Design and Implementation of Patent Case Management Information System

当前时代正处于知识经济的时代，知识产权作为知识经济的重要组成部分，越来越引起各个国家的重视，专利即是知识产权的一个重要分支。专利代理事务所作为专业的专利服务机构，其对专利的发展和应用具有重要作用。专利代理事务所在成立之初，其规模相对较小，人员较少，每个人所承担的事务相对较多。在专利案件管理方面，很多还停留在使用一个个数据表格的方式进行管理，并没有一个完整的管理信息系统来实现对案件的管理。基于解决专利案件的管理的目的，论文对专利代理事务所的专利案件管理信息系统进行了研究和讨论。 本系统采用基于B/S的架构，使用Dreamweaver和VisualBasic.NET工具进行开发，使用ACCESS...In the age of knowledge economy, Intellectual Property, as the main part of knowledge economy, attracts more and more attention from every country. Patent is one of its significant branches. As the professional patent service office, patent agencies play an important role in the development and application of patent. At the beginning of agencies’ establishment, they are small with few staffs. Ever...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323217

Design and Implementation of Rural Power Production Safety Management System for Jiangxi Power Company

农电企业，承担着广大农村的电力供应，维护供电秩序、保障安全供电是每一个农电企业必须面对的课题。随着经济的快速发展，电力负荷也同步快速增加。如何依靠科技进步，顺应市场经济大潮，提高农电企业自身管理现代化、科学化水平，实现人民电业为人民，以用电客户为中心的宗旨，提供良好的服务，不仅关系到农电企业优质服务的形象，而且也直接关系到增供、扩销和经济效益以及社会效益。因此，认真研究和探讨农村供电所安全生产、安全供电、安全用电的新举措，创新安全工作局面，是当务之急，也是夯实农村供电所安全工作基础，提升农电安全管理水平的必然趋势。 本研究为江西省电力公司开发一款以江西省电力公司农电系统为整体的纵向生产安全管...It's the responsibility of rural power company to supply the electricity to vast rural areas, keeping the supply order and ensuring the security of electricity supply was a topic which each rural power company must face. With the rapid economic development, the power load was simultaneously increasing rapidly. How to rely on scientific and technological progress, adapt to the market economy, impro...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201023015

企业经营决策风险认知的实证研究

企业经营决策风险认知的实证研究李剑锋（中国人民大学工商管理学院）徐联仓（中国科学院心理研究所）一、引言风险认知是风险研究领域新近兴起的热点课题。与传统的风险分析不同，风险认知研究采用心理科学方法，关注的是普通老百姓主观上如何觉知、如何评估、如何表征风..

Measurement of Tide Variation of the Earth with Laser Double Beam Interference Mathod

本文提出利用激光双光束干涉方法研究地球潮的变化，对其测量原理和测量精度作了分析、讨论。通过对干涉条纹进行调制并计数，在激光波长为0.63μM时，对25M的测量精度可达1/100干涉级次（0.006μM）。因此，在隧道中用这个方法可测地球潮。In this paper,the measurement of tide variation of the earth has been studied by using laser double beam Interference method.We have discussed the measuring principle and precision.The results show that the precision is of 0.006 m at =6 328,length 25 m by modulating and counting of interferogram.So the mathod may be used to measure the tide variation of the earth in tunnel.福建省自然科学基

Progress in the Development of Microwave High Power SiGe HBT's and Its Applications

文章论述了SiGe异质结双极晶体管(HBT)在微波功率领域应用的优势,详细介绍了微波功率SiGe HBT的结构设计方法,以及主要影响器件性能的材料和结构因素,评述了其最新进展及今后发展方向。国家自然科学基金重点资助项目(60336010);; 福建省青年科技人才创新项目(2004J021)资

Airborne fine particle decreases the cell viability and induces inflammation in human bronchial epithelial cells

目的:研究大气细颗粒物(fine particulate; matter,PM_(2.5))对人支气管上皮细胞活性的影响及其炎性作用。方法:用PM_(2.5)采样器采集上海地区大气PM_(2.5)样本,扫; 描电镜观察PM_(2.5)形态特征。将人支气管上皮细胞BEAS-2B暴露于不同浓度(0,50,100,200,400,800; mug/mL)的PM_(2.5) 12,24,48 h,细胞活力检测试剂盒(cell counting kit-8,; CCK-8)法检测PM_(2.5)暴露对细胞活性的影响。实时定量PCR(quantitative real-time; PCR,qRT-PCR)检测细胞粒细胞-巨噬细胞集落刺激因子(granulocyte-macrophage colony stimulating; factor,GM-CSF)和TNF-alpha mRNA的表达,Western印迹检测; GM-CSF和TNF-alpha蛋白的表达。结果:扫描电镜观察发现,PM_(2.5)形态多样,大小不一,直径大多等于或小于2.5; mum。与同时间点未暴露组比较,各暴露组(50~800; mug/mL)细胞活性呈不同程度的下降,差异具有统计学意义(P<0.05)。与未暴露组比较,暴露于100,400或800 mug/mL; PM_(2.5) 24 h后,GM-CSF和TNF-alpha; mRNA和蛋白表达水平明显升高(P<0.05),且PM_(2.5)暴露浓度越高,GM-CSF和TNF-alpha的mRNA和蛋白升高水平越显著。; 结论:大气PM_(2.5)可引起人支气管上皮细胞的炎症反应,降低细胞活性,这可能与PM_(2.5)促发和加重支气管肺部炎性疾病有关。Objective: To investigate the effects of airborne fine particle on cell; viability and inflammation in human bronchial epithelial cells. Methods:; Atmospheric PM_(2.5) samples were collected by PM_(2.5) sampler.; PM_(2.5) morphology was observed by scanning electron microscope (SEM).; Human bronchial epithelial cells (BEAS- 2B) were treated with PM_(2.5); at different concentrations (0, 50, 100, 200, 400, 800 mug/mL) for 12,; 24 or 48 hours, and the cell activity were evaluated by cell counting; kit-8 (CCK-8). The mRNA expression levels of (granulocyte-macrophage; colony stimulating factor,GM-CSF) and TNF-alpha were detected by; quantitative real-time PCR (qRT-PCR). Western blot was used to detect; the protein expressions of GM-CSF and TNF-alpha. Results: According to; SEM, the shape of PM_(2.5) varied, and the diameter was different and; mostly equal to or less than 2.5 mum. CCK-8 assay showed that different; concentrations of PM_(2.5) exposure for 12 hours, 24 hours and 48 hours; resulted in loss of cell viability of BEAS-2B cells (P<0.05). Different; concentrations of PM_(2.5) increased the mRNA and protein expression of; GM-CSF and TNF-alpha, and the higher concentration of PM_(2.5) induced; higher expression, which have statistical significant difference between; the groups (P<0.05). Conclusion: Atmospheric PM_(2.5) can cause; inflammatory response in human bronchial epithelial cells. They can; reduce cell viability, which may be related to the PM_(2.5) trigger and; aggravation of bronchopulmonary inflammatory diseases

基于大数据平台的城市灾害社会恢复力指标初探——以“莫兰蒂”台风为例

气候变化导致许多灾害的发生频率加快,破坏强度增加,提高城市的韧性是当前应对气候变化的重要途径。作为韧性的核心内容,社会恢复力对于灾后恢复评估及灾害的社会影响评估具有重要意义。本文以大数据为背景,关注公众心理恢复,探究反映社会恢复能力的指标及其与受灾情况之间的关系,对厦门市展开了实证分析。研究结果表明:厦门市的公众心理恢复时间最长,三明市最短;公众对莫兰蒂台风的关注度与其登陆的时间和地点有关,随台风在时空上的逼近而增高;表征关注度的公众搜索指数和公众心理恢复时间这两个反映社会恢复能力的指标都表现出与受灾情况良好的正相关性,可以作为社会恢复力的评价指标,但各自的影响机制不同,有待深入研究

Optical Bistability of EBBA Liquid Crystal

利用光自聚焦和f-P腔两种手段，对EbbA液晶进行了光学双稳态研究。实验是在60μM液晶薄膜中采用连续Ar＋激光器进行，确定出温度与光学双稳态和多级光学双稳态回线的关系，讨论了EbbA液晶在固态相和液晶相及其相变过程中光学双稳态的机制。Using self focusing and Fabry Perot cavity arrangements,the optical bistability and multiple bistability of EBBA nematic liquid crystal films have been studied.The experiment was carried out with Ar + CW laser and samples of 60 μm thickness.The temperature dependence of the bistable and multiple bistable loops has been measured.The related mechanism of optical bistability in solid phase,nematic phase and phase transition of liquid crystalb.国家自然科学基金;福建省自然科学基

Rapid determination of 1,2-propylene glycol and glycerol in refill fluids for electronic cigarettes by Raman spectroscopy

为实现电子烟烟液主要成分的简便快速检测,建立了同时测定电子烟烟液中1,2-丙二醇和丙三醇含量的拉曼光谱分析方法,利用该方法测定了17个电子烟烟液; 样品,并与气质联用法进行了结果比较。结果表明:①1,2-丙二醇和丙三醇分别在0.125~0.956和0.106~1.120; g/mL时,以522和671 cm~(-1)特征信号峰强度绘制的标准工作曲线线性关系良好(R~2>; 0.999),单样本和独立样本t检验结果证实方法的准确性较高。②17个电子烟烟液样品中,1,2-丙二醇和丙三醇的含量分别为0.533~0.766; 和0.182~0.476; g/mL。该方法与气质联用法检测结果的配对样本t检验结果表明,在95%置信概率下,两种方法的定量结果一致。该方法不需进行样品前处理,更适用于批量; 电子烟烟液中1,2-丙二醇和丙三醇的快速定量分析。A simple and rapid Raman spectroscopy method for simultaneous; determination of 1,2-propylene glycol and glycerol in refill fluids for; electronic cigarettes was developed. Samples of 17 refill fluids were; analyzed by a portable Raman spectrometer,and the data were compared; with those determined by GC-MS. The results showed that: 1) The standard; curves of 1,2-propylene glycol and glycerol determined at the Raman; intensity of 522 and 671 cm~(-1) possessed good correlation coefficients; (R~2 above 0.999) in the content range of 0.125-0.956 and 0.106-1.120; g/mL,respectively. The results of one sample t-test and independent; sample t-test indicated that the Raman method was accurate. 2) The; contents of 1,2-propylene glycol and glycerol in 17 refill fluids were; in the range of 0.533-0.766 and 0.182-0.476 g/mL, respectively. The; result of paired sample t-test showed that the data determined by Raman; spectroscopy were consistent with those obtained by GC-MS at a; confidence level of 95%. Without sample pretreatment, Raman spectroscopy; method is simple to operate and more suitable for the rapid quantitative; determination of 1,2-propylene glycol and glycerol in batches of refill; fluids for electronic cigarettes.浙江中烟工业有限责任公司科技项

Preparation and Application of Soluble Human Squamous Cell Carcinoma Antigen Expressed by Escherichia coli

旨在建立基于大肠杆菌表达系统的高效可溶性表达人鳞状上皮细胞癌抗原(SCCAg)方法,获得具有较好活性的重组SCCAg抗原并应用于建立抗原检测方法; 。基于pGEX-6P-l载体和大肠杆菌E. coli; ER2566菌株开展重组SCCAg抗原可溶性表达纯化方法研究,评价纯化抗原活性,筛选特异性单克隆抗体,初步建立并评价SCCAg抗原检测方法。结果; 显示,pGEX-6P-l载体和E coli; ER2566菌株可用于建立较高效的可溶性表达和纯化SCCAg抗原的方法,获得了具有较高纯度和活性的重组SCCAg抗原,筛选获得特异性单克隆抗体并; 初步建立了 SCCAg管式化学发光检测方法。建立了有效的基于大肠杆菌表达系统的可溶性表达和纯化SCCAg的方法。The aims of this study are to establish a method for efficient soluble; expression of human squamous cell carcinoma antigen(SCCAg ) based on; Escherichia coli expression system and obtain the recombinant SCCAg; antigen in fine activity, then apply it in the detection method; establishment of antigen. The study on the method of soluble expression; and purification of recombinant SCCAg antigen was conducted based on; pGEX-6P-l vector and E. coli ER2566 strain. The activity of the purified; antigen was evaluated by Abbott Kit and the specific monoclonal antibody; was screened by indirect ELISA. It was proved that PGEX-6P-1 vector and; E. coli strain ER2566 could be used to establish efficient soluble; expression and purification method for recombinant SCCAg antigen.; Moreover, the recombinant SCCAg antigen was proved to be in high purity; and activity. Thus,the SCCAg detection method of chemical luminous tube; was established with the specific monoclonal antibodies. In conclusion,; an effective method for the expression and purification of SCCAg, which; is based on the E. coli expression system, is established.国家高技术研究发展计划(863计划