11 research outputs found

    2020年我国英文科技期刊发展回顾

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    收集2020年中国新批准CN号的英文科技期刊名录及卓越行动计划高起点新刊批准情况,整理2020年SCI和Scopus数据库新收录中国英文科技期刊情况,基于JCR数据库分析中国科技期刊学术影响力,回顾2020年影响中国英文科技期刊的重要政策和事件,并就预印本、载文量、引入社会资本等影响中国英文科技期刊发展的几个问题进行了讨论

    Effects of different kinds of media on the growth and active metabolite production of algicolous marine fungus PT2

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    本文采用PD、GPY、YES、SYE、GPM 5种不同培养基培养海藻真菌菌株PT2,并对其在不同培养基中的生长情况、代谢产物的形成及抗肿瘤活性进行分析,旨在了解不同培养基对菌株生长和活性物质合成的影响.结果显示,PT2菌株在不同培养基上的培养特征及生长速率有所不同,液体培养基发酵液抽提物的抗肿瘤活性也有较大差别,其中SYE发酵液抽提物活性最强,对KB、Raji和Hela 3种肿瘤细胞的IC50分别为 7. 6μg/cm3、2. 4μg/cm3和 3. 3μg/cm3.采用HPLC法对不同抽提物进行分析,发现它们之间的组成成分有显著差异.本文的实验结果表明,不同培养基对该菌株的生长及活性代谢产物的合成具有显著的影响.Algicolous marine fungus PT2 was cultivated on five different kinds of media which are PD, GPY, YES, SYE and GPM. The growth status, secondary metabolite production of fungus PT2 and anti-tumor activities of extracts from fungus PT2 were analyzed to study the effects of different media on growth and active metabolite production of fungus PT2. The results showed that it was different in culture characters and growth rates of PT2 on different media. There were also various inhibiting effects on tumor cells by five culture broth extracts, the activity of extract from SYE was highest in KB,Raji and Hela tumor cells, IC_(50) was 7.6μg/mm~3, (2.4μg/mm~3) and (3.3μg/mm~3) respectively. Culture extracts of fungus PT2 from five media were determinated by HPLC method and there was significant difference in compositions of extracts. The results indicated that there are distinct effects of different media on growth and active metabolite production of PT2.国家高科技研究发展计划资助项目(2001AA620401);; 福建省自然科学基金资助项目(C0210001

    The Effects of Different Media on Antitumor Active Substances Production of Mangrove Fungus HTF3

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    对红树林真菌HTF3菌株在PD、GPY、YES、GPM及SYE 5种不同培养基中的生长情况、抗肿瘤活性及代谢产物的形成进行了研究,旨在了解培养基对该菌株生长及抗肿瘤活性物质合成的影响.结果显示:在不同的培养基中,HTF3菌株的生长速率不同,抗肿瘤活性及抗瘤谱也有明显差异;采用HPLC对不同培养基发酵液乙酸乙酯抽提物进行分析,发现不同抽提物的色谱峰数、色谱峰的保留时间及紫外吸收值均有较大的不同.实验结果表明:不同培养基对HTF3菌株抗肿瘤活性物质的合成有显著影响.Mangroves are special woody plant communities in the intertidal zone of tropical and subtropical coasts.Mangrove fungi growing in mangroves are attractive because a variety of chemically interesting and biologically significally substances have been purified from their secondary metabolites.Therefore,this paper studied the growth,antitumor activities and metabolites production of mangrove fungus HTF3 on potato dextrose medium,glucose peptone yeast extract medium,yeast extract sucrose medium,glucose peptone malt extract medium and starch yeast extract medium,to find out the effects of different media on the growth and antitumor active substances production of HTF3.The results showed that the growth rates of HTF3 on different solid media were different;the growth rates of HTF3 on glucose peptone yeast extract medium and starch yeast extract medium was 17.1mm/d and 11.1 mm/d;antitumor activities and antitumor specffum were markedly different in different liquid media,the IC_(50) against Raji cell of five extracts from different fermentation broth,namely A(PD),B(GPY),C(YES),D(GPM) and E(SYE) is 31.9,66.5,76,49.6 and 27.6 μg/mL respectively.The ethyl acetate extracts of the fermentation broth from different media were analysed using HPLC.The numbers of chromatographic peak,retention times and UV spectra were significant different.The study indicated diffetent media greatly affected the antitumor active substances production of HTF3.国家863计划(2001AA620401);; 福建省科技计划项目(2004N003)资

    高超声速非平衡流动-辐射特性数值模拟研究

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    飞行器高超声速飞行过程中所承受对流加热和辐射加热可能具有相当的量级,因此合理准确预测气动加热需要将二者进行综合考虑.文章发展了具有非玻尔兹曼电子能级分布和振动能级分布的高温空气碰撞辐射模型,并耦合一维激波后流动方程计算不同飞行条件下激波后的非平衡流动特性,采用逐线辐射输运模型计算获得激波后非平衡辐射特性、辐射强度和辐射输运通量,深入比较分析了不同飞行高度和马赫数对非平衡流动和辐射输运过程的影响.计算结果表明对于高空高马赫飞行条件,其波后流动存在显著的热力学非平衡、化学非平衡和能级非平衡特征,在近激波区域高振动能级和原子高束缚电子激发态明显低于玻尔兹曼分布.在高空高马赫条件下真空紫外辐射占据主导地位,主要是由高能原子束缚-束缚跃迁造成的.随着高度和马赫数的下降,激波层内气体解离和电离程度降低,原子辐射贡献下降,分子辐射贡献增加,导致红外、可见光和紫外波段的辐射输运增强,真空紫外辐射输运过程减弱

    磁暴期间环电流的纬向移动与倾斜现象

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    先进型油井堵水方法研究

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    该项目研究了先进型油井堵水新概念的内涵;油井区块整体堵水的决策技术;油井深部堵水合理深度的决定;油井的选择性堵剂与选择性注入方法;封堵不同来水方法;油井堵水与其他措施结合的协同效应;典型的矿场试验例。从油井区块整体堵水、深部堵水、选择性堵水、不同来水堵水和与各种措施结合的堵水5个方面建立先进型油井堵水的概念和相应的技术,并进行了矿场试验,使油井堵水成为得力的提高原油采收率方法

    新疆城镇体系的理论与实践

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    从人地关系和人与自然和谐发展角度构建了新疆城镇体系地域系统框架,形成适合新疆区情的类型多样、尺度转换交融的城镇空间理论结构。不仅从单因素对新疆城市化和城镇体系的影响进行剖析,而且从时间尺度、空间尺度和科技进步三维勾勒出新疆城市化和城镇体系发展的动力机制。提出了走以大中城市和区域性中心城市以及重点小城镇优先发展、注重城市功能扩张和完善、集约化和内涵型的新疆城镇化发展道路。提出了重组乌鲁木齐大都市圈,以及北疆铁路沿线城镇密集带、南疆铁路沿线城镇发展带、沿线城镇发展带构成的“一圈、三带”的新疆城镇体系空间组合及发展模式。提出了以城镇发展为核心的统筹规划方案,突出了生态环境分区划调整等理论与实践问题

    JUNO Sensitivity on Proton Decay pνˉK+p\to \bar\nu K^+ Searches

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    The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in pνˉK+p\to \bar\nu K^+ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via pνˉK+p\to \bar\nu K^+ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is 9.6×10339.6 \times 10^{33} years, competitive with the current best limits on the proton lifetime in this channel

    JUNO sensitivity on proton decay pνK+p → νK^{+} searches

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