Die Selbstkonzept-Entwicklung im Erwachsenenalter in der Sicht dreier Alters-Generations-Gruppen von Lehrern

Die kognizierten Selbstkonzept-Entwicklungen von Lehrern aus drei Alters-/Generationsgruppen (25-35, 40-50, 55-65 Jahre) wurden empirisch untersucht. Bei 182 Lehrern aller Schularten wurde ein faktoriell gewonnenes Selbstratingverfahren angewendet, das sowohl die Selbsteinschätzung als auch die Beurteilung der Selbstkognitionen fremder Personen (Fremd-Selbsteinschätzung) zu den Bereichen "Allgemeines, positives, leistungsbezogenes Selbstbild", "Soziale Kontaktfähigkeit" und "Anpassung an soziale Normen" erlaubt. Die Hypothesen, dass es zu einer fortschreitenden Realbild-Idealbild-Diskrepanzreduktion im Selbstbild der Lehrer kommt, fanden nur teilweise empirische Unterstützung

The Association of Mid-Regional Pro-Adrenomedullin and Mid-Regional Pro-Atrial Natriuretic Peptide with Mortality in an Incident Dialysis Cohort

High levels of the plasma peptides mid-regional pro-adrenomedullin (MR-proADM) and mid-regional pro-atrial natriuretic peptide (MR-proANP) are associated with clinical outcomes in the general population. Data in patients with chronic kidney disease are sparse. We therefore investigated the association of MR-proANP and MR-proADM levels with all-cause and cardiovascular (CV) mortality, CV events and peripheral arterial disease in 201 incident dialysis patients of the INVOR-Study prospectively followed for a period of up to more than 7 years. The overall mortality rate was 43%, thereof 43% due to CV events. Both baseline MR-proANP and MR-proADM were associated with higher risk of all-cause (HR = 1.44, p = 0.001 and HR = 1.32, p = 0.002, respectively) and CV mortality (HR = 1.75, p<0.001 and HR = 1.41, p = 0.007, respectively) after adjustment for age, sex, previous CV events, diabetes mellitus and time-dependent type of renal replacement therapy. We then stratified patients in high risk (both peptides in the upper tertile), intermediate risk (only one of the two peptides in the upper tertile) and low risk (none in the upper tertile). Although demographic, clinical and laboratory variables were similar among the intermediate and high risk group, to be with both parameters in the upper tertile was associated with a 3-fold higher risk for all-cause (HR = 2.87, p<0.001) and CV mortality (HR = 3.58, p = 0.001). In summary, among incident dialysis patients MR-proANP and MR-proADM were shown to be associated with all-cause and CV mortality, with the highest risk when both parameters were in the upper tertiles

Association of HbA1c values with mortality and cardiovascular events in O

Abstract Background: Improved glycemic control reduces complications in patients with diabetes mellitus (DM). However, it is discussed controversially whether patients with diabetes mellitus and end-stage renal disease benefit from strict glycemic control

Association of HbA1c Values with Mortality and Cardiovascular Events in Diabetic Dialysis Patients. The INVOR Study and Review of the Literature

BACKGROUND: Improved glycemic control reduces complications in patients with diabetes mellitus (DM). However, it is discussed controversially whether patients with diabetes mellitus and end-stage renal disease benefit from strict glycemic control. METHODS: We followed 78 patients with DM initiating dialysis treatment of the region of Vorarlberg in a prospective cohort study applying a time-dependent Cox regression analysis using all measured laboratory values for up to more than seven years. This resulted in 880 HbA(1c) measurements (with one measurement every 3.16 patient months on average) during the entire observation period. Non-linear P-splines were used to allow flexible modeling of the association with mortality and cardiovascular disease (CVD) events. RESULTS: We observed a decreased mortality risk with increasing HbA(1c) values (HR = 0.72 per 1% increase, p = 0.024). Adjustment for age and sex and additional adjustment for other CVD risk factors only slightly attenuated the association (HR = 0.71, p = 0.044). A non-linear P-spline showed that the association did not follow a fully linear pattern with a highly significant non-linear component (p = 0.001) with an increased risk of all-cause mortality for HbA(1c) values up to 6-7%. Causes of death were associated with HbA(1c) values. The risk for CVD events, however, increased with increasing HbA(1c) values (HR = 1.24 per 1% increase, p = 0.048) but vanished after extended adjustments. CONCLUSIONS: This study considered the entire information collected on HbA(1c) over a period of more than seven years. Besides the methodological advantages our data indicate a significant inverse association between HbA(1c) levels and all-cause mortality. However, for CVD events no significant association could be found

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

Background: Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (<5 years) and older people (≥65 years). A global report of the monthly activity of these viruses is needed to inform public health strategies and programmes for their control. Methods: In this systematic analysis, we compiled data from a systematic literature review of studies published between Jan 1, 2000, and Dec 31, 2017; online datasets; and unpublished research data. Studies were eligible for inclusion if they reported laboratory-confirmed incidence data of human infection of influenza virus, respiratory syncytial virus, parainfluenza virus, or metapneumovirus, or a combination of these, for at least 12 consecutive months (or 52 weeks equivalent); stable testing practice throughout all years reported; virus results among residents in well-defined geographical locations; and aggregated virus results at least on a monthly basis. Data were extracted through a three-stage process, from which we calculated monthly annual average percentage (AAP) as the relative strength of virus activity. We defined duration of epidemics as the minimum number of months to account for 75% of annual positive samples, with each component month defined as an epidemic month. Furthermore, we modelled monthly AAP of influenza virus and respiratory syncytial virus using site-specific temperature and relative humidity for the prediction of local average epidemic months. We also predicted global epidemic months of influenza virus and respiratory syncytial virus on a 5° by 5° grid. The systematic review in this study is registered with PROSPERO, number CRD42018091628. Findings: We initally identified 37 335 eligible studies. Of 21 065 studies remaining after exclusion of duplicates, 1081 full-text articles were assessed for eligibility, of which 185 were identified as eligible. We included 246 sites for influenza virus, 183 sites for respiratory syncytial virus, 83 sites for parainfluenza virus, and 65 sites for metapneumovirus. Influenza virus had clear seasonal epidemics in winter months in most temperate sites but timing of epidemics was more variable and less seasonal with decreasing distance from the equator. Unlike influenza virus, respiratory syncytial virus had clear seasonal epidemics in both temperate and tropical regions, starting in late summer months in the tropics of each hemisphere, reaching most temperate sites in winter months. In most temperate sites, influenza virus epidemics occurred later than respiratory syncytial virus (by 0·3 months [95% CI −0·3 to 0·9]) while no clear temporal order was observed in the tropics. Parainfluenza virus epidemics were found mostly in spring and early summer months in each hemisphere. Metapneumovirus epidemics occurred in late winter and spring in most temperate sites but the timing of epidemics was more diverse in the tropics. Influenza virus epidemics had shorter duration (3·8 months [3·6 to 4·0]) in temperate sites and longer duration (5·2 months [4·9 to 5·5]) in the tropics. Duration of epidemics was similar across all sites for respiratory syncytial virus (4·6 months [4·3 to 4·8]), as it was for metapneumovirus (4·8 months [4·4 to 5·1]). By comparison, parainfluenza virus had longer duration of epidemics (6·3 months [6·0 to 6·7]). Our model had good predictability in the average epidemic months of influenza virus in temperate regions and respiratory syncytial virus in both temperate and tropical regions. Through leave-one-out cross validation, the overall prediction error in the onset of epidemics was within 1 month (influenza virus −0·2 months [−0·6 to 0·1]; respiratory syncytial virus 0·1 months [−0·2 to 0·4]). Interpretation: This study is the first to provide global representations of month-by-month activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus. Our model is helpful in predicting the local onset month of influenza virus and respiratory syncytial virus epidemics. The seasonality information has important implications for health services planning, the timing of respiratory syncytial virus passive prophylaxis, and the strategy of influenza virus and future respiratory syncytial virus vaccination. Funding: European Union Innovative Medicines Initiative Respiratory Syncytial Virus Consortium in Europe (RESCEU)

How 3 Age-Generation-Groups of Teachers Perceive the Development of Self-Concept in Adulthood

Mummendey HD, Albers G, Sturm G. Die Selbstkonzept-Entwicklung im Erwachsenenalter in der Sicht dreier Alters-Generations-Gruppen von Lehrern. Psychologie in Erziehung und Unterricht. 1985;32(2):126-135

Die Selbstkonzept-Entwicklung im Erwachsenenalter in der Sicht dreier verschiedener Alters- / Generations-Gruppen

Mummendey HD, Albers G, Sturm G. Die Selbstkonzept-Entwicklung im Erwachsenenalter in der Sicht dreier verschiedener Alters- / Generations-Gruppen. Bielefelder Arbeiten zur Sozialpsychologie, 109. Bielefeld: Universität Bielefeld, Fak. für Soziologie; 1984

How 3 Age-Generation-Groups of Teachers Perceive the Development of Self-Concept in Adulthood

Mummendey HD, Albers G, Sturm G. Die Selbstkonzept-Entwicklung im Erwachsenenalter in der Sicht dreier Alters-Generations-Gruppen von Lehrern. Psychologie in Erziehung und Unterricht. 1985;32(2):126-135

Die Selbstkonzept-Entwicklung im Erwachsenenalter in der Sicht dreier verschiedener Alters- / Generations-Gruppen

Mummendey HD, Albers G, Sturm G. Die Selbstkonzept-Entwicklung im Erwachsenenalter in der Sicht dreier verschiedener Alters- / Generations-Gruppen. Bielefelder Arbeiten zur Sozialpsychologie, 109. Bielefeld: Universität Bielefeld, Fak. für Soziologie; 1984

ncbench/ncbench-workflow: v1.0.2

&lt;h2&gt;&lt;a href="https://github.com/ncbench/ncbench-workflow/compare/v1.0.1...v1.0.2"&gt;1.0.2&lt;/a&gt; (2023-11-14)&lt;/h2&gt; &lt;h3&gt;Performance Improvements&lt;/h3&gt; &lt;ul&gt; &lt;li&gt;update to dna-seq-benchmark 1.8.5 (&lt;a href="https://github.com/ncbench/ncbench-workflow/issues/35"&gt;#35&lt;/a&gt;) (&lt;a href="https://github.com/ncbench/ncbench-workflow/commit/ba713e5b4aeb97ed72d77287f6c07a3dd8f09973"&gt;ba713e5&lt;/a&gt;)&lt;/li&gt; &lt;/ul&gt