The internationalisation of Spanish SMEs : main developments and their determinants

Artículo de revist

Del lugar al tiempo en adverbios de la documentación notarial leonesa

El autor presenta un estudio sobre la evolución de los adverbios de lugar y tiempo a través de la documentación notarial recogida en las Colecciones Diplomáticas de los Monasterios de Sahagún y Carrizo durante los siglos IX al XII

Os olhos de Renata. Anedota duma paciente sobrevivente

Renata había sido doblemente mastectomizada. Las heridas quirúrgicas habían cicatrizado, ya no tenía los puntos de sutura, sin embargo, las cicatrices aún tenían ese color rosáceo típico de las heridas que llevan poco tiempo cerradas. Ese color “rosa vulnerable”. Tres veces fueron los intentos de querer marcharse, tres los amagos de partida y en las tres ocasiones le salvaron la vida aquella misma tarde, en un intervalo de dos o tres horas. La ausencia de pechos en Renata, así como su alopecia secundaria a la quimioterapia y los recientes tatuajes por causa de las quemaduras de las palas del desfibrilador, justo en el lugar donde se encontraban aquellas heridas rosas, daban a Renata un aspecto andrógino desconcertante, grotesco. ¿Podríamos contarle alguna vez que había estado a punto de… irse…, tres…, veces? Podríamos decirle alguna vez con algunas risas que era una mujer muy terca y obstinada?Renata had been doubly mastectomized. Surgical wounds had scarred, no longer had the stitches, however, the scars still had that typical pink color of the wounds that have only recently closed. That color “vulnerable-pink”. Three were her attempts two leave, three the feints of leaving and on all three occasions they saved her life that afternoon, in an interval of two or three hours. The absence of breasts in Renata, and her alopecia secondary to chemotherapy and her recent tattoos caused by burns of the defibrillator paddles, right there, in the place where those roses wounds were, gave Renata a bewildering androgynous look, grotesque . Could we ever tell her that she had been about to leave ... ... three ... times? Could we ever tell her with some laughs how head-strong she was, how stubborn?Renata tinha sido mastectomizada duplamente. As feridas cirúrgicas tinhan curado, já não tinha os pontos de sutura, no entanto, as cicatrizes ainda tinhan aquela cor-de-rosa típico das feridas que só recentemente fechadas. Que a cor “rosa vulnerável”. Três foram as tentantivas dela querendo deixar, três as fintas de sair embora e em todas as três ocasiões salvaram a sua vida, essa mesma tarde, em um intervalo de duas ou três horas. A ausência de seios en Renata, e sua alopecia secundária à quimioterapia, e tatuagens recentes causado por queimaduras as pás do desfibrilador, bem no lugar onde essas feridas rosas eram, deu Renata uma aparência andrógina grotescamente desconcertante. Poderíamos alguma vez dizer que ela estava prestes a sair ... ... três ... vezes? Poderíamos alguma vez dizer com algumas risadas que era uma mulher muito teimosa

Effectiveness of physical therapy in axillary web syndrome after breast cancer: a systematic review and meta-analysis

The axillary web syndrome (AWS) is a surgical breast cancer sequel that limits the functionality of the patient and delays the protocol times of application of cancer treatments. This implies a long period of discomfort and limitations for the user. Objective: To investigate the different physiotherapy treatments for the AWS and how effective they are. Methods: A systematic review based on PRISMA protocol and registered in PROSPERO (CRD42021281354) was conducted. The research was performed using PubMed, Scopus, CINAHL, PEDro, and Web of Science databases during January 2022 and March 2022. All randomized controlled trials and controlled clinical trials were included in this review. Results: A total of 188 articles were identified, with 9 studies selected for the systematic review. These studies basically propose treatments based on exercises and stretching, manual therapy, and the combination of manual therapy and exercises. Conclusions: Exercise and stretching are the most effective therapies within the field of physiotherapy for the rehabilitation of axillary web syndrome. They restore range of motion faster, reduce pain, improve quality of life, and reduce disabilities. Manual therapy, scar massage, and myofascial release could help improve outcomes but with worse results. The meta-analysis conclusion is that pain is the only outcome with a significant reduction after the application of physiotherapy treatments − 0.82 [− 1.67; 0.03]. This conclusion is drawn from the only three studies with small sample sizesFunding for open access publishing: Universidad de Cádiz/CBUA This study was funded by the University of Málaga through a predoctoral grant support to JBGR, a PhD student at the university

Standardization Framework for Sustainability from Circular Economy 4.0

The circular economy (CE) is widely known as a way to implement and achieve sustainability, mainly due to its contribution towards the separation of biological and technical nutrients under cyclic industrial metabolism. The incorporation of the principles of the CE in the links of the value chain of the various sectors of the economy strives to ensure circularity, safety, and efficiency. The framework proposed is aligned with the goals of the 2030 Agenda for Sustainable Development regarding the orientation towards the mitigation and regeneration of the metabolic rift by considering a double perspective. Firstly, it strives to conceptualize the CE as a paradigm of sustainability. Its principles are established, and its techniques and tools are organized into two frameworks oriented towards causes (cradle to cradle) and effects (life cycle assessment), and these are structured under the three pillars of sustainability, for their projection within the proposed framework. Secondly, a framework is established to facilitate the implementation of the CE with the use of standards, which constitute the requirements, tools, and indicators to control each life cycle phase, and of key enabling technologies (KETs) that add circular value 4.0 to the socio-ecological transition

Eco‐Holonic 4.0 Circular Business Model to Conceptualize Sustainable Value Chain Towards Digital Transition

The purpose of this paper is to conceptualize a circular business model based on an Eco-Holonic Architecture, through the integration of circular economy and holonic principles. A conceptual model is developed to manage the complexity of integrating circular economy principles, digital transformation, and tools and frameworks for sustainability into business models. The proposed architecture is multilevel and multiscale in order to achieve the instantiation of the sustainable value chain in any territory. The architecture promotes the incorporation of circular economy and holonic principles into new circular business models. This integrated perspective of business model can support the design and upgrade of the manufacturing companies in their respective industrial sectors. The conceptual model proposed is based on activity theory that considers the interactions between technical and social systems and allows the mitigation of the metabolic rift that exists between natural and social metabolism. This study contributes to the existing literature on circular economy, circular business models and activity theory by considering holonic paradigm concerns, which have not been explored yet. This research also offers a unique holonic architecture of circular business model by considering different levels, relationships, dynamism and contextualization (territory) aspects

Quantitative and qualitative methods of evaluating response to biologics in severe asthma patients: Results from a real-world study

[EN] Asthma is a complex major noncommunicable disease affecting around 333 million people worldwide, both children and adults.New biological therapies for treating severe asthma have remarkably improved disease management. Notwith-standing, one remaining crucial problem is evaluating the response to these treatments. Therefore, adequate measurement of the response to biologics in a holistic manner that integrates clinical variables of interest and quality of life is needed, particularly in identifying super-responder patients (SR). Menzies-Gow et al went more profound in the concept and proposed a consensus to evaluate remission.Instituto de Salud Carlos III (ISCIII); European Union -Next Generation EU; Junta de Castilla y Leó

Formación en programas de Intercomparación-Proficiency Tests: una potente herramienta de control de calidad de los laboratorios

Memoria ID-0003. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2016-2017

Pruebas de aptitud y competencia en el laboratorio para los alumnos de Ciencias Químicas y Biotecnología. Normas UNE-EN ISO/IEC 17043 y UNE-EN ISO/IEC 17025

Memoria ID-0153. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2015-2016