula trail pointing back toward the SNR.Comment: To Appear in the Astrophysical Journal, Sept 1 (v. 756

SNAP judgments: A small N acceptability paradigm (SNAP) for linguistic acceptability judgments

While published linguistic judgments sometimes differ from the judgments found in large-scale formal experiments with naive participants, there is not a consensus as to how often these errors occur nor as to how often formal experiments should be used in syntax and semantics research. In this article, we first present the results of a large-scale replication of the Sprouse et al. 2013 study on 100 English contrasts randomly sampled from Linguistic Inquiry 2001–2010 and tested in both a forced-choice experiment and an acceptability rating experiment. Like Sprouse, Schütze, and Almeida, we find that the effect sizes of published linguistic acceptability judgments are not uniformly large or consistent but rather form a continuum from very large effects to small or nonexistent effects. We then use this data as a prior in a Bayesian framework to propose a small n acceptability paradigm for linguistic acceptability judgments (SNAP Judgments). This proposal makes it easier and cheaper to obtain meaningful quantitative data in syntax and semantics research. Specifically, for a contrast of linguistic interest for which a researcher is confident that sentence A is better than sentence B, we recommend that the researcher should obtain judgments from at least five unique participants, using at least five unique sentences of each type. If all participants in the sample agree that sentence A is better than sentence B, then the researcher can be confident that the result of a full forced-choice experiment would likely be 75% or more agreement in favor of sentence A (with a mean of 93%). We test this proposal by sampling from the existing data and find that it gives reliable performance.*American Society for Engineering Education. National Defense Science and Engineering Graduate Fellowshi

Remarks on Resonant Scalars in the AdS/CFT Correspondence

The special properties of scalars having a mass such that the two possible dimensions of the dual scalar respect the unitarity and the Breitenlohner-Freedman bounds and their ratio is integral (``resonant scalars'') are studied in the AdS/CFT correspondence. The role of logarithmic branches in the gravity theory is related to the existence of a trace anomaly and to a marginal deformation in the Conformal Field Theory. The existence of asymptotic charges for the conformal group in the gravity theory is interpreted in terms of the properties of the corresponding CFT.Comment: 16 pages, 1 figur

Case Study of a Comprehensive Team-Based Approach to Increase Colorectal Cancer Screening

Introduction: Colorectal cancer is the second leading cause of cancer deaths among men and women in West Virginia. In addition, 51% of all colorectal cancers diagnosed in West Virginia from 2012 to 2016 were detected at either regional (31%) or distant (20%) stages indicating a need for improved early detection. Methods: West Virginia University Cheat Lake Physicians participated in the West Virginia Program to Increase Colorectal Cancer Screening, a program of Cancer Prevention and Control at the WVU Cancer Institute. As a result, Cheat Lake Physicians assembled a team of health care professionals to implement evidence-based interventions and system changes including provider assessment and feedback, patient reminders, accurate data capture, and tracking of CRC screening tests. Results: These efforts resulted in a 15.8% increase in colorectal cancer screening rates within one year of implementation. Additionally, the clinic achieved a 66% return rate for Fecal Immunochemical Test kits, an inexpensive, stool-based colorectal cancer screening test. Implications: The utilization of a team-based approach to patient care yields positive results that can be carried over to other cancer and disease prevention efforts in primary care clinics

Research on rare diseases:ten years of progress and challenges at IRDiRC

The International Rare Diseases Research Consortium (IRDiRC) is a global collaborative initiative launched in 2011, aimed at tackling rare diseases through research. Here, we summarize IRDiRC’s vision and goals and highlight achievements and prospects after its first decade.</p

Microbial Community Field Surveys Reveal Abundant Pseudomonas Population in Sorghum Rhizosphere Composed of Many Closely Related Phylotypes

While the root-associated microbiome is typically less diverse than the surrounding soil due to both plant selection and microbial competition for plant derived resources, it typically retains considerable complexity, harboring many hundreds of distinct bacterial species. Here, we report a time-dependent deviation from this trend in the rhizospheres of field grown sorghum. In this study, 16S rRNA amplicon sequencing was used to determine the impact of nitrogen fertilization on the development of the root-associated microbiomes of 10 sorghum genotypes grown in eastern Nebraska. We observed that early rhizosphere samples exhibit a significant reduction in overall diversity due to a high abundance of the bacterial genus Pseudomonas that occurred independent of host genotype in both high and low nitrogen fields and was not observed in the surrounding soil or associated root endosphere samples. When clustered at 97% identity, nearly all the Pseudomonas reads in this dataset were assigned to a single operational taxonomic unit (OTU); however, exact sequence variant (ESV)-level resolution demonstrated that this population comprised a large number of distinct Pseudomonas lineages. Furthermore, single-molecule long-read sequencing enabled high-resolution taxonomic profiling revealing further heterogeneity in the Pseudomonas lineages that was further confirmed using shotgun metagenomic sequencing. Finally, field soil enriched with specific carbon compounds recapitulated the increase in Pseudomonas, suggesting a possible connection between the enrichment of these Pseudomonas species and a plant-driven exudate profile

Analysis of new high-precision transit light curves of WASP-10 b: starspot occultations, small planetary radius, and high metallicity

The WASP-10 planetary system is intriguing because different values of radius have been reported for its transiting exoplanet. The host star exhibits activity in terms of photometric variability, which is caused by the rotational modulation of the spots. Moreover, a periodic modulation has been discovered in transit timing of WASP-10 b, which could be a sign of an additional body perturbing the orbital motion of the transiting planet. We attempt to refine the physical parameters of the system, in particular the planetary radius, which is crucial for studying the internal structure of the transiting planet. We also determine new mid-transit times to confirm or refute observed anomalies in transit timing. We acquired high-precision light curves for four transits of WASP-10 b in 2010. Assuming various limb-darkening laws, we generated best-fit models and redetermined parameters of the system. The prayer-bead method and Monte Carlo simulations were used to derive error estimates. Three transit light curves exhibit signatures of the occultations of dark spots by the planet during its passage across the stellar disk. The influence of stellar activity on transit depth is taken into account while determining system parameters. The radius of WASP-10 b is found to be no greater than 1.03 Jupiter radii, a value significantly smaller than most previous studies indicate. We calculate interior structure models of the planet, assuming a two-layer structure with one homogeneous envelope atop a rock core. The high value of the WASP-10 b's mean density allows one to consider the planet's internal structure including 270 to 450 Earth masses of heavy elements. Our new mid-transit times confirm that transit timing cannot be explained by a constant period if all literature data points are considered. They are consistent with the ephemeris assuming a periodic variation of transit timing...Comment: Accepted for publication in A&

Microbial Community Field Surveys Reveal Abundant Pseudomonas Population in Sorghum Rhizosphere Composed of Many Closely Related Phylotypes

While the root-associated microbiome is typically less diverse than the surrounding soil due to both plant selection and microbial competition for plant derived resources, it typically retains considerable complexity, harboring many hundreds of distinct bacterial species. Here, we report a time-dependent deviation from this trend in the rhizospheres of field grown sorghum. In this study, 16S rRNA amplicon sequencing was used to determine the impact of nitrogen fertilization on the development of the root-associated microbiomes of 10 sorghum genotypes grown in eastern Nebraska. We observed that early rhizosphere samples exhibit a significant reduction in overall diversity due to a high abundance of the bacterial genus Pseudomonas that occurred independent of host genotype in both high and low nitrogen fields and was not observed in the surrounding soil or associated root endosphere samples. When clustered at 97% identity, nearly all the Pseudomonas reads in this dataset were assigned to a single operational taxonomic unit (OTU); however, exact sequence variant (ESV)-level resolution demonstrated that this population comprised a large number of distinct Pseudomonas lineages. Furthermore, single-molecule long-read sequencing enabled high-resolution taxonomic profiling revealing further heterogeneity in the Pseudomonas lineages that was further confirmed using shotgun metagenomic sequencing. Finally, field soil enriched with specific carbon compounds recapitulated the increase in Pseudomonas, suggesting a possible connection between the enrichment of these Pseudomonas species and a plant-driven exudate profile

The Demonstration of a Robotic External Leak Locator for the International Space Station

The International Space Station (ISS) and all currently conceivable future manned spacecraft are susceptible to mission impacts due to fluid/gas leaks to the exterior environment. For example, there is a well-known risk of ammonia leaks from the ISS External Active Thermal Control System (EATCS) loops and as of 2016 there was no method to locate them. It was, therefore, critical to develop a method for detecting and locating leaks to preserve vehicle health. The Robotic External Leak Locator (RELL) was developed and deployed to the ISS to provide this capability. An on-orbit validation and demonstration was successfully completed in December 2016 and leak locating operations occurred in February 2017. This paper discusses the results of these exercises including measurements of the environment around ISS, detection of a small ammonia leak and implementation of leak locating methodologies. RELL is a collaboration between NASA's Goddard Space Flight Center (GSFC) and Johnson Space Center (JSC) and was launched to the ISS as a Technology Demonstration Payload in December 2015 on Orbital-ATK Commercial Resupply Flight 4

MADNESS: A Multiresolution, Adaptive Numerical Environment for Scientific Simulation

MADNESS (multiresolution adaptive numerical environment for scientific simulation) is a high-level software environment for solving integral and differential equations in many dimensions that uses adaptive and fast harmonic analysis methods with guaranteed precision based on multiresolution analysis and separated representations. Underpinning the numerical capabilities is a powerful petascale parallel programming environment that aims to increase both programmer productivity and code scalability. This paper describes the features and capabilities of MADNESS and briefly discusses some current applications in chemistry and several areas of physics