Teoría y praxis en el proyecto <i>Filosofar con Niños</i>

Este texto busca revelar que si el interés no se centra en la pretensión de referir a la relación teoría- praxis, si lo que intentamos plantear es la relevancia de ambos términos incluidos en la díada, no se trata de decidir si se hará uso de una lógica deductiva o inductiva, o más bien dialéctica; que, fundamentalmente, no habría que “teorizar” sobre este problema eminentemente filosófico. (Párrafo extraído del texto a modo de resumen)Departamento de Filosofí

Teoría y praxis en el proyecto <i>Filosofar con Niños</i>

Este texto busca revelar que si el interés no se centra en la pretensión de referir a la relación teoría- praxis, si lo que intentamos plantear es la relevancia de ambos términos incluidos en la díada, no se trata de decidir si se hará uso de una lógica deductiva o inductiva, o más bien dialéctica; que, fundamentalmente, no habría que “teorizar” sobre este problema eminentemente filosófico. (Párrafo extraído del texto a modo de resumen)Departamento de Filosofí

Predictive Maintenance Model Based on Anomaly Detection in Induction Motors: A Machine Learning Approach Using Real-Time IoT Data

With the support of Internet of Things (IoT) devices, it is possible to acquire data from degradation phenomena and design data-driven models to perform anomaly detection in industrial equipment. This approach not only identifies potential anomalies but can also serve as a first step toward building predictive maintenance policies. In this work, we demonstrate a novel anomaly detection system on induction motors used in pumps, compressors, fans, and other industrial machines. This work evaluates a combination of pre-processing techniques and machine learning (ML) models with a low computational cost. We use a combination of pre-processing techniques such as Fast Fourier Transform (FFT), Wavelet Transform (WT), and binning, which are well-known approaches for extracting features from raw data. We also aim to guarantee an optimal balance between multiple conflicting parameters, such as anomaly detection rate, false positive rate, and inference speed of the solution. To this end, multiobjective optimization and analysis are performed on the evaluated models. Pareto-optimal solutions are presented to select which models have the best results regarding classification metrics and computational effort. Differently from most works in this field that use publicly available datasets to validate their models, we propose an end-to-end solution combining low-cost and readily available IoT sensors. The approach is validated by acquiring a custom dataset from induction motors. Also, we fuse vibration, temperature, and noise data from these sensors as the input to the proposed ML model. Therefore, we aim to propose a methodology general enough to be applied in different industrial contexts in the future

Is there still a place for involutional melancholia nowadays?

Ethnopharmacological relevance: Rubus niveus Thunb. plant belongs to Rosaceae family and have been used traditionally to treat wounds, burns, inflammation, dysentery, diarrhea and for curing excessive bleeding during menstrual cycle. The present study was undertaken to investigate the in vivo genotoxicity of Rubus niveus aerial parts extract and its possible chemoprotection on doxorubicin (DXR)-induced DNA damage. In parallel, the main phytochemicals constituents in the extract were determined.Materials and methods: The animals were exposed to the extract for 24 and 48 h, and the doses selected were 500, 1000 and 2000 mg/kg b.w. administered by gavage alone or prior to DXR (30 mg/kg b.w.) administered by intraperitoneal injection. The endpoints analyzed were DNA damage in bone marrow and peripheral blood cells assessed by the alkaline alkaline (pH &gt; 13) comet assay and bone marrow micronucleus test.Results and conclusion: The results of chemical analysis of the extract showed the presence of tormentic acid, stigmasterol, quercitinglucoronide (miquelianin) and niga-ichigoside F1 as main compounds. Both cytogenetic endpoints analyzed showed that there were no statistically significant differences (p &gt; 0.05) between the negative control and the treated groups with the two higher doses of Rubus niveus extract alone, demonstrating absence of genotoxic and mutagenic effects. Aneugenic/clastogenic effect was observed only at 2000 mg/kg dose. On the other hand, in the both assays and all tested doses were observed a significant reduction of DNA damage and chromosomal aberrations in all groups co-treated with DXR and extract compared to those which received only DXR. These results indicate that Rubus niveus aerial parts extract did not revealed any genotoxic effect, but presented some aneugenic/clastogenic effect at higher dose; and suggest that it could be a potential adjuvant against development of second malignant neoplasms caused by the cancer chemotherapic DXR. (C) 2015 Elsevier Ireland Ltd. All rights reserved.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Cost-effective approach to lung cancer risk for a radiological dispersal device (RDD) scenario

A release of radioactive material into the environment can lead to hazardous exposure of the population and serious future concerns about health issues such as an increased incidence of cancer. In this context, a practical methodology capable of providing useful basic information from the scenario can be valuable for immediate decisions and future risk assessment. For this work, the simulation of a radiological dispersal device (RDD) filled with americium-241 was considered. The radiation dose simulated by the HotSpot code was used as an input to the epidemiological equations from BEIR V producing the data used to assess the risk of lung cancer development. The methodology could be useful in providing training for responders aimed to the initial support addressed to decision-making for emergency response at the early phase of an RDD scenario. The results from the simulation allow estimating (a) the size of the potentially affected population, (b) the type of protection action considering gender and location of the individuals, (c) the absorbed doses, (d) the matrix of lung cancer incidence predictions over a period of 5 years, and (e) the cost-effectiveness in the initial decision environment

Serum Alanine Aminotransferase Levels, Hematocrit Rate and Body Weight Correlations Before and After Hemodialysis Session

PURPOSE: To evaluate alanine aminotransferase levels before and after a hemodialysis session and to correlate these values with the hematocrit rate and weight loss during hemodialysis. PATIENTS AND METHODS: The serum alanine aminotransferase levels, hematocrit rate and body weight were measured and correlated before and after a single hemodialysis session for 146 patients with chronic renal failure. An receiver operating characteristic (ROC) curve for the serum alanine aminotransferase levels collected before and after hemodialysis was plotted to identify hepatitis C virus-infected patients. RESULTS: The mean weight loss of the 146 patients during hemodialysis was 5.3% (p < 0.001). The mean alanine aminotransferase levels before and after hemodialysis were 18.8 and 23.9 IU/, respectively, denoting a significant 28.1% increase. An equally significant increase of 16.4% in the hematocrit rate also occurred after hemodialysis. The weight loss was inversely correlated with the rise in both the alanine aminotransferase level (r = 0.3; p < 0.001) and hematocrit rate (r = 0.5; p < 0.001). A direct correlation was found between the rise in alanine aminotransferase levels and the hematocrit during the hemodialysis session (r = 0.4; p < 0.001). Based on the ROC curve, the upper limit of the normal alanine aminotransferase level should be reduced by 40% relative to the upper limit of normal if the blood samples are collected before the hemodialysis session or by 60% if blood samples are collected after the session. CONCLUSION: In the present study, significant elevations in the serum alanine aminotransferase levels and hematocrit rates occurred in parallel to a reduction in body weight after the hemodialysis session. These findings suggest that one of the factors for low alanine aminotransferase levels prior to hemodialysis could be hemodilution in patients with chronic renal failure

Histological evaluation on Brazilian green propolis effect in tissue repair of Wistar rats cutaneous wounds

This study aimed to evaluate the action of Brazilian green propolis (5%) topic use on cutaneous wound healing in rats, by inflammatory cell counting. Ten Wistar rats were separated in groups 24 h and 72 h, were trichotomized under anesthesia on cervical-dorsal region, and 2 wounds were provoked with a biopsy punch (5 mm diameter). Left wound underwent Brazilian green propolis topic treatment, and right wounds received nothing. Tissue samples were processed for light microscopy with hematoxilineosin., and leucocytes, macrophages and fibroblasts were counted using a histometric reticule in ocular lens. In both groups, within 24 and 72 h evolution, treated wounds demonstrated significant bigger means for leucocytes, macrophages and fibroblasts. Brazilian green propolis resulted in inflammatory cell quantity increase, suggesting its action on tissue repair process.Colegio de Farmacéuticos de la Provincia de Buenos Aire

The MHC Gene Region of Murine Hosts Influences the Differential Tissue Tropism of Infecting Trypanosoma cruzi Strains

We have previously demonstrated that both parasite genetic variability and host genetic background were important in determining the differential tissue distribution of the Col1.7G2 and JG T. cruzi monoclonal strains after artificial infections in mice. We observed that the JG strain was most prevalent in hearts of mouse lineages with the MHC haplotype H-2d (BALB/c and DBA2), while Col1.7G2 was predominant in hearts from C57BL/6 mice, which have the H-2b haplotype. To assess whether the MHC gene region indeed influenced tissue tropism of T. cruzi, we used the same two parasite strains to infect C57BL/6 (H-2b) and C57BLKS/J (H-2d) mice; the latter strain results from the introgression of DBA2 MHC region into the C57BL/6 background. We also performed ex vivo infections of cardiac explants from four congenic mice lineages with the H-2b and H-2d haplotypes arranged in two different genetic backgrounds: C57BLKS/J (H-2d) versus C57BL/6 (H-2b) and BALB/c (H-2d) versus BALB/B10-H2b (H-2b). In agreement with our former observations, Col1.7G2 was predominant in hearts from C57BL/6 mice (H-2b), but we observed a clear predominance of the JG strain in hearts from C57BLKS/J animals (H-2d). In the ex vivo experiments Col1.7G2 also prevailed in explants from H-2b animals while no predominance of any of the strains was observed in H-2d mice explants, regardless of the genetic background. These observations clearly demonstrate that the MHC region influences the differential tissue distribution pattern of infecting T. cruzi strains, which by its turn may be in a human infection the determinant for the clinical forms of the Chagas disease

BIM en la universidad

126 páginas.La tecnología BIM (Building Information Modeling, por sus siglas en inglés) es un método innovador para facilitar la comunicación entre los sectores de la arquitectura, ingeniería y construcción, donde se genera intercambio de información de manera eficiente, se crean representaciones digitales (modelosv3d ricos en información) de todas las fases del proceso de construcción y simulan el rendimiento en la vida real, lo que perfecciona el flujo de trabajo, aumenta la productividad y mejora la calidad. En México se realizó un estudio en la industria de la construcción (Bim Forum México, encuesta 2017), que analiza las razones por las que las empresas no utilizan BIM; las que destacan que: las licencias y equipos son muy caros (29%), no se cuenta con personal calificado (23%), los clientes no lo requieren (5%), la industria mexicana no está preparada (4%), no hay capacitación en ello (3%), no hay tiempo para implementarlo (2%), etc. Ante tales razones, los desafíos a los que se enfrenta el sector académico es implementar dentro de sus programas de estudio la enseñanza la tecnología BIM para la formación de nuevas generaciones de profesionales (arquitectos e ingenieros) que cuenten con los conocimientos y habilidades necesarias para responder a los retos que se enfrenta la industria de la construcción. El presente documento se enfoca a estudios realizados por académicos de diversas universidades: Worcester Polytechnic Institute, USA; Universidad Politécnica de Madrid; Universidad Autónoma de Yucatán, México; y Universidad Autónoma Metropolitana, Unidad Azcapotzalco, México. Las investigaciones han sido acerca de la experiencia en la implementación de la tecnología BIM en la práctica y en el proceso de enseñanza aprendizaje