Distributed archive and single access system for accelerometric event data : a NERIES initiative

We developed a common access facility to homogeneously formatted accelerometric event data and to the corresponding sheet of ground motion parameters. This paper is focused on the description of the technical development of the accelerometric data server and the link with the accelerometric data explorer. The server is the third node of the 3-tier architecture of the distributed archive system for accelerometric data. The server is the link between the data users and the accelero- metric data portal. The server follows three main steps: (1) Reading and analysis of the end-user request; (2) Processing and converting data; and (3) Archiving and updating the accelerometric data explorer. This paper presents the description of the data server and the data explorer for accessing data

Damage Detection and Localisation Using Mode-Based Method and Perturbation Theory

International audienceIn this paper, the detection and the localization of a local perturbation are assessed by analysing the frequency changes only (fundamental mode and overtones). After describing the method used herein applied to the bending beam and based on the perturbation theory, experimental application to a 1D plexiglas beam is shown using frequency and modal analysis technique. The damage is considered as a local perturbation of Young's modulus. Finally, the localisation of damage is done using classical modal-based methods and perturbation theory. The frequency values are caught by the Random Decrement Technique applied to the time history vibrations for one sensor at the free extremity of the beam. Detection and localization are successful, even for small and transientchanges of the structure properties

Modal and thermal analysis of Les Arches unstable rock column (Vercors massif, French Alps)

A potentially unstable limestone column (∼1000 m3, Vercors, French Alps) delineated by an open rear fracture was continuously instrumented with two three-component seismic sensors from mid-May 2009 to mid-October 2011. Spectral analysis of seismic noise allowed several resonance frequencies to be determined, ranging from 6 to 21 Hz. The frequency domain decomposition (FDD) technique was applied to the ambient vibrations recorded on the top of the rock column. Three vibration modes were identified at 6, 7.5 and 9 Hz, describing the upper part of corresponding modal shapes. Finite element numerical modelling of the column dynamic response confirmed that the first two modes are bending modes perpendicular and parallel to the fracture, respectively, while the third one corresponds to torsion. Seismic noise monitoring also pointed out that resonance frequencies fluctuate with time, under thermomechanical control. For seasonal cycles, changes in frequency are due to the variations of the bulk elastic properties with temperature. At daily scale, increase in fundamental frequency with temperature has been interpreted as resulting from the rock expansion inducing a closure of the rear fracture rock bridges, hence stiffening the contact between the column and the rock mass. Conversely, the rock contraction induces a fracture opening and a decrease in resonance frequency. In winter, when the temperature drops below 0 ◦C, a dramatic increase in fundamental frequency is observed from 6 Hz to more than 25 Hz, resulting from ice formation in the fracture. During spring, the resonance frequency gradually diminishes with ice melting to reach the value measured before winter

Lptv Subspace Analysis of Wind Turbines Data

International audienceThe modal analysis of a wind turbine has been generally handled with the assumption that this structure can be accurately modeled as linear time-invariant. Such assumption may be misleading for stability analysis, especially, with the current development of very large wind turbines with complex dynamic behavior (nonlinearity, aeroelastic coupling). Therefore in this paper, the inherent periodically time-varying dynamics of wind turbines (and for rotating systems, in general) is taken into account. Recently a subspace algorithm for modal analysis of rotating systems has been proposed. It is tested on a simulated and real data from a wind turbine

Détection et localisation de changements dans une structure (application numérique et expérimentale)

La détection d'endommagements et de changements des propriétés élastiques dans des structures, utilisant les variations des paramètres dynamiques, fait l'objet d'une attention particulière depuis plusieurs années dans les domaines du génie mécanique et du génie civil. Le principe général repose sur le fait que la variation des propriétés physiques (e.g. rigidité, masse, module d'Young, conditions aux limites) entraîne une variation des caractéristiques dynamiques de la structure (e.g. fréquences de résonance, amortissements modaux et déformées modales). La présence d'endommagement provoque ainsi une diminution de la rigidité de la structure, c'est-à-dire une augmentation de sa flexibilité et de son amortissement que l'on retrouve dans la forme des modes et les valeurs des fréquences. Utilisant le changement de ces informations entre un état sain et un état endommagé, plusieurs méthodes non-destructives ont été proposées dans la littérature afin d'identifier et de localiser ces endommagements. Ces pratiques et ces activités sont d'une importance considérable puisqu'elles permettent en premier lieu d'anticiper et donc d'éviter des ruptures dans les structures, toujours catastrophiques, et plus généralement de mettre en place des plans de maintenance prédictives, en lien avec le suivi sur le long terme de leur intégrité (Structural Health Monitoring). Ces méthodes de surveillance se popularisent également du fait de la réduction des coûts des instrumentations, liés à l'apparition de nouveaux équipements à bas coût, ayant des performances satisfaisantes. L'objectif de ce travail est de tester les différentes solutions permettant la détection, la localisation et la quantification des changements dans des structures simples. Plusieurs méthodes ont été testées et une approche nouvelle a été proposée basée sur l'utilisation de la méthode des perturbations. Trois approches ont été suivies: une modélisation par éléments finis (analyse modale), une simulation numériques par éléments finis (analyse temporelle) et enfin des analyses expérimentales sur des poutres en Plexiglas au laboratoire, les trois volets de ce travail ayant permis de tester la sensibilité des méthodes non-destructives (NDE) globales et locales pour la détection et la localisation. Les changements ont été associés à une variation locale du module de Young (E), numériquement pour les solutions numériques et par chauffage local sur des sections de la poutre dans le volet expérimental. Dans tous les cas, nous sommes en situations réelles afin de proposer l'identification des caractéristiques modales par des méthodes opérationnelles (Operative Modal Analysis) telles que la méthode du décrément aléatoire et la méthode de décomposition dans le domaine fréquentiel (Frequency Domain Decomposition). Les résultats d'identification ont montré une très bonne corrélation entre les valeurs numériques et les valeurs expérimentales obtenues : fréquences de résonance et déformés modale. Pour identifier l'endommagement, les méthodes de localisation basées sur la courbure des déformées propres, la matrice de flexibilité, la courbure de flexibilité et enfin sur la méthode d'inversion des modes ont été employées. D'après les résultats obtenus, la méthode d'inversion se montre efficace dans le cas de variations modales faibles et transitoires, alors que la méthode de la courbure de flexibilité donne généralement de bons résultats et apparait robuste lorsque les variations sont plus prononcées.The detection of damage and changes in elastic properties of structures, using the variation of dynamic parameters, has been the subject of special attention for several years in the fields of mechanical and civil engineering. The general principle is based on the fact that the variation of physical properties (e.g. stiffness, mass, Young's modulus, boundary conditions) leads to a change in the dynamic characteristics of structures (e.g. resonance frequencies, modal damping and mode shapes). The presence of damage causes a decrease in the rigidity of structures, which give rise to an increase in flexibility and damping, which can be seen in mode shapes and frequency values. Using the change of this information between a healthy and damaged condition, several non-destructive methods have been proposed in the literature in order to identify and locate the damage. These practices and activities are of considerable importance. They allow us to anticipate and avoid breaks in structures, which are always catastrophic, and more generally, they allow us to establish the plans of a predictive maintenance, along with monitoring of the long-term of integrity (Structural Health monitoring). These monitoring methods are equally us popular because of the low cost of instrumentation, related to the appearance of new equipment at low cost, having the satisfactory performance. The objective of this work is to test different solutions, allow for detection, localization and quantification of changes in simple structures. Several methods have been tested and a new approach is proposed based on the use of the perturbation method. Three approaches are followed: finite element modeling (modal analysis), finite element numerical simulation (temporal analysis), and finally, experimental analysis of a Plexiglas beam in the laboratory. These three scopes of work have allowed us to test the sensitivity of global and local non-destructive methods (NDE) for detection and localization of damage. Changes associated with a local variation of Young's modulus (E) are tested numerically in modal and temporal analysis, and shown experimentally in local heating on the sections of beam. In all cases, we are in real life situations, where we identify modal characteristics by operational methods (Operative Modal Analysis) such as the random decrement technique and the method of decomposition in the frequency domain (Frequency Domain Decomposition). The results show a very good correlation between the numerical and experimental values obtained: resonant frequencies and mode shapes. For identifying damage, localization methods based on the curvature of mode shape, flexibility matrix, curvature of flexibility, and finally on the method of inversion of modes are employed. According to the results, the method of inversion proves effective in the case where modal variation is low and transient, whereas, the curvature of flexibility (ULS method) usually gives good results and appears robust when the changes are more pronounced.SAVOIE-SCD - Bib.électronique (730659901) / SudocGRENOBLE1/INP-Bib.électronique (384210012) / SudocGRENOBLE2/3-Bib.électronique (384219901) / SudocSudocFranceF

Horizontal Gene Transfer Regulation in Bacteria as a “Spandrel” of DNA Repair Mechanisms

Horizontal gene transfer (HGT) is recognized as the major force for bacterial genome evolution. Yet, numerous questions remain about the transferred genes, their function, quantity and frequency. The extent to which genetic transformation by exogenous DNA has occurred over evolutionary time was initially addressed by an in silico approach using the complete genome sequence of the Ralstonia solanacearum GMI1000 strain. Methods based on phylogenetic reconstruction of prokaryote homologous genes families detected 151 genes (13.3%) of foreign origin in the R. solanacearum genome and tentatively identified their bacterial origin. These putative transfers were analyzed in comparison to experimental transformation tests involving 18 different genomic DNA positions in the genome as sites for homologous or homeologous recombination. Significant transformation frequency differences were observed among these positions tested regardless of the overall genomic divergence of the R. solanacearum strains tested as recipients. The genomic positions containing the putative exogenous DNA were not systematically transformed at the highest frequencies. The two genomic “hot spots”, which contain recA and mutS genes, exhibited transformation frequencies from 2 to more than 4 orders of magnitude higher than positions associated with other genes depending on the recipient strain. These results support the notion that the bacterial cell is equipped with active mechanisms to modulate acquisition of new DNA in different genomic positions. Bio-informatics study correlated recombination “hot-spots” to the presence of Chi-like signature sequences with which recombination might be preferentially initiated. The fundamental role of HGT is certainly not limited to the critical impact that the very rare foreign genes acquired mainly by chance can have on the bacterial adaptation potential. The frequency to which HGT with homologous and homeologous DNA happens in the environment might have led the bacteria to hijack DNA repair mechanisms in order to generate genetic diversity without losing too much genomic stability

Accommodation cyclique du polyéthylène : expériences et modélisation thermo-viscoélastique non-linéaire fortement couplée

L'objectif est de prédire l'accommodation cyclique d'un polymère semi-cristallin en intégrant le couplage fort entre la mécanique et la thermique. Il s'agit de capter les deux échelles de temps liées à l'évolution de la déformation moyenne qui accompagne le cyclage et à la boucle stabilisée elle-même, avec des contributions énergétiques pertinentes, utilisables le cas échéant dans un critère de fatigue. Un premier travail avait été mené dans un cadre isotherme. L'étude expérimentale et théorique est ici étendue au cadre thermo-mécanique. Des essais de traction et cisaillement, réalisés par le LMGC de Montpellier, permettent d'accéder aux sources de chaleur. Ils sont confrontés à un modèle thermo-viscoélastique non-linéaire dans lequel le couplage est introduit via la thermo-élasticité (par la déformation volumique) et via la dissipation visqueuse (sur la base du principe d'équivalence temps-température). L'article présente les résultats en cisaillement

A Universal Bleeding Risk Score in Native and Allograft Kidney Biopsies: A French Nationwide Cohort Study

BackgroundThe risk of bleeding after percutaneous biopsy in kidney transplant recipients is usually low but may vary. A pre-procedure bleeding risk score in this population is lacking.MethodsWe assessed the major bleeding rate (transfusion, angiographic intervention, nephrectomy, hemorrhage/hematoma) at 8 days in 28,034 kidney transplant recipients with a kidney biopsy during the 2010-2019 period in France and compared them to 55,026 patients with a native kidney biopsy as controls.ResultsThe rate of major bleeding was low (angiographic intervention: 0.2%, hemorrhage/hematoma: 0.4%, nephrectomy: 0.02%, blood transfusion: 4.0%). A new bleeding risk score was developed (anemia = 1, female gender = 1, heart failure = 1, acute kidney failure = 2 points). The rate of bleeding varied: 1.6%, 2.9%, 3.7%, 6.0%, 8.0%, and 9.2% for scores 0 to 5, respectively, in kidney transplant recipients. The ROC AUC was 0.649 (0.634-0.664) in kidney transplant recipients and 0.755 (0.746-0.763) in patients who had a native kidney biopsy (rate of bleeding: from 1.2% for score = 0 to 19.2% for score = 5).ConclusionsThe risk of major bleeding is low in most patients but indeed variable. A new universal risk score can be helpful to guide the decision concerning kidney biopsy and the choice of inpatient vs. outpatient procedure both in native and allograft kidney recipients

DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France

We evaluated the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid-19 severity was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti-CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39–3.02, p < 0.001) with Covid-19 severity, whereas interferon indicated a decreased risk (OR = 0.42, 95%CI = 0.18–0.99, p = 0.047). This pooled-analysis confirms an increased risk of severe Covid-19 in patients on anti-CD20 therapies and supports the protective role of interferon

4MOST: Project overview and information for the First Call for Proposals

We introduce the 4-metre Multi-Object Spectroscopic Telescope (4MOST), a new high-multiplex, wide-field spectroscopic survey facility under development for the four-metre-class Visible and Infrared Survey Telescope for Astronomy (VISTA) at Paranal. Its key specifications are: a large field of view (FoV) of 4.2 square degrees and a high multiplex capability, with 1624 fibres feeding two low-resolution spectrographs ($R = \lambda/\Delta\lambda \sim 6500$), and 812 fibres transferring light to the high-resolution spectrograph ($R \sim 20\,000$). After a description of the instrument and its expected performance, a short overview is given of its operational scheme and planned 4MOST Consortium science; these aspects are covered in more detail in other articles in this edition of The Messenger. Finally, the processes, schedules, and policies concerning the selection of ESO Community Surveys are presented, commencing with a singular opportunity to submit Letters of Intent for Public Surveys during the first five years of 4MOST operations