1,930 research outputs found

    Hiking to the "Real" Northernmost Point. Performing Identiy on the way to Knivskjellodden

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    Summary: Over the last decade hiking tourism has grown in Norway. This is exemplified by the increasing numbers of tourists that visits Trolltunga, Prekestolen and Kjerag. These are the most prominent examples, which appears to be part of a larger trend. Knivskjellodden has likewise, seen a rise in visitor numbers over the last decade. This aim of this thesis is to build an understanding of the meaning people attach to their hike to Knivskjellodden. This phenomenon will be explored through Edensor´s (2000, 2001, 2007) theories on performance in tourism. During the analysis it is reflected upon how identity is constructed through performances where `self´ is attached to activity, places and a certain way of traveling

    Phase transition and dynamical-parameter method in U(1) gauge theory

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    Monte Carlo simulations of the 4-dimensional compact U(1) lattice gauge theory in the neighborhood of the transition point are made difficult by the suppression of tunneling between the phases, which becomes very strong as soon as the volume of the lattice grows to any appreciable size. This problem can be avoided by making the monopole coupling a dynamical variable. In this manner one can circumvent the tunneling barrier by effectively riding on top of the peaks in the energy distribution which meet for sufficiently large monopole coupling. Here we present an efficient method for determining the parameters needed for this procedure, which can thus be implemented at low computational cost also on large lattices. This is particularly important for a reliable determination of the transition point. We demonstrate the working of our method on a 16^4 lattice. We obtain an equidistribution of configurations across the phase transition even for such a relatively large lattice size.Comment: 11 pages, latex, 2 figures included, uuencode

    Enabling Incrementality in the Implicit Hitting Set Approach to MaxSAT Under Changing Weights

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    Recent advances in solvers for the Boolean satisfiability (SAT) based optimization paradigm of maximum satisfiability (MaxSAT) have turned MaxSAT into a viable approach to finding provably optimal solutions for various types of hard optimization problems. In various types of real-world problem settings, a sequence of related optimization problems need to solved. This calls for studying ways of enabling incremental computations in MaxSAT, with the hope of speeding up the overall computation times. However, current state-of-the-art MaxSAT solvers offer no or limited forms of incrementality. In this work, we study ways of enabling incremental computations in the context of the implicit hitting set (IHS) approach to MaxSAT solving, as both one of the key MaxSAT solving approaches today and a relatively well-suited candidate for extending to incremental computations. In particular, motivated by several recent applications of MaxSAT in the context of interpretability in machine learning calling for this type of incrementality, we focus on enabling incrementality in IHS under changes to the objective function coefficients (i.e., to the weights of soft clauses). To this end, we explain to what extent different search techniques applied in IHS-based MaxSAT solving can and cannot be adapted to this incremental setting. As practical result, we develop an incremental version of an IHS MaxSAT solver, and show it provides significant runtime improvements in recent application settings which can benefit from incrementality but in which MaxSAT solvers have so-far been applied only non-incrementally, i.e., by calling a MaxSAT solver from scratch after each change to the problem instance at hand

    Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation.

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    Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] and inositol 1,4-bisphosphate [Ins(1,4)P2]. Specific binding of [125I]IGF-I to isolated membranes from cultured cardiac myocytes amounted to 1-1.2%. Binding of [125I]IGF-I was inhibited by unlabeled IGF-I at nanomolar concentrations and insulin at much higher concentrations. These data suggest that IGF-I binds to its own receptor on rat cardiac myocytes. Competitive binding studies using isolated membranes from cardiac myocytes and [125I]IGF-II showed 2-4% specific binding. Binding of [125I]IGF-II was inhibited by IGF-II and much less potently by IGF-I and insulin. Immunoglobulin G (IgG) 3637 (an IgG directed against the IGF-II/Man6P receptor) partially inhibited binding of [125I]IGF-II whereas nonimmune IgG did not. Affinity cross-linking studies with [125I]IGF-II and cardiac myocyte membranes and subsequent analysis of the ligand-receptor complex using SDS-PAGE and autoradiography showed a radiolabeled band of approximately 250 kilodalton (kDa). The formation of the [125I]IGF-II-receptor complex was inhibited by incubation with IGF-II and IgG 3637 but not by insulin or nonimmune IgG. Western blotting of protein extracts from cultured cardiac myocytes was performed using IgG 3637 and an immunoperoxidase technique for the visualization of the IGF-II/Man6P receptor protein. A specific band at 220 kDa under nonreducing conditions was detected on the blots, providing further evidence for the expression of the IGF-II/Man6P receptor by cardiac myocytes. The effect of IGFs on the accumulation of inositol phosphates was measured by HPLC analysis of perchloric acid extracts from myo-[3H]inositol-labeled cultured cardiac myocytes. IGF-I (50 ng/ml) stimulated the accumulation both of Ins(1,4,5)P3 and Ins(1,4)P2 after 30 sec by 43% and 63%. IGF-II (up to 500 ng/ml) had no significant effect on inositol phosphate accumulation under the same conditions. However, in the presence of millimolar concentrations of Man6P, IGF-II (500 ng/ml) also increased Ins(1,4,5)P3 accumulation by 59%. We conclude that cardiac myocytes from adult rats express IGF receptors and respond to IGFs with the accumulation of Ins(1,4,5)P3 and Ins(1,4)P2. This effect seems to be mediated by an IGF-I receptor-specific pathway

    A phantom for the quantitative determination and improvement of the spatial resolution in slice-selective 2D-FT magnetic resonance micro-imaging and -microscopy based on Deep X-ray Lithography (DXRL)

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    Introduction: The most important assessed quality-control (QC) criteria for improvements in high-resolution imaging are represented by the contrast-to-noise-ratio and spatial resolution. Ultra-High-Field (UHF) Magnetic-Resonance-scanners (B ≥ 7 T) for medical research allowed for the improvement in spatial resolution up to the microimaging and nominal microscopy range [pixel-size: ps < (100 μm)2], even in-vivo on humans just recently. Preclinical MRI- and dedicated MR-microscopy (MRM) scanners already allow for microimaging and MRM (1-256 μm) but lack a sensible spatial resolution phantom for QC and performance improvements in hardware, pulse-sequencing and MRprotocols. In most scientific MRI articles, the spatial resolution is characterized by the ps, though this measurement parameter only limits the actual resolution. Methods: Here the Modulation-Transfer-Function (MTF) is used as evaluation concept for the determination of the spatial resolution in MRM using simple intensity profiles. The resolution limit is defined using a critical modulation-level. In approaching visual impressions on spatial resolution an additional criterion derived from the Modulation-depth-to-Noise-Ratio (MNR) is proposed. A practical method for assessment based on a concrete phantom design and its realization is shown. Results: The phantom design consists of several sets of fine grids, specifically featuring high structural anisotropy for optimum SNR and CNR, with different spatial periods ranging from a1 = 256 μm down to a8 = 2 μm, not only for a quick visual qualitative check, but also for quantification of resolution using the MTF for two different spatial encodings in two orthogonal in-plane directions. The challenging demands on the manufacturing technology especially with regard to the aspect-ratio are approached using Deep-X-Ray-Lithography (DXRL) relying on the high brilliance of Synchroton-radiation. Smallest grid plates with width of 4 μm corresponding to 125 line pairs/mm at a plate depth of 100 μm were achieved. Discussion: MR-microscopic images, originating from a microscopy insert on a human UHF-MR-scanner, were used for demonstration of the evaluation process with two independent resolution-criteria. The developed prototype offers unique possibilities for quantitative resolution QC on UHF human and preclinical MR-scanners. Such a resolution-phantom might be very important for the improvement of MR-pulse-sequences, MR-protocols and even hardware. In principle the phantom can also be used for other microscopic imaging-modalities as for instance μCT and Optical-Coherence-Tomography (OCT)

    A comparative volatility analysis and an enquiry into the future of Bitcoin

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    Master's thesis in Industrial EconomicsThe main object of this thesis is to investigate if Bitcoin has matured as a financial asset. We intend to do this by comparing the volatility of Bitcoin to the volatility of gold and S&P500 using the best fitting GARCH models. By doing this we can examine whether the volatility is decreasing, suggesting a maturing market. We will also look at the correlation between these assets. As part of this thesis we will provide a clear picture of what Bitcoin is, and how it functions. We are also going to uncover some of the opportunities and limitations that faces Bitcoin. This will be done by giving a thorough explanation of the technical aspects of Bitcoin to get a clear image of the security and reliability of Bitcoin and the blockchain-technology. To answer the questions presented in this thesis we used a variety of GARCH models to model the volatility of Bitcoin and other assets. This revealed that Bitcoin exhibits an extreme volatility, which does not seem to be decreasing or stabilizing. This lead to the conclusion that Bitcoin is not yet maturing as a financial asset.submittedVersio

    Does quantized charge transport in disordered Floquet topological insulators require Anderson localization?

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    We perform a numerical study of Floquet topological insulators with temporal disorder to investigate the existence of quantized charge transport without Anderson localization. We first argue that in setups with temporal imperfections Anderson localization can not be expected but bulk transport is diffusive in the long-time limit. In a second step we compute the corrections to the cumulative averaged pumped charge due to the temporal disorder and show that transport is characterized by two regimes: the transient regime, represented by a plateau for uncorrelated disorder, and the long-time behavior with a common scaling law for both uncorrelated and correlated disorder. Most notably, our numerical results indicate that the dynamic corrections vanish in the long-time limit such that quantized charge transport and diffusive bulk motion can coexist in temporally disordered Floquet topological insulators.Comment: 8 pages, 7 figure

    Investigating communication networks contextually: Qualitative network analysis as cross-media research

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    This article introduces the approach of contextualised communication network analysis as a qualitative procedure for researching communicative relationships realised through the media. It combines qualitative interviews on media appropriation, egocentric network maps, and media diaries. Through the triangulation of these methods of data collection, it is possible to gain a differentiated insight into the specific meanings, structures and processes of communication networks across a variety of media. The approach is illustrated using a recent study dealing with the mediatisation of community building among young people. In this context, the qualitative communication network analysis has been applied to distinguish “localists” from “centrists”, “multilocalists”, and “pluralists”. These different “horizons of mediatised communitisation” are connected to distinct communication networks. Since this involves today a variety of different media, the contextual analysis of communication networks necessarily has to imply a cross-media perspective

    Incremental Maximum Satisfiability

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