Methods for estimating the density of Elaphostrongylus rangiferi Mitskevich (Nematoda, Metastrongyloidea) larvae in faeces from reindeer, Rangifer tarandus L.

A method for estimating the density of Elaphostrongylus rangiferi larvae in reindeer faeces that have been deep frozen is described. The method involves the use of an inverted microscope with plankton counting chambers. Statistical data on the efficiency and sensitivity of the method are given. With fresh faeces, the results obtained with the method were not significantly different from those obtained with the Baermann technique. With faeces that had been stored in deep freeze, the method detected on average 30 per cent more larvae than the Baermann technique.Metoder for å estimere tettheten av hjernemarklarver i avføring fra reinsdyr.Abstract in Norwegian / Sammendrag: En metode for å estimere tettheten av hjernemarklarver i avføring som har vært dypfryst blir beskrevet. Anvendelse av et invertert mikroskop med plankton tellekammer inngår i metoden. Det blir gitt statistiske data for metodens effektivitet og følsomhet. Ved undersøkelse av fersk avføring skilte ikke de resultatene metoden ga seg fra de som ble oppnådd med Baermanns metode. Ved undersøkelse av avføring som hadde vært lagret dypfrosset ga metoden i gjennomsnitt 30 prosent flere larver enn Baermanns metode

Service users’ experiences with mobile safety alarms in home care: A qualitative study

Aim To investigate service users of home-based care experiences of using mobile safety alarm and how the alarm affects their ability to cope with everyday life. Design A qualitative study with semi-structured interviews. Methods The data were collected through semi-structured interviews and analysed according to systematic text condensation. Four men and six women, between 47 and 85 years of age, were included in the study. Results Three main themes emerged in the analysis: dimensions of safety, the functionality of the alarm and variation in user guidance. The greatest benefit of having a mobile safety alarm was the feeling of safety. Moreover, the certainty of obtaining contact with the health professionals in any situation was highly valued. However, regarding implementation of the mobile safety alarm, the findings revealed a varying understanding among the service users. Nevertheless, the need for social interaction in their everyday lives is an important factor to recognize

Complex Line Bundles over Simplicial Complexes and their Applications

Discrete vector bundles are important in Physics and recently found remarkable applications in Computer Graphics. This article approaches discrete bundles from the viewpoint of Discrete Differential Geometry, including a complete classification of discrete vector bundles over finite simplicial complexes. In particular, we obtain a discrete analogue of a theorem of Andr\'e Weil on the classification of hermitian line bundles. Moreover, we associate to each discrete hermitian line bundle with curvature a unique piecewise-smooth hermitian line bundle of piecewise constant curvature. This is then used to define a discrete Dirichlet energy which generalizes the well-known cotangent Laplace operator to discrete hermitian line bundles over Euclidean simplicial manifolds of arbitrary dimension

Teachers’ participation in evaluating a web-based tool to monitor intervention fidelity

Background When educational interventions are carried out, it is important that they are undertaken in a way that is aligned with the intervention plan: in other words, that they demonstrate fidelity to the intervention. A significant research issue is how fidelity can be monitored in a time-efficient and cost-effective way in classrooms and whether technology could help to provide innovative solutions in this regard. Purpose Through collaboration with teachers, this exploratory study sought to ascertain the usability of a web-based fidelity application (WFA). The WFA was being developed as a checklist tool to help teachers monitor the implementation fidelity of a social and emotional learning intervention for 14- to 15-year-old students in Norway. Method For this qualitative study, data were collected at two time points: (i) through a focus group interview with six teachers who had piloted the WFA prior to the initiation of the intervention; and (ii) via individual interviews with five teachers in the intervention group who had used the WFA during the implementation process. The data were analysed thematically. Findings According to the analysis, the teachers considered that the WFA’s features (e.g. layout and registration process) could help support the ease and efficiency of fidelity reporting. They felt that it provided a highly recognisable link with the intervention material. In addition, the teachers provided ideas for further development and potential improvements. In all, the WFA was perceived as having high usability, suggesting its potential value as a useful tool for the collection of fidelity data. Conclusion This paper highlights the crucial role of teacher participation and the importance of fidelity data in the conduct of educational interventions. It draws attention to the need for user-friendly tools to support teachers to monitor fidelity in ways that do not involve high time and cost burdens. Similar WFAs could be of potential use in many different kinds of educational interventions in classroom settings internationally.publishedVersio

ANALYSIS OF ELITE GOLFERS’ KINEMATIC SEQUENCE IN FULL-SWING AND PARTIAL SWING SHOTS

INTRODUCTION: Proximal-to-distal sequencing (PDS) has been observed in full-swing golf shots as in most throwing and striking skills, where the main goal is to maximize speed in the most distal segment of an open-link system (Zheng et al., 2007). Although PDS primarily is associated with mechanical advantage when the speed requirement is high, this temporal order has also been found and ascribed various merits in relatively slow multi-joint movements (Furuya & Kinoshita, 2007). However, no research to date has examined the sequencing pattern in partial golf shots to submaximal distances. The purpose here was to investigate whether PDS is a common characteristic also in partial swing shots of skilled golf players. METHODS: A total of 47 golfers were investigated, 11 male tournament professionals, 23 male amateurs (HCP 0 ± 2 strokes), and 13 female amateurs (HCP -2 ± 2 strokes) performed partial shots with a wedge to targets at three discrete distances (40, 55 and 70 m), and full-swing shots with a five iron as well as a driver in the same direction for maximal distance. Pelvis, upper torso, and hand movement were recorded in 3D with an electromagnetic tracking system (Polhemus) at 240 Hz. The magnitude of the resultant angular velocity vector of each segment was used to examine the sequencing pattern and the angular speed of segment motions. Movement onset, peak amplitude and time for peak amplitude were analyzed in separate repeated-measure ANOVAs with pre-planned Bonferroni corrected pairwise comparisons. Significance level was set at P < 0.05. RESULTS: This study showed a significant proximal-to-distal temporal relationship of movement onset and maximum angular speed at the pelvis, upper torso and hand segments in the golf swing. The same temporal structure was evident in all test conditions, as well as among different genders and levels of expertise. However, the increment in angular speed from the upper torso to hand were significantly larger for male professionals than for female amateurs at all shot conditions and significantly larger for male amateurs than for female amateurs at full-swing shots. DISCUSSION AND CONCLUSION: While there exists a body of evidence in support for PDS providing mechanical advantages when the highest possible ball speed is to be achieved, merits of PDS in partial golf shots are less evident. However, it has been proposed that a given torque or force can be more accurately generated by a stronger muscle than a weaker muscle (Hamilton et al., 2004) and a potential role of the observed sequencing pattern in partial shots of skilled golf players could be to improve accuracy and minimize the speed-accuracy tradeoff. REFERENCES: Zheng N., Barrentine S.W., Fleizig G.S., Andrews J.R. (2008). Kinematic analysis of swing in pro and amateur golfers, International Journal of Sports Medicine, 6, 487-493. Furuya S., Kinoshita H. (2007). Roles of proximal-to-distal sequential organization of the upper limb segments in striking the keys by expert pianists, Neuroscience Letters, 421, 264-269. Hamilton A., Jones K.E., Wolpert D.M. (2004). The scaling of motor noise with muscle strength and motor unit number in humans, Experimental Brain Research, 157, 417-430

Culturally safe speech-language supports for First Nations children: Achieving Sustainable Development Goals 3, 4, 8 and 10

Purpose: Self-determination is foundational to health and well-being for First Nations people. Colonisation has undermined self-determination and widespread effects are observed as disparities in health and well-being. Chronic middle ear disease is more highly prevalent in First Nations children, is associated with delays in speech and language and lower levels of educational readiness. However, there is a paucity of culturally and linguistically sensitive speech-language assessments and habilitation services globally. Focussing on high-income colonial-settler countries (including United States, Canada, Australia and New Zealand), where health disparities are significant, we aim to discuss the importance of and the challenges in providing culturally safe care to First Nations children with communication disabilities. Result: To be effective, both cultural and linguistic diversity and cultural safety must be considered in all aspects of assessment and intervention. Furthermore, speech-language pathologists must be equipped to work with First Nations children with communication disorders. Conclusion: To optimally support First Nations’ children with communication disabilities, services need to be culturally safe, family-centred and strengths-based. This commentary focuses on the United Nations Sustainable Development Goals (SDGs)3, 4, 8 and 10

A Project Based Approach to Statistics and Data Science

In an increasingly data-driven world, facility with statistics is more important than ever for our students. At institutions without a statistician, it often falls to the mathematics faculty to teach statistics courses. This paper presents a model that a mathematician asked to teach statistics can follow. This model entails connecting with faculty from numerous departments on campus to develop a list of topics, building a repository of real-world datasets from these faculty, and creating projects where students interface with these datasets to write lab reports aimed at consumers of statistics in other disciplines. The end result is students who are well prepared for interdisciplinary research, who are accustomed to coping with the idiosyncrasies of real data, and who have sharpened their technical writing and speaking skills

The psychological burden of skin diseases: a cross-sectional multicenter study among dermatological out-patients in 13 European countries.

The contribution of psychological disorders to the burden of skin disease has been poorly explored, and this is a large-scale study to ascertain the association between depression, anxiety, and suicidal ideation with various dermatological diagnoses. This international multicenter observational cross-sectional study was conducted in 13 European countries. In each dermatology clinic, 250 consecutive adult out-patients were recruited to complete a questionnaire, reporting socio-demographic information, negative life events, and suicidal ideation; depression and anxiety were assessed with the Hospital Anxiety and Depression Scale. A clinical examination was performed. A control group was recruited among hospital employees. There were 4,994 participants--3,635 patients and 1,359 controls. Clinical depression was present in 10.1% patients (controls 4.3%, odds ratio (OR) 2.40 (1.67-3.47)). Clinical anxiety was present in 17.2% (controls 11.1%, OR 2.18 (1.68-2.82)). Suicidal ideation was reported by 12.7% of all patients (controls 8.3%, OR 1.94 (1.33-2.82)). For individual diagnoses, only patients with psoriasis had significant association with suicidal ideation. The association with depression and anxiety was highest for patients with psoriasis, atopic dermatitis, hand eczema, and leg ulcers. These results identify a major additional burden of skin disease and have important clinical implications.Peer reviewedFinal Published versio

Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate

Isoform 4 of the human peptidylarginine deiminase (hPAD4) enzyme may be responsible for the citrullination of antigens in rheumatoid arthritis (RA) and has been shown to be itself the target of disease-specific autoantibodies. Here, we have tested whether the level of serum anti-hPAD4 antibodies in RA patients is stable over a period of 10 years and whether the antibodies influence hPAD4-mediated deimination of the small substrate N-α-Benzoyl-l-arginine ethyl ester. RA sera (n = 128) obtained at baseline and after 10 years were assessed for anti-hPAD4 antibodies by a specific immunoassay. For 118 RA patients, serum anti-hPAD4 IgG levels were stable over 10 years. Seven patients who were negative for anti-PAD4 IgG at baseline had become positive after 10 years. Further, total IgG from selected RA patients and controls were purified, and a fraction was depleted for anti-hPAD4 antibodies. Kinetic deimination assays were performed with total IgG and depleted fractions. The kcat and Km values of hPAD4-mediated deimination of N-α-Benzoyl-l-arginine ethyl ester were not affected by the depletion of the anti-hPAD4 antibodies from the total IgG pool. In conclusion, RA patients remain positive for anti-hPAD4 antibodies over time and some patients who are initially anti-hPAD4 negative become positive later in the disease course. The anti-hPAD4 antibodies did not affect the enzymatic activity of hPAD4 when the small substrate N-α-Benzoyl-l-arginine ethyl ester was used. However, this finding may not exclude an effect of these autoantibodies on citrullination of protein substrates in RA