17 research outputs found
Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry
- Author
- A. L. R. Ng
- Abardia Oliva F. J.
- Abdel Malak S.
- Abdel Wahab H.
- Abdul Kareem B. B.
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- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2015
- Field of study
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis Véronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
- Berks Michael
- Bethel Graeme
- Beugelsdijk Tony J.
- Bhakta Rita
- Bhuchar Venita
- Bi Shihua
- Bian Xuemeng
- Bieri Tamberlyn
- Bimage Kesha E.
- Bird Christine
- Birditt Brian
- Birney Ewan
- Birney Ewan
- Birren Bruce
- Bissell Helen
- Biswalo Kaneza
- Bituin Aleksandr
- Black Stacey
- Blackburne-Maze Suzanne
- Blair Jessica Anne
- Blakey Sarah
- Blanks Tia
- Blasiar Darin
- Blazej Robert
- Blitshsteyn Berta
- Blomstrom David B.
- Bloom Scott
- Bloom Toby
- Blumer Heather
- Blye Jason
- Blyth Peter R.
- Blöcker Helmut
- Boatright Elizabeth
- Boehm John
- Boen Juanan
- Boguslavskiy Leonid
- Bolton Christel
- Bolund Lars
- Bondoc Marnel
- Bonfield James
- Bonnett Ralph
- Bonnin David
- Border Richard
- Borowsky Mark
- Borzym Katja
- Boukhgalter Boris
- Bowen Eric
- Bradley Amanda
- Bradshaw-Cordum Holly
- Brady Nicola
- Brandriff Brigitte F.
- Brannon Wade
- Branscomb Elbert
- Bray Jason
- Bray-Allen Sarah
- Brettin Thomas
- Bridgeman Anne
- Bridgers Michael
- Brimhall Angela K.
- Brokstein Peter
- Brook Jonathan
- Brooking Shane
- Brottier Philippe
- Brown Andrew
- Brown Clive
- Brown Jacqui
- Brown Margaret
- Brown Mary
- Brown Mary J.
- Brown Michael
- Brown Nancy C.
- Bruce David D.
- Bruce Robert
- Bruno William J.
- Bruskiewich Richard
- Bryant Jackie
- Bryant Jennifer E.
- Bryant Nathaniel P.
- Brüls Thomas
- Buatsi Delali
- Buck David
- Buckingham Judith M.
- Buckle Veronica
- Buczek Donald
- Budd Claire
- Buhay Christian J.
- Bulbul Kerem
- Buller Sarah
- Bunker Nathan
- Burberry Jill
- Burch Paula Ellen
- Burford Deborah
- Burgess Joanne
- Burgin Matt
- Burkett Carrie E.
- Burkhart-Schultz Karolyn
- Burrell Kevin L.
- Burrill Wayne
- Burrows Christine
- Burton Christine
- Burton John
- Butcher Phil
- Butler Adam
- Butler Jon
- Butler Paul
- Caenepeel Sean
- Cahill Patrick
- Cai Tianjing
- Cai Zhen
- Cairns Murray
- Calderon Eliana
- Callen David F.
- Camarata Jody
- Camire David
- Camm Nick
- Campbell Christopher
- Campbell Connie S.
- Campbell Evelyn W.
- Campbell Mary I.
- Campbell Mary L.
- Campo Kevin
- Canning Bruno
- Cao Ting
- Cao Yuzhu
- Caoile Chenier
- Cardenas Faviola
- Cardenas Lolo
- Cardenas Veronica
- Carder Carol
- Carder Paul
- Carpenter Kelly
- Carrano Anthony V.
- Carriere Jason
- Carter Jason
- Carter Kelvin
- Carter Nigel
- Caruso Lauren
- Casias Kristal
- Cattolico Laurence
- Cavanna Tamara
- Cavazos Iracema
- Cavazos Sandra R.
- Ceasar Heather
- Cedroni Maria
- Cepeda Mario
- Chacko Joseph
- Chain Patrick
- Chalk Shani
- Challacombe Jean F.
- Chan Ka
- Chan Sheryl N.
- Chan Yee Man
- Chang Jean L.
- Chapman Jarrod
- Chapman Joanna
- Chapple Jeffrey
- Charles Rachel
- Chasteen Leslie A.
- Chavarria Simeon
- Chazaro Bruno
- Chen Baoxian
- Chen Bin
- Chen Chira
- Chen Chong
- Chen Chong
- Chen Chun-Nan
- Chen Cong
- Chen Ellson
- Chen Hsiu-Chuan
- Chen Jianlong
- Chen Jie
- Chen Jin
- Chen Junbao
- Chen Lihong
- Chen Lixia
- Chen Ray
- Chen Shu
- Chen Tong
- Chen Xiaoyun
- Chen Xinyi
- Chen Yanjiong
- Chen Yiyu
- Chen Zhu
- Chen Zhu
- Chen Zhu
- Cheng Jan-Fang
- Cheng Zhihua
- Chertkov Olga
- Cheshatsang Yama
- Chi Cheng
- Chi Han C.
- Chillingworth Neil
- Chin Sylvia
- Chinn Corey
- Chinwalla Asif
- Chissoe Stephanie
- Chiu Sally
- Chothia Tom
- Christensen Mari
- Christopoulos Constantine
- Chu Joseph
- Chui Connie
- Chung A
- Cinkowsky Michael J.
- Citroen Mieke
- Clack Rob
- Clamp Michele
- Clark Anthea
- Clark Graham
- Clark Kevin
- Clark Lynn
- Clark Lynn M.
- Clark Richard
- Clark Sarah
- Clark Sue
- Clarke Adrian
- Clarke Betty
- Clarke Eddie
- Clarke Kay
- Clarke Laura
- Clawson Hiram
- Clee Chris
- Clegg Shelia
- Clerc Blankenburg Kerstin Petra
- Cleveland David
- Clifford Karen
- Clifton Sandra W.
- Coates Julia
- Cobley Victoria
- Cockrell Raynard
- Coffey Alison
- Cofield Jackie
- Coggill Penelope
- Cohn Judith D.
- Colayco Rick
- Cole Lotte
- Collier Rachael
- Collings Simon
- Collins Francis S.
- Collins John
- Collins Philip
- Collymore Al
- Colman Louise
- Combs Jessie
- Comstock Robin
- Cong Bin
- Conner Richard
- Connolly Anthony
- Connolly Karen
- Conquer Jennie
- Conrad Ansgar
- Conroy Donald
- Considine Tony
- Constance Doug
- Cook April
- Cook Leanna
- Cooke Patrick
- Cooper Jonathan
- Cooper Rachel
- Cooper Robert
- Copeland Alex
- Coppola Maria
- Copsey Teresa
- Corby Nicole
- Cordes Matt
- Cordray Rebecca
- Cornell Christine
- Cornell Earl
- Cornell Linda
- Cornell Ruth
- Corum Ben
- Cottage Amanda
- Cotton Sara
- Coulson Alan
- Couronne Olivier
- Courtney Laura P.
- Coville Gez
- Cox Anthony
- Cox Caroline D.
- Cox Tony
- Coxhill Robert
- Coyle Marcus D.
- Craig Matthew
- Crane Tom
- Crawford Amanda L.
- Crawley Matt
- Cree Andrew
- Crespeau Hervé
- Crew Victor
- Critchlow Terrance
- Critz Paul
- Cruaud Corinne
- Cuff James
- Cui Hongjuan
- Cui Jinhui
- Cui Peng
- Cui Peng
- Culley Karl
- Cummings Auli
- Cummings Kirsti
- Cummings Paul
- Cummings Stephanie
- Cuomo Christina A.
- Curran Adam
- Curwen Valery
- Cutts Jeffrey
- Czubayko Martin
- D\u27Souza Lisa Marie
- Da Silva Corinne
- Dai Li
- Dalin Eillen
- Dang Michelle
- Danganan Linda
- Daniels Rachael
- Dathorne Stephanie R.
- Daum Christopher
- David Robert
- Davidson Lucy
- Davidson Stuart
- Davies Jonathon
- Davies Joy
- Davies Nicholas
- Davies Robert
- Davila Mary Louise
- Davis Candi Mon\u27et
- Davis Cheryl
- Davis Clay
- Davis Jayne
- Davis John
- Davis Matthew
- Davy-Carroll Latarsha
- Dawoe Tenzin
- Dawson Elisabeth
- De Anda Claudia
- De Latorre Andrea
- Deadman Rebecca
- Dean Peter
- Dear Simon
- Dearden Frances
- DeArellano Kurt
- Deaven Larry I.
- Deaven Larry L.
- Deere Kerry
- DeGray Stewart
- Degusta David
- Deguzman Maria
- Dehal Paramvir
- Delgado Marcos
- Delgado Oliver
- Delhaunty Kimberley
- Deloukas Panos
- Deng Yajun
- Dennis Janet
- Denson Shawn
- Denys Mirian
- Deramo Christine
- Desai Anu
- Detter John C.
- Devlin Laurie
- Dewar Ken
- Dhami Pawandeep
- Dhongsar Chemey
- Dias Jennifer
- Dias Victoria
- Dibartolo Genevieve
- Dibling Catherine
- Dickson Mark
- Diekhans Mark
- Dietz-Band Jeanne
- Digennaro Richard
- Dilts Karen
- Dimitrijevic-Bussod Mira
- Ding Hao
- Ding Keyue
- Ding Li
- Ding Yan
- Dinh Huyen H.
- Dixon Kami
- Do Long
- Dobbs Ruth
- Dobson Richard
- Dockree Catherine
- Doddington Daniel
- Dodsworth Steven
- Doggett Norman
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- Dong Hui
- Dong Kimberly
- Dong Wei
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- Dong Xiaojia
- Donlin Jeremy E.
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- Dooling David
- Dorje Passang
- Dorjee Kunsang
- Dorris Lester
- Dorsett Victor
- Doucette-Stamm Lynn
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- Draper Heather
- Du Feiyu
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- Dubchak Inna
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- Dunwell Erin
- Dupes Alan
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- Dutta Ireena
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- Eckenberg Ralph
- Edgar Darren
- Edionwe Susan Omwanghe Osayanro
- Edwards Carol
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- Edwards Karen
- Egan Amy
- Eichler Evan
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- Ejima Fumio
- Elkin Chris
- Ellington Andrew
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- Elliot Jeffrey
- Ellwood Matthew
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- Emelianenko Natalia
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- Erickson Jeffery
- Erler Anne Marie
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- Evans Gareth
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- Eveleth Gerald
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- Faro Susan
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- Fawcett Joseph J.
- Fechtel Kim
- Fellingham Charlotte
- Felming Claire
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- Fernando Pushpa Ranjani
- Ferriera Pat
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- Fonknechten Núrua
- Footman Simon
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- Fu Gang
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- Fujiyama Asao
- Fukawa Rintaro
- Fuller Liam
- Fuller Sharin
- Fullerton Kathryn
- Fulton Lucinda A.
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- Furey Terrence S.
- Furuhashi Mie
- Förste Silke
- Gabisi Abdul M.
- Gage Diane
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- Garcia Carmen
- Garcia Emilio
- Garcia Marvin
- Garcia Ricardo M, III
- Garcia-Martinez Antonio
- Gardner Alison
- Gardner Alison
- Garduno Consuelo
- Gardyna Steph
- Garner Patrick
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- Garnett Jane
- Garza Melissa
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- Gatland Leigh
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- Georgescu Anca
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- Gibbs Ben
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- Gong Guanghui
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- Goodstadt Leo
- Goodstein David
- Goodwin Lynne A.
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- Graham Joe
- Grandbois Edward
- Grant Jennifer
- Grant Michael
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- Graves Tina A.
- Gray Bruce
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- Green Lisa
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- Gregory Simon
- Grewal Nennu
- Gribble Susan
- Griffith Jeffrey K.
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- Griffiths Ed
- Griffiths Mark
- Griffiths-Jones Sam
- Grigoriev Igor
- Grimwood Jane
- Grocock Russell
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- Gu Jingli
- Gu Jun
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- Gu Wenyi
- Gu Wenyi
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- Guan Qiaoning
- Guarin Hannibal
- Guel Metzalli
- Guerra William
- Guevara Whitney V.
- Gui Qi
- Gunaratne Preethi
- Gunning Kate
- Guo Daorong
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- Gustafson Erik
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- Ha Chi
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- Hajek Patrick
- Hall Brett Lynn
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- Hamada Junko
- Hamilton Cerissa
- Hamilton Keelan A.
- Hamilton Matt
- Hamlett John
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- Hamza Khalid
- Han Guiqing
- Han Shunsheng
- Han Xurong
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- Hancock Julie
- Harbes Brandy A.
- Harding Adam
- Harkins C. Richard
- Harley Joanne
- Harper David
- Harper Georgina
- Harper Patrik
- Harradence Grant
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- Hasegawa Tomoko
- Hashimoto Etsuko
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- Hassan Daniel
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- Haugen Eric
- Haussler David
- Havlak Paul
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- Hawkins Ebere Sylvia Onyirioha
- Hawkins Natalie
- Hawkins Trevor
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- Haydu Lauren
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- Heinze Ivonne
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- Herseim Allyson
- Hewitt Stephen
- Heyen Joshua
- Higgs Douglas
- Hildebrand Carl E.
- Hillier LaDeana
- Hillyard Guy
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- Hinrichs Angela S.
- Hitchens Matthew Edward
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- Holden Jane
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- Hood Leroy
- Hooper Alison
- Hopewell Lucy
- Hopkins Ben
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- Hosoda Kei
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- Hosseini Roya
- Hou Shunfang
- Hou Xiaodi
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- Howard Philip
- Howard Stephanie R.
- Howden Philip
- Howe Kevin
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- Howell Latoya Lynette
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- Hsu Fan
- Hu George
- Hu Jie
- Hu Songnian
- Huang Fang
- Huang Guyang
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- Huang Mei
- Huang Wayne
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- Huang Zhengping
- Hubbard Timothy
- Huber James W.
- Huckle Elizabeth
- Hue Heather
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- Hupman Matt
- Huynh Sandy
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- Imbro Paula
- Imo Kelvin C.
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- Ishizaki Hinako
- Isozaki Emi
- Israni Sanjay
- Ito Fumiaki
- Ito Noriko
- Itoh Takehiko
- Iwakawa Shinobu
- Iwatate Mariko
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- Iyer Vivek
- Izatt Janet
- Izmajlowicz Monica
- Izumiyama Tomohiro
- Jacintho Mark
- Jackson Laronda R.
- Jackson Terri
- Jacob Leni Susan
- Jaeger Sara
- Jaffe David B.
- Jahn Niels
- Jaklevic Joseph
- Jaklevic Michael
- James Kent W.
- Jareborg Niclas
- Jarek Michael
- Jassal Bijay
- Jeffery Grant
- Jeffery Kim
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- Jekosch Kerstin
- Jenkins Lee
- Jett Jamie
- Jewett Phillip E.
- Jia Jia
- Jia Jia
- Jia Nan
- Jia Xingchang
- Jiang Lu
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- Jiang Ziyou
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- Jin Jian
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- Jones Micheil
- Jones Myrna D.
- Jones Steven
- Jong Pieter De
- Jordan Yun
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- Kato Takako
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- Keenan Stephen
- Kegelmeyer Laura
- Kegg Lisa
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- Kelly Susan H.
- Kershaw Joanna
- Kettleborough Ross
- Keys David
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- Khurama Divya
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- Kohlberg Sara
- Kojima Kazuyasu
- Kolbe William
- Kong Yi
- Korf Ian
- Kosiura Anna
- Kou Zhaohui
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- Krawczyk Marie-Claude
- Kremitzki Colin
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- Krogh Anders
- Kronmiller Brent
- Kruchowski Scott S.
- Kube Michael
- Kubischta Duane
- Kudoh Jun
- Kuehl Jennifer
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- Kulish Larissa
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- Kwan Chinnie
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- Lai Jianghua
- Lai Teresa
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- Laing Michael
- Laird Gavin
- Lam Edward
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- Lamar Betty
- Lambart Christine
- Lamble Ralph
- Lamerdin Jane E.
- Lander Eric S.
- Landers Tom
- Langford Cordelia
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- Lapidus Alla
- Larke Ben
- Lato Bernadette
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- Lei Meng
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- Lindo Ken
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- Liu Yu
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- Lui Annie
- Lundgren Lyndsey
- Luo Chunqing
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- Mullenger Ian
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- Muzny Donna Marie
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- Nguyen Natalie M.
- Nguyen Ngoc Bich
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- Nickerson Tim
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- Ning Zemin
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- Noguchi Hideki
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- Norbu Nyima
- Nordsiek Gabriele
- Norris Sarah Louise
- Novik Karen
- Nowlin Larry
- Nusbaum Chad
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- Nwokenkwo Stanley
- O\u27Donnell Paula
- O\u27Donovan Daniel
- O\u27Leary Sinead
- O\u27Loughlin Jennifer
- O\u27Neill Keith
- Obayashi Izumi
- Obregon Melissa
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- Ohno Saho
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- Omotosho Bamidele
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- Yao Zhijian
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- Ye Chen
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- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
La comercializacion de la industria del aserrio en la VII Region
- Author
- Publication venue
- Universidad de Talca (Chile). Escuela Contador Publico y Auditor
- Publication date
- Field of study
104 p
Structural and vibrational properties of the ordered Y2CaGe 4O12 germanate: A periodic ab initio study
- Author
- Adamo C.
- Alexander P. Tyutyunnik
- Anatoliy E. Nikiforov
- Baran E. J.
- Baran E. J.
- Becke A. D.
- Becke A. D.
- Becke A. D.
- Belokoneva E. L.
- Bender J. P.
- Bilc D. I.
- Caldiño U.
- Canepa P.
- Cascales C.
- Catti M.
- Civalleri B.
- Corno M.
- Corà F.
- Corà F.
- Dai P. L.
- Dammak T.
- De La Pierre M.
- Demichelis R.
- Demichelis R.
- Demichelis R.
- Demichelis R.
- Ding J.
- Dirac P. A. M.
- Dovesi R.
- Emma G. Vovkotrub
- Ernzerhof M.
- Fateley W. G.
- Foumakoye G.
- Frisch M. J.
- Gabelica-Robert M.
- Gaewdang T.
- Galuskin E. V.
- Gao G. J.
- Guo P. M.
- Hammink T. S.
- Hanuza J.
- Haoudi-Mazzah A.
- Hohenberg P.
- Ivan I. Leonidov
- Janesko B. G.
- Jaque D.
- Juarez-Arellano E. A.
- Kaindl R.
- Kaminskii A. A.
- Kohn W.
- Larson A. C.
- Lavat A. E.
- Lazarev A. N.
- Lee C. T.
- Leonidov I. I.
- Lewis J. S.
- Li W. Y.
- Li Y. C.
- Lipina O. A.
- Liu B.
- Melkozerova M. A.
- Meyer A.
- Monkhorst H. J.
- Mączka M.
- Noël Y.
- Noël Y.
- Pascale F.
- Perdew J. P.
- Perdew J. P.
- Perdew J. P.
- Perdew J. P.
- Pisarev R. V.
- Popov S. E.
- Prencipe M.
- Prencipe M.
- Ramos-Lara F.
- Romero J. J.
- Roothaan C. C. J.
- Rousseau D. L.
- Rude L. H.
- Ruiz E.
- Saez-Puche R.
- Sarkisov S. E.
- Searle B. G.
- Slater J. C.
- Staroverov V. N.
- Steger E.
- Steger E.
- Stephens P. J.
- Tarakina N. V.
- Tarte P.
- Toby B. H.
- Tomaszewski P. E.
- Többens D. M.
- Ugliengo P.
- Uhlich D.
- Vladimir A. Chernyshev
- Vladimir G. Zubkov
- Vladislav P. Petrov
- Vosko S. H.
- Wells J. P. R.
- Wells J. P. R.
- Wierzbicka-Wieczorek M.
- Wu A. H.
- Wu A. H.
- Wu Z.
- Yang H. M.
- Yang H. M.
- Yoon K. H.
- Zhang J. C.
- Zhao F.
- Zhuravlev V. D.
- Zicovich-Wilson C. M.
- Zubkov V. G.
- Zubkov V. G.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- 01/01/2014
- Field of study
DFT calculations with six LDA, GGA, and hybrid functionals have been performed using the CRYSTAL09 code to describe the crystal structure and vibrational spectra of Y2CaGe4O12 cyclotetragermanate, a new optical host. Two space groups P4/nbm and Cmme have been considered. The former corresponds to a mixed (0.5 Ca + 0.5 Y) distribution at the octahedral sites found from the results of Rietveld refinement of room temperature powder XRD pattern; the latter refers to the model of crystallographically nonequivalent calcium and yttrium atomic setting in distorted oxygen octahedrons. The most accurate geometry description has been obtained with the WC1LYP and PBE (n = 6) hybrid functionals, while the B3LYP calculation provides the best agreement between the recorded infrared and Raman spectra and their computed counterparts. Assignments of most of the observed bands to vibrational modes are given. The comparison between calculated and experimental frequencies shows a general good agreement for the spectra below 600 cm-1. The relationship between selected infrared bands and Raman lines, internal vibrations of the [Ge4O12] unit, and external modes is briefly discussed. © 2014 American Chemical Society
Structural and Vibrational Properties of the Ordered Y 2
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- Adamo C.
- Alexander P. Tyutyunnik
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- Zubkov V. G.
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- 'American Chemical Society (ACS)'
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- Field of study
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study
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- Aboshady Abdelrhman
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- Tilouch N.
- Timenetsky Karina Tavares
- Tirapu Juna
- Todeschini M.
- Tomas Roser
- Tomaszewski C.
- Tomescu D. Rodica
- Tonetti T.
- Tonnelier A.
- Trinder John T.
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- Weller D.
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- Williams E.
- Williams K.
- Wilson Antoinette
- Wojtas Jadwiga
- Won Huh J.
- Wrathall David Wayne
- Wright Christopher
- Wu J.-F.
- Wunsch H.
- Xi Guo
- Xing Zhengjiang
- Xu H.
- Yamamoto K.
- Yan Jie
- Yang X.
- Yates E.
- Yazicioglu Mocin Özlem
- Ye Zhenglong
- Yildirim F.
- Yoshida Norifumi
- Yoshido Hector Higo Leon
- Young Lee B.
- Yu Gong
- Yu R.
- Yu T.
- Yuan B.
- Yuangtrakul N.
- Yumoto Tetsuya
- Yun Xie
- Yáñez J.
- Zakalik G.
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zambon Massimo
- Zang Bin
- Zani G.
- Zarka Jonathan
- Zeggwagh A.A.
- Zerbi S.M.
- Zerman A.
- Zetterquist H.
- Zhang Guoxiu
- Zhang Hongwen
- Zhang Jiuzhi
- Zhang W.
- Zhang Weixin
- Zhao H.
- Zheng Jia
- Zhu Bin
- Zumaran R.
- Çukurova Z.
- Öveges Nándo
- Publication venue
- Elsevier
- Publication date
- 01/01/2023
- Field of study
International audienceBackground: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society
Search for intermediate-mass black hole binaries in the third observing run of Advanced LIGO and Advanced Virgo
- Author
- Abbott Rich
- Abbott Thomas D.
- Acernese Fausto
- Ackley Kendall
- Adams Carl
- Adhikari Naresh
- Adhikari Rana X.
- Adya Vaishali B.
- Affeldt Christoph
- Agarwal Deepali
- Agathos Michalis
- Agatsuma Kazuhiro
- Aggarwal Nancy
- Aguiar Odylio D.
- Aiello Lorenzo
- Ain Anirban
- Ajith P.
- Akutsu Tomotada
- Albanesi Simone
- Allocca Annalisa
- Altin Paul A.
- Amato Alex
- Anand Chandana
- Anand Shreya
- Ananyeva Alena
- Anderson Stuart B.
- Anderson Warren G.
- Ando Masaki
- Andrade Tomas
- Andres Nicolas
- Andrić Tomislav
- Angelova Svetoslava V.
- Ansoldi Stefano
- Antelis J.M.
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- Appert Stephen
- Arai Koji
- Arai Koya
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- Weiss Rainer
- Weller Colin M.
- Weller R.
- Wellmann Felix
- Wen Linqing
- Wette Karl
- Weßels Peter
- Whelan John T.
- White Derek D.
- Whiting Bernard F.
- Whittle Chris
- Wilken Dennis
- Williams Daniel
- Williams Michael J.
- Williamson Andrew R.
- Willis Joshua L.
- Willke Benno
- Wilson Dalziel J.
- Winkler Walter
- Wipf Christopher C.
- Wlodarczyk Tom
- Woan Graham
- Woehler Janis
- Wofford Jared K.
- Wong I.C. F.
- Wu C.
- Wu David S.
- Wu H.
- Wu S.
- Wysocki Daniel M.
- Xiao Liting
- Xu W-R.
- Yamada Tomohiro
- Yamamoto Hiro
- Yamamoto Kazuhiro
- Yamamoto Kohei
- Yamamoto Takahiro
- Yamashita Kanta
- Yamazaki Ryo
- Yang Fengwei W.
- Yang Le
- Yang Yang
- Yang Yi
- Yang Ziyan
- Yap M.J.
- Yeeles David W.
- Yelikar Anjali B.
- Ying Make
- Yokogawa Kazuya
- Yokoyama J.
- Yokozawa Takaaki
- Yoo Jooheon
- Yoshioka Toshiya
- Yu Hang
- Yu Haocun
- Yuzurihara Hirotaka
- Zadrożny Adam
- Zanolin Michele
- Zeidler Simon
- Zelenova Tatiana
- Zendri J.-P.
- Zevin Michael
- Zhan Mingsheng
- Zhang Hong
- Zhang Jue
- Zhang Liyuan
- Zhang Teng
- Zhang Yanqi
- Zhao Chunnong
- Zhao Guoying
- Zhao Yue
- Zhao Yuhang
- Zhou Ruinan
- Zhou Zifan
- Zhu Xingjiang J.
- Zhu Z.-H.
- Zimmerman Aaron B.
- Zlochower Y.
- Zucker Michael E.
- Zweizig John
- Publication venue
- 'EDP Sciences'
- Publication date
- 01/01/2022
- Field of study
International audienceIntermediate-mass black holes (IMBHs) span the approximate mass range 100−105 M⊙, between black holes (BHs) that formed by stellar collapse and the supermassive BHs at the centers of galaxies. Mergers of IMBH binaries are the most energetic gravitational-wave sources accessible by the terrestrial detector network. Searches of the first two observing runs of Advanced LIGO and Advanced Virgo did not yield any significant IMBH binary signals. In the third observing run (O3), the increased network sensitivity enabled the detection of GW190521, a signal consistent with a binary merger of mass ∼150 M⊙ providing direct evidence of IMBH formation. Here, we report on a dedicated search of O3 data for further IMBH binary mergers, combining both modeled (matched filter) and model-independent search methods. We find some marginal candidates, but none are sufficiently significant to indicate detection of further IMBH mergers. We quantify the sensitivity of the individual search methods and of the combined search using a suite of IMBH binary signals obtained via numerical relativity, including the effects of spins misaligned with the binary orbital axis, and present the resulting upper limits on astrophysical merger rates. Our most stringent limit is for equal mass and aligned spin BH binary of total mass 200 M⊙ and effective aligned spin 0.8 at 0.056 Gpc−3 yr−1 (90% confidence), a factor of 3.5 more constraining than previous LIGO-Virgo limits. We also update the estimated rate of mergers similar to GW190521 to 0.08 Gpc−3 yr−1.Key words: gravitational waves / stars: black holes / black hole physicsCorresponding author: W. Del Pozzo, e-mail: [email protected]† Deceased, August 2020
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study
- Author
- Abe Toshikazu
- Aboshady Abdelrhman
- Abrough Fekri
- Acampo-de Jong Melanie
- Acharya Subhash
- Acharya Subhash P
- Adderley Jane
- Adiguzel Nalan
- Agrawal Vijay Kumar
- Aguilar Gerardo
- Aguirre Gaston
- Aguirre-Bermeo Hernan
- Ahlström Björn
- Akbas Türkay
- Akker Mustafa
- Al Sadeh Ghamdan
- Alamri Sultan
- Algaba Angela
- Ali Muneeb
- Aliberti Anna
- Allegue Jose Manuel
- Alvarez Diana
- Amador Joaquin
- Amin Pravin
- Andersen Finn H
- Ansari Sharique
- Apichatbutr Yutthana
- Apostolopoulou Olympia
- Arabi Yaseen
- Arabi Yaseen
- Aragao Irene
- Aragao Irene
- Arellano Daniel
- Arica Mestanza
- Arikan Huseyin
- Arinaga Koichi
- Arnal Jean-Michel
- Asano Kengo
- Asín-Corrochano Marta
- Avalos Cabrera Jesus Milagrito
- Avila Fuentes Silvia
- Aydemir Semih
- Aygencel Gulbin
- Azevedo Luciano
- Bacakoglu Feza
- Badie Julio
- Baedorf Kassis Elias
- Bai Gabriela
- Balaraj Govindan
- Ballico Bruno
- Banner-Goodspeed Valerie
- Banwarie Preveen
- Barbieri Rosella
- Baronia Arvind
- Barrett Jonathan
- Barrot Loïc
- Barrueco-Francioni Jesus Emilio
- Barry Jeffrey
- Bauer Philippe
- Bauer Philippe
- Bawangade Harshal
- Beavis Sarah
- Beck Eduardo
- Beduneau Gaëtan
- Beduneau Gaëtan
- Beehre Nina
- Beitler Jeremy
- Belenguer Muncharaz Alberto
- Bellani Giacomo
- Bellani Giacomo
- Belliato Mirko
- Bellissima Agrippino
- Beltramelli Rodrigo
- Ben Souissi Asma
- Benitez-Cano Adela
- Benlamin Mohamed
- Benslama Abdellatif
- Bento Luis
- Benvenuti Daniela
- Berkius Johan
- Berkius Johan
- Bernabe Laura
- Bersten Andrew
- Berta Giacomo
- Bertini Pietro
- Bertram-Ralph Elliot
- Besbes Mohamed
- Bettini Lisandro Roberto
- Beuret Pascal
- Bewley Jeremy
- Bezzi Marco
- Bhakhtiani Lakshay
- Bhandary Rakesh
- Bhowmick Kaushik
- Bihari Shailesh
- Bissett Bernie
- Blythe David
- Bocher Simon
- Boedjawan Narain
- Bojanowski Christine M
- Boni Elisa
- Boraso Sabrina
- Borelli Massimo
- Borello Silvina
- Borislavova Margarita
- Bosma Karen J
- Bottiroli Maurizio
- Boyd Owen
- Bozbay Suha
- Briva Arturo
- Brochard Laurent
- Brochard Laurent
- Bruel Cédric
- Bruni Andrea
- Buehner Ulrike
- Bugedo Guillermo
- Bugedo Guillermo
- Bulpa Pierre
- Burt Karen
- Buscot Mathieu
- Buttera Stefania
- Cabrera Jorge
- Caccese Roberta
- Caironi Pietro
- Camporota Luigi
- Canchos Gutierrez Ivan
- Canedo Nancy
- Cani Alma
- Cappellini Iacopo
- Carazo Jesus
- Cardonnet Luis Pablo
- Carpio David
- Carriedo Demetrio
- Carrillo Ramón
- Carvalho João
- Caser Eliana
- Castelli Antonio
- Castillo Quintero Manuel
- Castro Heloisa
- Catorze Nuno
- Cengiz Melike
- Cereijo Enrique
- Cerny Vladimir
- Ceunen Helga
- Chaintoutis Christos
- Chang Youjin
- Chaparro Gustavogcha
- Chapman Carmel
- Chau Simon
- Chavez Cecilia Eugenia
- Chelazzi Cosimo
- Chelly Jonathan
- Chemouni Frank
- Chen Kai
- Chena Ariel
- Chiarandini Paolo
- Chilton Phil
- Chiumello Davide
- Cho Young-Jae
- Cho Young-Jae
- Chou-Lie Yvette
- Chudeau Nicolas
- Cinel Ismail
- Cinnella Gilda
- Clark Michele
- Clark Thomas
- Clarkson Kevin
- Clarkson Kevin
- Clementi Stefano
- Coaguila Luis
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- Wardi Gabriel
- Ween-Velken Nils Christian
- Wei Bi-Lin
- Weller Dolf
- Welsh Deborah
- Welters Ingeborg
- Wert Michael
- Whiteley Simon
- Wilby Elizabeth
- Williams Erin
- Williams Karen
- Wilson Antoinette
- Wojtas Jadwiga
- Won Huh Jin
- Wrathall David
- Wright Christopher
- Wu Jian-Feng
- Wunsch Hannah
- Xi Guo
- Xing Zheng-Jiang
- Xu Hongyang
- Yamamoto Kotaro
- Yan Jie
- Yang Xiaobo
- Yates Elliot
- Yazicioglu Mocin Ozlem
- Ye Zhenglong
- Yildirim Fatma
- Yoshida Norifumi
- Yoshido Hector Higo Leon
- Young Lee Bo
- Yu Gong
- Yu Rongguo
- Yu Tao
- Yuan Boyun
- Yuangtrakul Nadwipa
- Yumoto Tetsuya
- Yun Xie
- Yáñez Julio
- Zakalik Graciela
- Zaki Ahmad
- Zalba-Etayo Begoña
- Zambon Massimo
- Zang Bin
- Zani Gianluca
- Zarka Jonathan
- Zeggwagh Amine Ali
- Zerbi Simone Maria
- Zerman Avsar
- Zetterquist Harald
- Zhang Guoxiu
- Zhang Hongwen
- Zhang Jiuzhi
- Zhang Wei
- Zhang Weixin
- Zhao Hongsheng
- Zheng Jia
- Zhu Bin
- Zumaran Ronald
- Çukurova Zafer
- Öveges Nándo
- Özyilmaz Ezgi
- Publication venue
- 'Elsevier BV'
- Publication date
- 21/01/2023
- Field of study
Background
Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation.
Methods
WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109.
Findings
Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital.
Interpretation
In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study
- Author
- Abdelhamid Hachimi
- Abdellatif Benslama
- Abdelrhman Aboshady
- Abhijit Duggal
- Abidi Khalid
- Abubaker S Elmaryul
- Adela Benitez-Cano
- Adi Hadzibegovic
- Adrian Regli
- Agnes Sarkany
- Agnieszka Kubisz-Pudelko
- Agrippino Bellissima
- Agueda Ojados
- Ahmad Zaki
- Ahmed Rabie
- Aikaterini Dimoula
- Aiman Tulaimat
- Aitor Olmos
- Akihiro Takaba
- Akira Kuriyama
- Akram Khan
- Alastair Rose
- Alberto Belenguer Muncharaz
- Alberto Deicas
- Alberto Facchini
- Aldana Ruiz Robledo
- Alejandro Esquivel
- Alejandro Gonzalez-Castro
- Alejandro Risso Vazquez
- Alejandro Ubeda
- Alessandra Nasi
- Alex Martin
- Alexandre Molin
- Alexandre Tonnelier
- Alexey Gritsan
- Alexey Gritsan
- Alexis Jaspe Codecido
- Alfred Papali
- Alisha Van Axel
- Alistair Nichol
- Alma Cani
- Ameet Parekh
- Amine Ali Zeggwagh
- Amira Jamoussi
- Amy Collins
- Ana Raquel Lima
- Ana Vaz
- Ana Villagra
- Ana Vochin
- Anahita Rouze
- Anaid Manzano
- Analía Garcia
- Anand Thakur
- Anatilde Diaz
- Andrea Bruni
- Andrea Coppadoro
- Andrea Cortegiani
- Andrea Gabriela Peña Padilla
- Andrea Gigante
- Andrea Neville Cracchiolo
- Andrew Bersten
- Andrew Hermon
- Andrew McKown
- Andrew Seely
- Andrew Stapleton
- Andrey Gazenkampf
- Andrey Malyarchikov
- Angela Algaba
- Angela Rogers
- Angelo Giacomucci
- Angus Richardson
- Anil Hormis
- Anna Aliberti
- Anna Mattsson
- Antoinette Wilson
- Antonella Fortunato
- Antonella Frattari
- Antonia Vazquez-Sanchez
- Antonio Castelli
- Antonio Landaverde Lopez
- Antonio Luis Ruiz-Aguilar
- Anxela Vidal
- Aragao Irene
- Arantxa Mas
- Ariel Chena
- Arif Moghal
- Arnaud W Thille
- Aroa Gomez
- Arturo Briva
- Arvind Baronia
- Ary Serpa Neto
- Ary Serpa Neto
- Arzu Esen Tekeli
- Ashish K Khanna
- Ashish Rai
- Asim Shah
- Asisclo Villagomez
- Asisclo Villagomez
- Asma Ben Souissi
- Assem Abdel Razek
- Aude Garnero
- Aurélie Joret
- Avsar Zerman
- Ayca Gumus
- Ayse Nur Soyturk
- Banambar Ray
- Basanta Kumar Pati
- Beatriz Llorente
- Beduneau Gaëtan
- Begoña Zalba-Etayo
- Bellani Giacomo
- Benjamin Delmas
- Bernardo Panka
- Bernardo Panka
- Bernie Bissett
- Bertrand Sauneuf
- Betania Silva Sales
- Betty Tsuei
- Bhagyesh Shah
- Bi-Lin Wei
- Bin Zang
- Bin Zhu
- Björn Ahlström
- Bo Young Lee
- Bojan Jovanovic
- Bojan Jovanovic
- Borja Fernandez
- Boyun Yuan
- Brahim Housni
- Branislava Stefanovic
- Brit Ågot Sjøbø
- Brochard Laurent
- Bror Anders Johnstad
- Bruno Ballico
- Bruno Vilela Costa Pinto
- Candelaria de Haro
- Carla Santos
- Carlo Alberto Volta
- Carlo Oliveri
- Carlos Ferrando
- Carlos Munoz de Cabo
- Carlos Pellegrini
- Carmel Chapman
- Carmen Hernandez
- Caroline Kane
- Catalina Forteza
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- Kotaro Yamamoto
- Kristian Strand
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- Kyeongman Jeon
- Kyung Sook Hong
- Laake Jon Henrik
- Laffey John G
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- Su Hwan Lee
- Subhash Acharya
- Subhash P Acharya
- Sughrat Siddiqui
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- Sundar Raj Ashok
- Sunil Jamadarkhana
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- Susana Temprano
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- Sébastien Perbet
- Taha Pasha
- Tai Pham
- Tai SunPark
- Taiga Itagaki
- Takuya Shiga
- Tamaas Leiner
- Tamasato Tamasato
- Tananchai Petnak
- Tao Yu
- Tapia Muñoz
- Tarek Dendane
- Tayyba Naz Aslam
- Teobaldo Quintana
- Terje Legernaes
- Tetsuya Yumoto
- Theonymfi Papavasilopoulou
- Thomas Clark
- Thomas Piraino
- Thuy Nga Phan
- Tiago Leonor
- Tiago Pereira
- Tiehe Qin
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- Tim Frenzel
- Tim Smith
- Todd Rice
- Tommaso Tonetti
- Tomohito Sadahiro
- Toshikazu Abe
- Türkay Akbas
- Ulrike Buehner
- Valeria Lascari
- Valerie Banner-Goodspeed
- van Haren Frank
- Vanesa Alejandra Pavlotsky
- Venkat Sundaram
- Vera Pereira
- Victor Hugo Madrigal Robles
- Victoria McCredie
- Vijay Kumar Agrawal
- Vijayanand Palaniswamy
- Viratch Tangsujaritvijit
- Virginia Porta
- Virginie Lemiale
- Vito Fanelli
- Vitor Mendes
- Vladimir Cerny
- Volkan Inal
- Wang Ruilan
- Wei Zhang
- Weixin Zhang
- Wensen Pan
- Willy Diaz
- Willy Porras
- Wilson Oliveira Filho
- Wojciech Serednicki
- Won-Yeon Lee
- Wu Dawei
- Wunsch Hannah
- Xandra Yanina Rodriguez Tucto
- Xavier Souloy
- Xia Hongtao
- Xiang-Dong Guan
- Xiaobo Yang
- Xie Yun
- Yalim Dikmen
- Yari Gollo
- Yaseen Arabi
- Yaseen Arabi
- Yasemin Seker Tekdos
- Yazcitk Sandoval
- You Shang
- Youjin Chang
- Young Ju Lee
- Young-Jae Cho
- Young-Jae Cho
- Yuda Sutherasan
- Yufeng Feng
- Yukako Obata
- Yupeng Qi
- Yutthana Apichatbutr
- Yvette Chou-Lie
- Zafer Çukurova
- Zhang Minwei
- Zhanhong Tang
- Zheng-Jiang Xing
- Zhenglong Ye
- Zoltan Kulcsar
- Zsolt Molnar
- Zsolt Molnar
- Zsuzsanna Szabo
- Óscar Peñuelas
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2023
- Field of study
Background: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0-4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2-6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society
Performance of a modular ton-scale pixel-readout liquid argon time projection chamber
- Author
- Abed Abud Adam
- Abi Babak
- Acciarri Roberto
- Acero Mario
- Adames Marcio
- Adamov George
- Adamowski Mark
- Adams David
- Adinolfi Marco
- Adriano Cris
- Aduszkiewicz Antoni
- Aguilar Jessica
- Aimard Benjamin
- Akbar Faiza
- Allison Kyle
- Alonso Monsalve Saul
- Alrashed Munera
- Alton Andrew
- Alvarez Rodrigo
- Alves Tiago
- Amar Hamza
- Amedo Pablo
- Anderson John
- Andrade Aldana Diego
- Andreopoulos Costas
- Andreotti Mirco
- Andrews Michael P.
- Andrianala Fenompanirina
- Andringa Sofia
- Anfimov Nikolay
- Ankowski Artur
- Antoniassi Marcelo
- Antonova Maria
- Antoshkin Alexander
- Aranda-Fernandez Alfredo
- Arellano Luciano
- Arrieta Diaz Enrique
- Arroyave Manuel
- Asaadi Jonathan
- Ashkenazi Adi
- Asner David
- Asquith Lily
- Atkin Edward
- Auguste Didier
- Aurisano Adam
- Aushev Vladimir
- Autiero Dario
- Azfar Farrukh
- Back Ashley
- Back Henning
- Back John
- Bagaturia Iuri
- Bagby Linda
- Balashov Nikita
- Balasubramanian Supraja
- Baldi Pierre
- Baldini Wander
- Baldonedo Jacobo
- Baller Bruce
- Bambah Bindu
- Banerjee Rituparna
- Barao Fernando
- Barenboim Gabriela
- Barham Alzás Pablo
- Barker Gary
- Barkhouse Wayne
- Barr Giles
- Barranco Monarca Juan
- Barros Adilson
- Barros Nuno
- Barrow Daniel
- Barrow Joshua
- Basharina-Freshville Anastasia
- Bashyal Amit
- Basque Vincent
- Batchelor Charlie
- Bathe-Peters Lars
- Battat James
- Battisti Federico
- Bay Fatih
- Bazetto Maria
- Bazo Alba José Luis
- Beacom John
- Bechetoille Edouard
- Behera Biswaranjan
- Belchior Ewerton
- Bell Gerard
- Bellantoni Leo
- Bellettini Giorgio
- Bellini Vincenzo
- Beltramello Olga
- Benekos Nektarios
- Benitez Montiel Carlos
- Benjamin Douglas
- Bento Neves Francisco
- Berger Joshua
- Berkman Sophie
- Bernal Javier
- Bernardini Paolo
- Bersani Andrea
- Bertolucci Sergio
- Betancourt Minerba
- Betancur Rodríguez Amalia
- Bevan Adrian
- Bezawada Yashwanth
- Bezerra Anibal
- Bezerra Thiago
- Bhat Avinay
- Bhatnagar Vipin
- Bhatt Jayesh
- Bhattacharjee Maharnab
- Bhattacharya Meghna
- Bhuller Shyam
- Bhuyan Bipul
- Biagi Simone
- Bian Jianming
- Biery Kurt
- Bilki Burak
- Bishai Mary
- Bitadze Alexander
- Blake Andrew
- Blaszczyk Flor
- Blazey Gerald
- Blucher Edward
- Bogenschuetz Jacob
- Boissevain Jan
- Bolognesi Sara
- Bolton Timothy
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- Lehnert Ralf
- Leigui de Oliveira M.A.
- Leitner Matthaeus
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- Li Yichen
- Liao Heng-Ye
- Lin Cheng-Ju Stephen
- Lindebaum Dennis
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- Ling Jiajie
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- Menegolli A.
- Meng Guang
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- Muse Joseph
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- Qian Xin
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- Rappoldi A.
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- Ratoff Peter
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- Sensenig Jon
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- Shen Jieran
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- Steiner Herbert M.
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- Tatar E.
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- Timm Steven C.
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- Triller Elizabeth
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- Truchon Joshua
- Truncali Daniele
- Trzaska Wladyslaw
- Tsai Yu-Dai
- Tsai Yun-Tse
- Tsamalaidze Zviadi
- Tsang Ka Vang
- Tsverava Nikolozi
- Tu Shuang
- Tufanli Serhan
- Tunnell Christopher
- Turner Jessica
- Tuzi Mirald
- Tyler Jennifer
- Tyley E.
- Tzanov Martin
- Uchida Melissa
- Ureña González Julio
- Urheim Jon
- Usher Tracy
- Utaegbulam Hilary
- Uzunyan Sergey
- Vagins Mark
- Vahle Patricia
- Valder Sammy
- Valdiviesso Gustavo
- Valencia Edgar
- Valentim Rodolfo
- Valerio Pia
- Vallari Zoya
- Vallazza Erik
- Valle Jose
- Van Berg Rick
- Van de Water Richard
- van Nuland-Troost Marjolein
- Vanegas Forero David
- Vannozzi Alessandro
- Varanini Filippo
- Vargas Oliva Danaisis
- Vasina Svetlana
- Vaughan Noah
- Vaziri Kamran
- Vega Juan
- Ventura Sandro
- Verdugo Antonio
- Vergani Stefano
- Verzocchi Marco
- Vetter Kurt
- Vicenzi Matteo
- Vieira de Souza Henrique
- Vignoli Chiara
- Vilela Cristovao
- Villa Emanuele
- Viola Salvatore
- Viren Brett
- Vizcaya-Hernandez Ana
- Vrba Tomas
- Vuong Quynh
- Vázquez-Ramos Alicia
- Waldron Abigail
- Wallbank Michael
- Walsh Joseph
- Walton Tammy
- Wang Hanguo
- Wang Jingbo
- Wang Li
- Wang Michael
- Wang Xiaoran
- Wang Yi
- Warburton Karl
- Warner David
- Warsame Liban
- Wascko Morgan
- Waters David
- Watson Alan
- Wawrowska Klaudia
- Weber Alfons
- Weber Colin
- Weber Michele
- Wei Hanyu
- Weinstein Amanda
- Wenzel Hans
- Westerdale Shawn
- Wetstein Matthew
- Whalen Kathleen
- Whilhelmi James
- White Andy
- White Angela
- Whitehead Leigh
- Whittington Denver
- Wilking Michael
- Wilkinson Alexander
- Wilkinson Callum
- Wilson Fergus
- Wilson Robert
- Winter Peter
- Wisniewski William
- Wolcott Jeremy
- Wolfs Jean
- Wongjirad Taritree
- Wood Anthony
- Wood Kevin
- Worcester Elizabeth
- Worcester Matthew
- Wospakrik Marianette
- Wresilo Karolina
- Wret Clarence
- Wu Shaowei
- Wu Wanwei
- Wu Wenjie
- Wurm Michael
- Wyenberg Jason
- Xiao Yiwen
- Xiotidis Ioannis
- Yaeggy Barbara
- Yahlali Nadia
- Yandel Erin
- Yang Kang
- Yang Tingjun
- Yankelevich Alejandro
- Yershov Nikolai
- Yonehara Katsuya
- Young Tim
- Yu Bo
- Yu Haiwang
- Yu Jae
- Yu Yiding
- Yuan Wenlong
- Zaki Rowan
- Zalesak Jaroslav
- Zambelli Laura
- Zamorano Bruno
- Zani Andrea
- Zapata Noreña Oscar
- Zazueta Luis
- Zeller Geralyn
- Zennamo Joseph
- Zeug Kyle
- Zhang Chao
- Zhang Shuaixiang
- Zhao Manhong
- Zhivun Elena
- Zimmerman Eric
- Zucchelli Stefano
- Zuklin Josef
- Zutshi Vishnu
- Zwaska Robert
- Publication venue
- Publication date
- 05/03/2024
- Field of study
The Module-0 Demonstrator is a single-phase 600 kg liquid argon time projection chamber operated as a prototype for the DUNE liquid argon near detector. Based on the ArgonCube design concept, Module-0 features a novel 80k-channel pixelated charge readout and advanced high-coverage photon detection system. In this paper, we present an analysis of an eight-day data set consisting of 25 million cosmic ray events collected in the spring of 2021. We use this sample to demonstrate the imaging performance of the charge and light readout systems as well as the signal correlations between the two. We also report argon purity and detector uniformity measurements, and provide comparisons to detector simulations