A Single-centre, Before-After Study of the Short- and Long-term Efficacy of Narivent® in the Treatment of Nasal Congestion

Objective:Nasal congestion is a common symptom in allergic and nonallergic rhinitis, rhinosinusitis and nasal polyposis. The present study evaluated the clinical effectiveness of Narivent®, an osmo..

The Gaia-ESO Survey: dynamics of ionized and neutral gas in the Lagoon nebula (M8)

We present a spectroscopic study of the dynamics of the ionized and neutral gas throughout the Lagoon nebula (M8), using VLT/FLAMES data from the Gaia-ESO Survey. We explore the connections between the nebular gas and the stellar population of the associated star cluster NGC6530. We characterize through spectral fitting emission lines of H-alpha, [N II] and [S II] doublets, [O III], and absorption lines of sodium D doublet, using data from the FLAMES/Giraffe and UVES spectrographs, on more than 1000 sightlines towards the entire face of the Lagoon nebula. Gas temperatures are derived from line-width comparisons, densities from the [S II] doublet ratio, and ionization parameter from H-alpha/[N II] ratio. Although doubly-peaked emission profiles are rarely found, line asymmetries often imply multiple velocity components along the line of sight. This is especially true for the sodium absorption, and for the [O III] lines. Spatial maps for density and ionization are derived, and compared to other known properties of the nebula and of its massive stars 9 Sgr, Herschel 36 and HD 165052 which are confirmed to provide most of the ionizing flux. The detailed velocity fields across the nebula show several expanding shells, related to the cluster NGC6530, the O stars 9 Sgr and Herschel 36, and the massive protostar M8East-IR. The origins of kinematical expansion and ionization of the NGC6530 shell appear to be different. We are able to put constrains on the line-of-sight (relative or absolute) distances between some of these objects and the molecular cloud. The large obscuring band running through the middle of the nebula is being compressed by both sides, which might explain its enhanced density. We also find an unexplained large-scale velocity gradient across the entire nebula. At larger distances, the transition from ionized to neutral gas is studied using the sodium lines.Comment: 26 pages, 31 figures, accepted on Astronomy and Astrophysics journa

Calcitonin free oat-cell carcinoma of the thyroid gland

Two cases of primary oat-cell carcinoma of thyroid, in a 63-year-old woman and a 73-year-old man, are described. Case 1 was a compound tumour with the oat-cell component merging with a papillary component. Both tumours, in addition to histological features consistent with oat-cell carcinoma, showed immunohistochemical positivity with anti-chromagranin A and anti-synaptophysin antisera. Negative results were obtained when anti-calcitonin and anti-thyroglobulin antisera were employed. Using in situ hybridization, chromogranin A and B messenger RNAs were localized with biotinylated oligonucleotide probes. In contrast, with in situ hybridization, no localization for calcitonin messenger RNA was seen using radioactive and biotinylated probes. It is concluded that these calcitonin-free, small-cell carcinomas should be considered separately from medullary thyroid carcinomas and be regarded as a distinct entity, probably the thyroid equivalent of oat-cell carcinomas of the lung.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47516/1/428_2005_Article_BF01600144.pd

Factorization of the Universal R-matrix for Uq(sl^2)U_q(\hat{sl}_2)

The factorization of the universal R-matrix corresponding to so called Drinfeld Hopf structure is described on the example of quantum affine algebra $U_q(\hat{sl}_2)$. As a result of factorization procedure we deduce certain differential equations on the factors of the universal ${\cal R}$-matrix, which allow to construct uniquely these factors in the integral form.Comment: 28 pages, LaTeX 2.09 using amssym.def and amssym.te

Characterization of the Ferrara animal PET scanner

A dedicated small animal PET scanner, YAPPET, was designed and built at Ferrara University. Each detector consists of a 20� 20 matrix of 2� 2� 30 mm 3 YAP:Ce finger-like crystals glued together and directly coupled to a Hamamatsu position sensitive photomultiplier. The scanner is made from four detectors positioned on a rotating gantry at a distance of 7:5 cm from the center and the field of view (FOV) is 4 cm both in the transaxial direction and in the axial direction. The system operates in 3D acquisition mode. The performance parameters of YAPPET scanner such as spatial, energy and time resolution, as well as its sensitivity and counting rate have been determined. The average spatial resolution over the whole FOV is 1:8 mm at FWHM and 4:2 mm at FWTM. The sensitivity at the center is 640 cps=mCi: r 2002 Elsevier Science B.V. All rights reserved. PACS: 87.59.Wb; 87.59.Q

Appropriateness of frequent use of emergency departments: A retrospective analysis in Rome, Italy

Background: Frequent users (FUs) are patients who repeatedly and inappropriately visit the emergency department (ED) for low-grade symptoms that could be treated outside the hospital setting. This study aimed to investigate the phenomenon of the FU in Rome by profiling such users and analyzing ED attendance by FUs. Methods: The analysis was carried out for attendance in 2021 at 15 EDs in the Local Health Authority Roma 1 geographical area. A digital app collected data, including information on the following variables: number of attendance, demographic characteristics, emergency medical service (EMS) usage, triage code, and appropriateness of attendance. COVID-19 diagnosis was also studied to analyze any possible influence on ED attendance. Differences between FUs and non-FUs were investigated statistically by t-test and chi-square test. Univariate analysis and multivariable logistic regression were performed to analyze the associated factors. Results: A total of 122,762 ED attendance and 89,036 users were registered. The FU category represented 2.9% of all users, comprising 11.9% of total ED attendance. There was a three times higher frequency of non-urgent codes in attendance of FU patients (FU: 9.7%; non-FU: 3.2%). FUs were slightly more likely to have used the EMS (13.6% vs. 11.4%) and had a lower frequency of appropriate ED attendance (23.8% vs. 27.0%). Multivariate logistic analysis confirmed a significant effect of triage code, gender, age, EMS usage, and COVID-19 diagnosis for the appropriateness of attendance. The results were statistically significant (p < 0.001). Conclusion: The FU profile describes mostly non-urgent and inappropriate attendance at the ED, including during the COVID-19 pandemic. This study represents an important tool for strengthening preventive policies outside the hospital setting. The Italian National Recovery and Resilience Plan represents an excellent opportunity for the development of new strategies to mitigate the phenomenon of FUs

The Gaia-ESO Survey: Tracing interstellar extinction

Large spectroscopic surveys have enabled in the recent years the computation of three-dimensional interstellar extinction maps thanks to accurate stellar atmospheric parameters and line-of-sight distances. Such maps are complementary to 3D maps extracted from photometry, allowing a more thorough study of the dust properties. Our goal is to use the high-resolution spectroscopic survey Gaia-ESO in order to obtain with a good distance resolution the interstellar extinction and its dependency as a function of the environment and the Galactocentric position. We use the stellar atmospheric parameters of more than 5000 stars, obtained from the Gaia-ESO survey second internal data release, and combine them with optical (SDSS) and near-infrared (VISTA) photometry as well as different sets of theoretical stellar isochrones, in order to calculate line-of-sight extinction and distances. The extinction coefficients are then compared with the literature to discuss their dependancy on the stellar parameters and position in the Galaxy. Within the errors of our method, our work does not show that there is any dependence of the interstellar extinction coefficient on the atmospheric parameters of the stars. We do not find any evidence of the variation of E(J-H)/E(J-K) with the angle from the Galactic centre nor with Galactocentric distance. This suggests that we are dealing with a uniform extinction law in the SDSS ugriz bands and the near-IR JHKs bands. Therefore, extinction maps using mean colour-excesses and assuming a constant extinction coefficient can be used without introducing any systematic errors.Comment: 13 pages, 14 figures, 1 Appendix accepted for publication in Astronomy&Astrophysic

The Chandra survey of the COSMOS field II: source detection and photometry

The Chandra COSMOS Survey (C-COSMOS) is a large, 1.8 Ms, Chandra program, that covers the central contiguous ~0.92 deg^2 of the COSMOS field. C-COSMOS is the result of a complex tiling, with every position being observed in up to six overlapping pointings (four overlapping pointings in most of the central ~0.45 deg^2 area with the best exposure, and two overlapping pointings in most of the surrounding area, covering an additional ~0.47 deg^2). Therefore, the full exploitation of the C-COSMOS data requires a dedicated and accurate analysis focused on three main issues: 1) maximizing the sensitivity when the PSF changes strongly among different observations of the same source (from ~1 arcsec up to ~10 arcsec half power radius); 2) resolving close pairs; and 3) obtaining the best source localization and count rate. We present here our treatment of four key analysis items: source detection, localization, photometry, and survey sensitivity. Our final procedure consists of a two step procedure: (1) a wavelet detection algorithm, to find source candidates, (2) a maximum likelihood Point Spread Function fitting algorithm to evaluate the source count rates and the probability that each source candidate is a fluctuation of the background. We discuss the main characteristics of this procedure, that was the result of detailed comparisons between different detection algorithms and photometry tools, calibrated with extensive and dedicated simulations.Comment: Accepted for publication in The Astrophysical Journal Supplement Serie

Avaliação da composição química do bolo elaborado com farinha de feijão branco.

O objetivo deste trabalho foi avaliar a composição centesimal e os teores de açúcares totais, sacarose, pH e acidez total de um bolo preparado, a partir da substituição parcial de farinha de trigo pela farinha de feijão branco.CONAFE