17 research outputs found
Romance of Leadership as a Leader Emergence Predictor
- Author
- Publication venue
- AFIT Scholar
- Publication date
- 01/01/2008
- Field of study
The purpose of this paper is to examine whether a link between romance of leadership and leader emergence exists. To test this proposition, a sample population was drawn from a military leadership development program for senior enlisted personnel. The school\u27s 406 students were broken into 28 separate groupings called flights , each led by an instructor. The data for this study was obtained by administering the Romance of Leadership Scale (RLS) and observing leader emergence within the individual flights over a six-week period. The hypothesis that individuals who exhibit a high romance of leadership will be more likely to emerge as a leader was supported (p \u3c .05) in the case of peer ratings. The assertion that locus of control will moderate the relationship between romance of leadership and leader emergence received strong support in the case of instructor ratings (p \u3c .001) and partial support in the case of peer ratings (p \u3c .06)
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study
- Author
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C.
- Adamsson Richard O.
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S.
- Aguirre-Bermeo Hernan
- Aisa Tharwat M.
- Aisiku Imo
- Ajetunmobi Olaitan O.
- Aker Mustafa
- Akyol Onat O.
- Al Dorzi Hasan M.
- Al Jabbary Ahmed S.
- Albaiceta Guillermo M.
- Albarrak Mohamad M.
- Albiero Daniela
- Alda Rosa S.
- Alejandro Risso V.
- Alexander Peter
- Algaba Ángela
- Aliaga Felipe A.
- Alisasis Alain U.
- Allan Russell M.
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier G.
- Altaf Wahid
- Alvarez António M.
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Abdellatif Benslama Mourad
- An Youzhong
- Andersen Finn H.
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Antonelli Massimo M.
- Antônio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M.
- Araujo Ana M.
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D.
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E.
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio C.
- Bailey Irene M.
- Bailey Mathew B.
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie M.
- Barberet Guillaume
- Baron Rebecca M.
- Baronia Arvind K.
- Barratt-Due Andreas
- Barros Filipa M.
- Barros Nelson C.
- Batra Hitesh
- Battle Ceri E.
- Bauer Philippe R.
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu H.
- Beegle Scott H.
- Beitler Jeremy R.
- Bellani Giacomo
- Bellani Giacomo
- Beloncle Francois
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans Frantz
- Besset Sebastien L.
- Bettini Lisandro R.
- Beuret Pascal
- Bezzi Marco G.
- Bhardwaj Vallish K.
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Biondi Rodrigo S.
- Biscione Roberto R.
- Bisso Mariano Carboni
- Black Colin S.
- Blakeman Thomas C.
- Bolon Stefan
- Borello Silvina A.
- Borotto Erika E.
- Botteri Marco
- Bouchoucha Slaheddine
- Boukhazna Messabi
- Bouw Maria J.
- Boyd Owen
- Bramall Jon
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M.
- Briquet Anais
- Brito Vania A.
- Brizuela Matias
- Brochard Laurent
- Brochard Laurent
- Broman Lars M.
- Brown Samuel M.
- Browne Troy S.
- Bruhn Alejandro R.
- Brunettini Barbara
- Bruns Monique M.
- Buensuseso Juan A.
- Bugedo Guillermo
- Buise Marc P.
- Bulpa Pierre A.
- Bumbasierevic Vesna
- Bumbasirevic Vesna
- Burtenshaw Andrew J.
- Burtin Philippe
- Buzancais Gautier
- Béduneau Gaetan
- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
- Carbayo-Gorriz Cecilia
- Cardonnet Luis P.
- Careless Jon P.
- Carpentier Dorothée
- Carreño Nicolás G.
- Carteaux Guillaume
- Casalena Paolo
- Casement Jonathan
- Castro Alejandro G.
- Castro Silvia
- Catorze Nuno T.
- Cazorla-Barranquero Francisca G.
- Ceniceros-Barros Alexandra
- Cereijo Enrique
- Cerny Vladimir
- Cerrato Valeria I.
- Cervantes Mavy Ramirez
- Cesar Palazon Sanchez
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman Rhiannon
- Chau Simon K.
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Cheng Meisy Perez
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry Shazia
- Christiansen Aage
- Cimic Nedim
- Cinnella Gilda
- Cirone Rob
- Citalán Johanna E.
- Claraco-Vega Luis M.
- Clarkson Kevin
- Clarkson Kevin P.
- Claverias Laura
- Cohen Jason E.
- Cole Jade M.
- Collins Daniel V.
- Collyer Thomas
- Colombo Riccardo
- Combaux Daniele M.
- Combes Alain
- Cooper Raphael
- Coppadoro Andrea
- Corneci Dan E.
- Cortegiani Andrea
- Cortez Cesar A.
- Coxo Cristina M.
- Cracchiolo Andrea N.
- Cranshaw Julius H.
- Crapelli Giulia
- Crouch Daniel R.
- Crova Philippe J.
- Csabi Peter
- Curley Gerard
- Curto Elena Gallego
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric
- Daubin C. dric
- Daviaud Fabrice
- Davies Kyle G.
- Dawson Heidi
- de Cima-Iglesias Sara
- de Gordoa Laura Ortiz-Ruiz
- de Haro Candelaria
- de Pablo Raul
- de Prost Nicolas
- Dean Michael N.
- Declercq Pierre-Louis M.
- Dector Dulce
- Dector Dulce M.
- Deicas Alberto
- del Carmen Lorente Maria
- Dellamonica Jean
- Dellera Christian
- Delsing Angela
- Demirkiran Oktay
- Demoule Alexandre
- Dempsey Ged
- Dendane Tarek
- Depuydt P.
- Depuydt Pieter
- Derman Suleyman S.
- di Tomasso Nora N.
- di Yu D.
- Diaz-Rodriguez Esther
- Dive Alain M.
- Dixit Subhal B.
- Do Vale Fernandes Antero
- Dolva Merete S.
- Donnelly Adrian
- Dowling Anna T.
- Doyen Denis
- Dres Martin
- Dreyer Kyle R.
- Dunne Eimhin S.
- Dupont Herve
- Duranteau Jacques
- Dwyer Rory
- Démpaire Gabriel
- Ebeid Alejandro
- Elatrous Souheil
- Elisabet Garcia M.
- Elkhayari Mina
- Ellis Helen E.
- Elmasri Mary
- Erbabacan Emre
- Eriksson Karin E.
- Esteban Andres
- Estenssoro Elisa
- Esteve Francisco
- Estilita Joana M.
- Estrella Claudia R.
- Ezzouine Hanane
- Fan Eddy
- Fan Eddy
- Fartoukh Muriel
- Farías Pamela A.
- Fawkes Danielle A.
- Ferguson Andrew
- Ferguson Niall D.
- Fernandez Adriana M.
- Fernandez Ruben O.
- Fierro Jonathan M.
- Floris Leda
- Follin Arnaud
- Fontenele Danielle C.
- Formenti Paolo
- Forteza Catalina
- Fossali Tommaso
- Foti Giuseppe
- Franco Nieves
- França Ana G.
- Frati Elena
- Frendl Gyorgy
- Frigyik Aniko D.
- Fusari Maurizio
- Futami Satoru
- Gally Josette
- Ganesan Deeban
- Gao Yan
- Gao Yuan N.
- Garcia Patricio H.
- Gattinoni Luciano
- Gazenkampf Andrey A.
- Gelée Bruno
- George Fernando G.
- Ghazi Mohammed
- Gianinetto Hernan
- Giarratano Antonino
- Gillis Sarah
- Girgin Nermin Kelebek
- Gjedsted Jakob
- Glietsch Rita
- Goldgran-Toledano Dany
- Goligher Ewan C.
- Gomaa Dina
- Gomes Rui M.
- Gomez Pablo E.
- Gomez-Flores Saira S.
- Gonz Á Lez Raquel Montiel
- Gonzalez Daniel R.
- Gonzalez Marcos
- González Rojas Manuel A.
- González-Salamanca Ángela
- Gonçalves Claudio H.
- Goodson Jennifer C.
- Gordo Federico
- Gosselin Ryan J.
- Goubaux Bernard
- Graziani Romano
- Grelon Fabien
- Griffin Ruth O.
- Grigoriev Evgeny
- Grijalba Carolina Quintana
- Grissom Colin K.
- Gritsan Alexey I.
- Grubissich Nicolas
- Gueret Renaud M.
- Gurjar Mohan
- Guttormsen Anne B.
- Guérin Claude
- Gómez Pilar Ricart Aroa
- Hacking Danielle J.
- Haddad Youssef
- Hadfield Dan
- Hagan Samantha J.
- Han Hui
- Han Yi
- Hang Ai Y.
- Hanlon Gabrielle C.
- Harasawa Tomofumi
- Harrois Anatole
- Hashemian S. M.
- Hashemian Seyed Mohammadreza
- Hashida Tomoaki
- He Zhenyang
- Hedlund Lars
- Heidari Farshad
- Heines Serge J.
- Helleberg Johan
- Henderson Galen
- Herbrecht Jean-Etienne
- Hermosa Cecilia
- Hessell Robert J.
- Heunks Leo M.
- Higashijima Ushio
- Hirata Akira
- Holzgraefe Bernhard
- Honda Hiroyuki
- Honrubia Teresa
- Hopf Hans-Bernd F.
- Hopkins Phil
- Hormis Anil P.
- Hou Peter C.
- Hou Sen-Kuang
- Hraiech Sami
- Hua Ma X.
- Huang Qing Q.
- Huang Xiao B.
- Huerta Francisco P.
- Huff Nidhi G.
- Humphreys Sally K.
- Hunt Anna
- Hurtado Javier
- Hutchison Robyn A.
- Hutton Paula J.
- Ibañez-Santacruz Marcos
- Ichikado Kazuya
- Ilutovich Santiago
- Imai Hiroshi
- Imma Vallverdu P.
- Imperio María C.
- Insaurralde Carolina S.
- Inskip Deborah M.
- Ioannou Nicholas
- Iotti Giorgio A.
- Irvine Donald A.
- Ismail Dina
- Ismail Mehvish
- Ito Fumihito
- Izawa Masayo
- Jaafar Rola F.
- Jakubowska Karina
- Jamaati Hamidreza
- Jarquin-Badiola Yves D.
- Jassal Mandeep
- Javeed Areej
- Javier-Blanco
- Jhamatthew Thomas Rajeev R.
- Jiang Liangyan
- Jibaja Manuel
- Jimenez Antonio G.
- Jochmans S. bastien
- Jog Sameer A.
- Jovanovic Bojan
- Judy Claine
- Jurado M. . Teresa
- Kadaba Varsha
- Kajtor Istvan
- Kakar Vivek
- Kalaitzis Evangelos
- Kalkoff Michael
- Kamel Ghassan
- Kameyama Yoshinobu
- Kamoun Salma
- Kander Thomas
- Kannan Santhana G.
- Kansuke-Koyama
- Kashiwa Yozo
- Kedelv Hans
- Kennedy Barry
- Khebbeb Samy
- Kheir Fayez
- Kheir Fayez M.
- Kimura Hiroyasu
- Kiourtzieva Ellada V.
- Kitch Barrett T.
- Knapman Karl M.
- Knoll Jenny
- Knowles Serena
- Kol Mark R.
- Kong Jing
- Kraßler Jens
- Krstevski Amanda
- Kulkarni Shreedhar
- Kumar Alek
- Kurahashi Kiyoyasu
- Kusumoto Kohei
- Laake Jon H.
- Laake Jon Henrik
- Labarca Eduardo F.
- Laffey John
- Laffey John G.
- Laffey John G.
- Lamb Keith D.
- Lanspa Michael J.
- Larsson Anders
- Larsson Niklas
- le Moal Charlene
- Lebbinck Herve
- Lee Jarone
- Leemann-Refondini Corinne
- Lemiale Virginie
- Lemus Jordana S.
- Leon Yoshido Hector H.
- Li Bin
- Li Qingdong
- Li Qiong J.
- Li Wenwen
- Li Xiao L.
- Li Xinyu
- Li Yimin
- Li Yuan Y.
- Li-Xin Zhou
- Liew Kong Y.
- Ling Long L.
- Liu Haitao
- Liu Jian
- Liu Jing L.
- Liu Ling
- Llano Miguel
- Llinares Moya David D.
- Lohner Ralph
- Loiacono Flavia A.
- Lombardo Andrea
- Lopez Esther Bermejo
- Lopez-Delgado Juan C.
- Lora Fredy S.
- Lora Pilar
- Lorente Jose A.
- Losada Elena Perez
- Lovazzano Pablo
- Lu Weihua
- Lu Yuanhua
- Luis Palazon Sanchez Eugenio
- Luo Xiaoming
- Lynch Joan M.
- López-Messa Juan B.
- Maazouzi Wajdi
- MacFadyen Rosaleen
- MacFie Caroline C.
- Madotto Fabiana
- Maeyama Hiroki N.
- Maghrabi Khalid A.
- Magret Monica
- Mahto Heera L.
- Mancebo Jordi
- Manoharan Venika
- Marcos Diego Pastor
- Marcu Alexandra
- Maria Villa
- Marin Julien
- Marin Maria C.
- Martinez Felipe T.
- Martinho Aurelia M.
- Marum Susan M.
- Massa Eleni V.
- Mataloun Sergio
- Matamis Dimitrios
- Matsumoto Shuhei
- Mattei Alessia
- May Martin M.
- McArthur Colin
- McAuley Daniel F.
- McAuley Daniel F.
- McAuley Danny
- McCalman Katie H.
- McKechnie Stuart
- McKee Raymond
- McKenna Toni E.
- McLeod Alex
- McNamee Lia
- McNicholas Bairbre
- Meaney Edel A.
- Meco Basak Ceyda
- Meersseman Philippe
- Mehta Sangeeta
- Mejia Francisco Javier Flores
- Mellis Clare
- Memon Mohammedfaruk
- Mercat Alain
- Mesar Tomaz
- Messias António M.
- Messika Jonathan
- Meybohm Patrick
- Michel Philippe
- Millar Rebecca T.
- Miller Jennene J.
- Miller Russel R.
- Mirabella Lucia
- Miryam-Prieto-González
- Mizuguchi Ichiko
- Mochizuki Katsunori
- Mohr Nicholas M.
- Mojoli Francesco
- Moles Silvia Iglesias
- Molin Alexandre
- Montanha Gustavo M.
- Monteiro Jorge M.
- Montero Laura Alvarez
- Montes Oscanoa Fredy A.
- Monti Giacomo
- Montini Luca M.
- Moock Marcelo
- Morin Anna-Karin
- Mortaza Satar
- Morton Alex
- Mouloudi Eleni K.
- Mukkera Satyanarayana Reddy
- Mustafa Ghanem M.
- Muthuchellappan Radhakrishnan
- Myra-Rinia
- Máca Jan
- Nagy Eva O.
- Nakamura Tomoyuki
- Namih Miriam
- Nassar Antonio P.
- Nasu Michitaka
- Navalpotro Miguel Angel Blasco
- Navarra Leanlove
- Navarro Gonzalo
- Neal John
- Negoita Silvius Ioan
- Newby Lynette
- Nichol Alistair
- Nielsen Jonas
- Niimi Daisuke
- Nin Nicolas
- Nin Nicolás
- Nishikawa Erin
- Nitta Kenichi
- Nobrega Danielle
- Noremark Kim Andre L.
- Nunci Lordian
- Nunes Silvia L.
- Nutt Christopher
- Nuñez Edgardo
- Nygren Ingela
- O'Croinin Donall
- O'Kane Sinead C.
- O'Muircheartaigh Aogan C.
- O'Neill Orla
- Occhipinti Giovanna
- Oetting Trevor W.
- Ogino Yasuaki
- Oikonomou Marina A.
- Okuda Nao
- Oldroyd Matthew G.
- Olga Moreno F.
- Oliveira Bruno S.
- Ortiz Claudia A.
- Osman Emilio M.
- Oss Peteris
- Ouanes Islem
- Ourailogloy Vasilis
- Owens Robert L.
- Ozcelik Menekse
- Palaniswamy Vijayanand
- Palma Daniela M.
- Palmese Salvatore
- Palo Jose Emmanuel
- Panarello Giovanna
- Panwar Rakshit
- Papanikolaou Metaxia N.
- Papavasilopoulou Theonymfi G.
- Papazian Laurent
- Papurica Marius
- Para Luis Herrera
- Parhar Ken
- Parotto Matteo
- Pasanting-Lim Rossini Abbie B.
- Patroniti Nicolò
- Pattarino Pierpaolo Terragni Ilaria
- Pecci Elisabetta
- Pellegrini Carlos A.
- Pelletier Nicolas
- Pellicer Ana M.
- Penuelas Oscar
- Pereira Carlos S.
- Perez Cesar P.
- Perez Manuel P.
- Persson Linnea
- Pesenti Antonio
- Pg Hj Ismail Dk Maizatul Aiman B.
- Pham T. i
- Pham T. i
- Pham Tai
- Phan Nga T.
- Piacentini Enrique A.
- Pillai Suresh
- Pintado Maria C.
- Piquilloud Lise
- Piras Claudio
- Pittini Gustavo
- Plotnikow Gustavo A.
- Poblano Manuel
- Poli Michela M.
- Pota Vincenzo
- Pozo Norberto C.
- Pozzi Matteo
- Preez Pieter D.
- Pronovost Antoine
- Protti Alessandro
- Protti Alessandro
- Qin Bingyu
- Qin Junping
- Qin Shu H.
- Qin Tie H.
- Qiu Haibo
- Raaijmakers Monique
- Rafael S. nchez I.
- Raimondi Ferdinando
- Raj Ashok S.
- Ramakrishnan Nagarajan
- Ramesh Venkatapura J.
- Ramirez-Alfaro Christian M.
- Ramirez-Gutierrez Alvaro
- Rampinelli Adenilton M.
- Ranero Jorge Luis
- Ranieri Marco
- Raponi Francesco
- Recio Noelia N.
- Reschreiter Henrik
- Reske Andreas W.
- Reuter Danielle
- Reynolds Claire
- Rezoagli Emanuele
- Rhayakar Rachana V.
- Rialp Gemma
- Richecoeur Jack R.
- Ricome Sylvie
- Rigaud Jean-Philippe
- Rios Fernando
- Riss Katharina C.
- Rittayamai Nuttapol
- Roberts Brigit L.
- Robine Adrien
- Robles Joanne B.
- Roche-Campo Ferran
- Rodgers Helen J.
- Rodriguez Lucia L.
- Rodriguez Ruben
- Rosa Jonas I.
- Roser Tomas P.
- Rossi Anna
- Roux Damien
- Rubenfeld Gordon
- Rugonfalvi Szabolcs
- Ruiz Silvia Rodriguez
- Ruiz-Aguilar Antonio L.
- Rylander Christian C.
- Ryosuke Sekine
- Sabelnikovs Olegs
- Sable Safal D.
- Saenz María G.
- Saez Alejandro A.
- Sagar Sudha V.
- Saito Koji
- Saito Shigeki
- Salahuddin Nawal
- Salas Javier E.
- Sales Vanessa M.
- Samkaoui Nacer
- Sanchez Roberto Jimenez
- Sanchez-Hurtado Luis A.
- Sanchez-Medina Jorge R.
- Sandesc Dorel
- Santoli Francesco L.
- Santos Cristina
- Sauvadet Elise P.
- Savioli Monica
- Scafetti Sergio
- Schiavone Vincenzo
- Schiavoni Lorenzo
- Schiöler Fredrik
- Schlichting Adam B.
- Schmidt Marcello
- Schneider Francis
- Schomer Ashley
- Schouten Jeroen A.
- Schuetz Michael
- Schultz Marcus J.
- Schäfer Susanne
- Scott Christopher J.
- Seasman Colette
- Seethala Raghu
- Sellors Gareth P.
- Seoane-Quiroga Leticia
- Serra Carolina
- Serra Isabel M.
- Setten Mariano G.
- Seven Aylin
- Shah Bhagyesh
- Shao Huanzhang
- Shen Juanhong
- Shenoy Anitha
- Sher Sara
- Shimizu Kazuyoshi
- Shin-Nunomiya
- Shindhe Suresh
- Shinn John O.
- Shiozaki Kyoko
- Silesky Jimenez Juan I.
- Silesky Juan
- Sim Malcolm
- Simon Philipp
- Simonis Fabienne D.
- Sivashanmugavel Mageswaran
- Sjøbø Brit Å.
- Sklienka Peter
- Slutsky Arthur S.
- Smith Mark J.
- Smith Oliver
- Soler Juan Alfonso
- Solis-Quesada Jaime E.
- Sotillo Diaz Juan Carlos J.
- Sottiaux T.
- Souissi Asma Ben
- Spadaro Savino
- Srinivasa Latha
- Stamou Electra E.
- Staudinger Thomas
- Stephenson Lorraine
- Stewart Richard
- Stigler William
- Strauch Ulrich
- Sula Hektor
- Sun Renhua
- Surbatovic Maja
- Susana-Temprano
- Suzuki Hiroyuki
- Symmonds Sophie
- Szakmany Tamas
- Sánchez Rocío Manzano
- Sánchez-Ballesteros Jesús
- Søreide Eldar
- Tabhan Edgardo
- Tabhan Edgardo E.
- Tainter Christopher
- Takaba Akihiro
- Takada Tadaaki
- Takagi Shunsuke
- Tallet Alfonso Alec A.
- Tan Beatriz C.
- Tanaka Hiroyuki
- Tang Rui
- Tapponnier Romain
- Tarantino Fabio
- Terzi Nicolas
- Theresa Uhc Mother
- Thibault Sandrine
- Thompson B. Taylor
- Thompson Marlus M.
- Tibblin Anna Oscarsson
- Tinnirello Andrea
- Tiribelli Norberto
- Todeschini Manuel
- Tomescu Dana R.
- Toribio D. Á Cil Parrilla
- Toth-Tarsoly Piroska
- Treanor Nuala
- Trinder T. John
- Trinidad Olivia A.
- Tulaimat Aiman
- Twohey Linda
- Uchiyama Akinori
- Ueda Takeshi
- Ueno Keiko
- Umbrello Michele
- Unnikrishnan Ramesh
- Uppalapati Aditya
- van Haren Frank
- van Haren Frank
- van Wezel Hellen M.
- Vargas Monica P.
- Vascotto Ettore R.
- Vasquez Daniela N.
- Vega Luis D.
- Veljovic Milic
- Venti Aaron
- Vercueil Andre
- Vermassen Joris
- Verstraete Rik
- Villagomez Asisclo
- Villagomez Asisclo J.
- Villamagua Boris G.
- Villar Veronica
- Vinzio Mauricio
- Virgilio Corcoles G.
- Vitale Michela N.
- Volta Carlo A.
- Wang Chunting
- Wang Hua X.
- Wang Shou H.
- Wang Wei
- Warren Jessica
- Watanabe Eizo
- Watt Philip
- Welters Ingeborg D.
- Wenham Tim
- Wessbergh Joanna
- Whitehead Christina
- Willett Emma L.
- Williams Alexandra J.
- Williams Karen E.
- Wise Matt P.
- Wittebole Xavier
- Wong Helen S.
- Woods Paul W.
- Wrathall David W.
- Wrigge Hermann
- Wu Ya Q.
- Xin-Hua Qiang
- Xu Yonghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L.
- Yeatts Dale J.
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste Luis J.
- Zacharas Giannis A.
- Zacharowski Kai D.
- Zani Gianluca
- Zantua Kim S.
- Zazu Alan
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé O.
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao Huiying
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa C.
- Zhou Suming
- Zhu Bao H.
- Zhu Wei H.
- Zogheib Elie H.
- Ñamendys-Silva Silvio A.
- Ünal Necmettin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe
Statistical Mechanics of Classical and Disordered Systems
- Author
- Adrien Schertzer
- Aernout C. D. van Enter
- Alessandra Faggionato
- Charles M. Newman
- Christof Külske
- Daniel L. Stein
- Dmitry Ioffe
- Erwin Bolthausen
- Francesco Guerra
- Gayrard Véronique
- Gayrard-Troy Véronique,
- Goetz Kersting
- Jiri Cerny
- Lily Z. Wang
- Lisa Hartung
- Louis-Pierre Arguin
- Marius A. Schmidt
- Nicola Kistler
- Pietro Caputo
- Reza Gheissari
- Roberto Persechino
- Vitali Wachtel
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 16/09/2019
- Field of study
International audienc
Immunocompromised patients with acute respiratory distress syndrome: Secondary analysis of the LUNG SAFE database
- Author
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C.
- Adamsson Richard
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S.
- Aguirre-Bermeo Hernan
- Aisa Tharwat
- Aisiku Imo
- Ajetunmobi Olaitan
- Aker Mustafa
- Akyol Onat
- Al Dorzi Hasan M.
- Al Jabbary Ahmed
- Albaiceta Guillermo
- Albarrak Mohamad M.
- Albiero Daniela
- Alda Rosa S.
- Alejandro Risso V.
- Alexander Peter
- Alfonso Alec A. Tallet
- Algaba Ángela
- Aliaga Felipe A.
- Alisasis Alain
- Allan Russell
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier
- Altaf Wahid
- Alvarez António
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Mourad
- An Youzhong
- Andersen Finn
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Antonelli Massimo
- Antonelli Massimo
- Antônio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M.
- Araujo Ana
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D.
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio
- Bailey Irene M.
- Bailey Mathew B.
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie
- Barberet Guillaume
- Baron Rebecca
- Baronia Arvind K.
- Barratt-Due Andreas
- Barros Filipa
- Barros Nelson C.
- Batra Hitesh
- Battle Ceri
- Bauer Philippe
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu
- Beegle Scott H.
- Beitler Jeremy R.
- Bellani Giacomo
- Beloncle Francois
- Benslama Abdellatif
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans Frantz
- Besset Sebastien
- Bettini Lisandro R.
- Beuret Pascal
- Bezzi Marco G.
- Bhardwaj Vallish K.
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Binti Pengiran Haji Ismail Dayangku Hajah Maizatul Aiman
- Biondi Rodrigo S.
- Biscione Roberto
- Bisso Mariano Carboni
- Black Colin
- Blakeman Thomas C.
- Blanco Javier
- Bolon Stefan
- Borello Silvina A.
- Borotto Erika
- Botteri Marco
- Bouchoucha Slaheddine
- Boukhazna Messabi
- Bouw Maria J.
- Boyd Owen
- Bramall Jon
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M.
- Briquet Anais
- Brito Vania A.
- Brizuela Matias
- Broman Lars M.
- Brown Samuel M.
- Browne Troy S.
- Bruhn Alejandro R.
- Brunettini Barbara
- Bruns Monique
- Buensuseso Juan
- Bugedo Guillermo
- Buise Marc
- Bulpa Pierre A.
- Bumbasierevic Vesna
- Bumbasirevic Vesna
- Burtenshaw Andrew
- Burtin Philippe
- Buzancais Gautier
- Béduneau Gaetan
- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
- Carbayo-Gorriz Cecilia
- Cardonnet Luis P.
- Careless Jon P.
- Carpentier Dorothée
- Carreño Nicolás G.
- Carteaux Guillaume
- Casalena Paolo
- Casement Jonathan
- Castro Alejandro
- Castro Silvia
- Catorze Nuno T.
- Cazorla-Barranquero Francisca G.
- Ceniceros-Barros Alexandra
- Cereijo Enrique
- Cerny Vladimir
- Cerrato Valeria I.
- Cervantes Mavy Ramirez
- Cesar Palazon Sanchez
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman Rhiannon
- Chau Simon
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Cheng Meisy Perez
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry Shazia
- Christiansen Aage
- Cimic Nedim
- Cinnella Gilda
- Cirone Rob
- Citalán Johanna E.
- Claraco-Vega Luis M.
- Clarkson Kevin
- Clarkson Kevin
- Claverias Laura
- Cohen Jason
- Cole Jade M.
- Collins Daniel
- Collyer Thomas
- Colombo Riccardo
- Combaux Daniele M.
- Combes Alain
- Conti Sara
- Cooper Raphael
- Coppadoro Andrea
- Corneci Dan
- Cortegiani Andrea
- Cortez Cesar
- Coxo Cristina
- Cracchiolo Andrea
- Cranshaw Julius
- Crapelli Giulia
- Crouch Daniel
- Crova Philippe
- Csabi Peter
- Curley Gerard
- Curto Elena Gallego
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric
- Daubin Cédric
- Daviaud Fabrice
- Davies Kyle G.
- Dawson Heidi
- de Cima-Iglesias Sara
- de Gordoa Laura Ortiz-Ruiz
- de Haro Candelaria
- de Pablo Raul
- de Prost Nicolas
- Dean Michael N.
- Declercq Pierre-Louis M.
- Dector Dulce
- Dector Dulce M.
- Deicas Alberto
- Dellamonica Jean
- Dellera Christian
- Delsing Angela
- Demirkiran Oktay
- Demoule Alexandre
- Dempsey Ged
- Dendane Tarek
- Depuydt P.
- Depuydt Pieter
- Derman Suleyman S.
- Di Tomasso Nora
- Di Yu
- Diaz-Rodriguez Esther
- Dive Alain M.
- Dixit Subhal
- do Vale Fernandes Antero
- Dolva Merete S.
- Donnelly Adrian
- Dowling Anna T.
- Doyen Denis
- Dres Martin
- Dreyer Kyle
- Dunne Eimhin
- Dupont Herve
- Duranteau Jacques
- Dwyer Rory
- Démpair Gabriel
- Ebeid Alejandro
- Elatrous Souheil
- Elisabet Garcia M.
- Elkhayari Mina
- Ellis Helen E.
- Elmasri Mary
- Erbabacan Emre
- Eriksson Karin
- Estenssoro Elisa
- Esteve Francisco
- Estilita Joana M.
- Estrella Claudia R.
- Ezzouine Hanane
- Fan Eddy
- Fartoukh Muriel
- Farías Pamela A.
- Fawkes Danielle A.
- Ferguson Andrew
- Ferguson Niall D.
- Fernandez Adriana M.
- Fernandez Ruben O.
- Fierro Jonathan M.
- Floris Leda
- Follin Arnaud
- Fontenele Danielle C.
- Formenti Paolo
- Forteza Catalina
- Fossali Tommaso
- Foti Giuseppe
- Franco Nieves
- Francois Guy
- França Ana
- Frati Elena
- Frendl Gyorgy
- Frigyik Aniko
- Fusari Maurizio
- Futami Satoru
- Gally Josette
- Ganesan Deeban
- Gao Yan
- Gao Yuan
- Garcia Patricio H.
- Gazenkampf Andrey A.
- Gelée Bruno
- George Fernando
- Ghazi Mohammed
- Gianinetto Hernan
- Giarratano Antonino
- Gillis Sarah
- Girgin Nermin Kelebek
- Gjedsted Jakob
- Glietsch Rita
- Goldgran-Toledano Dany
- Goligher Ewan C.
- Gomaa Dina
- Gomes Rui
- Gomez Pablo E.
- Gomez-Flores Saira S.
- Gonzalez Daniel
- Gonzalez Marcos
- González Raquel Montiel
- González-Salamanca Ángela
- Gonçalves Claudio H.
- Goodson Jennifer
- Gordo Federico
- Gosselin Ryan
- Goubaux Bernard
- Grasselli Giacomo
- Graziani Romano
- Gregoretti Cesare
- Grelon Fabien
- Griffin Ruth
- Grigoriev Evgeny
- Grijalba Carolina Quintana
- Grissom Colin K.
- Gritsan Alexey
- Grubissich Nicolas
- Gueret Renaud
- Gurjar Mohan
- Guttormsen Anne B.
- Guérin Claude
- Gómez Pilar Ricart Aroa
- Hacking Danielle J.
- Haddad Youssef
- Hadfield Dan
- Hagan Samantha J.
- Han Hui
- Han Yi
- Hang Ai
- Hanlon Gabrielle C.
- Harasawa Tomofumi
- Harrois Anatole
- Hashemian S. M.
- Hashemian Seyed Mohammadreza
- Hashida Tomoaki
- He Zhenyang
- Hedlund Lars
- Heidari Farshad
- Heines Serge
- Helleberg Johan
- Henderson Galen
- Herbrecht Jean-Etienne
- Hermosa Cecilia
- Hessell Robert
- Heunks Leo
- Higashijima Ushio
- Hirata Akira
- Holzgraefe Bernhard
- Honda Hiroyuki
- Honrubia Teresa
- Hopf Hans-Bernd F.
- Hopkins Phil
- Hormis Anil P.
- Hou Peter
- Hou Sen-Kuang
- Hraiech Sami
- Hua Ma X.
- Huang Qing
- Huang Xiao B.
- Huerta Francisco P.
- Huff Nidhi
- Humphreys Sally K.
- Hunt Anna
- Hurtado Javier
- Hutchison Robyn
- Hutton Paula J.
- Ibañez-Santacruz Marco
- Ichikado Kazuya
- Ilutovich Santiago
- Imai Hiroshi
- Imma Vallverdu
- Imperio María C.
- Insaurralde Carolina S.
- Inskip Deborah M.
- Ioannou Nicholas
- Iotti Giorgio
- Irvine Donald A.
- Ismail Dina
- Ismail Mehvish
- Ito Fumihito
- Izawa Masayo
- Jaafar Rola F.
- Jakubowska Karina
- Jamaati Hamidreza
- Jarquin-Badiola Yves D.
- Jassal Mandeep
- Javeed Areej
- Jha Rajeev
- Jiang Liangyan
- Jibaja Manuel
- Jimenez Antonio
- Jochmans Sébastien
- Jog Sameer
- Jovanovic Bojan
- Judy Claine
- Jurado Maria Teresa
- Kadaba Varsha
- Kajtor Istvan
- Kakar Vivek
- Kalaitzis Evangelos
- Kalkoff Michael
- Kamel Ghassan
- Kameyama Yoshinobu
- Kamoun Salma
- Kander Thomas
- Kannan Santhana
- Kashiwa Yozo
- Kedelv Hans
- Kennedy Barry
- Khebbeb Samy
- Kheir Fayez
- Kheir Fayez M.
- Kimura Hiroyasu
- Kiourtzieva Ellada
- Kitch Barrett T.
- Knapman Karl
- Knoll Jenny
- Knowles Serena
- Kol Mark R.
- Kong Jing
- Koyama Kansuke
- Krabler Jens
- Krstevski Amanda
- Kulkarni Shreedhar
- Kumar Alek
- Kurahashi Kiyoyasu
- Kusumoto Kohei
- Laake Jon
- Labarca Eduardo F.
- Laffey John
- Laffey John G.
- Lamb Keith
- Lanspa Michael
- Larsson Anders
- Larsson Niklas
- Lebbinck Herve
- Lee Jarone
- Leemann-Refondini Corinne
- Lemiale Virginie
- Lemus Jordana
- Leon Yoshido Hector
- Li Bin
- Li Qingdong
- Li Qiong
- Li Wenwen
- Li Xiao L.
- Li Xinyu
- Li Yimin
- Li Yuan
- Li-Xin Zhou
- Liew Kong
- Ling Long L.
- Liu Haitao
- Liu Jian
- Liu Jing
- Liu Ling
- Llano Miguel
- Llinares Moya David
- Lohner Ralph
- Loiacono Flavia A.
- Lombardo Andrea
- Lopez Esther Bermejo
- Lopez-Delgado Juan
- Lora Fredy
- Lora Pilar
- Lorente Jose A.
- Lorente Maria del Carmen
- Losada Elena Perez
- Lovazzano Pablo
- Lu Weihua
- Lu Yuanhua
- Luis Palazon Sanchez Eugenio
- Luo Xiaoming
- Lynch Joan M.
- López-Messa Juan B.
- Maazouzi Wajdi
- Macfadyen Rosaleen
- MacFie Caroline
- Madotto Fabiana
- Maeyama Hiroki
- Maghrabi Khalid
- Magret Monica
- Mahto Heera
- Mancebo Jordi
- Manoharan Venika
- Marcos Diego Pastor
- Marcu Alexandra
- Marin Julien
- Marin Maria
- Martinez Felipe T.
- Marum Susan
- Massa Eleni V.
- Mataloun Sergio
- Matamis Dimitrios
- Matsumoto Shuhei
- Mattei Alessia
- May Martin
- Mcarthur Colin
- McAuley Daniel
- McAuley Danny
- Mccalman Katie
- Mckechnie Stuart
- Mckee Raymond
- Mckenna Toni E.
- Mcleod Alex
- McNamee Lia
- Meaney Edel
- Meco Basak Ceyda
- Meersseman Philippe
- Mehta Sangeeta
- Mejia Francisco Javier Flores
- Mellis Clare
- Memon Mohammedfaruk
- Mercat Alain
- Mesar Tomaz
- Messias António M.
- Messika Jonathan
- Meybohm Patrick
- Michel Philippe
- Millar Rebecca T.
- Miller Jennene J.
- Miller Russel R.
- Mirabella Lucia
- Mizuguchi Ichiko
- Moal Charlene Le
- Mochizuki Katsunori
- Mohr Nicholas
- Mojoli Francesco
- Moles Silvia Iglesias
- Molin Alexandre
- Montanha Gustavo
- Monteiro Jorge
- Montero Laura Alvarez
- Monti Giacomo
- Montini Luca M.
- Moock Marcelo
- Morin Anna-Karin
- Mortaza Satar
- Morton Alex
- Mouloudi Eleni
- Mukkera Satyanarayana Reddy
- Mustafa Ghanem M.
- Muthuchellappan Radhakrishnan
- Máca Jan
- Nagy Eva
- Nakamura Tomoyuki
- Namih Miriam
- Nassar Antonio P.
- Nasu Michitaka
- Navalpotro Miguel Angel Blasco
- Navarra Leanlove
- Navarro Gonzalo
- Neal John
- Negoita Silvius Ioan
- Newby Lynette
- Nichol Alistair
- Nielsen Jonas
- Niimi Daisuke
- Nin Nicolás
- Nishikawa Erin
- Nitta Kenichi
- Nobrega Danielle
- Noremark Kim Andre
- Nunci Lordian
- Nunes Silvia
- Nunomiya Shin
- Nutt Christopher
- Nuñez Edgardo
- Nygren Ingela
- O'Croinin Donall
- O'Muircheartaigh Aogan C.
- Occhipinti Giovanna
- Oetting Trevor W.
- Ogino Yasuaki
- Oikonomou Marina A.
- Okane Sinead
- Okuda Nao
- Oldroyd Matthew G.
- Olga Moreno F.
- Oliveira Bruno S.
- Oneill Orla
- Ortiz Claudia A.
- Oscanoa Fredy A. Montes
- Osman Emilio M.
- Oss Peteris
- Ouanes Islem
- Ourailogloy Vasilis
- Owens Robert L.
- Ozcelik Menekse
- Palaniswamy Vijayanand
- Palma Daniela M.
- Palmese Salvatore
- Palo Jose Emmanuel
- Panarello Giovanna
- Papanikolaou Metaxia
- Papavasilopoulou Theonymfi G.
- Papazian Laurent
- Papurica Marius
- Para Luis Herrera
- Parhar Ken
- Parotto Matteo
- Pasanting-Lim Rossini Abbie
- Patroniti Nicolò
- Pattarino Pierpaolo Terragni Ilaria
- Pecci Elisabetta
- Pellegrini Carlos A.
- Pelletier Nicolas
- Pellicer Ana
- Penuelas Oscar
- Pereira Carlos
- Perez Cesar P.
- Perez Manuel
- Persson Linnea
- Pesenti Antonio
- Pham Tai
- Phan Nga T.
- Piacentini Enrique
- Pillai Suresh
- Pintado Maria
- Piquilloud Lise
- Piras Claudio
- Pittini Gustavo
- Plotnikow Gustavo A.
- Poblano Manuel
- Poli Michela M.
- Pota Vincenzo
- Pozo Norberto C.
- Pozzi Matteo
- Preez Pieter
- Prieto-González Miryam
- Pronovost Antoine
- Protti Alessandro
- Qin Bingyu
- Qin Junping
- Qin Shu H.
- Qin Tie
- Qiu Haibo
- Raaijmakers Monique
- Rabboni Francesca
- Rafael Sánchez I.
- Raimondi Ferdinando
- Raj Ashok
- Ramakrishnan Nagarajan
- Ramesh Venkatapura J.
- Ramirez-Alfaro Christian M.
- Ramirez-Gutierrez Alvaro
- Rampinelli Adenilton M.
- Ranero Jorge Luis
- Raponi Francesco
- Recio Noelia
- Reschreiter Henrik
- Reske Andreas
- Reuter Danielle
- Reynolds Claire
- Rhayakar Rachana V.
- Rialp Gemma
- Richecoeur Jack
- Ricome Sylvie
- Rigaud Jean-Philippe
- Rinia Myra
- Rios Fernando
- Riss Katharina C.
- Rittayamai Nuttapol
- Roberts Brigit L.
- Robine Adrien
- Robles Joanne B.
- Roche-Campo Ferran
- Rodgers Helen J.
- Rodriguez Lucia L.
- Rodriguez Ruben
- Rojas Manuel A. González
- Rosa Jonas I.
- Roser Tomas
- Rossi Anna
- Roux Damien
- Rugonfalvi Szabolcs
- Ruiz Silvia Rodriguez
- Ruiz-Aguilar Antonio
- Rylander Christian C.
- Ryosuke Sekine
- Sabelnikovs Olegs
- Sable Safal D.
- Saenz María G.
- Saez Alejandro A.
- Sagar Sudha V.
- Saito Koji
- Saito Shigeki
- Salahuddin Nawal
- Salas Javier E.
- Sales Brunei Vanessa M.
- Samkaoui Nacer
- Sanchez Roberto Jimenez
- Sanchez-Hurtado Luis
- Sanchez-Medina Jorge
- Sandesc Dorel
- Santoli Francesco L.
- Santos Cristina
- Sauvadet Elise
- Savioli Monica
- Scafetti Sergio
- Schiavone Vincenzo
- Schiavoni Lorenzo
- Schiöler Fredrik
- Schlichting Adam
- Schneider Francis
- Schomer Ashley
- Schouten Jeroen A.
- Schuetz Michael
- Schultz Marcus J.
- Schäfer Susanne
- Scott Christopher
- Seasman Colette
- Seethala Raghu
- Sellors Gareth P.
- Seoane-Quiroga Leticia
- Serra Aurelia Isabel
- Serra Carolina
- Setten Mariano G.
- Seven Aylin
- Shah Bhagyesh
- Shao Huanzhang
- Shen Juanhong
- Shenoy Anitha
- Sher Sara
- Shimizu Kazuyoshi
- Shindhe Suresh
- Shinn Iii John O.
- Shiozaki Kyoko
- Silesky Jimenez Juan
- Silesky Juan
- Sim Malcolm
- Simon Philipp
- Simonis Fabienne
- Sivashanmugavel Mageswaran
- Sjøbø Brit A.
- Sklienka Peter
- Smith Mark
- Smith Oliver
- Soler Juan Alfonso
- Solis-Quesada Jaime E.
- Sotillo Diaz Juan Carlos
- Sottiaux T.
- Souissi Asma Ben
- Spadaro Savino
- Srinivasa Latha
- Stamou Electra E.
- Staudinger Thomas
- Stephenson Lorraine
- Stewart Richard
- Stigler William
- Strauch Ulrich
- Sula Hektor
- Sun Renhua
- Surbatovic Maja
- Suzuki Hiroyuki
- Symmonds Sophie
- Szakmany Tamas
- Sánchez Rocío Manzano
- Sánchez-Ballesteros Jesús
- Søreide Eldar
- Tabhan Edgardo
- Tabhan Edgardo E.
- Tainter Christopher
- Takaba Akihiro
- Takada Tadaaki
- Takagi Shunsuke
- Tan Beatriz C.
- Tanaka Hiroyuki
- Tang Rui
- Tapponnier Romain
- Tarantino Fabio
- Temprano Susana
- Terzi Nicolas
- Thibault Sandrine
- Thomas Matthew
- Thompson Marlus M.
- Tibblin Anna Oscarsson
- Tinnirello Andrea
- Tiribelli Norberto
- Todeschini Manuel
- Tomescu Dana
- Toribio Dácil Parrilla
- Toth-Tarsoly Piroska
- Treanor Nuala
- Trinder T. John
- Trinidad Olivia A.
- Tulaimat Aiman
- Twohey Linda
- Uchiyama Akinori
- Ueda Takeshi
- Ueno Keiko
- Umbrello Michele
- Unnikrishnan Ramesh
- Uppalapati Aditya
- Van Haren Frank
- Van Wezel Hellen M.
- Vargas Monica
- Vascotto Ettore
- Vasquez Daniela N.
- Vega Luis D.
- Veljovic Milic
- Venti Aaron
- Vercueil Andre
- Vermassen Joris
- Verstraete Rik
- Villagomez Asisclo
- Villagomez Asisclo J.
- Villamagua Boris
- Villar Veronica
- Vinzio Mauricio
- Virgilio Corcoles G.
- Vitale Michela N.
- Volta Carlo A.
- Wang Chunting
- Wang Hua
- Wang Shou H.
- Wang Wei
- Warren Jessica
- Watanabe Eizo
- Watt Philip
- Welters Ingeborg
- Wenham Tim
- Wessbergh Joanna
- Whitehead Christina
- Willett Emma L.
- Williams Alexandra J.
- Williams Karen E.
- Wise Matt
- Wittebole Xavier
- Wong Helen S.
- Woods Paul W.
- Wrathall David
- Wrigge Hermann
- Wu Ya
- Xin-Hua Qiang
- Xu Yonghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L.
- Yeatts Dale
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste Luis J.
- Zacharas Giannis
- Zacharowski Kai
- Zani Gianluca
- Zantua Kim
- Zazu Alan
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao Huiying
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa C.
- Zhou Suming
- Zhu Bao
- Zhu Wei H.
- Zogheib Elie
- Ñamendys-Silva Silvio A.
- ünal Necmettin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiogenic shock were their most common risk factors for ARDS. Hospital mortality was higher in immunocompromised than in immunocompetent patients (52.4% vs 36.2%; p < 0.0001), despite similar severity of ARDS. Decisions regarding limiting life-sustaining measures were significantly more frequent in immunocompromised patients (27.1% vs 18.6%; p < 0.0001). Use of noninvasive ventilation (NIV) as first-line treatment was higher in immunocompromised patients (20.9% vs 15.9%; p = 0.0048), and immunodeficiency remained independently associated with the use of NIV after adjustment for confounders. Forty-eight percent of the patients treated with NIV were intubated, and their mortality was not different from that of the patients invasively ventilated ab initio. Conclusions: Immunosuppression is frequent in patients with ARDS, and infections are the main risk factors for ARDS in these immunocompromised patients. Their management differs from that of immunocompetent patients, particularly the greater use of NIV as first-line ventilation strategy. Compared with immunocompetent subjects, they have higher mortality regardless of ARDS severity as well as a higher frequency of limitation of life-sustaining measures. Nonetheless, nearly half of these patients survive to hospital discharge. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013
Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study
- Author
- Aage Christiansen
- Aaron Venti
- Abdellatif Benslama
- Adam B Schlichting
- Adenilton M Rampinelli
- Aditya Uppalapati
- Adrian Donnelly
- Adriana M Fernandez
- Adrien Robine
- Ahmad Yazid Bin Hj Abul Wahab
- Ahmed S Al Jabbary
- Ai Y Hang
- Aiman Tulaimat
- Akihiro Takaba
- Akinori Uchiyama
- Akira Hirata
- Alain Combes
- Alain M Dive
- Alain Mercat
- Alain U Alisasis
- Alan Zazu
- Alberto Deicas
- Alec A Tallet Alfonso
- Alejandro A Saez
- Alejandro Ebeid
- Alejandro G Castro
- Alejandro R Bruhn
- Alejandro Rojas
- Alek Kumar
- Alessandro Protti
- Alessia Mattei
- Alex Mcleod
- Alex Morton
- Alexandra Ceniceros-Barros
- Alexandra J Williams
- Alexandra Marcu
- Alexandre Demoule
- Alexandre Molin
- Alexey I Gritsan
- Alfons Arizmendi
- Aline Ascoli
- Alistair Nichol
- Alma Cani
- Alvaro Ramirez-Gutierrez
- Amanda Krstevski
- Amine Ali Zeggwagh
- Amine Ali Zeggwagh
- Ana Carolina P Antônio
- Ana G França
- Ana M Araujo
- Ana M Pellicer
- Anais Briquet
- Anatole Harrois
- Anders Aneman
- Anders Larsson
- Anders Larsson
- Andre Vercueil
- Andrea Coppadoro
- Andrea Cortegiani
- Andrea Lombardo
- Andrea N Cracchiolo
- Andrea Tinnirello
- Andreas Barratt-Due
- Andreas W Reske
- Andres Esteban
- Andrew Ferguson
- Andrew J Burtenshaw
- Andrey A Gazenkampf
- Angela Delsing
- Aniko D Frigyik
- Anil P Hormis
- Anitha Shenoy
- Anna Hunt
- Anna Oscarsson Tibblin
- Anna T Dowling
- Anna-Karin Morin
- Anne Adolfsson
- Anne B Guttormsen
- Antero do Vale Fernandes
- Antoine Pronovost
- Antonino Giarratano
- Antonio Artigas
- Antonio Braschi
- Antonio G Jimenez
- Antonio L RuizAguilar
- Antonio P Nassar Jr
- Antonio Pesenti
- António M Alvarez
- António M Messias
- Aogan C O'Muircheartaigh
- Areej Javeed
- Ariel Chena
- Arnaud Follin
- Arthur S Slutsky
- Arvind K Baronia
- Ashley Schomer
- Ashok S Raj
- Asisclo J Villagomez
- Asisclo Villagomez
- Asma Ben Souissi
- Aurelia M Martinho
- Aylin Seven
- B Taylor Thompson
- Bao H Zhu
- Barbara Brunettini
- Barrett T Kitch
- Barry Kennedy
- Basak Ceyda Meco
- Beatriz C Tan
- Bellani Giacomo
- Bernard Goubaux
- Bernhard Holzgraefe
- Bhagyesh Shah
- Bin Li
- Bingyu Qin
- Bojan Jovanovic
- Boris G Villamagua
- Brigit L Roberts
- Brit Å Sjøbø
- Brochard Laurent J.
- Bruhn Alejandro
- Bruno Gelée
- Bruno S Oliveira
- Bugedo Guillermo
- Candelaria De Haro
- Carlo A Volta
- Carlos A Pellegrini
- Carlos S Pereira
- Carolina Quintana Grijalba
- Carolina S Insaurralde
- Carolina Serra
- Caroline Berghe
- Caroline C MacFie
- Catalina Forteza
- Cecilia Carbayo-Gorriz
- Cecilia Hermosa
- Ceri E Battle
- Cesar A Cortez
- Cesar P Perez
- Charlene Bigot
- Charlene Le Moal
- Christian C Rylander
- Christian Dellera
- Christian M Ramirez-Alfaro
- Christina Whitehead
- Christopher J Scott
- Christopher Nutt
- Christopher Tainter
- Chunting Wang
- Claine Judy
- Claire Reynolds
- Clare Mellis
- Claude Guérin
- Claudia A Ortiz
- Claudia R Estrella
- Claudio H Gonçalves
- Claudio Piras
- Colette Seasman
- Colin K Grissom
- Colin McArthur
- Colin S Black
- Corcoles G Virgilio
- Corinne Leemann-Refondini
- Cristina M Coxo
- Cristina Santos
- Cédric Daubin
- Daisuke Niimi
- Dale J Yeatts
- Damien Roux
- Dan E Corneci
- Dan Hadfield
- Dana R Tomescu
- Daniel F McAuley
- Daniel F McAuley
- Daniel O Beraldo
- Daniel R Crouch
- Daniel R Crouch
- Daniel R Gonzalez
- Daniel V Collins
- Daniela Albiero
- Daniela M Palma
- Daniela N Vasquez
- Daniele M Combaux
- Danielle A Fawkes
- Danielle C Fontenele
- Danielle J Hacking
- Danielle Nobrega
- Danielle Reuter
- Danny McAuley
- Dany Goldgran-Toledano
- David D Llinares Moya
- David W Wrathall
- Deborah M Inskip
- Deeban Ganesan
- Denis Doyen
- Diego Pastor Marcos
- Dimitrios Matamis
- Dina Gomaa
- Dina Gomaa
- Dina Ismail
- Donald A Irvine
- Donall O'Croinin
- Dorel Sandesc
- Dorothy M Breen
- Dorothée Carpentier
- Dulce Dector
- Dácil Parrilla Toribio
- Ed Bajwa
- Eddy Fan
- Eddy Fan
- Edel A Meaney
- Edgardo E Tabhan
- Edgardo Nuñez
- Edgardo Tabhan
- Eduardo Beck
- Eduardo F Labarca
- Eimhin S Dunne
- Eizo Watanabe
- Eldar Søreide
- Electra E Stamou
- Elena Frati
- Elena Gallego Curto
- Elena Perez Losada
- Eleni K Mouloudi
- Eleni V Massa
- Elie H Zogheib
- Elisa Estenssoro
- Elisabetta Pecci
- Elise P Sauvadet
- Ellada V Kiourtzieva
- Emilio M Osman
- Emma L Willett
- Emre Erbabacan
- Enrique A Piacentini
- Enrique Cereijo
- Erika E Borotto
- Erin Nishikawa
- Esteban Andres
- Esther Bermejo Lopez
- Esther Diaz-Rodriguez
- Ettore R Vascotto
- Eva O Nagy
- Evangelos Kalaitzis
- Evgeny Grigoriev
- Ewan C Goligher
- Fa C Zhou
- Fabien Grelon
- Fabienne D Simonis
- Fabio Tarantino
- Fabrice Daviaud
- Fahd Amir
- Fan Zhang
- Fan Eddy
- Farshad Heidari
- Fayez Kheir
- Fayez M Kheir
- Federico Gordo
- Fekri Abroug
- Felipe A Aliaga
- Felipe T Martinez
- Ferdinando Raimondi
- Fernandes Antero do Vale
- Fernando G George
- Fernando Rios
- Ferran RocheCampo
- Filipa M Barros
- Finn H Andersen
- Flavia A Loiacono
- Francesco L Santoli
- Francesco Mojoli
- Francesco Raponi
- Francis Schneider
- Francisca G Cazorla-Barranquero
- Francisco Esteve
- Francisco Javier Flores Mejia
- Francisco P Huerta
- Francois Beloncle
- Frank van Haren
- Frank van Haren
- Frantz Berkelmans
- Fredrik Schiöler
- Fredy A Montes Oscanoa
- Fredy S Lora
- Fumihito Ito
- Gabriel Démpaire
- Gabrielle C Hanlon
- Gaetan Béduneau
- Galen Henderson
- Garcia M Elisabet
- Gareth P Sellors
- Gattinoni Luciano
- Gautier Buzancais
- Ged Dempsey
- Gemma Rialp
- Gerard Curley
- Ghaleb Almekhlafi
- Ghanem M Mustafa
- Ghassan Kamel
- Giacomo Bellani
- Giacomo Bellani
- Giacomo Monti
- Gianluca Zani
- Giannis A Zacharas
- Gilda Cinnella
- Giorgio A Iotti
- Giovanna Occhipinti
- Giovanna Panarello
- Giulia Crapelli
- Giuseppe Foti
- Gonzalo Navarro
- Gordon Rubenfeld
- Guillaume Barberet
- Guillaume Carteaux
- Guillermo Bugedo
- Guillermo M Albaiceta
- Gustavo A Plotnikow
- Gustavo M Montanha
- Gustavo Pittini
- Gyorgy Frendl
- Haibo Qiu
- Haibo Qiu
- Haitao Liu
- Hamidreza Jamaati
- Hanane Ezzouine
- Hans Kedelv
- HansBernd F Hopf
- Hasan M Al Dorzi
- Hector H Leon Yoshido
- Heera L Mahto
- Heidi Dawson
- Hektor Sula
- Helen E Ellis
- Helen J Rodgers
- Helen S Wong
- Helga Ceunen
- Hellen M van Wezel
- Henrik Appelberg
- Henrik Reschreiter
- Hermann Wrigge
- Hermann Wrigge
- Hernan Aguirre-Bermeo
- Hernan Gianinetto
- Herve Dupont
- Herve Lebbinck
- Hervé O Zender
- Hicham Balkhi
- Hiroki N Maeyama
- Hiroshi Imai
- Hiroyasu Kimura
- Hiroyuki Honda
- Hiroyuki Suzuki
- Hiroyuki Tanaka
- Hitesh Batra
- Hua X Wang
- Huanzhang Shao
- Hui Han
- Huiying Zhao
- Ichiko Mizuguchi
- Iguel Llano
- Ilaria Pattarino
- Ilkay Ceylan
- Imed Chouchene
- Imo Aisiku
- Ingeborg D Welters
- Ingela Nygren
- Irene M Bailey
- Isabel M Serra
- Islem Ouanes
- Istvan Kajtor
- Jack R Richecoeur
- Jacob S Yumha
- Jacques Duranteau
- Jade M Cole
- Jaime E SolisQuesada
- Jakob Gjedsted
- Jan Máca
- Janet S Aguirre
- Jarone Lee
- Jason E Cohen
- Javier Alvarez
- Javier Blanco
- Javier E Salas
- Javier G Alonso
- Javier Hurtado
- Javier Hurtado
- Javier Hurtado
- Jean Dellamonica
- Jean-Daniel Chiche
- Jean-Etienne Herbrecht
- Jean-Michel Arnal
- Jean-Philippe Rigaud
- Jennene J Miller
- Jennifer C Goodson
- Jenny Knoll
- Jens Kraßler
- Jeremy R Beitler
- Jeroen A Schouten
- Jerome Biehler
- Jessica Warren
- Jesús Sánchez-Ballesteros
- Jian Liu
- Jing Kong
- Jing L Liu
- Joan M Lynch
- Joana M Estilita
- Joanna Wessbergh
- Joanne B Robles
- Johan Helleberg
- Johanna E Citalán
- John C Adams
- John G Laffey
- John G Laffey
- John Laffey
- John Neal
- John O Shinn Iii
- Jon Bramall
- Jon H Laake
- Jon Henrik Laake
- Jon P Careless
- Jonas I Rosa
- Jonas Nielsen
- Jonas Nielsen
- Jonathan Casement
- Jonathan Chelly
- Jonathan M Fierro
- Jonathan Messika
- Jordana S Lemus
- Jordi Mancebo
- Jorge Luis Ranero
- Jorge M Monteiro
- Jorge R Sanchez-Medina
- Joris Vermassen
- Jose A Lorente
- Jose Emmanuel Palo
- Josette Gally
- Juan A Buensuseso
- Juan A Buensuseso
- Juan Alfonso Soler
- Juan B López-Messa
- Juan C Lopez-Delgado
- Juan Carlos J Sotillo Diaz
- Juan I Silesky Jimenez
- Juan Silesky
- Juanhong Shen
- Julie Camsooksai
- Julien Marin
- Julio C Badie
- Julio Daldin
- Julius H Cranshaw
- Jun Zhao
- Junping Qin
- Kai Chen
- Kai D Zacharowski
- Kansuke Koyama
- Karen E Williams
- Karin E Eriksson
- Karina Jakubowska
- Karl M Knapman
- Katharina C Riss
- Katie H McCalman
- Katsunori Mochizuki
- Kaushik Bhowmick
- Kazuya Ichikado
- Kazuyoshi Shimizu
- Keiko Ueno
- Keith D Lamb
- Ken Parhar
- Kenichi Nitta
- Kevin Clarkson
- Kevin P Clarkson
- Khalid A Maghrabi
- Kim Andre L Noremark
- Kim S Zantua
- Kiyoyasu Kurahashi
- Kohei Kusumoto
- Kohkichi Andoh
- Koji Saito
- Kong Y Liew
- Kyle G Davies
- Kyle R Dreyer
- Kyoko Shiozaki
- Laffey John G
- Lars Hedlund
- Lars M Broman
- Larsson Anders
- Latha Srinivasa
- Laura Alvarez Montero
- Laura Claverias
- Laura Ortiz-Ruiz de Gordoa
- Laurence Dangers
- Laurent Brochard
- Laurent Papazian
- Leanlove Navarra
- Leda Floris
- Leo M Heunks
- Leo M Heunks
- Leticia Seoane-Quiroga
- Lia McNamee
- Lia McNamee
- Liangyan Jiang
- Linda Twohey
- Ling Liu
- Linnea Persson
- Lisandro R Bettini
- Lise Piquilloud
- Lise Piquilloud
- Long L Ling
- Lordian Nunci
- Loredana Baboi
- Lorente José Angel
- Lorenzo Schiavoni
- Lorraine Stephenson
- Luca Brazzi
- Luca M Montini
- Lucia L Rodriguez
- Lucia Mirabella
- Luciano Cesar Azevedo
- Luciano Gattinoni
- Luis A Sanchez-Hurtado
- Luis D Vega
- Luis E Avila
- Luis Herrera Para
- Luis J Yuste
- Luis M Claraco-Vega
- Luis P Cardonnet
- Lynette Newby
- Ma X Hua
- Mageswaran Sivashanmugavel
- Maizatul Ismail
- Malcolm Sim
- Mandeep Jassal
- Manuel A González Rojas
- Manuel Jibaja
- Manuel P Perez
- Manuel Poblano
- Manuel Poblano
- Manuel Todeschini
- Marc P Buise
- Marcelo Moock
- Marco Botteri
- Marco G Bezzi
- Marco Ranieri
- Marcos Gonzalez
- Marcos Ibañez-Santacruz
- Marcus J Schultz
- Maria C Marin
- Maria C Pintado
- Maria Del Carmen Lorente
- Maria J Bouw
- Maria Jose D Artiga
- Mariano Carboni Bisso
- Mariano G Setten
- Marina A Oikonomou
- Marius Papurica
- Mark J Smith
- Mark R Kol
- Marlus M Thompson
- Martin Dres
- Martin M May
- Mary Elmasri
- María C Imperio
- María G Saenz
- Masayo Izawa
- Massimo M Antonelli
- Mathew B Bailey
- Matias Brizuela
- Matteo Parotto
- Matteo Pozzi
- Matthew G Oldroyd
- Matthew Thomas
- Mauricio Vinzio
- Maurizio Fusari
- Mavy Ramirez Cervantes
- McAuley Daniel F.
- Mehvish Ismail
- Meisy Perez Cheng
- Menekse Ozcelik
- Merete S Dolva
- Messabi Boukhazna
- Metaxia N Papanikolaou
- Michael J Lanspa
- Michael Kalkoff
- Michael N Dean
- Michael Schuetz
- Michela M Poli
- Michela N Vitale
- Michele Umbrello
- Michitaka Nasu
- Miguel Angel Blasco Navalpotro
- Mina Elkhayari
- Miriam Namih
- Miryam PrietoGonzález
- Mohamad M Albarrak
- Mohammed Ghazi
- Mohammedfaruk Memon
- Mohan Gurjar
- Monica Magret
- Monica P Vargas
- Monica Savioli
- Monique M Bruns
- Monique Raaijmakers
- Moreno F Olga
- Mourad Amor
- Muriel Fartoukh
- Mustafa Aker
- Myra Rinia
- Mª Teresa Jurado
- Nacer Samkaoui
- Nagarajan Ramakrishnan
- Nao Okuda
- Nawal Salahuddin
- Necmettin Ünal
- Nedim Cimic
- Nelson C Barros
- Nermin Kelebek Girgin
- Nga T Phan
- Niall D Ferguson
- Nicholas Ioannou
- Nicholas M Mohr
- Nicolas de Prost
- Nicolas Grubissich
- Nicolas Nin
- Nicolas Pelletier
- Nicolas Terzi
- Nicolás G Carreño
- Nicolás Nin
- Nicolò Patroniti
- Nidhi G Huff
- Nieves Franco
- Niklas Larsson
- Nobumasa Aoki
- Noelia N Recio
- Nora N Di Tomasso
- Norberto C Pozo
- Norberto Tiribelli
- Nuala Treanor
- Nuno T Catorze
- Nuttapol Rittayamai
- Oktay Demirkiran
- Olaitan O Ajetunmobi
- Olegs Sabelnikovs
- Oliver Beck
- Oliver Smith
- Olivia A Trinidad
- Onat O Akyol
- Orla Oneill
- Osamu Yamaguchi
- Oscar Penuelas
- Ovidiu H Bedreag
- Owen Boyd
- Pablo E Gomez
- Pablo Lovazzano
- Palazon Sanchez Cesar
- Palazon Sanchez Eugenio Luis
- Pamela A Farías
- Paolo Casalena
- Paolo Formenti
- Pascal Beuret
- Patricio H Garcia
- Patrick Meybohm
- Paul W Woods
- Paula J Hutton
- Pawel Andruszkiewicz
- Pesenti Antonio
- Peter Alexander
- Peter C Hou
- Peter Csabi
- Peter Sklienka
- Peteris Oss
- Pham Tài
- Phil Hopkins
- Philip Watt
- Philipp Simon
- Philippe Burtin
- Philippe J Crova
- Philippe Meersseman
- Philippe Michel
- Philippe R Bauer
- Pierpaolo Terragni
- Pierre A Bulpa
- Pierre-Eric Danin
- PierreLouis M Declercq
- Pieter D Preez
- Pieter Depuydt
- Pieter Depuydt
- Pilar Lora
- Pilar Ricart Aroa Gómez
- Piroska Toth-Tarsoly
- Pravin Amin
- Qiang Xin-Hua
- Qing Q Huang
- Qingchun Yao
- Qingdong Li
- Qiong J Li
- Rachana V Rhayakar
- Radhakrishnan Muthuchellappan
- Raghu Seethala
- Rajeev R Jha
- Ralph Lohner
- Raman Azad
- Ramesh Unnikrishnan
- Ranieri Marco
- Raphael Cooper
- Raquel Montiel González
- Raquel Montoiro Allue
- Raul De Pablo
- Raymond Mckee
- Rebecca M Baro
- Rebecca T Millar
- Renaud M Gueret
- Renhua Sun
- Rhiannon Chapman
- Ricardo Diaz Abad
- Riccardo Colombo
- Richard Stewart
- Rik Verstraete
- Rios Fernando
- Risso V Alejandro
- Rita Glietsch
- Rob Cirone
- Robert J Hessell
- Robert L Owens
- Roberto Jimenez Sanchez
- Roberto R Biscione
- Robyn A Hutchison
- Rocío Manzano Sánchez
- Rodrigo S Biondi
- Rola F Jaafar
- Romain Tapponnier
- Romano Graziani
- Ronald Zumaran Aguilar
- Rongguo Yu
- Rory Dwyer
- Rosa S Alda
- Rosaleen Macfadyen
- Rossini Abbie B Pasanting-Lim
- Ruben O Fernandez
- Ruben Rodriguez
- Rubenfeld Gordon
- Rui M Gomes
- Rui Tang
- Ruiqiang Zheng
- Russel R Miller
- Russell Chabanne
- Russell M Allan
- Ruth O Griffin
- Ryan J Gosselin
- S M Hashemian
- Safal D Sable
- Saira S Gomez-Flores
- Salem Ould Zein
- Sally K Humphreys
- Salma Kamoun
- Salvatore Palmese
- Samantha J Hagan
- Sameer A Jog
- Sami Hraiech
- Samuel M Brown
- Samy Khebbeb
- Sandrine Thibault
- Sangeeta Mehta
- Santhana G Kannan
- Santiago Ilutovich
- Sara De Cima-Iglesias
- Sarah Gillis
- Satar Mortaza
- Satoru Futami
- Satyanarayana Reddy Mukkera
- Savino Spadaro
- Scott H Beegle
- Sebastien L Besset
- Sekine Ryosuke
- Sen-Kuang Hou
- Serena Knowles
- Serge J Heines
- Sergio Canestrini
- Sergio Mataloun
- Sergio Scafetti
- Seyed Mohammadreza Hashemian
- Shailesh Bihari
- Shazia Choudry
- Shigeki Saito
- Shin Nunomiya
- Shou H Wang
- Shreedhar Kulkarni
- Shu H Qin
- Shuhei Matsumoto
- Shunsuke Takagi
- Silvia Castro
- Silvia Iglesias Moles
- Silvia L Nunes
- Silvia Rodriguez Ruiz
- Silvina A Borello
- Silvio A Ñamendys-Silva
- Silvius Ioan Negoita
- Simon K Chau
- Sinead C Okane
- Siu-Ming Au
- Slaheddine Bouchoucha
- Sophie Symmonds
- Souheil Elatrous
- Stefan Bolon
- Stuart Mckechnie
- Subhal B Dixit
- Sudha V Sagar
- Suleyman S Derman
- Suming Zhou
- Suresh Pillai
- Suresh Shindhe
- Susan M Marum
- Susana TempranoSusana
- Susanne Schäfer
- Sylvie Ricome
- Szabolcs Rugonfalvi
- Sánchez I Rafael
- Sébastien Jochmans
- T John Trinder
- Tadaaki Takada
- Takeshi Ueda
- Tamas Szakmany
- Tao Yu
- Tarek Dendane
- Teresa Honrubia
- Tharwat M Aisa
- Theonymfi G Papavasilopoulou
- Thierry Sottiaux
- Thomas Baltus
- Thomas C Blakeman
- Thomas Collyer
- Thomas Kander
- Thomas Staudinger
- Thompson B. Taylor
- Tie H Qin
- Tim Wenham
- Tomas P Roser
- Tomaz MesarJarone Lee
- Tommaso Fossali
- Tomoaki Hashida
- Tomofumi Harasawa
- Tomoyuki Nakamura
- Toni E McKenna
- Toshikazu Abe
- Trevor W Oetting
- Troy S Browne
- Tài Pham
- Tài Pham
- Tài Pham
- Ulrich Strauch
- Ushio Higashijima
- Valeria I Cerrato
- Valerie M Banner-Goodspeed
- Vallish K Bhardwaj
- Vallverdu P Imma
- Van Haren Frank
- Vanessa M Sales
- Vania A Brito
- Varsha Kadaba
- Vasilis Ourailogloy
- Venika Manoharan
- Venkatapura J Ramesh
- Veronica Villar
- Vesna Bumbasierevic
- Vesna Bumbasirevic
- Vijayanand Palaniswamy
- Vincenzo Pota
- Vincenzo Schiavone
- Virginie Lemiale
- Vivek Kakar
- Vladimir Cerny
- Wahid Altaf
- Wajdi Maazouzi
- Wei H Zhu
- Wei Wang
- Weihua Lu
- Wenkui Yu
- Wenwen Li
- William Stigler
- Wrigge Hermann
- Xavier Wittebole
- Xian Y Zhao
- Xiao B Huang
- Xiao L Li
- Xiaoming Luo
- Xing Y Zhang
- Xinyu Li
- Ya Q Wu
- Yaasen Arabi
- Yan Gao
- Yaseen M Arabi
- Yaseen M Arabi
- Yasuaki Ogino
- Yi Han
- Yimin Li
- Yonghao Xu
- Yoshihiro Yamaji
- Yoshinobu Kameyama
- Youssef Haddad
- Youzhong An
- Yozo Kashiwa
- Yu D Di
- Yuan N Gao
- Yuan Y Li
- Yuanhua Lu
- Yves D Jarquin-Badiola
- Zhe Zhai
- Zheng L Ye
- Zhenyang He
- Zhou Li-Xin
- Ángela Algaba
- Ángela González-Salamanca
- Publication venue
- 'European Respiratory Society (ERS)'
- Publication date
- 01/01/2021
- Field of study
Background: Current incidence and outcome of patients with acute hypoxaemic respiratory failure requiring mechanical ventilation in the intensive care unit (ICU) are unknown, especially for patients not meeting criteria for acute respiratory distress syndrome (ARDS).
Methods: An international, multicentre, prospective cohort study of patients presenting with hypoxaemia early in the course of mechanical ventilation, conducted during four consecutive weeks in the winter of 2014 in 459 ICUs from 50 countries (LUNG SAFE). Patients were enrolled with arterial oxygen tension/inspiratory oxygen fraction ratio ≤300 mmHg, new pulmonary infiltrates and need for mechanical ventilation with a positive end-expiratory pressure of ≥5 cmH2O. ICU prevalence, causes of hypoxaemia, hospital survival and factors associated with hospital mortality were measured. Patients with unilateral versus bilateral opacities were compared.
Findings: 12 906 critically ill patients received mechanical ventilation and 34.9% with hypoxaemia and new infiltrates were enrolled, separated into ARDS (69.0%), unilateral infiltrate (22.7%) and congestive heart failure (CHF; 8.2%). The global hospital mortality was 38.6%. CHF patients had a mortality comparable to ARDS (44.1% versus 40.4%). Patients with unilateral-infiltrate had lower unadjusted mortality, but similar adjusted mortality compared to those with ARDS. The number of quadrants on chest imaging was associated with an increased risk of death. There was no difference in mortality comparing patients with unilateral-infiltrate and ARDS with only two quadrants involved.
Interpretation: More than one-third of patients receiving mechanical ventilation have hypoxaemia and new infiltrates with a hospital mortality of 38.6%. Survival is dependent on the degree of pulmonary involvement whether or not ARDS criteria are reached
Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis
- Author
- 1amendys-Silva Silvio A
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C
- Adamsson Richard O
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S
- Aguirre-Bermeo Hernan
- Aisa Tharwat M
- Aisiku Imo
- Ajetunmobi Olaitan O
- Aker Mustafa
- Akyol Onat O
- Al Dorzi Hasan M
- Al Jabbary Ahmed S
- Albaiceta Guillermo M
- Albarrak Mohamad M
- Albiero Daniela
- Alda Rosa S
- Alejandro Risso V
- Alexander Peter
- Alfonso Alec A Tallet
- Algaba \uc1ngela
- Aliaga Felipe A
- Alisasis Alain U
- Allan Russell M
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier G
- Altaf Wahid
- Alvarez Ant\uf3nio M
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Mourad
- Ampinelli Adenilton M R
- An Youzhong
- Andersen Finn H
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Ant\uf4nio Ana Carolina P
- Antonelli Massimo M
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M
- Araujo Ana M
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E
- Azad Raman
- Azevedo Luciano C
- B\ue9duneau Gaetan
- Baboi Loredana
- Badie Julio C
- Bailey Irene M
- Bailey Mathew B
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie M
- Barberet Guillaume
- Baron Rebecca M
- Baronia Arvind K
- Barratt-Due Andreas
- Barros Filipa M
- Barros Nelson C
- Batra Hitesh
- Battle Ceri E
- Bauer Philippe R
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu H
- Beegle Scott H
- Beitler Jeremy R
- Bellani Giacomo
- Bellani Giacomo
- Beloncle Francois
- Ben Souissi Asma
- Benslama Abdellatif
- Beraldo Daniel O
- Berghe Caroline
- Berkelmans Frantz
- Besset Sebastien L
- Bettini Lisandro R
- Beuret Pascal
- Bezzi Marco G
- Bhardwaj Vallish K
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Biondi Rodrigo S
- Biscione Roberto R
- Bisso Mariano Carboni
- Black Colin S
- Blakeman Thomas C
- Blanco Javier
- Blasco Navalpotro Miguel Angel
- Bolon Stefan
- Borello Silvina A
- Borotto Erika E
- Botteri Marco
- Bouchoucha Slaheddine
- Boukhazna Messabi
- Bouw Maria J
- Boyd Owen
- Bramall Jon
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M
- Briquet Anais
- Brito Vania A
- Brizuela Matias
- Broman Lars M
- Brown Christine
- Brown Samuel M
- Bruhn Alejandro R
- Brunettini Barbara
- Bruns Monique M
- Buensuseso Juan A
- Bugedo Guillermo
- Buise Marc P
- Bulpa Pierre A
- Bumbasierevic Vesna
- Bumbasirevic Vesna
- Burtenshaw Andrew J
- Burtin Philippe
- Buzancais Gautier
- Calfee Carolyn S
- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
- Carbayo-Gorriz Cecilia
- Cardonnet Luis P
- Careless Jon P
- Carpentier Doroth\ue9e
- Carre\uf1o Nicol\ue1s G
- Carteaux Guillaume
- Casalena Paolo
- Casement Jonathan
- Castro Alejandro G
- Castro Silvia
- Catorze Nuno T
- Cazorla-Barranquero Francisca G
- Ceniceros-Barros Alexandra
- Cereijo Enrique
- Cerny Vladimir
- Cerrato Valeria I
- Cervantes Mavy Ramirez
- Cesar Palazon Sanchez
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman Rhiannon
- Chau Simon K
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry Shazia
- Christiansen Aage
- Churpek Matthew
- Cimic Nedim
- Cinnella Gilda
- Cirone Rob
- Cital\ue1n Johanna E
- Claraco-Vega Luis M
- Clarkson Kevin
- Clarkson Kevin P
- Claverias Laura
- cnal Necmettin
- Cohen Jason E
- Cole Jade M
- Collins Daniel V
- Collyer Thomas
- Colombo Riccardo
- Combaux Daniele M
- Combes Alain
- Cooper Raphael
- Coppadoro Andrea
- Corneci Dan E
- Cortegiani Andrea
- Cortez Cesar A
- Cowley R Adams
- Cox Cristina M
- Cracchiolo Andrea N
- Cranshaw Julius H
- Crapelli Giulia
- Crouch Daniel R
- Crova Philippe J
- Csabi Peter
- Curley Gerard
- Curto Elena Gallego
- D\ue9mpaire Gabriel
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric
- Daubin C\ue9dric
- Daviaud Fabrice
- Davies Kyle G
- Dawson Heidi
- De Cima-Iglesias Sara
- De Gordoa Laura Ortiz-Ruiz
- De Haro Candelaria
- De Pablo Raul
- de Prost Nicolas
- Dean Michael N
- Declercq Pierre-Louis M
- Dector Dulce M
- Deicas Alberto
- Dellamonica Jean
- Dellera Christian
- Delsing Angela
- Delucchi Kevin L
- Demirkiran Oktay
- Demoule Alexandre
- Dempsey Ged
- Dendane Tarek
- Depuydt P
- Depuydt Pieter
- Derman Suleyman S
- Di Tomasso Nora N
- Di Yu D
- Diaz Juan Carlos J Sotillo
- Diaz-Rodriguez Esther
- Dive Alain M
- Dixit Subhal B
- do Vale Fernandes Antero
- Dolva Merete S
- Donnelly Adrian
- Dowling Anna T
- Doyen Denis
- Dres Martin
- Dreyer Kyle R
- Dunne Eimhin S
- Dupont Herve
- Duranteau Jacques
- Dwyer Rory
- Ebeid Alejandro
- Elatrous Souheil
- Elisabet Garcia M
- Elkhayari Mina
- Ellis Helen E
- Elmasri Mary
- Erbabacan Emre
- Eriksson Karin E
- Estenssoro Elisa
- Esteve Francisco
- Estilita Joana M
- Estrella Claudia R
- Eugenio Luis Palazon Sanchez
- Ezzouine Hanane
- Fan Eddy
- Far\uedas Pamela A
- Fartoukh Muriel
- Fawkes Danielle A
- Ferguson Andrew
- Ferguson Niall D
- Fernandez Adriana M
- Fernandez Ruben O
- Fierro Jonathan M
- Floris Leda
- Follin Arnaud
- Fontenele Danielle C
- Formenti Paolo
- Forteza Catalina
- Fossali Tommaso
- Foti Giuseppe
- Fran\ue7a Ana G.
- Franco Nieves
- Francois Guy M
- Frati Elena
- Frendl Gyorgy
- Frigyik Aniko D
- Fusari Maurizio
- Futami Satoru
- G\uf3mez Pilar Ricart Aroa
- Gally Josette
- Ganesan Deeban
- Gao Yan
- Gao Yuan N
- Garcia Patricio H
- Gazenkampf Andrey A
- Gel\ue9e Bruno
- George Fernando G
- Ghazi Mohammed
- Gianinetto Hernan
- Giarratano Antonino
- Gillis Sarah
- Girgin Nermin Kelebek
- Gjedsted Jakob
- Glietsch Rita
- Goldgran-Toledano Dany
- Goligher Ewan C
- Gomaa Dina
- Gomaa Dina
- Gomes Rui M
- Gomez Antonio
- Gomez Pablo E
- Gomez-Flores Saira S
- Gon\ue7alves Claudio H
- Gonz\ue1lez Rojas Manuel A
- Gonz\ue1lez-Salamanca \uc1ngela
- Gonzalez Daniel R
- Gonzalez Marcos
- Goodson Jennifer C
- Gordo Federico
- Gosselin Ryan J
- Goubaux Bernard
- Graziani Romano
- Grelon Fabien
- Griffin Ruth O
- Grigoriev Evgeny
- Grijalba Carolina Quintana
- Grissom Colin K
- Gritsan Alexey I
- Grubissich Nicolas
- Gu\ue9rin Claude
- Gueret Renaud M
- Gurjar Mohan
- Guttormsen Anne B
- Hacking Danielle J
- Haddad Youssef
- Hadfield Dan
- Hagan Samantha J
- Han Hui
- Han Yi
- Hang Ai Y
- Hanlon Gabrielle C
- Harasawa Tomofumi
- Harrois Anatole
- Hashemian S. M
- Hashida Tomoaki
- He June
- He Zhenyang
- Hedlund Lars
- Heidari Farshad
- Heines Serge J
- Helleberg Johan
- Henderson Galen
- Hendrickson Carolyn M
- Herbrecht Jean-Etienne
- Hermosa Cecilia
- Hessell Robert J
- Heunks Leo M
- Heunks Leo M
- Higashijima Ushio
- Hirata Akira
- Holzgraefe Bernhard
- Honda Hiroyuki
- Honrubia Teresa
- Hopf Hans-Bernd F
- Hopkins Phil
- Hormis Anil P
- Hou Peter C
- Hou Sen-Kuang
- Hraiech Sami
- Hua Ma X
- Huang Qing Q
- Huang Xiao B
- Huerta Francisco P
- Huff Nidhi G
- Humphreys Sally K
- Hunt Anna
- Hurtado Javier
- Hurtado Javier
- Hurtado Javier
- Hutchison Robyn A
- Hutton Paula J
- Iba\uf1ez-Santacruz Marcos
- Ichikado Kazuya
- Ilutovich Santiago
- Imai Hiroshi
- Imma Vallverdu P
- Imperio Mar\ueda C
- Insaurralde Carolina S
- Inskip Deborah M
- Ioannou Nicholas
- Iotti Giorgio A
- Irvine Donald A
- Ismail Dina
- Ismail Dk Maizatul Aiman B Pg Hj
- Ismail Mehvish
- Ito Fumihito
- Izawa Masayo
- Jaafar Rola F
- Jakubowska Karina
- Jamaati Hamidreza
- Jarquin-Badiola Yves D
- Jassal Mandeep
- Jauregui Alejandra
- Javeed Areej
- Jiang Liangyan
- Jibaja Manuel
- Jimenez Antonio G
- Jochmans S\ue9bastien
- Jog Sameer A
- Jovanovic Bojan
- Judy Claine
- Jurado M\uaa Teresa
- Kadaba Varsha
- Kajtor Istvan
- Kakar Vivek
- Kalaitzis Evangelos
- Kalkoff Michael
- Kamel Ghassan
- Kameyama Yoshinobu
- Kamoun Salma
- Kander Thomas
- Kangelaris Kirsten N
- Kannan Santhana G
- Kashiwa Yozo
- Ke Serena
- Kedelv Hans
- Kennedy Barry
- Khebbeb Samy
- Kheir Fayez M
- Kimura Hiroyasu
- Kiourtzieva Ellada V
- Kitch Barrett T
- Knapman Karl M
- Knoll Jenny
- Knowles Serena
- Kol Mark R
- Kong Jing
- Koyama Kansuke
- Kra fler Jens
- Krstevski Amanda
- Kulkarni Shreedhar
- Kumar Alek
- Kurahashi Kiyoyasu
- Kusumoto Kohei
- L\uf3pez-Messa Juan B
- Laake Jon H
- Laake Jon Henrik
- Labarca Eduardo F
- Laffey John
- Laffey John G
- Lamb Keith D
- Lanspa Michael J
- Larsson Anders
- Larsson Niklas
- Le Moal Charlene
- Lebbinck Herve
- Lee Jarone
- Leemann-Refondini Corinne
- Leligdowicz Aleksandra
- Lemiale Virginie
- Lemus Jordana S
- Li Bin
- Li Qingdong
- Li Qiong J
- Li Wenwen
- Li Xiao L
- Li Xinyu
- Li Yimin
- Li Yuan Y
- Li-Xin Zhou
- Liew Kong Y
- Ling Long L
- Liu Haitao
- Liu Jian
- Liu Jing L
- Liu Kathleen D
- Liu Ling
- Llano Miguel
- Lohner Ralph
- Loiacono Flavia A
- Lombardo Andrea
- Lopez Esther Bermejo
- Lopez-Delgado Juan C
- Lora Fredy S
- Lora Pilar
- Lorente Jose A
- Lorente Maria del Carmen
- Lovazzano Pablo
- Lu Weihua
- Lu Yuanhua
- Luo Xiaoming
- Lynch Joan M
- M\ue1ca Jan
- Maazouzi Wajdi
- Macfadyen Rosaleen
- MacFie Caroline C
- Maddali Manoj V
- Maeyama Hiroki N
- Maghrabi Khalid A
- Magret Monica
- Mahto Heera L
- Mancebo Jordi
- Manoharan Venika
- Marcos Diego Pastor
- Marcu Alexandra
- Marin Julien
- Marin Maria C
- Martinez Felipe T
- Martinho Aurelia M
- Marum Susan M
- Massa Eleni V
- Mataloun Sergio
- Matamis Dimitrios
- Matsumoto Shuhei
- Mattei Alessia
- Matthay Michael A
- May Martin M
- Mcarthur Colin
- McAuley Daniel F
- McAuley Danny
- Mccalman Katie H
- Mckechnie Stuart
- Mckee Raymond
- Mckenna Toni E
- Mcleod Alex
- McNamee Lia
- McNamee Lia
- McNeil J Brennan
- Meaney Edel A
- Meco Basak Ceyda
- Meersseman Philippe
- Mehta Sangeeta
- Mejia Francisco Javier Flores
- Mellis Clare
- Memon Mohammedfaruk
- Mercat Alain
- Mesar Tomaz
- Mesar Tomaz
- Messias Ant\uf3nio M
- Messika Jonathan
- Meybohm Patrick
- Michel Philippe
- Millar Rebecca T
- Miller Jennene J
- Miller Russel R
- Milstein Cesar
- Mirabella Lucia
- Mizuguchi Ichiko
- Mochizuki Katsunori
- Mohammadreza Hashemian Seyed
- Mohr Nicholas M
- Mojoli Francesco
- Moles Silvia Iglesias
- Molin Alexandre
- Montanha Gustavo M
- Monteiro Jorge M
- Montero Laura Alvarez
- Monti Giacomo
- Montiel Gonz\ue1lez Raquel
- Montini Luca M
- Moock Marcelo
- Morin Anna-Karin
- Mortaza Satar
- Morton Alex
- Mouloudi Eleni K
- Moya David D Llinares
- Mukkera Satyanarayana Reddy
- Mustafa Ghanem M
- Muthuchellappan Radhakrishnan
- Nagy Eva O
- Nakamura Tomoyuki
- Namih Miriam
- Nassar Jr Antonio P
- Nasu Michitaka
- Navarra Leanlove
- Navarro Gonzalo
- Neal John
- Negoita Silvius Ioan
- Newby Lynette
- Nichol Alistair
- Nielsen Jonas
- Nielsen Jonas
- Niimi Daisuke
- Nin Nicolas
- Nishikawa Erin
- Nitta Kenichi
- Nobrega Danielle
- Noremark Kim Andre L
- Nu\uf1ez Edgardo
- Nunci Lordian
- Nunes Silvia L
- Nunomiya Shin
- Nutt Christopher
- Nygren Ingela
- O'Croinin Donall
- O'Muircheartaigh Aogan C
- Occhipinti Giovanna
- Oetting Trevor W
- Ogino Yasuaki
- Oikonomou Marina A
- Okane Sinead C
- Okuda Nao
- Oldroyd Matthew G
- Olga Moreno F
- Oliveira Bruno S
- Oneill Orla
- Ortiz Claudia A
- Oscanoa Fredy A Montes
- Osman Emilio M
- Oss Peteris
- Ouanes Islem
- Ould Zein Salem
- Ourailogloy Vasilis
- Owens Robert L
- Ozcelik Menekse
- Palaniswamy Vijayanand
- Palma Daniela M
- Palmese Salvatore
- Palo Jose Emmanuel
- Panarello Giovanna
- Papanikolaou Metaxia N
- Papavasilopoulou Theonymfi G
- Papazian Laurent
- Papurica Marius
- Para Luis Herrera
- Parhar Ken
- Parotto Matteo
- Pasanting-Lim Rossini Abbie B
- Patroniti Nicol\uf2
- Pattarino Ilaria
- Pecci Elisabetta
- Pellegrini Carlos A
- Pelletier Nicolas
- Pellicer Ana M
- Penuelas Oscar
- Pere Cesar P
- Pereira Carlos S
- Perez Cheng Meisy
- Perez Losada Elena
- Perez Manuel P
- Persson Linnea
- Pham T\ue0i
- Pham Tai
- Pham Tai
- Phan Nga T
- Piacentini Enrique A
- Pillai Suresh
- Pintado Maria C
- Piquilloud Lise
- Piquilloud Lise
- Piras Claudio
- Pittini Gustavo
- Plotnikow Gustavo A
- Poblano Manuel
- Poli Michela M
- Pota Vincenzo
- Pozo Norberto C
- Pozzi Matteo
- Preez Pieter D
- Prieto-Gonz\ue1lez Miryam
- Pronovost Antoine
- Protti Alessandro
- Qin Bingyu
- Qin Junping
- Qin Shu H
- Qin Tie H
- Qiu Haibo
- Qiu Haibo
- Raaijmakers Monique
- Rafael S\ue1nchez I
- Raimondi Ferdinando
- Raj Ashok S
- Ramakrishnan Nagarajan
- Ramesh Venkatapura J
- Ramirez-Alfaro Christian M
- Ramirez-Gutierrez Alvaro
- Ranero Jorge Luis
- Raponi Francesco
- Recio Noelia N
- Reschreiter Henrik
- Reske Andreas W
- Reuter Danielle
- Reynolds Claire
- Rezoagli Emanuele
- Rhayakar Rachana V
- Rialp Gemma
- Richecoeur Jack R
- Ricome Sylvie
- Rigaud Jean-Philippe
- Rinia Myra
- Rios Fernando
- Riss Katharina C
- Rittayamai Nuttapol
- Roberts Brigit L
- Robine Adrien
- Robles Joanne B
- Roche-Campo Ferran
- Rodgers Helen J
- Rodriguez Lucia L
- Rodriguez Ruben
- Rosa Jonas I
- Roser Tomas P
- Rossi Anna
- Roux Damien
- rowne Troy S B
- Rugonfalvi Szabolcs
- Ruiz Silvia Rodriguez
- Ruiz-Aguilar Antonio L
- Rylander Christian C
- Ryosuke Sekine
- S\ue1nchez Roc\uedo Manzano
- S\ue1nchez-Ballesteros Jes\ufas
- S\uf8reide Eldar
- Sabelnikovs Olegs
- Sable Safal D
- Saenz Mar\ueda G
- Saez Alejandro A
- Sagar Sudha V
- Saito Koji
- Saito Shigeki
- Salahuddin Nawal
- Salas Javier E
- Sales Vanessa M
- Samkaoui Nacer
- Sanchez Roberto Jimenez
- Sanchez-Hurtado Luis A
- Sanchez-Medina Jorge R
- Sandesc Dorel
- Santoli Francesco L
- Santos Cristina
- Sarma Aartik
- Sauvadet Elise P
- Savioli Monica
- Scafetti Sergio
- Sch\ue4fer Susanne
- Schi\uf6ler Fredrik
- Schiavone Vincenzo
- Schiavoni Lorenzo
- Schlichting Adam B
- Schneider Francis
- Schomer Ashley
- Schouten Jeroen A
- Schuetz Michael
- Schultz Marcus J
- Scott Christopher J
- Seasman Colette
- Seethala Raghu
- Sellors Gareth P
- Seoane-Quiroga Leticia
- Serra Carolina
- Serra Isabel M
- Setten Mariano G
- Seven Aylin
- Shah Bhagyesh
- Shao Huanzhang
- Shen Juanhong
- Shenoy Anitha
- Sher Sara
- Shimizu Kazuyoshi
- Shindhe Suresh
- Shinn Iii John O
- Shiozaki Kyoko
- Silesky Jimenez Juan I
- Silesky Juan
- Sim Malcolm
- Simon Philipp
- Simonis Fabienne D
- Sinha Pratik
- Sivashanmugave Mageswaran
- Sj\uf8b\uf8 Brit \uc5
- Sklienka Peter
- Smith Mark J
- Smith Oliver
- Soler Juan Alfonso
- Solis-Quesada Jaime E
- Sottiaux T
- Spadaro Savino
- Srinivasa Latha
- Stamou Electra E
- Stansil Frank
- Staudinger Thomas
- Steinberg Jack
- Stephenson Lorraine
- Stewart Richard
- Stigler William
- Sula Hektor
- Sun Renhua
- Surbatovic Maja
- Suzuki Hiroyuki
- Symmonds Sophie
- Szakmany Tamas
- Tabhan Edgardo
- Tabhan Edgardo E
- Tainter Christopher
- Takaba Akihiro
- Takada Tadaaki
- Takagi Shunsuke
- Tan Beatriz C
- Tanaka Hiroyuki
- Tang Rui
- Tapponnier Romain
- Tarantino Fabio
- Temprano Susana
- Terragni Pierpaolo
- Terzi Nicolas
- Thibault Sandrine
- Thomas Rajeev R Jha Matthew
- Thompson Marlus M
- Tibblin Anna Oscarsson
- Tinnirello Andrea
- Tiribelli Norberto
- Todeschini Manuel
- Tomescu Dana R
- Toribio D\ue1cil Parrilla
- Toth-Tarsoly Piroska
- Treanor Nuala
- Trinder T John
- Trinidad Olivia A
- Tulaimat Aiman
- Twohey Linda
- Uchiyama Akinori
- Ueda Takeshi
- Ueno Keiko
- Umbrello Michele
- Unnikrishnan Ramesh
- Uppalapati Aditya
- Van Haren Frank
- Van Wezel Hellen M
- Vargas Monica P
- Vascotto Ettore R
- Vasquez Daniela N
- Vega Luis D
- Veljovic Milic
- Venti Aaron
- Vercueil Andre
- Vermassen Joris
- Verstraete Rik
- Vessel Kathryn
- Villagomez Asisclo
- Villagomez Asisclo J
- Villamagua Boris G
- Villar Veronica
- Vinzio Mauricio
- Virgilio Corcoles G
- Vitale Michela N
- Volta Carlo A
- Wang Chunting
- Wang Chunxue
- Wang Hua X
- Wang Shou H
- Wang Wei
- Ware Lorraine B
- Warren Jessica
- Watanabe Eizo
- Watt Philip
- Welters Ingeborg D
- Wenham Tim
- Wessbergh Joanna
- Whitehead Christina
- Wickersham Nancy
- Willett Emma L
- Williams Alexandra J
- Williams Karen E
- Wise Matt P
- Wittebole Xavier
- Wong Helen S
- Woods Paul W
- Wrathall David W
- Wrigge Hermann
- Wu Ya Q
- Xin-Hua Qiang
- Xu Yonghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L
- Yeatts Dale J
- Yoshido Hector H Leon
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S
- Yuste Luis J
- Zacharas Giannis A
- Zacharowski Kai D
- Zani Gianluca
- Zantua Kim S
- Zazu Alan
- Zeggwagh Amine Ali
- Zeggwagh Amine Ali
- Zender Herv\ue9 O.
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y
- Zhao Huiying
- Zhao Jun
- Zhao Wendi
- Zhao Xian Y
- Zheng Ruiqiang
- Zhou Fa C
- Zhou Suming
- Zhu Bao H
- Zhu Wei H
- Zhuo Hanjing
- Zogheib Elie H
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
International audienceTwo acute respiratory distress syndrome (ARDS) subphenotypes (hyperinflammatory and hypoinflammatory) with distinct clinical and biological features and differential treatment responses have been identified using latent class analysis (LCA) in seven individual cohorts. To facilitate bedside identification of subphenotypes, clinical classifier models using readily available clinical variables have been described in four randomised controlled trials. We aimed to assess the performance of these models in observational cohorts of ARDS. Methods: In this observational, multicohort, retrospective study, we validated two machine-learning clinical classifier models for assigning ARDS subphenotypes in two observational cohorts of patients with ARDS: Early Assessment of Renal and Lung Injury (EARLI; n=335) and Validating Acute Lung Injury Markers for Diagnosis (VALID; n=452), with LCA-derived subphenotypes as the gold standard. The primary model comprised only vital signs and laboratory variables, and the secondary model comprised all predictors in the primary model, with the addition of ventilatory variables and demographics. Model performance was assessed by calculating the area under the receiver operating characteristic curve (AUC) and calibration plots, and assigning subphenotypes using a probability cutoff value of 0·5 to determine sensitivity, specificity, and accuracy of the assignments. We also assessed the performance of the primary model in EARLI using data automatically extracted from an electronic health record (EHR; EHR-derived EARLI cohort). In Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE; n=2813), a multinational, observational ARDS cohort, we applied a custom classifier model (with fewer variables than the primary model) to determine the prognostic value of the subphenotypes and tested their interaction with the positive end-expiratory pressure (PEEP) strategy, with 90-day mortality as the dependent variable. Findings: The primary clinical classifier model had an area under receiver operating characteristic curve (AUC) of 0·92 (95% CI 0·90–0·95) in EARLI and 0·88 (0·84–0·91) in VALID. Performance of the primary model was similar when using exclusively EHR-derived predictors compared with manually curated predictors (AUC=0·88 [95% CI 0·81–0·94] vs 0·92 [0·88–0·97]). In LUNG SAFE, 90-day mortality was higher in patients assigned the hyperinflammatory subphenotype than in those with the hypoinflammatory phenotype (414 [57%] of 725 vs 694 [33%] of 2088; p<0·0001). There was a significant treatment interaction with PEEP strategy and ARDS subphenotype (p=0·041), with lower 90-day mortality in the high PEEP group of patients with the hyperinflammatory subphenotype (hyperinflammatory subphenotype: 169 [54%] of 313 patients in the high PEEP group vs 127 [62%] of 205 patients in the low PEEP group; hypoinflammatory subphenotype: 231 [34%] of 675 patients in the high PEEP group vs 233 [32%] of 734 patients in the low PEEP group). Interpretation: Classifier models using clinical variables alone can accurately assign ARDS subphenotypes in observational cohorts. Application of these models can provide valuable prognostic information and could inform management strategies for personalised treatment, including application of PEEP, once prospectively validated. Funding: US National Institutes of Health and European Society of Intensive Care Medicine
Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome Insights from the LUNG SAFE Study
- Author
- Abe Toshikazu
- Abroug Fekri
- Abul Wahab Ahmad Yazid Bin HJ
- Adams John C
- Adamsson Richard O
- Adolfsson Anne
- Aguirre Janet S
- Aguirre-Bermeo Hernan
- Aisa Tharwat M
- Aisiku Imo
- Ajetunmobi Olaitan O
- Aker Mustafa
- Akyol Onat O
- Al Dorzi Hasan M
- Al Jabbary Ahmed S
- Albaiceta Guillermo M
- Albarrak Mohamad M
- Albiero Daniela
- Alda Rosa S
- Alejandro Risso
- Alexander Peter
- Alfonso Soler Juan
- Algaba Angela
- Aliaga Felipe A
- Alisasis Alain U
- Allan Russell M
- Almekhlafi Ghaleb
- Alonso Javier G
- Altaf Wahid
- Alvarez Montero Laura
- Alvarez Antonio M
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Mourad
- An Youzhong
- Andersen Finn H
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Angel Lorente Jose
- Antonelli Massimo M
- Antonio Ana Carolina P
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M
- Araujo Ana M
- Arizmendi Alfons
- Arnal Jean-Michel
- Aroa Gomez Pilar Ricart
- Artiga Maria Jose D
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio C
- Bailey Irene M
- Bailey Mathew B
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie M
- Barberet Guillaume
- Baron Rebecca M
- Baronia Arvind K
- Barratt-Due Andreas
- Barros Filipa M
- Barros Nelson C
- Batra Hitesh
- Battle Ceri E
- Bauer Philippe R
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu H
- Beduneau Gaetan
- Beegle Scott H
- Beitler Jeremy R
- Bellani Giacomo
- Beloncle Francois
- Ben Souissi Asma
- Benslama Abdellatif
- Beraldo Daniel O
- Berghe Caroline
- Berkelmans Frantz
- Bermejo Lopez Esther
- Besset Sebastien L
- Bettini Lisandro R
- Beuret Pascal
- Bezzi Marco G
- Bhardwaj Vallish K
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Biondi Rodrigo S
- Biscione Roberto R
- Black Colin S
- Blakeman Thomas C
- Blanco Javier
- Blasco Navalpotro Miguel Angel
- Bolon Stefan
- Borello Silvina A
- Borotto Erika E
- Botteri Marco
- Bouchoucha Slaheddine
- Boukhazna Messabi
- Bouw Maria J
- Boyd Owen
- Bramall Jon
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M
- Briquet Anais
- Brito Vania A
- Brizuela Matias
- Brochard Laurent
- Brochard Laurent Jean
- Broman Lars M
- Brown Samuel M
- Browne Troy S
- Bruhn Alejandro R
- Brunettini Barbara
- Bruns Monique M
- Buensuseso Juan A
- Bugedo Guillermo
- Buise Marc P
- Bulpa Pierre A
- Bumbasierevic Vesna
- Bumbasirevic Vesna
- Burtenshaw Andrew J
- Burtin Philippe
- Buzancais Gautier
- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
- Carbayo-Gorriz Cecilia
- Carboni Bisso Mariano
- Cardonnet Luis P
- Careless Jon P
- Carpentier Dorothee
- Carreno Nicolas G
- Carteaux Guillaume
- Casalena Paolo
- Casement Jonathan
- Castro Alejandro G
- Castro Silvia
- Catorze Nuno T
- Cazorla-Barranquero Francisca G
- Ceniceros-Barros Alexandra
- Cereijo Enrique
- Cerny Vladimir
- Cerrato Valeria
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman Rhiannon
- Chau Simon K
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry Shazia
- Christiansen Aage
- Cimic Nedim
- Cinnella Gilda
- Cirone Rob
- Citalan Johanna E
- Claraco-Vega Luis M
- Clarkson Kevin
- Clarkson Kevin P
- Claverias Laura
- Cohen Jason E
- Cole Jade M
- Collins Daniel
- Collyer Thomas
- Colombo Riccardo
- Combaux Daniele M
- Combes Alain
- Cooper Raphael
- Coppadoro Andrea
- Corneci Dan E
- Cortegiani Andrea
- Cortez Cesar A
- Coxo Cristina M
- Cracchiolo Andrea N
- Cranshaw Julius H
- Crapelli Giulia
- Crouch Daniel R
- Crova Philippe J
- Csabi Peter
- Curley Gerard
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric
- Daubin Cedric
- Daviaud Fabrice
- Davies Kyle G
- Dawson Heidi
- De Cima-Iglesias Sara
- de Gordoa Laura Ortiz-Ruiz
- De Haro Candelaria
- De Pablo Raul
- de Prost Nicolas
- Dean Michael N
- Declercq Pierre-Louis M
- Dector Dulce
- Deicas Alberto
- del Carmen Lorente Maria
- Dellamonica Jean
- Dellera Christian
- Delsing Angela
- Demirkiran Oktay
- Demoule Alexandre
- Dempaire Gabriel
- Dempsey Ged
- Dendane Tarek
- Depuydt Pieter
- Derman Suleyman S
- Di Tomasso Nora N
- Di Yu D
- Diaz Abad Ricardo
- Diaz-Rodriguez Esther
- Dive Alain M
- Dixit Subhal B
- Dolva Merete S
- Donnelly Adrian
- Dowling Anna T
- Doyen Denis
- Dres Martin
- Dreyer Kyle R
- Dunne Eimhin S
- Dupont Herve
- Duranteau Jacques
- Dwyer Rory
- Ebeid Alejandro
- Elatrous Souheil
- Elisabet Garcia M
- Elkhayari Mina
- Ellis Helen E
- Elmasri Mary
- Emmanuel Palo Jose
- Erbabacan Emre
- Eriksson Karin E
- Esteban Andres
- Estenssoro Elisa
- Esteve Francisco
- Estilita Joana M
- Estrella Claudia R
- Eugenio Luis Palazon Sanchez
- Ezzouine Hanane
- Fan Eddy
- Farias Pamela A
- Fartoukh Muriel
- Fawkes Danielle A
- Ferguson Andrew
- Ferguson Niall D
- Fernandes Antero do Vale
- Fernandez Adriana M
- Fernandez Ruben O
- Fierro Jonathan M
- Flores Mejia Francisco Javier
- Floris Leda
- Follin Arnaud
- Fontenele Danielle C
- Formenti Paolo
- Forteza Catalina
- Fossali Tommaso
- Foti Giuseppe
- Franca Ana G
- Franco Nieves
- Frati Elena
- Frendl Gyorgy
- Frigyik Aniko D
- Fusari Maurizio
- Futami Satoru
- Gallego Curto Elena
- Gally Josette
- Ganesan Deeban
- Gao Yan
- Gao Yuan N
- Garcia Patricio H
- Gattinoni Luciano
- Gazenkampf Andrey A
- Gelee Bruno
- George Fernando G
- Ghazi Mohammed
- Gianinetto Hernan
- Giarratano Antonino
- Gillis Sarah
- Girgin Nermin Kelebek
- Gjedsted Jakob
- Glietsch Rita
- Goldgran-Toledano Dany
- Goligher Ewan C
- Gomaa Dina
- Gomes Rui M
- Gomez Pablo E
- Gomez-Flores Saira S
- Goncalves Claudio H
- Gonzalez Rojas Manuel A
- Gonzalez Daniel R
- Gonzalez Marcos
- Gonzalez-Salamanca Angela
- Goodson Jennifer C
- Gordo Federico
- Gosselin Ryan J
- Goubaux Bernard
- Graziani Romano
- Grelon Fabien
- Griffin Ruth O
- Grigoriev Evgeny
- Grijalba Carolina Quintana
- Grissom Colin K
- Gritsan Alexey
- Grubissich Nicolas
- Gueret Renaud M
- Guerin Claude
- Gurjar Mohan
- Guttormsen Anne B
- Hacking Danielle J
- Haddad Youssef
- Hadfield Dan
- Hagan Samantha J
- Han Hui
- Han Yi
- Hang Ai Y
- Hanlon Gabrielle C
- Harasawa Tomofumi
- Harrois Anatole
- Hashemian Seyed Mohammadreza
- Hashemian SM
- Hashida Tomoaki
- He Zhenyang
- Hedlund Lars
- Heidari Farshad
- Heines Serge J
- Helleberg Johan
- Henderson Galen
- Herbrecht Jean-Etienne
- Hermosa Cecilia
- Herrera Para Luis
- Hessell Robert J
- Heunks Leo M
- Higashijima Ushio
- Hirata Akira
- Holzgraefe Bernhard
- Honda Hiroyuki
- Honrubia Teresa
- Hopf Hans-Bernd F
- Hopkins Phil
- Hormis Anil P
- Hou Peter C
- Hou Sen-Kuang
- Hraiech Sami
- Hua Ma X
- Huang Qing Q
- Huang Xiao B
- Huerta Francisco P
- Huff Nidhi G
- Humphreys Sally K
- Hunt Anna
- Hurtado Javier
- Hutchison Robyn A
- Hutton Paula J
- Ibanez-Santacruz Marcos
- Ichikado Kazuya
- Iglesias Moles Silvia
- Ilutovich Santiago
- Imai Hiroshi
- Imma Vallverdu P
- Imperio Maria C
- Insaurralde Carolina S
- Inskip Deborah M
- Ioannou Nicholas
- Iotti Giorgio A
- Irvine Donald A
- Ismail Dina
- Ismail Maizatul
- Ismail Mehvish
- Ito Fumihito
- Izawa Masayo
- Jaafar Rola F
- Jakubowska Karina
- Jamaati Hamidreza
- Jarquin-Badiola Yves D
- Jassal Mandeep
- Javeed Areej
- Jha Rajeev R
- Jiang Liangyan
- Jibaja Manuel
- Jimenez Sanchez Roberto
- Jimenez Antonio G
- Jochmans Sebastien
- Jog Sameer A
- Jovanovic Bojan
- Judy Claine
- Kadaba Varsha
- Kajtor Istvan
- Kakar Vivek
- Kalaitzis Evangelos
- Kalkoff Michael
- Kamel Ghassan
- Kameyama Yoshinobu
- Kamoun Salma
- Kander Thomas
- Kannan Santhana G
- Kashiwa Yozo
- Kedelv Hans
- Kennedy Barry
- Khebbeb Samy
- Kheir Fayez
- Kheir Fayez M
- Kimura Hiroyasu
- Kiourtzieva Ellada
- Kitch Barrett T
- Knapman Karl M
- Knoll Jenny
- Knowles Serena
- Kol Mark R
- Kong Jing
- Koyama Kansuke
- Krassler Jens
- Krstevski Amanda
- Kulkarni Shreedhar
- Kumar Alek
- Kurahashi Kiyoyasu
- Kusumoto Kohei
- Laake Jon H
- Laake Jon Henrik
- Labarca Eduardo F
- Laffey John
- Laffey John G
- Laffey John Gerard
- Lamb Keith D
- Lanspa Michael J
- Larsson Anders
- Larsson Niklas
- Le Moal Charlene
- Lebbinck Herve
- Lee Jarone
- Leemann-Refondini Corinne
- Lemiale Virginie
- Lemus Jordana S
- Leon Yoshido Hector H
- Li Bin
- Li Qingdong
- Li Qiong J
- Li Wenwen
- Li Xiao L
- Li Xinyu
- Li Yimin
- Li Yuan Y
- Liew Kong Y
- Ling Long L
- Liu Haitao
- Liu Jian
- Liu Jing L
- Liu Ling
- Llano Miguel
- Llinares Moya David D
- Lohner Ralph
- Loiacono Flavia A
- Lombardo Andrea
- Lopez-Delgado Juan C
- Lopez-Messa Juan B
- Lora Fredy S
- Lora Pilar
- Lorente Jose A
- Lovazzano Pablo
- Lu Weihua
- Lu Yuanhua
- Luis Ranero Jorge
- Luo Xiaoming
- Lynch Joan M
- Maazouzi Wajdi
- Maca Jan
- Macfadyen Rosaleen
- MacFie Caroline C
- Maeyama Hiroki N
- Maghrabi Khalid A
- Magret Monica
- Mahto Heera L
- Mancebo Jordi
- Manoharan Venika
- Manzano Sanchez Rocio
- Marcu Alexandra
- Marin Julien
- Marin Maria C
- Martinez Felipe T
- Martinho Aurelia M
- Marum Susan M
- Massa Eleni
- Mataloun Sergio
- Matamis Dimitrios
- Matsumoto Shuhei
- Mattei Alessia
- May Martin M
- McArthur Colin
- McAuley Daniel F
- McAuley Danny
- Mccalman Katie H
- Mckechnie Stuart
- Mckee Raymond
- Mckenna Toni E
- Mcleod Alex
- McNamee Lia
- Meaney Edel A
- Meco Basak Ceyda
- Meersseman Philippe
- Mehta Sangeeta
- Mellis Clare
- Memon Mohammedfaruk
- Mercat Alain
- Mesar Tomaz
- Messias Antonio M
- Messika Jonathan
- Meybohm Patrick
- Michel Philippe
- Millar Rebecca T
- Miller Jennene J
- Miller Russel R
- Mirabella Lucia
- Mizuguchi Ichiko
- Mochizuki Katsunori
- Mohr Nicholas M
- Mojoli Francesco
- Molin Alexandre
- Montanha Gustavo M
- Monteiro Jorge M
- Montes Oscanoa Fredy A
- Monti Giacomo
- Montiel Gonzalez Raquel
- Montini Luca M
- Montoiro Allue Raquel
- Moock Marcelo
- Morin Anna-Karin
- Mortaza Satar
- Morton Alex
- Mouloudi Eleni K
- Mukkera Satyanarayana Reddy
- Mustafa Ghanem M
- Muthuchellappan Radhakrishnan
- Nagy Eva O
- Nakamura Tomoyuki
- Namendys-Silva Silvio A
- Namih Miriam
- Nassar Jr Antonio P
- Nasu Michitaka
- Navarra Leanlove
- Navarro Gonzalo
- Neal John
- Negoita Silvius Ioan
- Neto Ary Serpa
- Newby Lynette
- Nichol Alistair
- Nielsen Jonas
- Niimi Daisuke
- Nin Nicolas
- Nin Nicolas
- Nishikawa Erin
- Nitta Kenichi
- Nobrega Danielle
- Noremark Kim Andre L
- Nunci Lordian
- Nunes Silvia L
- Nunez Edgardo
- Nunomiya Shin
- Nutt Christopher
- Nygren Ingela
- O'Croinin Donall
- O'Muircheartaigh Aogan C
- Occhipinti Giovanna
- Oetting Trevor W
- Ogino Yasuaki
- Oikonomou Marina A
- Okane Sinead C
- Okuda Nao
- Oldroyd Matthew G
- Olga Moreno F
- Oliveira Bruno S
- Oneill Orla
- Ortiz Claudia A
- Osman Emilio M
- Oss Peteris
- Ouanes Islem
- Ourailogloy Vasilis
- Owens Robert L
- Ozcelik Menekse
- Palaniswamy Vijayanand
- Palma Daniela M
- Palmese Salvatore
- Panarello Giovanna
- Papanikolaou Metaxia N
- Papavasilopoulou Theonymfi G
- Papazian Laurent
- Papurica Marius
- Parhar Ken
- Parotto Matteo
- Parrilla Toribio Dacil
- Pasanting-Lim Rossini Abbie B
- Pastor Marcos Diego
- Patroniti Nicolo
- Pattarino Pierpaolo Terragni Ilaria
- Pecci Elisabetta
- Pellegrini Carlos A
- Pelletier Nicolas
- Pellicer Ana M
- Pelosi Paolo
- Penuelas Oscar
- Pereira Carlos S
- Perez Cheng Meisy
- Perez Losada Elena
- Perez Cesar P
- Perez Manuel P
- Persson Linnea
- Pesenti Antonio
- Phan Nga T
- Piacentini Enrique A
- Pillai Suresh
- Pintado Maria C
- Piquilloud Lise
- Piras Claudio
- Pittini Gustavo
- Plotnikow Gustavo A
- Poblano Manuel
- Poli Michela M
- Pota Vincenzo
- Pozo Norberto C
- Pozzi Matteo
- Preez Pieter D
- Prieto-Gonzalez Miryam
- Pronovost Antoine
- Protti Alessandro
- Qiang Xin-Hua
- Qin Bingyu
- Qin Junping
- Qin Shu H
- Qin Tie H
- Qiu Haibo
- Raaijmakers Monique
- Rafael Sanchez
- Raimondi Ferdinando
- Raj Ashok S
- Ramakrishnan Nagarajan
- Ramesh Venkatapura J
- Ramirez Cervantes Mavy
- Ramirez-Alfaro Christian M
- Ramirez-Gutierrez Alvaro
- Rampinelli Adenilton M
- Ranieri Marco
- Raponi Francesco
- Recio Noelia N
- Reschreiter Henrik
- Reske Andreas W
- Reuter Danielle
- Reynolds Claire
- Rhayakar Rachana
- Rialp Gemma
- Richecoeur Jack R
- Ricome Sylvie
- Rigaud Jean-Philippe
- Rinia Myra
- Rios Fernando
- Riss Katharina C
- Rittayamai Nuttapol
- Roberts Brigit L
- Robine Adrien
- Robles Joanne B
- Roche-Campo Ferran
- Rodgers Helen J
- Rodriguez Ruiz Silvia
- Rodriguez Lucia L
- Rodriguez Ruben
- Rojas Alejandro
- Rosa Jonas
- Roser Tomas P
- Rossi Anna
- Roux Damien
- Rubenfeld Gordon
- Rugonfalvi Szabolcs
- Ruiz-Aguilar Antonio L
- Rylander Christian C
- Ryosuke Sekine
- Sabelnikovs Olegs
- Sable Safal D
- Saenz Maria G
- Saez Alejandro A
- Sagar Sudha
- Saito Koji
- Saito Shigeki
- Salahuddin Nawal
- Salas Javier E
- Sales Vanessa M
- Samkaoui Nacer
- Sanchez Cesar Palazon
- Sanchez-Ballesteros Jesus
- Sanchez-Hurtado Luis A
- Sanchez-Medina Jorge R
- Sandesc Dorel
- Santoli Francesco L
- Santos Cristina
- Sauvadet Elise P
- Savioli Monica
- Scafetti Sergio
- Schaefer Susanne
- Schiavone Vincenzo
- Schiavoni Lorenzo
- Schioler Fredrik
- Schlichting Adam B
- Schneider Francis
- Schomer Ashley
- Schouten Jeroen A
- Schuetz Michael
- Schultz Marcus J
- Schultz Marcus Josephus
- Scott Christopher J
- Seasman Colette
- Seethala Raghu
- Sellors Gareth P
- Seoane-Quiroga Leticia
- Serra Carolina
- Serra Isabel M
- Setten Mariano G
- Seven Aylin
- Shah Bhagyesh
- Shao Huanzhang
- Shen Juanhong
- Shenoy Anitha
- Sher Sara
- Shimizu Kazuyoshi
- Shindhe Suresh
- Shinn John O
- Shiozaki Kyoko
- Silesky Jimenez Juan
- Silesky Juan
- Sim Malcolm
- Simon Philipp
- Simonis Fabienne D
- Sivashanmugavel Mageswaran
- Sjobo Brit A
- Sklienka Peter
- Slutsky Arthur S
- Smith Mark J
- Smith Oliver
- Solis-Quesada Jaime E
- Soreide Eldar
- Sotillo Diaz Juan Carlos J
- Sottiaux Thierry
- Spadaro Savino
- Srinivasa Latha
- Stamou Electra E
- Staudinger Thomas
- Stephenson Lorraine
- Stewart Richard
- Stigler William
- Strauch Ulrich
- Sula Hektor
- Sun Renhua
- Surbatovic Maja
- Suzuki Hiroyuki
- Symmonds Sophie
- Szakmany Tamas
- Tabhan Edgardo
- Tabhan Edgardo E
- Tai Pham
- Tainter Christopher
- Takaba Akihiro
- Takada Tadaaki
- Takagi Shunsuke
- Tallet Alfonso Alec A
- Tan Beatriz C
- Tanaka Hiroyuki
- Tang Rui
- Tapponnier Romain
- Tarantino Fabio
- Temprano Susana
- Teresa Jurado Ma
- Terzi Nicolas
- Thibault Sandrine
- Thomas Matthew
- Thompson B Taylor
- Thompson Marlus M
- Tibblin Anna Oscarsson
- Tinnirello Andrea
- Tiribelli Norberto
- Todeschini Manuel
- Tomescu Dana R
- Toth-Tarsoly Piroska
- Treanor Nuala
- Trinder T John
- Trinidad Olivia A
- Tulaimat Aiman
- Twohey Linda
- Uchiyama Akinori
- Ueda Takeshi
- Ueno Keiko
- Umbrello Michele
- Unal Necmettin
- Unnikrishnan Ramesh
- Uppalapati Aditya
- van Haren Frank
- Van Haren Frank
- Van Wezel Hellen M
- Vargas Monica P
- Vascotto Ettore R
- Vasquez Daniela N
- Vega Luis D
- Veljovic Milic
- Venti Aaron
- Vercueil Andre
- Vermassen Joris
- Verstraete Rik
- Villagomez Asisclo
- Villagomez Asisclo J
- Villamagua Boris G
- Villar Veronica
- Vinzio Mauricio
- Virgilio Corcoles G
- Vitale Michela N
- Volta Carlo A
- Wang Chunting
- Wang Hua X
- Wang Shou H
- Wang Wei
- Warren Jessica
- Watanabe Eizo
- Watt Philip
- Welters Ingeborg D
- Wenham Tim
- Wessbergh Joanna
- Whitehead Christina
- Willett Emma L
- Williams Alexandra J
- Williams Karen E
- Wittebole Xavier
- Wong Helen S
- Woods Paul W
- Wrathall David W
- Wrigge Hermann
- Wu Ya Q
- Xu Yonghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L
- Yeatts Dale J
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S
- Yuste Luis J
- Zacharas Giannis A
- Zacharowski Kai D
- Zani Gianluca
- Zantua Kim S
- Zazu Alan
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Herve O
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y
- Zhao Huiying
- Zhao Jun
- Zhao Xian Y
- Zheng Ruiqiang
- Zhou Fa C
- Zhou Li-Xin
- Zhou Suming
- Zhu Bao H
- Zhu Wei H
- Zogheib Elie H
- Zumaran Aguilar Ronald
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/02/2019
- Field of study
BACKGROUND: Patients with initial mild acute respiratory distress syndrome are often underrecognized and mistakenly considered to have low disease severity and favorable outcomes. They represent a relatively poorly characterized population that was only classified as having acute respiratory distress syndrome in the most recent definition. Our primary objective was to describe the natural course and the factors associated with worsening and mortality in this population. METHODS: This study analyzed patients from the international prospective Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) who had initial mild acute respiratory distress syndrome in the first day of inclusion. This study defined three groups based on the evolution of severity in the first week: "worsening" if moderate or severe acute respiratory distress syndrome criteria were met, "persisting" if mild acute respiratory distress syndrome criteria were the most severe category, and "improving" if patients did not fulfill acute respiratory distress syndrome criteria any more from day 2. RESULTS: Among 580 patients with initial mild acute respiratory distress syndrome, 18% (103 of 580) continuously improved, 36% (210 of 580) had persisting mild acute respiratory distress syndrome, and 46% (267 of 580) worsened in the first week after acute respiratory distress syndrome onset. Global in-hospital mortality was 30% (172 of 576; specifically 10% [10 of 101], 30% [63 of 210], and 37% [99 of 265] for patients with improving, persisting, and worsening acute respiratory distress syndrome, respectively), and the median (interquartile range) duration of mechanical ventilation was 7 (4, 14) days (specifically 3 [2, 5], 7 [4, 14], and 11 [6, 18] days for patients with improving, persisting, and worsening acute respiratory distress syndrome, respectively). Admissions for trauma or pneumonia, higher nonpulmonary sequential organ failure assessment score, lower partial pressure of alveolar oxygen/fraction of inspired oxygen, and higher peak inspiratory pressure were independently associated with worsening. CONCLUSIONS: Most patients with initial mild acute respiratory distress syndrome continue to fulfill acute respiratory distress syndrome criteria in the first week, and nearly half worsen in severity. Their mortality is high, particularly in patients with worsening acute respiratory distress syndrome, emphasizing the need for close attention to this patient population.status: publishe
Death in hospital following ICU discharge: insights from the LUNG SAFE study
- Author
- Aage Christiansen
- Aaron Venti
- Abdellatif Benslama
- Adam B Schlichting
- Adenilton M Rampinelli
- Aditya Uppalapati
- Adrian Donnelly
- Adriana M Fernandez
- Adrien Robine
- Ahmed S Al Jabbary
- Ai Y Hang
- Aiman Tulaimat
- Akihiro Takaba
- Akinori Uchiyama
- Akira Hirata
- Alain Combes
- Alain M Dive
- Alain Mercat
- Alain U Alisasis
- Alan Zazu
- Alberto Deicas
- Alec A Tallet Alfonso
- Alejandro A Saez
- Alejandro G Castro
- Alejandro R Bruhn
- Alek Kumar
- Alessandro Protti
- Alessia Mattei
- Alex Mcleod
- Alex Morton
- Alexandra Ceniceros-Barros
- Alexandra J Williams
- Alexandra Marcu
- Alexandre Demoule
- Alexandre Molin
- Alexey I Gritsan
- Alfons Arizmendi
- Aline Ascoli
- Alistair Nichol
- Alma Cani
- Alvaro Ramirez-Gutierrez
- Amanda Krstevski
- Amine Ali Zeggwagh
- Amine Ali Zeggwagh
- Ana Carolina P Antônio
- Ana M Araujo
- Ana M Pellicer
- Anais Briquet
- Anatole Harrois
- Anders Aneman
- Anders Larsson
- Andre Vercueil
- Andrea Coppadoro
- Andrea Cortegiani
- Andrea Lombardo
- Andrea N Cracchiolo
- Andrea Tinnirello
- Andreas Barratt-Due
- Andreas W Reske
- Andres Esteban
- Andrew Ferguson
- Andrew J Burtenshaw
- Andrey A Gazenkampf
- Angela Delsing
- Aniko D Frigyik
- Anil P Hormis
- Anitha Shenoy
- Anna Hunt
- Anna Oscarsson Tibblin
- Anna Rossi
- Anna T Dowling
- Anna-Karin Morin
- Anne Adolfsson
- Anne B Guttormsen
- Antero do Vale Fernandes
- Antoine Pronovost
- Antonino Giarratano
- Antonio Artigas
- Antonio Braschi
- Antonio G Jimenez
- Antonio L Ruiz-Aguilar
- Antonio Pesenti
- Antonio Pesenti
- António M Alvarez
- António M Messias
- Aogan C O'Muircheartaigh
- Areej Javeed
- Ariel Chena
- Arnaud Follin
- Arthur S Slutsky
- Arvind K Baronia
- Ashley Schomer
- Ashok S Raj
- Asisclo J Villagomez
- Asisclo Villagomez
- Asma Ben Souissi
- Aurelia M Martinho
- Aylin Seven
- B Taylor Thompson
- Bao H Zhu
- Barbara Brunettini
- Barrett T Kitch
- Barry Kennedy
- Basak Ceyda Meco
- Beatriz C Tan
- Bellani Giacomo
- Bernard Goubaux
- Bernhard Holzgraefe
- Bhagyesh Shah
- Bin Li
- Bingyu Qin
- Bojan Jovanovic
- Boonsong Patjanasoontorn
- Boris G Villamagua
- BPg Hj Ismail
- Brigit L Roberts
- Brit Å Sjøbø
- Bruno Gelée
- Bruno S Oliveira
- Candelaria De Haro
- Carlo A Volta
- Carlos A Pellegrini
- Carlos S Pereira
- Carolina Quintana Grijalba
- Carolina S Insaurralde
- Carolina Serra
- Caroline Berghe
- Caroline C MacFie
- Catalina Forteza
- Cecilia Carbayo-Gorriz
- Cecilia Hermosa
- Ceri E Battle
- Cesar A Cortez
- Cesar Cesar Azevedo
- Cesar P Perez
- Charlene Le Moal
- Charles Gomersall
- Christian C Rylander
- Christian Dellera
- Christian M Ramirez-Alfaro
- Christina Whitehead
- Christopher J Scott
- Christopher Nutt
- Christopher Tainter
- Chunting Wang
- Claine Judy
- Claire Reynolds
- Clare Mellis
- Claude Guérin
- Claudia A Ortiz
- Claudia R Estrella
- Claudio H Gonçalves
- Claudio Piras
- Colette Seasman
- Colin K Grissom
- Colin Mcarthur
- Colin S Black
- Corcoles G Virgilio
- Corinne Leemann-Refondini
- Cristina M Coxo
- Cristina Santos
- Cédric Daubin
- Daisuke Niimi
- Dale J Yeatts
- Damien Roux
- Dan E Corneci
- Dan Hadfield
- Dana R Tomescu
- Daniel F McAuley
- Daniel O Beraldo
- Daniel R Crouch
- Daniel R Crouch
- Daniel R Gonzalez
- Daniel V Collins
- Daniela Albiero
- Daniela M Palma
- Daniela N Vasquez
- Daniele M Combaux
- Danielle A Fawkes
- Danielle C Fontenele
- Danielle J Hacking
- Danielle Nobrega
- Danielle Reuter
- Danny McAuley
- Dany Goldgran-Toledano
- David D Llinares Moya
- David W Wrathall
- Deborah M Inskip
- Deeban Ganesan
- Denis Doyen
- Diego Pastor Marcos
- Dimitrios Matamis
- Dina Gomaa
- Dina Gomaa
- Dina Ismail
- Dk Maizatul Aiman
- Donald A Irvine
- Donall O'Croinin
- Dorel Sandesc
- Dorothy M Breen
- Dorothée Carpentier
- Dulce Dector
- Dulce M Dector
- Dácil Parrilla Toribio
- Ed Bajwa
- Eddy Fan
- Edel A Meaney
- Edgardo E Tabhan
- Edgardo Nuñez
- Edgardo Tabhan
- Eduardo Beck
- Eduardo F Labarca
- Eimhin S Dunne
- Eizo Watanabe
- Eldar Søreide
- Electra E Stamou
- Elena Frati
- Elena Gallego Curto
- Elena Perez Losada
- Eleni K Mouloudi
- Eleni V Massa
- Elie H Zogheib
- Elisa Estenssoro
- Elisabetta Pecci
- Elise P Sauvadet
- Ellada V Kiourtzieva
- Emilio M Osman
- Emma L Willett
- Emre Erbabacan
- Enrique A Piacentini
- Enrique Cereijo
- Erika E Borotto
- Erin Nishikawa
- Esther Bermejo Lopez
- Esther Diaz-Rodriguez
- Ettore R Vascotto
- Eva O Nagy
- Evangelos Kalaitzis
- Evgeny Grigoriev
- Ewan C Goligher
- Fa C Zhou
- Fabiana Madotto
- Fabien Grelon
- Fabienne D Simonis
- Fabio Tarantino
- Fabrice Daviaud
- Fahd Amir
- Fan Zhang
- Fanny Klasen
- Farshad Heidari
- Fayez Kheir
- Fayez M Kheir
- Federico Gordo
- Fekri Abroug
- Felipe A Aliaga
- Felipe T Martinez
- Ferdinando Raimondi
- Fernando G George
- Fernando Rios
- Ferran Roche-Campo
- Filipa M Barros
- Finn H Andersen
- Flavia A Loiacono
- Francesca Rabboni
- Francesco L Santoli
- Francesco Mojoli
- Francesco Raponi
- Francis Schneider
- Francisca G Cazorla-Barranquero
- Francisco Esteve
- Francisco Javier Flores Mejia
- Francisco P Huerta
- Francois Beloncle
- Frank van Haren
- Frank van Haren
- Frantz Berkelmans
- Fredrik Schiöler
- Fredy A Montes Oscanoa
- Fredy S Lora
- Fumihito Ito
- Gabriel Démpaire
- Gabrielle C Hanlon
- Gaetan Béduneau
- Galen Henderson
- Garcia M Elisabet
- Gareth P Sellors
- Gautier Buzancais
- Ged Dempsey
- Gemma Rialp
- Gerard Curley
- Ghaleb Almekhlafi
- Ghanem M Mustafa
- Ghassan Kamel
- Giacomo Bellani
- Giacomo Bellani
- Giacomo Monti
- Gianluca Zani
- Giannis A Zacharas
- Gilda Cinnella
- Giorgio A Iotti
- Giovanna Occhipinti
- Giovanna Panarello
- Giulia Crapelli
- Giuseppe Foti
- Gonzalo Navarro
- Gordon Rubenfeld
- Gordon Rubenfeld
- Guillaume Barberet
- Guillaume Carteaux
- Guillermo Bugedo
- Guillermo M Albaiceta
- Gustavo A Plotnikow
- Gustavo M Montanha
- Gustavo Pittini
- Guy M Francois
- Gyorgy Frendl
- Haibo Qiu
- Haibo Qiu
- Haitao Liu
- Hamidreza Jamaati
- Hanane Ezzouine
- Hans Kedelv
- Hans-Bernd F Hopf
- Hasan M Al Dorzi
- Hector H Leon Yoshido
- Heera L Mahto
- Heidi Dawson
- Hektor Sula
- Helen E Ellis
- Helen J Rodgers
- Helen S Wong
- Helga Ceunen
- Hellen M Van Wezel
- Henrik Appelberg
- Henrik Reschreiter
- Hermann Wrigge
- Hernan Aguirre-Bermeo
- Hernan Gianinetto
- Herve Dupont
- Herve Lebbinck
- Hervé O Zender
- Hicham Balkhi
- Hiroki N Maeyama
- Hiroshi Imai
- Hiroyasu Kimura
- Hiroyuki Honda
- Hiroyuki Suzuki
- Hiroyuki Tanaka
- Hitesh Batra
- Hua X Wang
- Huanzhang Shao
- Hui Han
- Huiying Zhao
- Ichiko Mizuguchi
- Ilkay Ceylan
- Imed Chouchene
- Imo Aisiku
- Ingeborg D Welters
- Ingela Nygren
- Irene M Bailey
- Isabel M Serra
- Islem Ouanes
- Istvan Kajtor
- Jack R Richecoeur
- Jacob S Yumha
- Jacques Duranteau
- Jade M Cole
- Jaime E Solis-Quesada
- Jakob Gjedsted
- Jan Máca
- Janet S Aguirre
- Jarone Lee
- Jarone Lee
- Jarone Lee
- Jason E Cohen
- Javier Alvarez
- Javier Blanco
- Javier E Salas
- Javier G Alonso
- Javier Hurtado
- Javier Hurtado
- Javier Hurtado
- Jean Dellamonica
- Jean-Daniel Chiche
- Jean-Etienne Herbrecht
- Jean-Michel Arnal
- Jean-Michel Constantin
- Jean-Philippe Rigaud
- Jennene J Miller
- Jennifer C Goodson
- Jenny Knoll
- Jens Kraßler
- Jeremy R Beitler
- Jeroen A Schouten
- Jerome Biehler
- Jessica Warren
- Jesús Sánchez-Ballesteros
- Jian Liu
- Jing Kong
- Jing L Liu
- Joan M Lynch
- Joana M Estilita
- Joanna Wessbergh
- Joanne B Robles
- Johan Helleberg
- Johanna E Citalán
- John C Adams
- John G Laffey
- John G Laffey
- John Laffey
- John Neal
- John O Shinn Iii
- Jon Bramall
- Jon H Laake
- Jon Henrik Laake
- Jon P Careless
- Jonas I Rosa
- Jonas Nielsen
- Jonas Nielsen
- Jonathan Casement
- Jonathan Chelly
- Jonathan M Fierro
- Jonathan Messika
- Jordana S Lemus
- Jordi Mancebo
- Jorge Luis Ranero
- Jorge M Monteiro
- Jorge R Sanchez-Medina
- Jorge Synclair
- Joris Vermassen
- Jose A Lorente
- Jose Emmanuel Palo
- Josette Gally
- Juan A Buensuseso
- Juan Alfonso Soler
- Juan B López-Messa
- Juan C Lopez-Delgado
- Juan Carlos J Sotillo Diaz
- Juan I Silesky Jimenez
- Juan Silesky
- Juanhong Shen
- Julie Camsooksai
- Julien Marin
- Julio C Badie
- Julio Daldin
- Julius H Cranshaw
- Jun Zhao
- Junping Qin
- Kai Chen
- Kai D Zacharowski
- Kansuke Koyama
- Karen E Williams
- Karin E Eriksson
- Karina Jakubowska
- Karl M Knapman
- Katharina C Riss
- Katie H Mccalman
- Katsunori Mochizuki
- Kaushik Bhowmick
- Kazuya Ichikado
- Kazuyoshi Shimizu
- Keiko Ueno
- Keith D Lamb
- Ken Parhar
- Kenichi Nitta
- Kevin Clarkson
- Kevin P Clarkson
- Khalid A Maghrabi
- Kim Andre L Noremark
- Kim S Zantua
- Kiyoyasu Kurahashi
- Kohei Kusumoto
- Kohkichi Andoh
- Koji Saito
- Kong Y Liew
- Kyle G Davies
- Kyle R Dreyer
- Kyle R Dreyer
- Kyoko Shiozaki
- La Marsa
- Laffey John G.
- Lars Hedlund
- Lars M Broman
- Latha Srinivasa
- Laura Alvarez Montero
- Laura Claverias
- Laura Ortiz-Ruiz De Gordoa
- Laurence Dangers
- Laurent Brochard
- Laurent Papazian
- Leanlove Navarra
- Leda Floris
- Leo M Heunks
- Leo M Heunks
- Leticia Seoane-Quiroga
- Lia McNamee
- Lia McNamee
- Liangyan Jiang
- Linda Twohey
- Ling Liu
- Linnea Persson
- Lisandro R Bettini
- Lise Piquilloud
- Lise Piquilloud
- Long L Ling
- Lordian Nunci
- Loredana Baboi
- Lorenzo Schiavoni
- Lorraine Stephenson
- Luca Brazzi
- Luca M Montini
- Lucia L Rodriguez
- Lucia Mirabella
- Luciano Gattinoni
- Luis A Sanchez-Hurtado
- Luis D Vega
- Luis E Avila
- Luis Herrera Para
- Luis J Yuste
- Luis M Claraco-Vega
- Luis P Cardonnet
- Lynette Newby
- Ma X Hua
- Madotto Fabiana
- Mageswaran Sivashanmugavel
- Maja Surbatovic
- Malcolm Sim
- Mandeep Jassal
- Manuel A González Rojas
- Manuel Jibaja
- Manuel P Perez
- Manuel Poblano
- Manuel Todeschini
- Marc P Buise
- Marcelo Moock
- Marco Botteri
- Marco G Bezzi
- Marco Ranieri
- Marcos Gonzalez
- Marcos Ibañez-Santacruz
- Marcus J Schultz
- Maria C Marin
- Maria C Pintado
- Maria Del Carmen Lorente
- Maria J Bouw
- Maria Jose D Artiga
- Mariano Carboni Bisso
- Mariano G Setten
- Marina A Oikonomou
- Marius Papurica
- Mark J Smith
- Mark R Kol
- Marlus M Thompson
- Martin Dres
- Martin M May
- Mary Elmasri
- María C Imperio
- María G Saenz
- Masayo Izawa
- Massimo M Antonelli
- Mathew B Bailey
- Matias Brizuela
- Matt P Wise
- Matteo Parotto
- Matteo Pozzi
- Matthew G Oldroyd
- Mauricio Vinzio
- Maurizio Fusari
- Mavy Ramirez Cervantes
- McNicholas Bairbre
- Mehvish Ismail
- Meisy Perez Cheng
- Menekse Ozcelik
- Merete S Dolva
- Messabi Boukhazna
- Metaxia N Papanikolaou
- Michael J Lanspa
- Michael Kalkoff
- Michael N Dean
- Michael Schuetz
- Michela M Poli
- Michela N Vitale
- Michele Umbrello
- Michitaka Nasu
- Miguel Angel Blasco Navalpotro
- Miguel Llano
- Milic Veljovic
- Mina Elkhayari
- Miriam Namih
- Miryam Prieto-González
- Mohamad M Albarrak
- Mohammad Omar Faruq
- Mohammed Ghazi
- Mohammed V University
- Mohammedfaruk Memon
- Mohan Gurjar
- Monica Magret
- Monica P Vargas
- Monica Savioli
- Monique M Bruns
- Monique Raaijmakers
- Moreno F Olga
- Mourad Amor
- Muriel Fartoukh
- Mustafa Aker
- Myra Rinia
- Mª Teresa Jurado
- Nacer Samkaoui
- Nagarajan Ramakrishnan
- Nao Okuda
- Nawal Salahuddin
- Necmettin Ünal
- Nedim Cimic
- Nelson C Barros
- Nermin Kelebek Girgin
- Nga T Phan
- Niall D Ferguson
- Nicholas Ioannou
- Nicholas M Mohr
- Nicolas de Prost
- Nicolas Grubissich
- Nicolas Nin
- Nicolas Pelletier
- Nicolas Terzi
- Nicolás G Carreño
- Nicolás Nin
- Nicolò Patroniti
- Nidhi G Huff
- Nieves Franco
- Niklas Larsson
- Nobumasa Aoki
- Noelia N Recio
- Nora N Di Tomasso
- Norberto C Pozo
- Norberto Tiribelli
- Nuala Treanor
- Nuno T Catorze
- Nuttapol Rittayamai
- Oktay Demirkiran
- Olaitan O Ajetunmobi
- Olegs Sabelnikovs
- Oliver Beck
- Oliver Smith
- Olivia A Trinidad
- Onat O Akyol
- Orla Oneill
- Osamu Yamaguchi
- Oscar Penuelas
- Ovidiu H Bedreag
- Owen Boyd
- P Depuydt
- Pablo E Gomez
- Pablo Lovazzano
- Palazon Sanchez Cesar
- Palazon Sanchez Eugenio Luis
- Pamela A Farías
- Paolo Casalena
- Paolo Formenti
- Pascal Beuret
- Patricio H Garcia
- Patrick Meybohm
- Paul W Woods
- Paula J Hutton
- Pawel Andruszkiewicz
- Peter Alexander
- Peter C Hou
- Peter Csabi
- Peter Sklienka
- Peteris Oss
- Pham Tài
- Phil Hopkins
- Philip Watt
- Philipp Simon
- Philippe Burtin
- Philippe J Crova
- Philippe Meersseman
- Philippe Michel
- Philippe R Bauer
- Pierpaolo Terragni Ilaria Pattarino
- Pierre A Bulpa
- Pierre-Eric Danin
- Pierre-Louis M Declercq
- Pieter D Preez
- Pieter Depuydt
- Pilar Lora
- Pilar Ricart Aroa Gómez
- Piroska Toth-Tarsoly
- Pravin Amin
- Qiang Xin-Hua
- Qing Q Huang
- Qingchun Yao
- Qingdong Li
- Qiong J Li
- Rachana V Rhayakar
- Radhakrishnan Muthuchellappan
- Raghu Seethala
- Rajeev R JhaMatthew Thomas
- Ralph Lohner
- Raman Azad
- Ramesh Unnikrishnan
- Raphael Cooper
- Raquel Montiel Gonz Á Lez
- Raquel Montoiro Allue
- Raul De Pablo
- Raymond Mckee
- Rebecca M Baron
- Rebecca T Millar
- Renaud M Gueret
- Renhua Sun
- Rezoagli Emanuele
- Rhiannon Chapman
- Ricardo Diaz Abad
- Riccardo Colombo
- Richard O Adamsson
- Richard Stewart
- Rik Verstraete
- Risso V Alejandro
- Rita Glietsch
- Rob Cirone
- Robert J Hessell
- Robert L Owens
- Roberto Jimenez Sanchez
- Roberto R Biscione
- Robyn A Hutchison
- Rocío Manzano Sánchez
- Rodrigo S Biondi
- Rola F Jaafar
- Romain Tapponnier
- Romano Graziani
- Ronald Zumaran Aguilar
- Rongguo Yu
- Rory Dwyer
- Rosa S Alda
- Rosaleen Macfadyen
- Rossini Abbie B Pasanting-Lim
- Ruben O Fernandez
- Ruben Rodriguez
- Rui M Gomes
- Rui Tang
- Ruiqiang Zheng
- Russel R Miller
- Russell Chabanne
- Russell M Allan
- Ruth O Griffin
- Ryan J Gosselin
- S M Hashemian
- Safal D Sable
- Saira S Gomez-Flores
- Salem Ould Zein
- Sally K Humphreys
- Salma Kamoun
- Salvatore Palmese
- Samantha J Hagan
- Sameer A Jog
- Samuel M Brown
- Samy Khebbeb
- Sandrine Thibault
- Sangeeta Mehta
- Santhana G Kannan
- Santiago Ilutovich
- Sara Conti
- Sara De Cima-Iglesias
- Sara Sher
- Sarah Gillis
- Satar Mortaza
- Satoru Futami
- Satyanarayana Reddy Mukkera
- Savino Spadaro
- Scott H Beegle
- Sebastien L Besset
- Sekine Ryosuke
- Sen-Kuang Hou
- Serena Knowles
- Serge J Heines
- Sergio Canestrini
- Sergio Mataloun
- Sergio Scafetti
- Seyed Mohammadreza Hashemian
- Shailesh Bihari
- Shazia Choudry
- Shigeki Saito
- Shin Nunomiya
- Shou H Wang
- Shreedhar Kulkarni
- Shu H Qin
- Shuhei Matsumoto
- Shunsuke Takagi
- Silvia Castro
- Silvia Iglesias Moles
- Silvia L Nunes
- Silvia Rodriguez Ruiz
- Silvina A Borello
- Silvio A Ñamendys-Silva
- Silvius Ioan Negoita
- Simon K Chau
- Sinead C Okane
- Siu-Ming Au
- Slaheddine Bouchoucha
- Sophie Symmonds
- Souheil Elatrous
- Stefan Bolon
- Stuart Mckechnie
- Subhal B Dixit
- Sudha V Sagar
- Suleyman S Derman
- Suming Zhou
- Suresh Pillai
- Suresh Shindhe
- Susan M Marum
- Susana Temprano
- Susanne Schäfer
- Sylvie Ricome
- Szabolcs Rugonfalvi
- Sánchez I Rafael
- Sébastien Jochmans
- T John Trinder
- T Sottiaux
- Tadaaki Takada
- Takeshi Ueda
- Tamas Szakmany
- Tao Yu
- Tarek Dendane
- Teresa Honrubia
- Tharwat M Aisa
- Theonymfi G Papavasilopoulou
- Thomas Baltus
- Thomas C Blakeman
- Thomas Collyer
- Thomas Kander
- Thomas Staudinger
- Tie H Qin
- Tim Wenham
- Tomas P Roser
- Tomaz Mesar
- Tomaz Mesar
- Tommaso Fossali
- Tomoaki Hashida
- Tomofumi Harasawa
- Tomoyuki Nakamura
- Toni E Mckenna
- Toshikazu Abe
- Trevor W Oetting
- Troy S Browne
- Tài Pham
- Tài Pham
- Ulrich Strauch
- Ushio Higashijima
- Valeria I Cerrato
- Valerie M Banner-Goodspeed
- Vallish K Bhardwaj
- Vallverdu P Imma
- Vanessa M Sales
- Vania A Brito
- Varsha Kadaba
- Vasilis Ourailogloy
- Venika Manoharan
- Venkatapura J Ramesh
- Veronica Villar
- Vesna Bumbasierevic
- Vesna Bumbasirevic
- Vijayanand Palaniswamy
- Vincenzo Pota
- Vincenzo Schiavone
- Virginie Lemiale
- Vivek Kakar
- Vladimir Cerny
- Wahid Altaf
- Wajdi Maazouzi
- Waqar Kashif
- Wei H Zhu
- Wei Wang
- Weihua Lu
- Wenkui Yu
- Wenwen Li
- William Stigler
- Xavier Wittebole
- Xian Y Zhao
- Xiao B Huang
- Xiao L Li
- Xiaoming Luo
- Xing Y Zhang
- Xinyu Li
- Ya Q Wu
- Yaasen Arabi
- Yan Gao
- Yaseen M Arabi
- Yasuaki Ogino
- Yi Han
- Yimin Li
- Yonghao Xu
- Yoshihiro Yamaji
- Yoshinobu Kameyama
- Younsuck Koh
- Youssef Haddad
- Youzhong An
- Yozo Kashiwa
- Yu D Di
- Yuan N Gao
- Yuan Y Li
- Yuanhua Lu
- Yves D Jarquin-Badiola
- Zhe Zhai
- Zheng L Ye
- Zhenyang He
- Zhou Li-Xin
- Ángela Algaba
- Ángela González-Salamanca
- Ñ P Nassar Jr
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
ackground: To determine the frequency of, and factors associated with, death in hospital following ICU discharge to the ward.
Methods: The Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE study was an international, multicenter, prospective cohort study of patients with severe respiratory failure, conducted across 459 ICUs from 50 countries globally. This study aimed to understand the frequency and factors associated with death in hospital in patients who survived their ICU stay. We examined outcomes in the subpopulation discharged with no limitations of life sustaining treatments ('treatment limitations'), and the subpopulations with treatment limitations.
Results: 2186 (94%) patients with no treatment limitations discharged from ICU survived, while 142 (6%) died in hospital. 118 (61%) of patients with treatment limitations survived while 77 (39%) patients died in hospital. Patients without treatment limitations that died in hospital after ICU discharge were older, more likely to have COPD, immunocompromise or chronic renal failure, less likely to have trauma as a risk factor for ARDS. Patients that died post ICU discharge were less likely to receive neuromuscular blockade, or to receive any adjunctive measure, and had a higher pre- ICU discharge non-pulmonary SOFA score. A similar pattern was seen in patients with treatment limitations that died in hospital following ICU discharge.
Conclusions: A significant proportion of patients die in hospital following discharge from ICU, with higher mortality in patients with limitations of life-sustaining treatments in place. Non-survivors had higher systemic illness severity scores at ICU discharge than survivors
Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (Intensive Care Medicine, (2016), 42, 12, (1865-1876), 10.1007/s00134-016-4571-5)
- Author
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C.
- Adamsson Richard O.
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S.
- Aguirre-Bermeo Hernan
- Aiman Maizatul
- Aisa Tharwat M.
- Aisiku Imo
- Ajetunmobi Olaitan O.
- Aker Mustafa
- Akyol Onat O.
- Al Dorzi Hasan M.
- Al Jabbary Ahmed S.
- Albaiceta Guillermo M.
- Albarrak Mohamad M.
- Albiero Daniela
- Alda Rosa S.
- Alejandro Risso V.
- Alexander Peter
- Algaba Ángela
- Aliaga Felipe A.
- Alisasis Alain U.
- Allan Russell M.
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier G.
- Altaf Wahid
- Alvarez António M.
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Mourad
- An Youzhong
- Andersen Finn H.
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Antonelli Massimo M.
- Antônio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M.
- Arabi Yaseen M.
- Araujo Ana M.
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D.
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E.
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio C.
- Bailey Irene M.
- Bailey Mathew B.
- Bajwa Ednan K.
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie M.
- Barberet Guillaume
- Baron Rebecca M.
- Baronia Arvind K.
- Barratt-Due Andreas
- Barros Filipa M.
- Barros Nelson C.
- Batra Hitesh
- Battle Ceri E.
- Bauer Philippe R.
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu H.
- Beegle Scott H.
- Beitler Jeremy R.
- Bellani Giacomo
- Beloncle Francois
- Benslama Abdellatif
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans Frantz
- Besset Sebastien L.
- Bettini Lisandro R.
- Beuret Pascal
- Bezzi Marco G.
- Bhardwaj Vallish K.
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Biondi Rodrigo S.
- Biscione Roberto R.
- Bisso Mariano Carboni
- Black Colin S.
- Blakeman Thomas C.
- Blanco Javier
- Bolon Stefan
- Borello Silvina A.
- Borotto Erika E.
- Botteri Marco
- Bouchoucha Slaheddine
- Boukhazna Messabi
- Bouw Maria J.
- Boyd Owen
- Bramall Jon
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M.
- Briquet Anais
- Brito Vania A.
- Brizuela Matias
- Brochard Laurent
- Broman Lars M.
- Brown Samuel M.
- Browne Troy S.
- Bruhn Alejandro R.
- Brunettini Barbara
- Bruns Monique M.
- Buensuseso Juan A.
- Bugedo Guillermo
- Buise Marc P.
- Bulpa Pierre A.
- Bumbasierevic Vesna
- Bumbasirevic Vesna
- Burtenshaw Andrew J.
- Burtin Philippe
- Buzancais Gautier
- Béduneau Gaetan
- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
- Carbayo-Gorriz Cecilia
- Cardonnet Luis P.
- Careless Jon P.
- Carpentier Dorothée
- Carreño Nicolás G.
- Carteaux Guillaume
- Casalena Paolo
- Casement Jonathan
- Castro Alejandro G.
- Castro Silvia
- Catorze Nuno T.
- Cazorla-Barranquero Francisca G.
- Ceniceros-Barros Alexandra
- Cereijo Enrique
- Cerny Vladimir
- Cerrato Valeria I.
- Cervantes Mavy Ramirez
- Cesar Palazon Sanchez
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman Rhiannon
- Chau Simon K.
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Cheng Meisy Perez
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry Shazia
- Christiansen Aage
- Cimic Nedim
- Cinnella G
- Cinnella Gilda
- Cirone Rob
- Citalán Johanna E.
- Claraco-Vega Luis M.
- Clarkson Kevin
- Clarkson Kevin P.
- Claverias Laura
- Cohen Jason E.
- Cole Jade M.
- Collins Daniel V.
- Collyer Thomas
- Colombo Riccardo
- Combaux Daniele M.
- Combes Alain
- Conti Sara
- Cooper Raphael
- Coppadoro Andrea
- Corneci Dan E.
- Cortegiani Andrea
- Cortez Cesar A.
- Coxo Cristina M.
- Cracchiolo Andrea N.
- Cranshaw Julius H.
- Crapelli Giulia
- Crouch Daniel R.
- Crouch Daniel R.
- Crova Philippe J.
- Csabi Peter
- Curley Gerard
- Curto Elena Gallego
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric
- Daubin Cédric
- Daviaud Fabrice
- Davies Kyle G.
- Dawson Heidi
- De Cima-Iglesias Sara
- De Gordoa Laura Ortiz-Ruiz
- De Haro Candelaria
- De Pablo Raul
- de Prost Nicolas
- Dean Michael N.
- Declercq Pierre-Louis M.
- Dector Dulce
- Dector Dulce M.
- Deicas Alberto
- del Carmen Lorente Maria
- Dellamonica Jean
- Dellera Christian
- Delsing Angela
- Demirkiran Oktay
- Demoule Alexandre
- Dempsey Ged
- Dendane Tarek
- Depuydt P.
- Depuydt Pieter
- Derman Suleyman S.
- Di Tomasso Nora N.
- Di Yu D.
- Diaz-Rodriguez Esther
- Dive Alain M.
- Dixit Subhal B.
- do Vale Fernandes Antero
- Dolva Merete S.
- Donnelly Adrian
- Dowling Anna T.
- Doyen Denis
- Dres Martin
- Dreyer Kyle R.
- Dreyer Kyle R.
- Dunne Eimhin S.
- Dupont Herve
- Duranteau Jacques
- Dwyer Rory
- Démpaire Gabriel
- Ebeid Alejandro
- Elatrous Souheil
- Elisabet Garcia M.
- Elkhayari Mina
- Ellis Helen E.
- Elmasri Mary
- Erbabacan Emre
- Eriksson Karin E.
- Esteban Andres
- Estenssoro Elisa
- Esteve Francisco
- Estilita Joana M.
- Estrella Claudia R.
- Ezzouine Hanane
- Fan Eddy
- Fartoukh Muriel
- Farías Pamela A.
- Fawkes Danielle A.
- Ferguson Andrew
- Ferguson Niall D.
- Fernandez Adriana M.
- Fernandez Ruben O.
- Fierro Jonathan M.
- Floris Leda
- Follin Arnaud
- Fontenele Danielle C.
- Formenti Paolo
- Forteza Catalina
- Fossali Tommaso
- Foti Giuseppe
- Franco Nieves
- Francois Guy M.
- França Ana G.
- Frati Elena
- Frendl Gyorgy
- Frigyik Aniko D.
- Fusari Maurizio
- Futami Satoru
- Gally Josette
- Ganesan Deeban
- Gao Yan
- Gao Yuan N.
- Garcia Patricio H.
- Gattinoni Luciano
- Gazenkampf Andrey A.
- Gelée Bruno
- George Fernando G.
- Ghazi Mohammed
- Gianinetto Hernan
- Giarratano Antonino
- Gillis Sarah
- Girgin Nermin Kelebek
- Gjedsted Jakob
- Glietsch Rita
- Goldgran-Toledano Dany
- Goligher Ewan C.
- Gomaa Dina
- Gomaa Dina
- Gomes Rui M.
- Gomez Pablo E.
- Gomez-Flores Saira S.
- Gonzalez Daniel R.
- Gonzalez Marcos
- González Rojas Manuel A.
- González Raquel Montiel
- González-Salamanca Ángela
- Gonçalves Claudio H.
- Goodson Jennifer C.
- Gordo Federico
- Gosselin Ryan J.
- Goubaux Bernard
- Graziani Romano
- Grelon Fabien
- Griffin Ruth O.
- Grigoriev Evgeny
- Grijalba Carolina Quintana
- Grissom Colin K.
- Gritsan Alexey I.
- Grubissich Nicolas
- Gueret Renaud M.
- Gurjar Mohan
- Guttormsen Anne B.
- Guérin Claude
- Gómez Pilar Ricart Aroa
- Hacking Danielle J.
- Haddad Youssef
- Hadfield Dan
- Hagan Samantha J.
- Han Hui
- Han Yi
- Hang Ai Y.
- Hanlon Gabrielle C.
- Harasawa Tomofumi
- Harrois Anatole
- Hashemian Seyed Mohammadreza
- Hashida Tomoaki
- He Zhenyang
- Hedlund Lars
- Heidari Farshad
- Heines Serge J.
- Helleberg Johan
- Henderson Galen
- Herbrecht Jean-Etienne
- Hermosa Cecilia
- Hessell Robert J.
- Heunks Leo M.
- Higashijima Ushio
- Hirata Akira
- Holzgraefe Bernhard
- Honda Hiroyuki
- Honrubia Teresa
- Hopf Hans-Bernd F.
- Hopkins Phil
- Hormis Anil P.
- Hou Peter C.
- Hou Sen-Kuang
- Hraiech Sami
- Hua Ma X.
- Huang Qing Q.
- Huang Xiao B.
- Huerta Francisco P.
- Huff Nidhi G.
- Humphreys Sally K.
- Hunt Anna
- Hurtado Javier
- Hurtado Javier
- Hurtado Javier
- Hutchison Robyn A.
- Hutton Paula J.
- Ibañez-Santacruz Marcos
- Ichikado Kazuya
- Ilutovich Santiago
- Imai Hiroshi
- Imma Vallverdu P.
- Imperio María C.
- Insaurralde Carolina S.
- Inskip Deborah M.
- Ioannou Nicholas
- Iotti Giorgio A.
- Irvine Donald A.
- Ismail B. Pg Hj
- Ismail Dina
- Ismail Mehvish
- Ito Fumihito
- Izawa Masayo
- Jaafar Rola F.
- Jakubowska Karina
- Jamaati Hamidreza
- Jarquin-Badiola Yves D.
- Jassal Mandeep
- Javeed Areej
- JhaMatthew Thomas Rajeev R.
- Jiang Liangyan
- Jibaja Manuel
- Jimenez Antonio G.
- Jochmans Sébastien
- Jog Sameer A.
- John Trinder T.
- Jovanovic Bojan
- Judy Claine
- Jurado Mª Teresa
- Kadaba Varsha
- Kajtor Istvan
- Kakar Vivek
- Kalaitzis Evangelos
- Kalkoff Michael
- Kamel Ghassan
- Kameyama Yoshinobu
- Kamoun Salma
- Kander Thomas
- Kannan Santhana G.
- Kashiwa Yozo
- Kedelv Hans
- Kennedy Barry
- Khebbeb Samy
- Kheir Fayez
- Kheir Fayez M.
- Kimura Hiroyasu
- Kiourtzieva Ellada V.
- Kitch Barrett T.
- Knapman Karl M.
- Knoll Jenny
- Knowles Serena
- Kol Mark R.
- Kong Jing
- Koyama Kansuke
- Kraßler Jens
- Krstevski Amanda
- Kulkarni Shreedhar
- Kumar Alek
- Kurahashi Kiyoyasu
- Kusumoto Kohei
- Laake Jon Henrik
- Labarca Eduardo F.
- Laffey John G.
- Lamb Keith D.
- Lanspa Michael J.
- Larsson Anders
- Larsson Niklas
- Le Moal Charlene
- Lebbinck Herve
- Lee Jarone
- Lee Jarone
- Lee Jarone
- Leemann-Refondini Corinne
- Lemiale Virginie
- Lemus Jordana S.
- Leon Yoshido Hector H.
- Li Bin
- Li Qingdong
- Li Qiong J.
- Li Wenwen
- Li Xiao L.
- Li Xinyu
- Li Yimin
- Li Yuan Y.
- Li-Xin Zhou
- Liew Kong Y.
- Ling Long L.
- Liu Haitao
- Liu Jian
- Liu Jing L.
- Liu Ling
- Llano Miguel
- Llinares Moya David D.
- Lohner Ralph
- Loiacono Flavia A.
- Lombardo Andrea
- Lopez Esther Bermejo
- Lopez-Delgado Juan C.
- Lora Fredy S.
- Lora Pilar
- Lorente Jose A.
- Losada Elena Perez
- Lovazzano Pablo
- Lu Weihua
- Lu Yuanhua
- Luis Palazon Sanchez Eugenio
- Luo Xiaoming
- Lynch Joan M.
- López-Messa Juan B.
- Maazouzi Wajdi
- Macfadyen Rosaleen
- Macfie Caroline C.
- Madotto Fabiana
- Maeyama Hiroki N.
- Maghrabi Khalid A.
- Magret Monica
- Mahto Heera L.
- Mancebo Jordi
- Manoharan Venika
- Marcos Diego Pastor
- Marcu Alexandra
- Marin Julien
- Marin Maria C.
- Martinez Felipe T.
- Martinho Aurelia M.
- Marum Susan M.
- Massa Eleni V.
- Mataloun Sergio
- Matamis Dimitrios
- Matsumoto Shuhei
- Mattei Alessia
- May Martin M.
- Mcarthur Colin
- Mcauley Daniel F.
- Mcauley Danny
- Mcauley Danny
- Mccalman Katie H.
- Mckechnie Stuart
- Mckee Raymond
- Mckenna Toni E.
- Mcleod Alex
- Mcnamee Lia
- Meaney Edel A.
- Meco Basak Ceyda
- Meersseman Philippe
- Mehta Sangeeta
- Mejia Francisco Javier Flores
- Mellis Clare
- Memon Mohammedfaruk
- Mercat Alain
- Mesar Tomaz
- Mesar Tomaz
- Messias António M.
- Messika Jonathan
- Meybohm Patrick
- Michel Philippe
- Millar Rebecca T.
- Miller Jennene J.
- Miller Russel R.
- Mirabella L
- Mirabella Lucia
- Mizuguchi Ichiko
- Mochizuki Katsunori
- Mohr Nicholas M.
- Mojoli Francesco
- Moles Silvia Iglesias
- Molin Alexandre
- Montanha Gustavo M.
- Monteiro Jorge M.
- Montero Laura Alvarez
- Montes Oscanoa Fredy A.
- Monti Giacomo
- Montini Luca M.
- Moock Marcelo
- Morin Anna-Karin
- Mortaza Satar
- Morton Alex
- Mouloudi Eleni K.
- Mukkera Satyanarayana Reddy
- Mustafa Ghanem M.
- Muthuchellappan Radhakrishnan
- Máca Jan
- Nagy Eva O.
- Nakamura Tomoyuki
- Namih Miriam
- Nassar Antonio P.
- Nasu Michitaka
- Navalpotro Miguel Angel Blasco
- Navarra Leanlove
- Navarro Gonzalo
- Neal John
- Negoita Silvius Ioan
- Newby Lynette
- Nichol Alistair
- Nielsen Jonas
- Nielsen Jonas
- Niimi Daisuke
- Nin Nicolas
- Nishikawa Erin
- Nitta Kenichi
- Nobrega Danielle
- Noremark Kim Andre L.
- Nunci Lordian
- Nunes Silvia L.
- Nunomiya Shin
- Nutt Christopher
- Nuñez Edgardo
- Nygren Ingela
- Occhipinti Giovanna
- Oetting Trevor W.
- Ogino Yasuaki
- Oikonomou Marina A.
- Okane Sinead C.
- Okuda Nao
- Oldroyd Matthew G.
- Olga Moreno F.
- Oliveira Bruno S.
- Oneill Orla
- Ortiz Claudia A.
- Osman Emilio M.
- Oss Peteris
- Ouanes Islem
- Ourailogloy Vasilis
- Owens Robert L.
- Ozcelik Menekse
- O’Croinin Donall
- O’Muircheartaigh Aogan C.
- Palaniswamy Vijayanand
- Palma Daniela M.
- Palmese Salvatore
- Palo Jose Emmanuel
- Panarello Giovanna
- Papanikolaou Metaxia N.
- Papavasilopoulou Theonymfi G.
- Papazian Laurent
- Papurica Marius
- Para Luis Herrera
- Parhar Ken
- Parotto Matteo
- Pasanting-Lim Rossini Abbie B.
- Patroniti Nicolò
- Pattarino Pierpaolo Terragni Ilaria
- Pecci Elisabetta
- Pellegrini Carlos A.
- Pelletier Nicolas
- Pellicer Ana M.
- Penuelas Oscar
- Pereira Carlos S.
- Perez Cesar P.
- Perez Manuel P.
- Persson Linnea
- Pesenti Antonio
- Pham Tài
- Phan Nga T.
- Piacentini Enrique A.
- Pillai Suresh
- Pintado Maria C.
- Piquilloud Lise
- Piquilloud Lise
- Piras Claudio
- Pittini Gustavo
- Plotnikow Gustavo A.
- Poblano Manuel
- Poli Michela M.
- Pota Vincenzo
- Pozo Norberto C.
- Pozzi Matteo
- Preez Pieter D.
- Prieto-González Miryam
- Pronovost Antoine
- Protti Alessandro
- Qin Bingyu
- Qin Junping
- Qin Shu H.
- Qin Tie H.
- Qiu Haibo
- Raaijmakers Monique
- Rabboni Francesca
- Rafael Sánchez I.
- Raimondi Ferdinando
- Raj Ashok S.
- Ramakrishnan Nagarajan
- Ramesh Venkatapura J.
- Ramirez-Alfaro Christian M.
- Ramirez-Gutierrez Alvaro
- Rampinelli Adenilton M.
- Ranero Jorge Luis
- Ranieri Marco
- Raponi Francesco
- Recio Noelia N.
- Reschreiter Henrik
- Reske Andreas W.
- Reuter Danielle
- Reynolds Claire
- Rhayakar Rachana V.
- Rialp Gemma
- Richecoeur Jack R.
- Ricome Sylvie
- Rigaud Jean-Philippe
- Rinia Myra
- Rios Fernando
- Riss Katharina C.
- Rittayamai Nuttapol
- Roberts Brigit L.
- Robine Adrien
- Robles Joanne B.
- Roche-Campo Ferran
- Rodgers Helen J.
- Rodriguez Lucia L.
- Rodriguez Ruben
- Rosa Jonas I.
- Roser Tomas P.
- Rossi Anna
- Roux Damien
- Rubenfeld Gordon D.
- Rugonfalvi Szabolcs
- Ruiz Silvia Rodriguez
- Ruiz-Aguilar Antonio L.
- Rylander Christian C.
- Ryosuke Sekine
- Sabelnikovs Olegs
- Sable Safal D.
- Saenz María G.
- Saez Alejandro A.
- Sagar Sudha V.
- Saito Koji
- Saito Shigeki
- Salahuddin Nawal
- Salas Javier E.
- Sales Vanessa M.
- Samkaoui Nacer
- Sanchez Roberto Jimenez
- Sanchez-Hurtado Luis A.
- Sanchez-Medina Jorge R.
- Sandesc Dorel
- Santoli Francesco L.
- Santos Cristina
- Sauvadet Elise P.
- Savioli Monica
- Scafetti Sergio
- Schiavone Vincenzo
- Schiavoni Lorenzo
- Schiöler Fredrik
- Schlichting Adam B.
- Schneider Francis
- Schomer Ashley
- Schouten Jeroen A.
- Schuetz Michael
- Schultz Marcus J.
- Schäfer Susanne
- Scott Christopher J.
- Seasman Colette
- Seethala Raghu
- Sellors Gareth P.
- Seoane-Quiroga Leticia
- Serra Carolina
- Serra Isabel M.
- Service Gstt Severe Respiratory Failure
- Setten Mariano G.
- Seven Aylin
- Shah Bhagyesh
- Shao Huanzhang
- Shen Juanhong
- Shenoy Anitha
- Sher Sara
- Shimizu Kazuyoshi
- Shindhe Suresh
- Shinn Iii John O.
- Shiozaki Kyoko
- Silesky Jimenez Juan I.
- Silesky Juan
- Sim Malcolm
- Simon Philipp
- Simonis Fabienne D.
- Sivashanmugavel Mageswaran
- Sjøbø Brit Å.
- Sklienka Peter
- Slutsky Arthur S.
- Smith Mark J.
- Smith Oliver
- Soler Juan Alfonso
- Solis-Quesada Jaime E.
- Sotillo Diaz Juan Carlos J.
- Sottiaux T.
- Souissi Asma Ben
- Spadaro Savino
- Srinivasa Latha
- Stamou Electra E.
- Staudinger Thomas
- Stephenson Lorraine
- Stewart Richard
- Stigler William
- Strauch Ulrich
- Sula Hektor
- Sun Renhua
- Surbatovic Maja
- Suzuki Hiroyuki
- Symmonds Sophie
- Szakmany Tamas
- Sánchez Rocío Manzano
- Sánchez-Ballesteros Jesús
- Søreide Eldar
- Tabhan Edgardo
- Tabhan Edgardo E.
- Tainter Christopher
- Takaba Akihiro
- Takada Tadaaki
- Takagi Shunsuke
- Tallet Alfonso Alec A.
- Tan Beatriz C.
- Tanaka Hiroyuki
- Tang Rui
- Tapponnier Romain
- Tarantino Fabio
- Temprano Susana
- Terzi Nicolas
- Theresa Uhc Mother
- Thibault Sandrine
- Thompson B. Taylor
- Thompson Marlus M.
- Tibblin Anna Oscarsson
- Tinnirello Andrea
- Tiribelli Norberto
- Todeschini Manuel
- Tomescu Dana R.
- Toribio Dácil Parrilla
- Toth-Tarsoly Piroska
- Treanor Nuala
- Trinidad Olivia A.
- Tulaimat Aiman
- Twohey Linda
- Uchiyama Akinori
- Ueda Takeshi
- Ueno Keiko
- Umbrello Michele
- Unnikrishnan Ramesh
- Uppalapati Aditya
- van Haren Frank
- Van Wezel Hellen M.
- Vargas Monica P.
- Vascotto Ettore R.
- Vasquez Daniela N.
- Vega Luis D.
- Veljovic Milic
- Venti Aaron
- Vercueil Andre
- Vermassen Joris
- Verstraete Rik
- Villagomez Asisclo
- Villagomez Asisclo J.
- Villamagua Boris G.
- Villar Veronica
- Vinzio Mauricio
- Virgilio Corcoles G.
- Vitale Michela N.
- Volta Carlo A.
- Wang Chunting
- Wang Hua X.
- Wang Shou H.
- Wang Wei
- Warren Jessica
- Watanabe Eizo
- Watt Philip
- Welters Ingeborg D.
- Wenham Tim
- Wessbergh Joanna
- Whitehead Christina
- Willett Emma L.
- Williams Alexandra J.
- Williams Karen E.
- Wise Matt P.
- Wittebole Xavier
- Wong Helen S.
- Woods Paul W.
- Wrathall David W.
- Wrigge Hermann
- Wu Ya Q.
- Xin-Hua Qiang
- Xu Yonghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L.
- Yeatts Dale J.
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste Luis J.
- Zacharas Giannis A.
- Zacharowski Kai D.
- Zani Gianluca
- Zantua Kim S.
- Zazu Alan
- Zeggwagh Amine Ali
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé O.
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao Huiying
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa C.
- Zhou Suming
- Zhu Bao H.
- Zhu Wei H.
- Zogheib Elie H.
- Ñamendys-Silva Silvio A.
- Ünal Necmettin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 14/11/2017
- Field of study
The members of the LUNG SAFE Investigators and the ESICM Trials Group were provided in such a way that they could not be indexed as collaborators on PubMed. The publisher apologizes for this error
Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study
- Author
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C.
- Adamsson Richard O.
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S.
- Aguirre-Bermeo Hernan
- Aisa Tharwat M.
- Aisiku Imo
- Ajetunmobi Olaitan O.
- Aker Mustafa
- Akyol Onat O.
- Albaiceta Guillermo M.
- Albarrak Mohamad M.
- Albiero Daniela
- Alda Rosa S.
- Alejandro Risso V.
- Alexander Peter
- Alfonso Alec A. Tallet
- Algaba Ángela
- Aliaga Felipe A.
- Alisasis Alain U.
- Allan Russell M.
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier G.
- Altaf Wahid
- Alvarez António M.
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Mourad
- An Youzhong
- Andersen Finn H.
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Antonelli Massimo M.
- Antônio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M.
- Araujo Ana M.
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D.
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E.
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio C.
- Bailey Irene M.
- Bailey Mathew B.
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie M.
- Barberet Guillaume
- Baron Rebecca M.
- Baronia Arvind K.
- Barratt-Due Andreas
- Barros Filipa M.
- Barros Nelson C.
- Batra Hitesh
- Battle Ceri E.
- Bauer Philippe R.
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu H.
- Beegle Scott H.
- Beitler Jeremy R.
- Bellani Giacomo
- Beloncle Francois
- Benslama Abdellatif
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans Frantz
- Besset Sebastien L.
- Bettini Lisandro R.
- Beuret Pascal
- Bezzi Marco G.
- Bhardwaj Vallish K.
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Biondi Rodrigo S.
- Biscione Roberto R.
- Bisso Mariano Carboni
- Black Colin S.
- Blakeman Thomas C.
- Blanco Javier
- Bolon Stefan
- Borello Silvina A.
- Borotto Erika E.
- Bos Lieuwe D.
- Botteri Marco
- Bouchoucha Slaheddine
- Boukhazna Messabi
- Bouw Maria J.
- Boyd Owen
- Bramall Jon
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M.
- Briquet Anais
- Brito Vania A.
- Brizuela Matias
- Brochard Laurent
- Broman Lars M.
- Brown Samuel M.
- Browne Troy S.
- Bruhn Alejandro R.
- Brunettini Barbara
- Bruns Monique M.
- Buensuseso Juan A.
- Bugedo Guillermo
- Buise Marc P.
- Bulpa Pierre A.
- Bumbasierevic Vesna
- Bumbasirevic Vesna
- Burtenshaw Andrew J.
- Burtin Philippe
- Buzancais Gautier
- Béduneau Gaetan
- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
- Carbayo-Gorriz Cecilia
- Cardonnet Luis P.
- Careless Jon P.
- Carpentier Dorothée
- Carreño Nicolás G.
- Carteaux Guillaume
- Casalena Paolo
- Casement Jonathan
- Castro Alejandro G.
- Castro Silvia
- Catorze Nuno T.
- Cazorla-Barranquero Francisca G.
- Ceniceros-Barros Alexandra
- Cereijo Enrique
- Cerny Vladimir
- Cerrato Valeria I.
- Cervantes Mavy Ramirez
- Cesar Palazon Sanchez
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman Rhiannon
- Chau Simon K.
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Cheng Meisy Perez
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry Shazia
- Christiansen Aage
- Cimic Nedim
- Cinnella Gilda
- Cirone Rob
- Citalán Johanna E.
- Claraco-Vega Luis M.
- Clarkson Kevin
- Clarkson Kevin P.
- Claverias Laura
- Cohen Jason E.
- Cole Jade M.
- Collins Daniel V.
- Collyer Thomas
- Colombo Riccardo
- Combaux Daniele M.
- Combes Alain
- Cooper Raphael
- Coppadoro Andrea
- Corneci Dan E.
- Cortegiani Andrea
- Cortez Cesar A.
- Coxo Cristina M.
- Cracchiolo Andrea N.
- Cranshaw Julius H.
- Crapelli Giulia
- Crouch Daniel R.
- Crouch Daniel R.
- Crova Philippe J.
- Csabi Peter
- Curley Gerard
- Curto Elena Gallego
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric
- Daubin Cédric
- Daviaud Fabrice
- Davies Kyle G.
- Dawson Heidi
- de Cima-Iglesias Sara
- de Gordoa Laura Ortiz-Ruiz
- de Haro Candelaria
- de Pablo Raul
- de Prost Nicolas
- Dean Michael N.
- Declercq Pierre-Louis M.
- Dector Dulce
- Dector Dulce M.
- Deicas Alberto
- Del Carmen Lorente Maria
- Dellamonica Jean
- Dellera Christian
- Delsing Angela
- Demirkiran Oktay
- Demoule Alexandre
- Dempsey Ged
- Dendane Tarek
- Depuydt P.
- Depuydt Pieter
- Derman Suleyman S.
- Di Tomasso Nora N.
- Di Yu
- Diaz Juan Carlos J. Sotillo
- Diaz-Rodriguez Esther
- Dive Alain M.
- Dixit Subhal B.
- Do Vale Fernandes Antero
- Dolva Merete S.
- Donnelly Adrian
- Dorzi Hasan M. Al
- Dowling Anna T.
- Doyen Denis
- Dres Martin
- Dreyer Kyle R.
- Dreyer Kyle R.
- Dunne Eimhin S.
- Dupont Herve
- Duranteau Jacques
- Dwyer Rory
- Démpaire Gabriel
- Ebeid Alejandro
- Elatrous Souheil
- Elisabet Garcia M.
- Elkhayari Mina
- Ellis Helen E.
- Elmasri Mary
- Erbabacan Emre
- Eriksson Karin E.
- Esteban Andres
- Estenssoro Elisa
- Esteve Francisco
- Estilita Joana M.
- Estrella Claudia R.
- Ezzouine Hanane
- Fan Eddy
- Fan Eddy
- Fartoukh Muriel
- Farías Pamela A.
- Fawkes Danielle A.
- Ferguson Andrew
- Ferguson Niall D.
- Fernandez Adriana M.
- Fernandez Ruben O.
- Fierro Jonathan M.
- Floris Leda
- Fontenele Danielle C.
- Formenti Paolo
- Forteza Catalina
- Fossali Tommaso
- Foti Giuseppe
- Franco Nieves
- França Ana G.
- Frati Elena
- Frendl Gyorgy
- Frigyik Aniko D.
- Fusari Maurizio
- Futami Satoru
- Gally Josette
- Ganesan Deeban
- Gao Yan
- Gao Yuan N.
- Garcia Patricio H.
- Gattinoni Luciano
- Gazenkampf Andrey A.
- Gelée Bruno
- George Fernando G.
- Ghazi Mohammed
- Gianinetto Hernan
- Giarratano Antonino
- Gillis Sarah
- Girgin Nermin Kelebek
- Gjedsted Jakob
- Glietsch Rita
- Goldgran-Toledano Dany
- Goligher Ewan C.
- Gomaa Dina
- Gomaa Dina
- Gomes Rui M.
- Gomez Pablo E.
- Gomez-Flores Saira S.
- Gonzalez Daniel R.
- Gonzalez Marcos
- González Raquel Montiel
- González-Salamanca Ángela
- Gonçalves Claudio H.
- Goodson Jennifer C.
- Gordo Federico
- Gosselin Ryan J.
- Goubaux Bernard
- Graziani Romano
- Grelon Fabien
- Griffin Ruth O.
- Grigoriev Evgeny
- Grijalba Carolina Quintana
- Grissom Colin K.
- Gritsan Alexey I.
- Grubissich Nicolas
- Gueret Renaud M.
- Gurjar Mohan
- Guttormsen Anne B.
- Guérin Claude
- Gómez Pilar Ricart Aroa
- Hacking Danielle J.
- Haddad Youssef
- Hadfield Dan
- Hagan Samantha J.
- Han Hui
- Han Yi
- Hang Ai
- Hanlon Gabrielle C.
- Harasawa Tomofumi
- Harrois Anatole
- Hashemian S. M.
- Hashemian Seyed Mohammadreza
- Hashida Tomoaki
- He Zhenyang
- Hedlund Lars
- Heidari Farshad
- Heines Serge J.
- Helleberg Johan
- Henderson Galen
- Herbrecht Jean-Etienne
- Hermosa Cecilia
- Hessell Robert J.
- Heunks Leo M.
- Heunks Leo M.
- Higashijima Ushio
- Hirata Akira
- Holzgraefe Bernhard
- Honda Hiroyuki
- Honrubia Teresa
- Hopf Hans-Bernd F.
- Hopkins Phil
- Hormis Anil P.
- Hou Peter C.
- Hou Sen-Kuang
- Hraiech Sami
- Hua Ma
- Huang Qing Q.
- Huang Xiao B.
- Huerta Francisco P.
- Huff Nidhi G.
- Humphreys Sally K.
- Hunt Anna
- Hurtado Javier
- Hurtado Javier
- Hurtado Javier
- Hutchison Robyn A.
- Hutton Paula J.
- Ibañez-Santacruz Marcos
- Ichikado Kazuya
- Ilutovich Santiago
- Imai Hiroshi
- Imma Vallverdu P.
- Imperio María C.
- Inskip Deborah M.
- Ioannou Nicholas
- Iotti Giorgio A.
- Irvine Donald A.
- Ismail Dina
- Ismail Dk Maizatul Aiman B. Pg Hj
- Ismail Mehvish
- Ito Fumihito
- Izawa Masayo
- Jaafar Rola F.
- Jabbary Ahmed S. Al
- Jakubowska Karina
- Jamaati Hamidreza
- Jarquin-Badiola Yves D.
- Jassal Mandeep
- Javeed Areej
- Jiang Liangyan
- Jibaja Manuel
- Jimenez Antonio G.
- Jimenez Juan I. Silesky
- Jochmans Sébastien
- Jog Sameer A.
- Jovanovic Bojan
- Judy Claine
- Jurado Mª Teresa
- Kadaba Varsha
- Kajtor Istvan
- Kakar Vivek
- Kalaitzis Evangelos
- Kalkoff Michael
- Kamel Ghassan
- Kameyama Yoshinobu
- Kamoun Salma
- Kander Thomas
- Kannan Santhana G.
- Kashiwa Yozo
- Kedelv Hans
- Kennedy Barry
- Khebbeb Samy
- Kheir Fayez
- Kheir Fayez M.
- Kimura Hiroyasu
- Kiourtzieva Ellada V.
- Kitch Barrett T.
- Knapman Karl M.
- Knoll Jenny
- Knowles Serena
- Kol Mark R.
- Kong Jing
- Koyama Kansuke
- Kraßler Jens
- Krstevski Amanda
- Kulkarni Shreedhar
- Kumar Alek
- Kurahashi Kiyoyasu
- Kusumoto Kohei
- Laake Jon H.
- Laake Jon Henrik
- Labarca Eduardo F.
- Laffey John
- Laffey John G.
- Lamb Keith D.
- Lanspa Michael J.
- Larsson Anders
- Larsson Anders
- Larsson Niklas
- Le Moal Charlene
- Lebbinck Herve
- Lee Jarone
- Lee Jarone
- Lee Jarone
- Leemann-Refondini Corinne
- Lemiale Virginie
- Lemus Jordana S.
- Li Bin
- Li Qingdong
- Li Qiong J.
- Li Wenwen
- Li Xiao L.
- Li Xinyu
- Li Yimin
- Li Yuan Y.
- Li-Xin Zhou
- Liew Kong Y.
- Ling Long L.
- Liu Haitao
- Liu Jian
- Liu Jing L.
- Liu Ling
- Llano Miguel
- Lohner Ralph
- Loiacono Flavia A.
- Lombardo Andrea
- Lopez Esther Bermejo
- Lopez-Delgado Juan C.
- Lora Fredy S.
- Lora Pilar
- Lorente Jose A.
- Losada Elena Perez
- Lovazzano Pablo
- Lu Weihua
- Lu Yuanhua
- Luis Palazon Sanchez Eugenio
- Luo Xiaoming
- Lynch Joan M.
- López-Messa Juan B.
- Maazouzi Wajdi
- Macfadyen Rosaleen
- MacFie Caroline C.
- Madotto Fabiana
- Maeyama Hiroki N.
- Maghrabi Khalid A.
- Magret Monica
- Mahto Heera L.
- Mancebo Jordi
- Manoharan Venika
- Marcos Diego Pastor
- Marcu Alexandra
- Marin Julien
- Marin Maria C.
- Martinez Felipe T.
- Martinho Aurelia M.
- Marum Susan M.
- Massa Eleni V.
- Mataloun Sergio
- Matamis Dimitrios
- Matsumoto Shuhei
- Mattei Alessia
- May Martin M.
- Mcarthur Colin
- McAuley Daniel F.
- McAuley Daniel F.
- McAuley Danny
- McCalman Katie H.
- McKechnie Stuart
- Mckee Raymond
- Mckenna Toni E.
- Mcleod Alex
- McNamee Lia
- McNamee Lia
- Meaney Edel A.
- Meco Basak Ceyda
- Meersseman Philippe
- Mehta Sangeeta
- Mejia Francisco Javier Flores
- Mellis Clare
- Memon Mohammedfaruk
- Mercat Alain
- Mesar Tomaz
- Mesar Tomaz
- Messias António M.
- Messika Jonathan
- Meybohm Patrick
- Michel Philippe
- Millar Rebecca T.
- Miller Jennene J.
- Miller Russel R.
- Mirabella Lucia
- Mizuguchi Ichiko
- Mochizuki Katsunori
- Mohr Nicholas M.
- Mojoli Francesco
- Moles Silvia Iglesias
- Molin Alexandre
- Montanha Gustavo M.
- Monteiro Jorge M.
- Montero Laura Alvarez
- Monti Giacomo
- Montini Luca M.
- Moock Marcelo
- Morin Anna-Karin
- Mortaza Satar
- Morton Alex
- Mouloudi Eleni K.
- Moya David D. Llinares
- Mukkera Satyanarayana Reddy
- Mustafa Ghanem M.
- Muthuchellappan Radhakrishnan
- Máca Jan
- Nagy Eva O.
- Nakamura Tomoyuki
- Namih Miriam
- Nassar Antonio P.
- Nasu Michitaka
- Navalpotro Miguel Angel Blasco
- Navarra Leanlove
- Navarro Gonzalo
- Neal John
- Negoita Silvius Loan
- Newby Lynette
- Nichol Alistair
- Nielsen Jonas
- Nielsen Jonas
- Niimi Daisuke
- Nin Nicolas
- Nin Nicolás
- Nishikawa Erin
- Nitta Kenichi
- Nobrega Danielle
- Noremark Kim Andre L.
- Nunci Lordian
- Nunes Silvia L.
- Nunomiya Shin -
- Nutt Christopher
- Nuñez Edgardo
- Nygren Ingela
- Occhipinti Giovanna
- Oetting Trevor W.
- Ogino Yasuaki
- Oikonomou Marina A.
- Okuda Nao
- Oldroyd Matthew G.
- Olga Moreno F.
- Oliveira Bruno S.
- Ortiz Claudia A.
- Oscanoa Fredy A. Montes
- Osman Emilio M.
- Oss Peteris
- Ouanes Islem
- Ourailogloy Vasilis
- Owens Robert L.
- Ozcelik Menekse
- O’Croinin Donall
- O’Kane Sinead C.
- O’Muircheartaigh Aogan C.
- O’Neill Orla
- Palaniswamy Vijayanand
- Palma Daniela M.
- Palmese Salvatore
- Palo Jose Emmanuel
- Panarello Giovanna
- Papanikolaou Metaxia N.
- Papavasilopoulou Theonymfi G.
- Papazian Laurent
- Papurica Marius
- Para Luis Herrera
- Parhar Ken
- Parotto Matteo
- Pasanting-Lim Rossini Abbie B.
- Patroniti Nicolò
- Pattarino Pierpaolo Terragni Ilaria
- Pecci Elisabetta
- Pellegrini Carlos A.
- Pelletier Nicolas
- Pellicer Ana M.
- Penuelas Oscar
- Pereira Carlos S.
- Perez Cesar P.
- Perez Manuel P.
- Persson Linnea
- Pesenti Antonio
- Pham Tai
- Pham Tài
- Phan Nga T.
- Piacentini Enrique A.
- Pillai Suresh
- Pintado Maria C.
- Piquilloud Lise
- Piquilloud Lise
- Piras Claudio
- Pittini Gustavo
- Plotnikow Gustavo A.
- Poblano Manuel
- Poli Michela M.
- Pota Vincenzo
- Pozo Norberto C.
- Pozzi Matteo
- Preez Pieter D.
- Prieto-González Miryam
- Pronovost Antoine
- Protti Alessandro
- Qin Bingyu
- Qin Junping
- Qin Shu H.
- Qin Tie H.
- Qiu Haibo
- Qiu Haibo
- Raaijmakers Monique
- Rafael Sánchez I.
- Raimondi Ferdinando
- Raj Ashok S.
- Ramakrishnan Nagarajan
- Ramesh Venkatapura J.
- Ramirez-Alfaro Christian M.
- Ramirez-Gutierrez Alvaro
- Rampinelli Adenilton M.
- Ranero Jorge Luis
- Ranieri Marco
- Raponi Francesco
- Recio Noelia N.
- Reschreiter Henrik
- Reske Andreas W.
- Reuter Danielle
- Reynolds Claire
- Rhayakar Rachana V.
- Rialp Gemma
- Richecoeur Jack R.
- Ricome Sylvie
- Rigaud Jean-Philippe
- Rinia Myra
- Rios Fernando
- Riss Katharina C.
- Rittayamai Nuttapol
- Roberts Brigit L.
- Robine Adrien
- Robles Joanne B.
- Roche-Campo Ferran
- Rodgers Helen J.
- Rodriguez Lucia L.
- Rodriguez Ruben
- Rojas Manuel A. González
- Rosa Jonas I.
- Roser Tomas P.
- Rossi Anna
- Roux Damien
- Rubenfeld Gordon
- Rugonfalvi Szabolcs
- Ruiz Silvia Rodriguez
- Ruiz-Aguilar Antonio L.
- Rylander Christian C.
- Ryosuke Sekine
- Sabelnikovs Olegs
- Sable Safal D.
- Saenz María G.
- Saez Alejandro A.
- Sagar Sudha V.
- Saito Koji
- Saito Shigeki
- Salahuddin Nawal
- Salas Javier E.
- Sales Vanessa M.
- Samkaoui Nacer
- Sanchez Roberto Jimenez
- Sanchez-Hurtado Luis A.
- Sanchez-Medina Jorge R.
- Sandesc Dorel
- Santoli Francesco L.
- Santos Cristina
- Sauvadet Elise P.
- Savioli Monica
- Scafetti Sergio
- Schiavone Vincenzo
- Schiavoni Lorenzo
- Schiöler Fredrik
- Schlichting Adam B.
- Schneider Francis
- Schomer Ashley
- Schouten Jeroen A.
- Schuetz Michael
- Schultz Marcus J.
- Schäfer Susanne
- Scott Christopher J.
- Seasman Colette
- Seethala Raghu
- Sellors Gareth P.
- Seoane-Quiroga Leticia
- Serra Carolina
- Serra Isabel M.
- Setten Mariano G.
- Seven Aylin
- Shah Bhagyesh
- Shao Huanzhang
- Shen Juanhong
- Shenoy Anitha
- Sher Sara
- Shimizu Kazuyoshi
- Shindhe Suresh
- Shinn John O.
- Shiozaki Kyoko
- Silesky Juan
- Sim Malcolm
- Simon Philipp
- Simonis Fabienne D.
- Simonis Fabienne D.
- Sivashanmugavel Mageswaran
- Sjøbø Brit Å.
- Sklienka Peter
- Slutsky Arthur S.
- Smith Mark J.
- Smith Oliver
- Soler Juan Alfonso
- Solis-Quesada Jaime E.
- Sottiaux T.
- Souissi Asma Ben
- Spadaro Savino
- Srinivasa Latha
- Stamou Electra E.
- Staudinger Thomas
- Stephenson Lorraine
- Stewart Richard
- Stigler William
- Strauch Ulrich
- Sula Hektor
- Sun Renhua
- Surbatovic Maja
- Suzuki Hiroyuki
- Symmonds Sophie
- Szakmany Tamas
- Sánchez Rocío Manzano
- Sánchez-Ballesteros Jesús
- Søreide Eldar
- Tabhan Edgardo
- Tabhan Edgardo E.
- Tainter Christopher
- Takaba Akihiro
- Takada Tadaaki
- Takagi Shunsuke
- Tan Beatriz C.
- Tanaka Hiroyuki
- Tang Rui
- Tapponnier Romain
- Tarantino Fabio
- Temprano Susana
- Terzi Nicolas
- Thibault Sandrine
- Thomas Rajeev R. Jha Matthew
- Thompson B. Taylor
- Thompson Marlus M.
- Tibblin Anna Oscarsson
- Tinnirello Andrea
- Tiribelli Norberto
- Todeschini Manuel
- Tomescu Dana R.
- Toribio Dácil Parrilla
- Toth-Tarsoly Piroska
- Treanor Nuala
- Trinder T. John
- Trinidad Olivia A.
- Tulaimat Aiman
- Twohey Linda
- Uchiyama Akinori
- Ueda Takeshi
- Ueno Keiko
- Umbrello Michele
- Unnikrishnan Ramesh
- Uppalapati Aditya
- van Haren Frank
- van Haren Frank
- van Wezel Hellen M.
- Vargas Monica P.
- Vascotto Ettore R.
- Vasquez Daniela N.
- Vega Luis D.
- Veljovic Milic
- Venti Aaron
- Vercueil Andre
- Vermassen Joris
- Verstraete Rik
- Villagomez Asisclo
- Villagomez Asisclo J.
- Villamagua Boris G.
- Villar Veronica
- Vinzio Mauricio
- Virgilio Corcoles G.
- Vitale Michela N.
- Volta Carlo A.
- Wang Chunting
- Wang Hua X.
- Wang Shou H.
- Wang Wei
- Warren Jessica
- Watanabe Eizo
- Watt Philip
- Welters Ingeborg D.
- Wenham Tim
- Wessbergh Joanna
- Whitehead Christina
- Willett Emma L.
- Williams Alexandra J.
- Williams Karen E.
- Wise Matt P.
- Wittebole Xavier
- Wong Helen S.
- Woods Paul W.
- Wrathall David W.
- Wrigge Hermann
- Wrigge Hermann
- Wu Ya
- Xin-Hua Qiang
- Xu Yonghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L.
- Yeatts Dale J.
- Yoshido Hector H. Leon
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste Luis J.
- Zacharas Giannis A.
- Zacharowski Kai D.
- Zani Gianluca
- Zantua Kim S.
- Zazu Alan
- Zeggwagh Amine Ali
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé O.
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao Huiying
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa
- Zhou Suming
- Zhu Bao H.
- Zhu Wei H.
- Zogheib Elie H.
- Ñamendys-Silva Silvio A.
- Ünal Necmettin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification. Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24 h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Results: Of 2377 patients fulfilling the ARDS definition on the first day of ARDS (day 1) and receiving invasive mechanical ventilation, 503 (24%) no longer fulfilled the ARDS definition the next day, 52% of whom initially had moderate or severe ARDS. Higher tidal volume on day 1 of ARDS was associated with confirmed ARDS [OR 1.07 (CI 1.01–1.13), P = 0.035]. Hospital mortality was 38% overall, ranging from 31% in resolved ARDS to 41% in confirmed ARDS, and 57% in confirmed severe ARDS at day 2. In both resolved and confirmed ARDS, age, non-respiratory SOFA score, lower PEEP and P/F ratio, higher peak pressure and respiratory rate were each associated with mortality. In confirmed ARDS, pH and the presence of immunosuppression or neoplasm were also associated with mortality. The increase in area under the receiver operating curve for ARDS reclassification on day 2 was marginal. Conclusions: ARDS, whether resolved or confirmed at day 2, has a high mortality rate. ARDS reclassification at day 2 has limited predictive value for mortality. The substantial mortality risk in severe confirmed ARDS suggests that complex interventions might best be tested in this population. Trial Registration: ClinicalTrials.gov NCT02010073