20 research outputs found
Sparse Estimation using Bayesian Hierarchical Prior Modeling for Real and Complex Linear Models
In sparse Bayesian learning (SBL), Gaussian scale mixtures (GSMs) have been
used to model sparsity-inducing priors that realize a class of concave penalty
functions for the regression task in real-valued signal models. Motivated by
the relative scarcity of formal tools for SBL in complex-valued models, this
paper proposes a GSM model - the Bessel K model - that induces concave penalty
functions for the estimation of complex sparse signals. The properties of the
Bessel K model are analyzed when it is applied to Type I and Type II
estimation. This analysis reveals that, by tuning the parameters of the mixing
pdf different penalty functions are invoked depending on the estimation type
used, the value of the noise variance, and whether real or complex signals are
estimated. Using the Bessel K model, we derive a sparse estimator based on a
modification of the expectation-maximization algorithm formulated for Type II
estimation. The estimator includes as a special instance the algorithms
proposed by Tipping and Faul [1] and by Babacan et al. [2]. Numerical results
show the superiority of the proposed estimator over these state-of-the-art
estimators in terms of convergence speed, sparseness, reconstruction error, and
robustness in low and medium signal-to-noise ratio regimes.Comment: The paper provides a new comprehensive analysis of the theoretical
foundations of the proposed estimators. Minor modification of the titl
Improved prediction of radiation-induced hypothyroidism in nasopharyngeal carcinoma using pre-treatment CT radiomics
Abstract When planning radiation therapy, late effects due to the treatment should be considered. One of the most common complications of head and neck radiation therapy is hypothyroidism. Although clinical and dosimetric data are routinely used to assess the risk of hypothyroidism after radiation, the outcome is still unsatisfactory. Medical imaging can provide additional information that improves the prediction of hypothyroidism. In this study, pre-treatment computed tomography (CT) radiomics features of the thyroid gland were combined with clinical and dosimetric data from 220 participants to predict the occurrence of hypothyroidism within 2 years after radiation therapy. The findings demonstrated that the addition of CT radiomics consistently and significantly improves upon conventional model, achieving the highest area under the receiver operating characteristic curve (AUCs) of 0.81 ± 0.06 with a random forest model. Hence, pre-treatment thyroid CT imaging provides useful information that have the potential to improve the ability to predict hypothyroidism after nasopharyngeal radiation therapy