Current Advance and Future Prospects of Tissue Engineering Approach to Dentin/Pulp Regenerative Therapy

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ING2 (inhibitor of growth protein-2) plays a crucial role in preimplantation development

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TGF-β1-induced differentiation of SHED into functional smooth muscle cells

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Power and Scale: The Shifting Geography of Industrial Relations Law in Australia

In an increasingly complex literature exploring the geographies of socially constructed scale, interest has focused on the relationship between scale, power and the contested political terrains through which these relations are played out. In this paper, I argue that these interactions must be understood in specific contexts, where shifts in scale are inextricably linked to shifts in the sources and instruments of power. By applying a scale perspective to the analysis of recent industrial relations legislation in Australia, I show that the nature and direction of rescaling is “fixed” by the powers of institutional actors and the scope of their jurisdictions. I then draw on the distinctively scaled relations of the Australian context to assess the extent to which Australia's national rescaling processes can be seen as representing a process of convergence toward universal “spaces of neoliberalism”

Multiple sclerosis susceptibility alleles in African Americans.

Multiple sclerosis (MS) is an autoimmune demyelinating disease characterized by complex genetics and multifaceted gene-environment interactions. Compared to whites, African Americans have a lower risk for developing MS, but African Americans with MS have a greater risk of disability. These differences between African Americans and whites may represent differences in genetic susceptibility and/or environmental factors. SNPs from 12 candidate genes have recently been identified and validated with MS risk in white populations. We performed a replication study using 918 cases and 656 unrelated controls to test whether these candidate genes are also associated with MS risk in African Americans. CD6, CLEC16a, EVI5, GPC5, and TYK2 contained SNPs that are associated with MS risk in the African American data set. EVI5 showed the strongest association outside the major histocompatibility complex (rs10735781, OR=1.233, 95% CI=1.06-1.43, P-value=0.006). In addition, RGS1 seems to affect age of onset whereas TNFRSF1A seems to be associated with disease progression. None of the tested variants showed results that were statistically inconsistent with the effects established in whites. The results are consistent with shared disease genetic mechanisms among individuals of European and African ancestry

A Gelatin-sulfonated Silk Composite Scaffold based on 3D Printing Technology Enhances Skin Regeneration by Stimulating Epidermal Growth and Dermal Neovascularization

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PTH[1-34] improves the effects of core decompression in early-stage steroid-associated osteonecrosis model by enhancing bone repair and revascularization

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Indoor environmental quality and occupant satisfaction in green-certified buildings

Green building certification systems aim at improving the design and operation of buildings. However, few detailed studies have investigated whether green rating leads to higher occupant satisfaction with indoor environmental quality (IEQ). This research builds on previous work to address this. Based on the analysis of a subset of the Center for the Built Environment Occupant Indoor Environmental Quality survey database featuring 11,243 responses from 93 LEED-rated office buildings, we explored the relationships between the points earned in the IEQ category and the satisfaction expressed by occupants with the qualities of their indoor environment. We found that the achievement of a specific IEQ credit did not substantively increase satisfaction with the corresponding IEQ factor, while the rating level, and the product and version under which certification had been awarded, did not affect workplace satisfaction. There could be several reasons for this lack of relationships, some of which are outside the control of designers and beyond the scope of rating systems based primarily on design intent. We conclude with a discussion of the challenges and priorities that building professionals, researchers, and green building certification systems need to consider for moving us towards more comfortable, higher performing, and healthier green-rated buildings

The outlook of building information modeling for sustainable development

As human needs evolve, information technologies and natural environments require a wider perspective of sustainable development, especially when examining the built environment that impacts the central of social-ecological systems. The objectives of the paper are (a) to review the status and development of building information modeling (BIM) in regards to the sustainable development in the built environment, and (b) to develop a future outlook framework that promotes BIM in sustainable development. Seven areas of sustainability were classified to analyze forty-four BIM guidelines and standards. This review examines the use of BIM in sustainable development, focusing primarily on certain areas of sustainability, such as project development, design, and construction. The developed framework describes the need for collaboration with the multiple disciplines for the future adoption and use of BIM for the sustainable development. It also considers the integration between “BIM and green assessment criteria”; and “BIM and renewable energy” to address the shortcomings of the standards and guidelines