983 research outputs found

    Airy functions over local fields

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    Airy integrals are very classical but in recent years they have been generalized to higher dimensions and these generalizations have proved to be very useful in studying the topology of the moduli spaces of curves. We study a natural generalization of these integrals when the ground field is a non-archimedean local field such as the field of p-adic numbers. We prove that the p-adic Airy integrals are locally constant functions of moderate growth and present evidence that the Airy integrals associated to compact p-adic Lie groups also have these properties.Comment: Minor change

    Effect of C-terminal truncations on the aggregation propensity of A53E, a familial mutant of α-Synuclein: An Insilico Study

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    α-Synuclein, an intrinsically disordered protein, is well known for its role on the onset of Parkinson’s Disease (PD), a neurodegenerative disorder. In α-synuclein, several mutations have been known to cause genetic forms of PD. Recently a new familial mutant, A53E of α-synuclein was discovered in a family and found to accelerate the α-synuclein gene, SNCA. But the molecular details about the A53E α-synuclein aggregation were not well studied. It has been recently suggested that two C-terminally truncated α-synuclein (αS C-X): 120 and 123, along with the A53E mutation would cause a more aggressive pathology and an increase in aggregation. So here we demonstrate the effect of C-terminal truncations along with A53E mutation on the aggregation propensity of α-synuclein by comparing the conformational dynamics of A53E full length protein and its C-terminal truncations using molecular dynamics simulation methods. In A53E full length protein we observed stability to be more and also hydrophobic surface (NAC (non-amyloid β component) region), number of molecular interactions and interface area between monomeric units to be relatively less than αS C-X. Our findings in this study suggest that more the residues removed from the C-terminal along with A53E mutation have significant effect on the aggregation propensity of α-synuclein

    Pengaruh belanja daerah terhadap pertumbuhan ekonomi dan kemiskinan Kabupaten/Kota di Provinsi Jambi

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    The ability of local governments to manage finances is stated in the regional revenue and expenditure budget (APBD). The higher the regional expenditure allocation in the APBD, the higher the level of economic growth to reduce or alleviate the level of poverty. The variables that affect economic growth and poverty include regional expenditure. This study aims to determine the effect of regional spending on economic growth and poverty in regencies/cities in Jambi province partially or collectively. The analytical method used is simple regression analysis with a panel data model. The results showed that regional spending has a negative and partially insignificant effect on economic growth. Regional expenditure has a positive and minor impact on poverty levels in districts/cities in Jambi Province. Keywords: Local government, Economic growth, Poverty

    Filling the gaps: ethnobotanical study of the Garrigues district, an arid zone in Catalonia (NE Iberian Peninsula)

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    [Background]: This study has focused on the Garrigues district, one of the most arid regions in Catalonia (NE Iberian Peninsula), which, in general terms, has remained unexplored from the ethnobotanical point of view. This area, of 22,243 inhabitants, comprises 33 municipalities distributed across 1123.12 km2. The natural vegetation is dominated by holm oak forests and maquis called ‘garriga’, the latter giving its name to the district. During the last few decades, this landscape has been transformed by agricultural activities, nowadays in recession. The main aim of this work was to collect and analyse the ethnoflora of this area in order to fill a gap in the ethnobotanical knowledge in Catalonia.[Methods]: The followed methodology was based on semi-structured interviews. The obtained data have been qualitatively and quantitatively analysed and compared with other available ones.[Results]: Data were gathered from 68 interviews involving 101 informants, whose ages range from 24 to 94, the mean being 73.07. The number of taxa reported in this study was 420, belonging to 99 botanical families. The interviewed informants referred 4715 use reports (UR) of 346 useful taxa, 1741 (36.93) of them corresponding to medicinal uses, 1705 (36.16%) to food uses, and 1269 (26.91%) to other uses. This study has inventoried, apart from individual plant uses, 260 plant mixtures, of which 98 are medicinal and 162 food. In the present study, 849 vernacular names with 116 phonetic variants have been collected, as well, for 410 taxa. The informant consensus factor (FIC) obtained for our interviewees is 0.93, and the ethnobotanicity index is 23.47% for the studied area. Apart from plants belonging to the typical Catalan, Iberian or European ethnofloras, the present work contributes information on some plants from semiarid or arid regions, such as Artemisia herba-alba and Plantago albicans, much rarer in the ethnobotany of the quoted areas.[Conclusions]: The results of this study reveal the persistence of ethnobotanical knowledge in the prospected area and the importance of filling the existing gaps in the ethnofloristic sampling of the Catalan territories. The almost complete dataset, now including some arid territories, will allow us to carry out a global analysis and to provide an accurate overview.This research was supported by projects 2017SGR001116 from the Generalitat de Catalunya (Catalan Government), PRO2017-S02VALLES and PRO2020-S02VALLES from the Institut d’Estudis Catalans (IEC, Catalan Academy of Sciences and Humanities) and CSO2014-59704-P and CGL2017-84297-R from the Spanish Government. AG received a predoctoral grant of the Universitat de Barcelona (APIF 2015-2018).Peer reviewe

    VIII Jornades d’Etnobotànica en Llengua Catalana

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    Noticia publicada en la web institutcional del Instituto Botánico de Barcelona el 10 de junio de 2016 -- Disponibles PDFs en español y catalán y capturas de pantalla de la noticia en la web.Peer reviewe

    An empirical study to understand the effectiveness and scope of Blockchain Technology in Indian Public sector

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    The Blockchain is a distributed database that is maintained as Blocks and contains all transactions or digital occurrences. These are the records of transactions that take place between parties.Blockchain blocks are kept as blocks and shared among participants. Each Block is examined, validated, and saved by the parties who are a part of the system/network, each brick is unique and contains the details of a single transaction as well as the transaction\u27s hash key. The study offers insights to researchers about the opportunity threat and future use of blockchain in the public sector

    Influence du traitement thermique sur l'usinabilité du laiton monophasé

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    La connaissance des propriétés et du comportement d’un matériau en usinage est primordiale pour optimiser son utilisation et obtenir une usinabilité maximale. Dans ce but, l’étude de la modification de la ductilité par traitement thermiques sur plusieurs critères d’usinabilité tels que les efforts de coupe, la rugosité, les bavures et la formation du copeau a été menée sur le laiton monophasé. A cette fin, l’influence du traitement thermique sur la microstructure du laiton a d’abord été étudiée. La taille des grains et la dureté ont permis de déterminer les propriétés mécaniques des états métallurgiques. Des essais de perçage ont ensuite été effectués sur les états métallurgiques H01 (99HV), OS100 (88HV) et OS250 (47HV) pour regarder l’influence du traitement thermique sur l’usinabilité. Cette étude expérimentale a permis de comprendre l’influence du taux de laminage et de la température de recuit sur les propriétés mécaniques. Les essais d’usinabilité ont ensuite permis de prouver que les efforts de coupe sont dépendants des conditions de coupe mais pas de la ductilité dans les états métallurgiques testés. La taille des bavures augmente avec la ductilité et la vitesse de coupe, et diminue avec l’avance. La rugosité de la surface des trous après l’usinage a également été étudiée. Il a aussi été prouvé par une étude sur les copeaux que la température croît avec la vitesse de coupe. L’analyse de la segmentation des copeaux n’a en revanche pas permis de trouver une corrélation significative avec les traitements thermiques testés. Enfin, le revêtement de l’outil a montré une grande importance sur l’usinabilité du matériau. Il a été conclu que l’usinabilité du laiton C26000 (CuZn30) est meilleure lorsqu’on travaille dans un état métallurgique dur. Ces conclusions sont valables pour le laiton monophasé étudié, il serait intéressant d’examiner aussi le cas des laitons biphasés

    Plants and mental disorders: the case of Catalan linguistic area

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    Introduction: Mental disorders are among the leading causes of ill-health and disability worldwide. Despite the disease burden they cause, including significant direct and indirect impacts on individual’s health and major social and economic consequences in all countries of the world, it is still one of the most neglected areas of public health. In such a context, the medicinal plants traditionally used to pale these pathologies are presented as a promising tool for future drug development for the management of mental health disorders. The aim of the present study is to analyze the information about plant species used to treat mental disorders in the Catalan linguistic area (CLA) and compare these traditional uses with pharmacological literature in order to evaluate the most quoted taxa and their uses and to provide a basis for further research. Methods: Data have been recovered from the “Etnobotànica dels Països Catalans” webpage (https://etnobotanica.iec.cat/) and the meta-analytic work carried out in the present study covers 27 prospections performed in different territories between 1990 and 2019. Descriptive statistics and quantitative ethnobotany were carried out and some ethnobotanical indices were calculated. Results and Discussion: The number of use reports analysed to treat mental disorders in CLA is 2,544 spread over 183 taxa belonging to 64 families, being the most cited the Malvaceae (29.36% of use reports), Lamiaceae (16.71%), Caprifoliaceae (7.94%), Rutaceae (7.47%) and Papaveraceae (6.01%). The most used taxa to treat or alleviate the mental disorders have been Tilia platyphyllos Scop. (24.53%), Valeriana officinalis L. (7.47%), Salvia officinalis L. (5.07%), Sambucus nigra L. (4.28%), and Ruta chalepensis L. (3.89%). The flowers or inflorescences (47.68%), followed by aerial part (23.49%), have been the most used plant parts, and tisane the most commonly used pharmaceutical form (78.03%). The most reported use is as sedative with 40.92%, followed by anticephalalgic (21. 19%) and tranquilizer (20.01%). The informant consensus factor (FIC) was 0.93, and 3.72% was the ethnobotanicity index (EI) value. The information is coincidental with at least one of the comprehensive pharmacological literature sources checked for 73.68% of ethnobotanical uses

    Charge Carrier Extraction by Linearly Increasing Voltage:Analytic framework and ambipolar transients

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    Up to now the basic theoretical description of charge extraction by linearly increasing voltage (CELIV) is solved for a low conductivity approximation only. Here we present the full analytical solution, thus generalize the theoretical framework for this method. We compare the analytical solution and the approximated theory, showing that especially for typical organic solar cell materials the latter approach has a very limited validity. Photo-CELIV measurements on poly(3-hexyl thiophene-2,5-diyl):[6,6]-phenyl-C61 butyric acid methyl ester based solar cells were then evaluated by fitting the current transients to the analytical solution. We found that the fit results are in a very good agreement with the experimental observations, if ambipolar transport is taken into account, the origin of which we will discuss. Furthermore we present parametric equations for the mobility and the charge carrier density, which can be applied over the entire experimental range of parameters.Comment: 8 pages, 5 figure
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