Del complejo militar romano al monacato altomedieval : aproximación a las transformaciones del espacio interior galaico entre los siglos I y IX d. C. a partir de los asentamientos de A Cidadela (Sobrado dos Monxes, A Coruña)

Jornadas de Jóvenes en Investigación Arqueológica, JIA (3as : 5-7 de mayo 2010 : Universitat Autònoma de Barcelona). Sesión 3. Indicios arqueológicos de la vertebración del territorio y su poblamiento desde época ibérica hasta la Tardoantigüedad en la Península Ibérica.A Cidadela es, a día de hoy, uno de los más emblemáticos yacimientos de la arqueología gallega. Conocido desde inicios del siglo XX, sus excavaciones modernas cumplirán el próximo año su treinta aniversario. Con todo, siguen existiendo no pocos puntos oscuros en su historia: no hemos alcanzado a comprender el porqué de un asentamiento militar romano en la región; su cronología de ocupación sigue siendo, cuanto menos, confusa; la investigación apenas se ha ocupado del entorno del yacimiento; y las fases germánica y altomedieval siguen sumidas en la penumbra. Es nuestro objetivo arrojar alguna luz sobre estas y otras problemáticas en base al trabajo de un grupo interdisciplinar.A Cidadela is, nowadays, one of the most emblematic sites of Galician archaeology. Well-known since the beginnings of XX century, the modern excavations are going to achieve next year their thirtieth anniversary. Even so, there are still several points in its history not entirely resolved: we have not got to understand the reason for a roman military settlement in the region; the chronology of its occupation is, at least, confusing; the research has barely paid attention to the environment of the site; and the Germanic and Early Medieval periods are still plunged in the half-light. It is our aim to throw light on these and other problems based on the work of an interdisciplinary group

Tunable structure and properties of segmented thermoplastic polyurethanes as a function of flexible segment

Segmented thermoplastic polyurethanes (PUs) were synthetized using macrodiols with different functional groups (carbonate, ester, and /or ether) as a segment with a molar mass of 1000 and 2000 g/mol, and 4,4'-diphenylmethane diisocyanate (MDI) and 1,4-butanediol as a rigid segment. The polyurethanes obtained reveal a wide variation of microphase separation degree that is correlated with mechanical properties and retention of tensile properties under degradation by heat, oil, weather, and water. Different techniques such as differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), Fourier transform infrared (FTIR), and synchrotron small-angle X-ray scattering (SAXS) were used to determine rigid-flexible segments' phase behaviour. Retention of tensile properties determines the stability of the samples under different external factors. This work reveals that pure polycarbonate-based macrodiols induce the highest degree of phase miscibility, better tensile properties, hardness shore A, and retention of tensile properties under external agents

Maintenance of chondrocyte phenotype during expansion on PLLA microtopographies

[EN] Articular chondrocytes are difficult to grow, as they lose their characteristic phenotype following expansion on standard tissue culture plates. Here, we show that culturing them on surfaces of poly(L-lactic acid) of well-defined microtopography allows expansion and maintenance of characteristic chondrogenic markers. We investigated the dynamics of human chondrocyte dedifferentiation on the different poly(L-lactic acid) microtopographies by the expression of collagen type I, collagen type II and aggrecan at different culture times. When seeded on poly(L-lactic acid), chondrocytes maintained their characteristic hyaline phenotype up to 7days, which allowed to expand the initial cell population approximately six times without cell dedifferentiation. Maintenance of cell phenotype was afterwards correlated to cell adhesion on the different substrates. Chondrocytes adhesion occurs via the (51) integrin on poly(L-lactic acid), suggesting cell-fibronectin interactions. However, (21) integrin is mainly expressed on the control substrate after 1day of culture, and the characteristic chondrocytic markers are lost (collagen type II expression is overcome by the synthesis of collagen type I). Expanding chondrocytes on poly(L-lactic acid) might be an effective solution to prevent dedifferentiation and improving the number of cells needed for autologous chondrocyte transplantation.The support received from the European Research Council (ERC 306990) and the UK EPSRC (EP/P001114/1) is acknowledged. J.L.G.R. acknowledges support of the Spanish Ministry of Economy and Competitiveness (MINECO) through the project MAT2016-76039-C4-1 (including the FEDER financial support). CIBER-BBN is an initiative funded by the VI National R&D&i Plan 2008-2011, Iniciativa Ingenio 2010, Consolider Programme, CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund.Costa Martínez, E.; González García, C.; Gómez Ribelles, JL.; Salmerón Sánchez, M. (2018). Maintenance of chondrocyte phenotype during expansion on PLLA microtopographies. Journal of Tissue Engineering. 9. https://doi.org/10.1177/2041731418789829S9Hunziker, E. B. (1999). Articular cartilage repair: are the intrinsic biological constraints undermining this process insuperable? Osteoarthritis and Cartilage, 7(1), 15-28. doi:10.1053/joca.1998.0159Benya, P. D., Padilla, S. R., & Nimni, M. E. (1978). Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture. Cell, 15(4), 1313-1321. doi:10.1016/0092-8674(78)90056-9Mayne, R., Vail, M. S., Mayne, P. M., & Miller, E. J. (1976). 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Biomaterials, 27(7), 1043-1053. doi:10.1016/j.biomaterials.2005.07.032Benya, P. D., Brown, P. D., & Padilla, S. R. (1988). Microfilament modification by dihydrocytochalasin B causes retinoic acid-modulated chondrocytes to reexpress the differentiated collagen phenotype without a change in shape. Journal of Cell Biology, 106(1), 161-170. doi:10.1083/jcb.106.1.161Brown, P. D., & Benya, P. D. (1988). Alterations in chondrocyte cytoskeletal architecture during phenotypic modulation by retinoic acid and dihydrocytochalasin B-induced reexpression. Journal of Cell Biology, 106(1), 171-179. doi:10.1083/jcb.106.1.171Martínez, E. C., Hernández, J. C. R., Machado, M., Mano, J. F., Ribelles, J. L. G., Pradas, M. M., & Sánchez, M. S. (2008). Human Chondrocyte Morphology, Its Dedifferentiation, and Fibronectin Conformation on Different PLLA Microtopographies. Tissue Engineering Part A, 14(10), 1751-1762. doi:10.1089/ten.tea.2007.0270Hernández Sánchez, F., Molina Mateo, J., Romero Colomer, F. J., Salmerón Sánchez, M., Gómez Ribelles, J. L., & Mano, J. F. (2005). Influence of Low-Temperature Nucleation on the Crystallization Process of Poly(l-lactide). Biomacromolecules, 6(6), 3283-3290. doi:10.1021/bm050323tZhang, T., Gong, T., Xie, J., Lin, S., Liu, Y., Zhou, T., & Lin, Y. (2016). Softening Substrates Promote Chondrocytes Phenotype via RhoA/ROCK Pathway. ACS Applied Materials & Interfaces, 8(35), 22884-22891. doi:10.1021/acsami.6b07097Schuh, E., Hofmann, S., Stok, K. S., Notbohm, H., Müller, R., & Rotter, N. (2011). The influence of matrix elasticity on chondrocyte behavior in 3D. Journal of Tissue Engineering and Regenerative Medicine, 6(10), e31-e42. doi:10.1002/term.501Parreno, J., Bianchi, V. J., Sermer, C., Regmi, S. C., Backstein, D., Schmidt, T. A., & Kandel, R. A. (2018). Adherent agarose mold cultures: An in vitro platform for multi-factorial assessment of passaged chondrocyte redifferentiation. 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The development of information literacy in early childhood education teachers. A study from the perspective of the education center's character

The development of the digital competence is one of the current challenges of the educational community. Specifically, the area of information literacy is presented as a main pillar for the subsequent optimal development of a digital teaching competence. Based on this, the present article aims to evaluate the area of information literacy in practicing teachers from Early Childhood Education (N=57). A descriptive and inferential quantitative analysis was made for this piece of work in order to analyze the perceptions of the teachers towards this area, the accomplishment of the t-student test for the comparison of means between teachers of public and private with state-funded financial support centers and the application of a linear regression model that allows to predict the information literacy through the variable “education center”. The results obtained reflected an optimal level of perceptions as for the information area, regardless of the type of school, as well as the possible prediction, regarding the school typology, of some information literacy variablesPeer Reviewe

A new expanded modelling approach for investigating the bioprotective capacity of Latilactobacillus sakei CTC494 against Listeria monocytogenes in ready-to-eat fish products

Understanding the role of food-related factors on the efficacy of protective cultures is essential to attain optimal results for developing biopreservation-based strategies. The aim of this work was to assess and model growth of Latilactobacillus sakei CTC494 and Listeria monocytogenes CTC1034, and their interaction, in two different ready-to-eat fish products (i.e., surimi-based product and tuna pâté) at 2 and 12 °C. The existing expanded Jameson-effect and a new expanded Jameson-effect model proposed in this study were evaluated to quantitatively describe the effect of microbial interaction. The inhibiting effect of the selected lactic acid bacteria strain on the pathogen growth was product dependent. In surimi product, a reduction of lag time of both strains was observed when growing in coculture at 2 °C, followed by the inhibition of the pathogen when the bioprotective L. sakei CTC494 reached the maximum population density, suggesting a mutualism-antagonism continuum phenomenon between populations. In tuna pâté, L. sakei CTC494 exerted a strong inhibition of L. monocytogenes at 2 °C (<0.5 log increase) and limited the growth at 12 °C (<2 log increase). The goodness-of-fit indexes indicated that the new expanded Jameson-effect model performed better and appropriately described the different competition patterns observed in the tested fish products. The proposed expanded competition model allowed for description of not only antagonistic but also mutualism-based interactions based on their influence on lag time

Evaluación de la implantación de la metodología Design Thinking en una asignatura de proyectos

[EN] This paper discusses the experience of introducing the Design Thinking methodology in course Project Lab (LPRO) in academic year 2015/2016. LPRO is a course in the syllabus of the degree in Telecommunication Technologies Engineering taught at University of Vigo, Spain. First, the target course is introduced, as it can be considered to be a unique course in a similar way to the Design Thinking methodology applied. Then, we discuss how Design Thinking was approached in three from the nineteen projects carried out during the mentioned academic year, paying special attention to the restrictions related to the time teachers could devote to interact with students in actual lectures. Finally, some results and concluding remarks are offered.[ES] En esta comunicación relataremos la experiencia desarrollada durante el curso 2015/2016 al implantar la metodología Design Thinking en la asignatura Laboratorio de Proyectos (LPRO) impartida en el Grado en Ingeniería de Tecnologías de Telecomunicación de la Universidad de Vigo. Para ello presentaremos la asignatura, dado que se trata de una asignatura singular dentro del plan de estudios de esta titulación de grado, al igual que la metodología Design Thinking. Posteriormente explicaremos cómo hemos introducido dicha metodología en tres de los diecinueve proyectos llevados a cabo en la asignatura, sobre todo teniendo en cuenta las restricciones de horas presenciales dedicadas al trabajo en clase con el profesor. Finalmente presentaremos los resultados y conclusiones extraídos de esta experiencia.Costa Montenegro, E.; Díaz Otero, F.; Caeiro Rodríguez, M.; Cuiñas Gómez, I.; Mariño Espiñeira, P.; Fernández Iglesias, M. (2016). Evaluación de la implantación de la metodología Design Thinking en una asignatura de proyectos. En In-Red 2016. II Congreso nacional de innovación educativa y docencia en red. Editorial Universitat Politècnica de València. https://doi.org/10.4995/INRED2016.2016.4357OC