1,772 research outputs found

    Quick release connector Patent

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    Design and development of quick release connecto

    Re-visiting the Health Care Luxury Good Hypothesis: Aggregation, Precision, and Publication Biases?

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    While a growing literature examining the relationship between income and health expenditures suggests that health care is a luxury good, this conclusion is contentiously debated due to heterogeneity of the existing results. This paper tests the luxury good hypothesis using meta-regression analysis, taking into consideration publication selection, precision, and aggregation bias. The findings suggest that publication bias exists, a result that is robust irrespectively of the tests employed. Precision and aggregation bias also appear to play a role in the generation of estimates. The corrected income elasticity estimates range from 0.26 to 0.84, although we cannot reject the luxury good hypothesis for some of the performed corrections.aggregate health expenditure, luxury good, regional health expenditure, health care, income elasticity, meta-regression analysis

    Crónica del seminario europeo «Derecho administrativo de la información y administración transparente: hacia un nuevo modelo de Administración pública

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    To dispose and receive information are fundamental rights and essential elements of the socalled «information society». For this to be possible and allow all citizens to participate on equal basis, it is crucial to have an administration able to provide information, wherein openness and transparency are absolute priorities. That being said, the seminar analyzes the legal framework and the development of the principle of transparency in the Spanish Law, European Community Law and the Law of certain countries of the European Union, for its limited ordinance on the right of access to information that has been carried out, as well as the sectorial arrangement of publicity of the public policyEl derecho a disponer de información y a recibirla son elementos esenciales de la llamada sociedad de la información, y para que ésta sea posible y el ciudadano pueda participar en condiciones de igualdad, se necesita una actividad administrativa de información, en la que la transparencia juega un papel de primer orden. Sentado lo anterior, el seminario analiza el marco jurídico y el desarrollo del principio de transparencia en el Derecho español, comunitario y también en determinados Derecho nacionales de países de la Unión Europea, tanto por la limitada regulación del derecho de acceso a la información que se ha llevado a cabo, como por la ordenación sectorial de la publicidad de la actuación pública

    Jurisprudència ambiental a la Comunitat Valenciana

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    A lo largo del año 2011 los pronunciamientos del Tribunal Superior de Justicia de la Comunidad Valenciana relacionados con el medio ambiente han sido numerosos y de gran variedad temática; ello puede tener dos lecturas: por una parte, que los daños al medio ambiente se han convertido, lamentablemente, en una constante; por otra, con carácter positivo, el mayor control que los tribunales hacen del medio natural, favoreciendo su protecciónAl llarg de l’any 2011 els pronunciaments del Tribunal Superior de Justícia de la Comunitat Valenciana relacionats amb el medi ambient han estat nombrosos i de gran varietat temàtica. Això pot tenir dues lectures: d’una banda, lamentablement que els danys al medi ambient s’han convertit en una constant; i de l’altra, amb caràcter positiu, el control més gran que els tribunals fan del mitjà natural, que n’afavoreix la proteccióThroughout the year 2011 a large number of rulings on a wide range of topics concerning the environment were issued by the Valencian Community High Court of Justice. This can be interpreted in two ways: on the one hand, cases of damage to the environment have unfortunately become a recurring issue and, on the other, in a more positive vein, the law courts are exerting greater control over the environment, which favours its protectio

    Derecho y políticas ambientales en la Comunidad Valenciana (Segundo semestre 2016)

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    Derecho y políticas ambientales en la Comunidad Valenciana (Segundo semestre 2016

    Jurisprudencia ambiental en la Comunidad Valenciana (Segundo semestre 2016)

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    Jurisprudencia ambiental en la Comunidad Valenciana (Segundo semestre 2016

    Gene Orthology Inference via Large-Scale Rearrangements for Partially Assembled Genomes

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    Recently we developed a gene orthology inference tool based on genome rearrangements (Journal of Bioinformatics and Computational Biology 19:6, 2021). Given a set of genomes our method first computes all pairwise gene similarities. Then it runs pairwise ILP comparisons to compute optimal gene matchings, which minimize, by taking the similarities into account, the weighted rearrangement distance between the analyzed genomes (a problem that is NP-hard). The gene matchings are then integrated into gene families in the final step. Although the ILP is quite efficient and could conceptually analyze genomes that are not completely assembled but split in several contigs, our tool failed in completing that task. The main reason is that each ILP pairwise comparison includes an optimal capping that connects each end of a linear segment of one genome to an end of a linear segment in the other genome, producing an exponential increase of the search space. In this work, we design and implement a heuristic capping algorithm that replaces the optimal capping by clustering (based on their gene content intersections) the linear segments into m ? 1 subsets, whose ends are capped independently. Furthermore, in each subset, instead of allowing all possible connections, we let only the ends of content-related segments be connected. Although there is no guarantee that m is much bigger than one, and with the possible side effect of resulting in sub-optimal instead of optimal gene matchings, the heuristic works very well in practice, from both the speed performance and the quality of computed solutions. Our experiments on real data show that we can now efficiently analyze fruit fly genomes with unfinished assemblies distributed in hundreds or even thousands of contigs, obtaining orthologies that are more similar to FlyBase orthologies when compared to orthologies computed by other inference tools. Moreover, for complete assemblies the version with heuristic capping reports orthologies that are very similar to the orthologies computed by the optimal version of our tool. Our approach is implemented into a pipeline incorporating the pre-computation of gene similarities
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