Les atouts du texte théâtral en cours de FLE : le théâtre de l’absurde

L'objectif de ce mémoire est de mettre en évidence l'intérêt pédagogique de l'introduction d'activités et de projets théâtraux dans le cadre de l'enseignement et de l'apprentissage du français langue étrangère (FLE) afin de garantir un enseignement intégral et de qualité. La pratique théâtrale en classe est une forme d'immersion totale dans le monde francophone avec laquelle les élèves doivent aspirer à une communication globale qui intègre la voix, la transmission d'informations et de sentiments et la gestuelle. La société dans laquelle nous habitons, régie par la surinformation et la surexposition dans les réseaux sociaux, rend plus nécessaire que jamais d'encourager chez les élèves — reflet de cette société — l'esprit critique, l'engagement et la coopération, ainsi que de promouvoir la participation à des débats fondés sur le respect à la diversité et la tolérance. Notre proposition didactique, de nature multidisciplinaire, vise à utiliser le Théâtre de l'Absurde et, plus particulièrement, la pièce Rhinocéros, d'Eugène Ionesco, comme point de départ pour lutter contre l'aliénation et développer l'esprit critique des élèves alors qu'ils progressent dans l'apprentissage du français langue étrangère.La presente memoria tiene como objetivo destacar el interés pedagógico de la introducción de actividades y proyectos teatrales en el contexto de enseñanza-aprendizaje del francés como lengua extranjera con el fin de garantizar una enseñanza integral y de calidad. La práctica teatral en el aula constituye una forma de inmersión total en el mundo francófono con la que el alumnado debe aspirar a una comunicación global que incorpore la voz, la transmisión de información y sentimientos y la gestualidad. La sociedad en la que nos encontramos inmersos, regida por la sobreinformación y la sobreexposición en las redes sociales, hace que sea más necesario que nunca fomentar en el alumnado, reflejo de dicha sociedad, el pensamiento crítico, el compromiso y la cooperación, además de promover la participación en debates desde el respeto y la tolerancia. Nuestra propuesta didáctica, de carácter multidisciplinar, pretende valerse del teatro del absurdo y, más en concreto, de la obra Rinoceronte, de Eugène Ionesco, como punto de partida para luchar contra la alienación y desarrollar el pensamiento crítico en el alumnado al tiempo que este progresa en el aprendizaje de francés lengua extranjera.Máster en Profesor de Educación Secundaria Obligatoria y Bachillerato, Formación Profesional y Enseñanzas de Idioma

Supercritical fluid chromatography coupled to mass spectrometry: A valuable tool in food analysis

Producción CientíficaSupercritical fluid chromatography (SFC), although known for several decades, has undergone a growing interest in the last few years fueled by the introduction of modern instruments with improved robustness, and hyphenation to mass spectrometry (MS). This allows the analysis of trace compounds in complex samples with high selectivity, high sensitivity and in a short time, which has contributed to its increased use in the food analysis area. This work reviews the principal applications of SFC-MS in food analysis, highlighting the most important achievements

Mindfulness (MBI) en la formación continua y evaluación de la transferencia en la empresa pública

This research article presents the results of transfer to the workplace of the training received by workers of the Diputación de Sevilla. The training action is received as continuous training within the continuous training plans of the Diputación de Sevilla. Specifically, the face-to-face training action is a Mindfulness-Based Intervention (MBI): Mindfulness: cultivating full attention, with a duration of 28 hours. Several parameters of this MBI intervention have been analyzed, one of them the transfer of the knowledge acquired to professional and personal practice. The analyzed data show positive results in all the participants, so it can be affirmed that mindfulness training supposes an improvement in capacities such as patience, resilience, communication, problem solving, stress reduction, among other issues to be highlighted in the business climate and the mental health of the people who make it up.En este artículo de investigación, se presentan los resultados de transferencia al puesto de trabajo de la formación Mindfulness: Cultivando la atención plena, recibida por parte personas trabajadoras de la Diputación de Sevilla. La acción formativa es recibida como formación continua dentro de los planes de formación continua de la Diputación de Sevilla. Concretamente la acción formativa presencial, es una Intervención Basada en el Mindfulness (MBI): Mindfulness: cultivando la atención plena, con una duración de 28 horas. De esta intervención MBI se han analizado varios parámetros, uno de ellos la transferencia de los conocimientos adquiridos a la práctica profesional y personal. Los datos analizados desprenden resultados positivos en todas las personas participantes, por lo que se puede afirmar que la formación en mindfulness supone una mejora en capacidades como la paciencia, resiliencia, comunicación, resolución de problemas, reducción del estrés, entre otras cuestiones a destacar en el clima empresarial y en la salud mental de las personas que la componen.Universidad Pablo de Olavid

Cartas de Mário de Sá-Carneiro a Fernando Pessoa. Diciembre de 1912

Texto traducido por alumnos de las asignaturas "Lengua Portuguesa IV y traducción" y "Traducción de textos literarios pt - es", de la Universidad de Salamanca.Cartas de Mário de Sá-Carneiro a Fernando Pessoa. Noviembre de 191

GDNF gene is associated with tourette syndrome in a family study

Huertas-Fernández, Ismael et al.[Background] Tourette syndrome is a disorder characterized by persistent motor and vocal tics, and frequently accompanied by the comorbidities attention deficit hyperactivity disorder and obsessive-compulsive disorder. Impaired synaptic neurotransmission has been implicated in its pathogenesis. Our aim was to investigate the association of 28 candidate genes, including genes related to synaptic neurotransmission and neurotrophic factors, with Tourette syndrome.[Methods] We genotyped 506 polymorphisms in a discovery cohort from the United States composed of 112 families and 47 unrelated singletons with Tourette syndrome (201 cases and 253 controls). Genes containing significant polymorphisms were imputed to fine-map the signal(s) to potential causal variants. Allelic analyses in Tourette syndrome cases were performed to check the role in attention deficit hyperactivity disorder and obsessive-compulsive disorder comorbidities. Target polymorphisms were further studied in a replication cohort from southern Spain composed of 37 families and three unrelated singletons (44 cases and 73 controls).[Results] The polymorphism rs3096140 in glial cell line–derived neurotrophic factor gene (GDNF) was significant in the discovery cohort after correction (P = 1.5 × 10−4). No linkage disequilibrium was found between rs3096140 and other functional variants in the gene. We selected rs3096140 as target polymorphism, and the association was confirmed in the replication cohort (P = 0.01). No association with any comorbidity was found.[Conclusions] As a conclusion, a common genetic variant in GDNF is associated with Tourette syndrome. A defect in the production of GDNF could compromise the survival of parvalbumin interneurons, thus altering the excitatory/inhibitory balance in the corticostriatal circuitry. Validation of this variant in other family cohorts is necessary. © 2015 International Parkinson and Movement Disorder SocietyThis study was supported by New Jersey Center for Tourette Syndrome and Associated Disorders (NJCTS), the National Institute of Mental Health (R01MH092293), the Instituto de Salud Carlos III (PI10/01674, PI13/01461, PI14/01823), the Consejería de Economía, Innovación, Ciencia y Empresa de la Junta de Andalucía (CVI-02526, CTS-7685), the Consejería de Salud y Bienestar Social de la Junta de Andalucía (PI-0741/2010, PI-0437-2012, PI-0471-2013), the Sociedad Andaluza de Neurología, the Fundación Alicia Koplowitz, the Fundación Mutua Madrileña and the Jaques and Gloria Gossweiler Foundation. Ismael Huertas Fernández was supported by the “PFIS” program, Pilar Gómez Garre was supported by the “Miguel Servet” program, and Juan Francisco Martín Rodríguez was supported by the “Sara Borrell” program, all 3 from the Instituto de Salud Carlos III.Peer Reviewe

Differentiation of bee pollen samples according to the apiary of origin and harvesting period based on their amino acid content

Producción CientíficaBee pollen is currently one of the most widely consumed dietary supplements due to its high nutritional value and its potentially beneficial effects on health. Unfortunately, in recent years an increase in the fraudulent marketing of this product has been detected, mainly in terms of adulteration with pollen from other sources. This has made it necessary to seek new tools to ensure its authentication. Therefore, this study investigates the use of free amino acids as markers of the geographical origin and harvesting period of bee pollen. To demonstrate their potential as biomarkers, 72 samples from four apiaries (Pistacho, Tío Natalio, Monte and Fuentelahiguera), located in the same geographical area (Marchamalo, Guadalajara, Spain), were analyzed by liquid chromatography-fluorescence detection, with the data obtained undergoing canonical discriminant analysis. Variable amounts and numbers of free amino acids were found in the samples analyzed; proline predominated in all of them, in a concentration range of 298–569989 mg/kg. The differences observed in amino acid composition could be attributed to the flowering plants from which the bee pollen samples originated. In addition, it was possible to statistically assign over 75% of the samples to the corresponding apiary of origin, the best results being obtained for the Fuentelahiguera and Tío Natalio apiaries (100%); this classification was even superior in the case of the harvesting periods, as more than 90% of the samples were correctly assigned, and in one period (June) a 100% rate was obtained.Ministerio de Economía, Industria y Competitividad (projects RTA 2015-00013-C03-01 and RTA 2015-00013-C03-03

Nonstoichiometry driven ferromagnetism in double perovskite La2Ni1-xMn1+ xO6 insulating thin films

This is an open access article published under an ACS AuthorChoice License. See Standard ACS AuthorChoice/Editors' Choice Usage AgreementIn this work we report on the epitaxial growth of LaNiMnO double perovskite thin films on top of (001) oriented SrTiO substrates by RF magnetron sputtering. The influence of oxygen pressure (P O) and growth temperature on the microstructure, stoichiometry of the films, and magnetic and transport properties is thoroughly investigated. It is found that high oxygen pressure promotes the growth of stoichiometric films, with a Ni/Mn ratio almost equal to 1. However, these films exhibit poor ferromagnetic properties with respect to the expected optimum values corresponding to ferromagnetic ordering mediated by superexchange interaction between Mn and Ni according to the Goodenough-Kanamori rules. Most interestingly, films grown at low P O exhibit Ni/Mn ratios below 1, but ferromagnetic properties close to the optimal ones. The valence balance between Ni and Mn ions in nonstoichiometric sample has been elucidated by X-ray absorption spectroscopy. The results indicate that Ni deficiency plays a crucial role in the puzzling insulating ferromagnetic behavior observed in nonstoichiometric samples

Deep Molecular Characterization of Milder Spinal Muscular Atrophy Patients Carrying the c.859G>C Variant in SMN2

Next-generation sequencing; Phenotype–genotype correlations; Spinal muscular atrophySeqüenciació de nova generació; Correlacions fenotip-genotip; Atròfia muscular espinalSecuenciación de nueva generación; Correlaciones fenotipo-genotipo; Atrofia muscular espinalSpinal muscular atrophy (SMA) is a severe neuromuscular disorder caused by biallelic loss or pathogenic variants in the SMN1 gene. Copy number and modifier intragenic variants in SMN2, an almost identical paralog gene of SMN1, are known to influence the amount of complete SMN proteins. Therefore, SMN2 is considered the main phenotypic modifier of SMA, although genotype–phenotype correlation is not absolute. We present eleven unrelated SMA patients with milder phenotypes carrying the c.859G>C-positive modifier variant in SMN2. All were studied by a specific NGS method to allow a deep characterization of the entire SMN region. Analysis of two homozygous cases for the variant allowed us to identify a specific haplotype, Smn2-859C.1, in association with c.859G>C. Two other cases with the c.859G>C variant in their two SMN2 copies showed a second haplotype, Smn2-859C.2, in cis with Smn2-859C.1, assembling a more complex allele. We also identified a previously unreported variant in intron 2a exclusively linked to the Smn2-859C.1 haplotype (c.154-1141G>A), further suggesting that this region has been ancestrally conserved. The deep molecular characterization of SMN2 in our cohort highlights the importance of testing c.859G>C, as well as accurately assessing the SMN2 region in SMA patients to gain insight into the complex genotype–phenotype correlations and improve prognostic outcomes.This research was funded by grants from Biogen (ESP-SMG-17-11256), Roche, GaliciAME and Spanish Instituto de Salud Carlos III, Fondo de Investigaciones Sanitarias and co-funded with ERDF funds (grant no. FIS PI18/000687). A grant from Horizon 2020 IMI2 Screen4Care is acknowledged by E.B., and L.T., E.F.T., R.J., J.S., L.C.-C., F.M., E.B., and L.T. are members of the ERN NMD Network for Rare Diseases. E.F.T. is a member of the ERN ITHACA Network for Rare Diseases

Risk of suicide in households threatened with eviction: the role of banks and social support

Background: One of the greatest effects of the financial crisis in Spain has been the enormous increase in the number of evictions. Several studies have shown the association of evictions with different aspects of the physical and mental health. Furthermore, evictions have been associated with an increased risk of suicide. Our objective was to evaluate the risk of suicide among victims of eviction and investigate whether it is associated with specific characteristics of households and interviewees, the eviction process and social support, and health needs. Results: Almost half of the sample (46.7%) were at low (11.8%), moderate (16.9%), or high suicide risk (17.9%). Household and interviewee features had a limited association with suicide risk. On the contrary, the risk of suicide is greater with a longer exposure to the eviction process. In addition, threatening phone calls from banks increased significantly the risk of suicide, especially among men. Suicide risk was also associated with low social support, especially among women. Interviewees at risk of suicide received more help from nongovernmental organizations than those who were not at risk. In interviewees at risk, the main unmet needs were emotional and psychological help, especially in men. A high percentage of those at risk of suicide declare having large unmeet health needs. Finally, there was a tendency among the evicted at risk of suicide to visit emergency room and primary care more often than those not at risk, especially among women. Conclusions: To our knowledge, this is the first study showing that when banks adopt a threatening attitude, suicide risk increases among the evicted. As hypothesized, when the evicted felt socially supported, suicide risk decreased. Emotional help was the main mediator of suicide risk and the main unmet need, especially among me

Diseño de un entorno de edición y publicación de metadatos por medio de herramientas masivas de importación, basado en la integración de ArcGis y Geonetwork

Hi ha una utilització de gran quantitat d'informació geogràfica en el marc de l'ETC-SIA i de la resta dels projectes del grup Interfase, i a causa d'això s'ha presentat la necessitat de catalogar i documentar correctament la informació. Per al desenvolupament del projecte es va tenir en compte quatre fases diferents les quals van ser l'anàlisi, disseny del programari, desenvolupament i implementació. Quant al desenvolupament i implementació és important ressaltar que el fet anteriorment va ser realitzat per mitjà d'un script en llenguatge Python, es tracta d'un llenguatge de programació multi paradigma, ja que suporta orientació a objectes, programació imperativa i en menor mesura, programació funcionalExiste una utilización de gran cantidad de información geográfica en el marco del ETC-SIA y del resto de los proyectos del grupo Interfase, y debido a esto se ha presentado la necesidad de catalogar y documentar correctamente la información. Para el desarrollo del proyecto se tuvo en cuenta cuatro fases diferentes las cuales fueron el análisis, diseño del software, desarrollo e implementación. En cuanto al desarrollo e implementación es importante resaltar que lo hecho anteriormente fue realizado por medio de un script en lenguaje Python, se trata de un lenguaje de programación multiparadigma, ya que soporta orientación a objetos, programación imperativa y en menor medida, programación funciona