10 research outputs found
Nonlinear time-history analysis of a base-isolated RC building in Shanghai founded on soft soil
A 6-story RC building with base isolation using rubber bearings and viscous dampers has been recently built in Shanghai.
Since the building is founded on soft soil, concern regarding base isolation suitability arose; even the Chinese design code does not recommend this solution for soft soil. To clarify this issue, nonlinear time-history analyses are carried out for a number of natural and artificial seismic inputs that represent the site seismicity, accounting for the soil conditions. The relevance of soil-structure interaction is discussed and some simulations are performed. Adequacy of base isolation is assessed both in the superstructure and the isolation layer. In the superstructure, appropriateness is judged in terms of reduction of interstory drift, absolute acceleration and shear force. In isolators, correctness is evaluated in terms of axial force, torsion angle and lateral displacement; prescriptions of Chinese and European regulations are considered. The major conclusion is that base isolation of ordinary mid-height RC buildings founded on soft soil can perform satisfactorily in medium seismicity regions.Postprint (published version
Suitability of seismic isolation for buildings founded on soft soil. Case study of a RC building in Shanghai
Base (seismic) isolation is a promising technology for seismic protection of buildings and other constructions. Nowadays, it is accepted that such a technique is efficient and reliable; however, it has two major limitations: soft foundation soil, and tall buildings. The first issue restrains the seismic isolation spreading, given that soft soil is frequent in densely populated areas, and usually such a soil type concentrates the highest seismicity levels. This paper aims to contribute to demonstrating that base isolation, if properly implemented, can be suitable for soft soil. A representative case study is analyzed: a 6-story reinforced concrete (RC) building with base isolation that has recently been built in Shanghai. Since the building is founded on soft soil, concern regarding base isolation suitability arose; even the Chinese design code does not recommend this solution for soft soil. To clarify this issue, non-linear time-history analyses are carried out for a number of natural and artificial seismic inputs that represent the site seismicity; the superstructure behavior is linear, while nonlinearities are concentrated in the isolation layer. The adequacy of base isolation is assessed in the superstructure (in terms of reduction of interstory drift, absolute acceleration and shear force) and in the isolation layer (in terms of axial force, torsion angle and shear strain). The relevance of soil–structure interaction is discussed. The behavior when the mechanical parameters of the isolation units have experienced important changes is also analyzed. The major conclusion is that base isolation of ordinary mid-height RC buildings founded on soft soil can perform satisfactorily in medium seismicity regions.Peer ReviewedPostprint (published version
Nonlinear time-history analysis of a base-isolated RC building in Shanghai founded on soft soil
A 6-story RC building with base isolation using rubber bearings and viscous dampers has been recently built in Shanghai.
Since the building is founded on soft soil, concern regarding base isolation suitability arose; even the Chinese design code does not recommend this solution for soft soil. To clarify this issue, nonlinear time-history analyses are carried out for a number of natural and artificial seismic inputs that represent the site seismicity, accounting for the soil conditions. The relevance of soil-structure interaction is discussed and some simulations are performed. Adequacy of base isolation is assessed both in the superstructure and the isolation layer. In the superstructure, appropriateness is judged in terms of reduction of interstory drift, absolute acceleration and shear force. In isolators, correctness is evaluated in terms of axial force, torsion angle and lateral displacement; prescriptions of Chinese and European regulations are considered. The major conclusion is that base isolation of ordinary mid-height RC buildings founded on soft soil can perform satisfactorily in medium seismicity regions
Transfer Parameter Analysis of Chloride Ingress into Concrete Based on Long-Term Exposure Tests in China’s Coastal Region
Chloride penetration resistance is one of the most important performance measures for the evaluation of the durability of concrete under a chloride environment. Due to differences in theory and experimental conditions, the durability index (chloride diffusion coefficient) obtained from laboratory accelerated migration tests cannot reflect the real process of chloride ingress into concrete in the natural environment. The difference in test methods must be considered and the transfer parameter kt should be introduced into the service life prediction model when the test results of accelerated methods are used. According to the test data of coastal exposure in South China, the attenuation rule of the chloride diffusion coefficient of different cement-based materials changed with time and was analyzed in this paper. Based on the diffusion coefficient–time curve, the theoretical natural diffusion coefficients of 28 d and 56 d were deduced, which were compared with the chloride diffusion coefficients obtained from the non-steady-state rapid migration method (RCM) at the same age. Therefore, the transfer parameter kt that expounds the relationship between concrete resistance to chloride permeability under a non-stationary electrical accelerated state and natural diffusion in the marine environment can be calculated; thus, the RCM testing index can be used to evaluate the long-term performance of the concrete structure in the marine environment. The results show that the value of kt was related to environmental conditions, test methods, and binder systems
Influence of the Coupling Action of Flexural Load and Freezing–Thawing on the Chloride Diffusion of Marine High-Performance Concrete
The chloride diffusion of marine high-performance concrete under a couple of actions, flexural load and freezing–thawing, was investigated by a fast freezing and thawing test in NaCl solution. Concrete specimens of 100 × 100 × 515 mm were tested under bending load and 300 freeze–thaw cycles under the stress levels of 15%, 30%, and 50% of the ultimate fracture modulus. The change in the microstructure of the concrete was analyzed by SEM and MIP. The results indicated that the chloride diffusion coefficient of concrete under the coupling effect of flexural load and freezing–thawing or simple flexural load increased with the increasing in the flexural stress level, and the chloride diffusion coefficient was approximately exponential to the flexural stress level, as D = 0.8777e1.668σ for a couple of actions of flexural load and freezing–thawing, and D = 0.8336e1.3231σ for a simple flexural load. The resistance ability of concrete to chloride diffusion was reduced by the freezing–thawing procedures, the resisted ability dropped more severely under a couple of actions of flexural load and freezing–thawing than simple flexural load at the same stress level. Micro-cracks at the interfacial transition zone between the aggregate and the paste matrix in concrete was induced under a couple of actions of flexural load and freezing–thawing, which increased the average pore size and total pore volume, resulting in the modification of the pore size distribution in the concrete. The influence of a couple of actions of flexural load and freezing–thawing on the concrete was greater than that of simple flexural load
IL-27 enhances innate immunity of human pulmonary fibroblasts and epithelial cells through upregulation of TLR4 expression
Simple design method of structure with metallic yielding dampers based on elastic–plastic response reduction curve
2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema
Background:
We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angioedema: a current state-of-the-art review: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema.
Objective:
To update the International Consensus Algorithm for the Diagnosis, Therapy and Management of Hereditary Angioedema (circa 2010).
Methods:
The Canadian Hereditary Angioedema Network (CHAEN)/Réseau Canadien d'angioédème héréditaire (RCAH) http://www.haecanada.com and cosponsors University of Calgary and the Canadian Society of Allergy and Clinical Immunology (with an unrestricted educational grant from CSL Behring) held our third Conference May 15th to 16th, 2010 in Toronto Canada to update our consensus approach. The Consensus document was reviewed at the meeting and then circulated for review.
Results:
This manuscript is the 2010 International Consensus Algorithm for the Diagnosis, Therapy and Management of Hereditary Angioedema that resulted from that conference.
Conclusions:
Consensus approach is only an interim guide to a complex disorder such as HAE and should be replaced as soon as possible with large phase III and IV clinical trials, meta analyses, and using data base registry validation of approaches including quality of life and cost benefit analyses, followed by large head-to-head clinical trials and then evidence-based guidelines and standards for HAE disease management.Medicine, Department ofMedicine, Faculty ofPediatrics, Department ofNon UBCReviewedFacult
Performance of the CMS hadron calorimeter with cosmic ray muons and LHC beam data
The CMS Hadron Calorimeter in the barrel, endcap and forward regions is fully commissioned. Cosmic ray data were taken with and without magnetic field at the surface hall and after installation in the experimental hall, hundred meters underground. Various measurements were also performed during the few days of beam in the LHC in September 2008. Calibration parameters were extracted, and the energy response of the HCAL determined from test beam data has been checked