668 research outputs found

    When Words Fail: The Use and Misuse of Narratives in the Prison Abolition Movement

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    Inspired in part by my experiences at that internship, and a newfound appreciation for the impact of stories, this paper explores the role of narratives in the way we talk and think about prisons. Narratives, or storytelling, are not neutral accounts of the way the world works but are rather informed by social structures of power and control, necessitating subjecting them to critique and analysis. When used for social movements, this becomes especially true. In this paper, I will analyze how narratives are written/spoken and disseminated as part of the abolition or criminal justice reform movement. In organizations and movements that are reformist, I demonstrate that narratives follow neoliberal logic, and are individualizing, rely on free market ideology, and depend upon short-term organizing. As a result, these narratives not only reflect the carceral state, but continuously uphold it. In opposition, narratives used by organizations that are expressly abolitionist resist individualization, short-term organizing, and recognize the carceral state’s operations as rooted in white supremacy, effectively pushing for abolition and improving the lives of incarcerated people. Overall, I argue that narratives are incredibly important tools for exposing the harsh conditions of incarceration and the truths of the carceral state; but when fighting for abolition, narratives must be subject to critique and analysis

    Zirconium-group 13 heterobinmetallic compounds and the synthesis of oxysulfides in sodium polysulfide

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    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1996.Includes bibliographical references.by Francis Mark de Rege.Ph.D

    MEIO AMBIENTE DO TRABALHO, SAÚDE MENTAL E DIGNIDADE DA PESSOA HUMANA: A SAÚDE DO TRABALHADOR COMO DIREITO HUMANO

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     Este artigo aborda a proteção da saúde mental do trabalhador no meio ambiente de trabalho pautada no princípio da dignidade humana enquanto vetor de proteção aos direitos humanos em todos os âmbitos, inclusive no que tange à proteção da saúde psíquica nos espaços de trabalho. Neste sentido, objetiva-se analisar os aspectos normativos e principiológicos que viabilizam e dão sustentáculos à defesa do trabalhador contra as violências psíquicas sofridas no meio ambiente do trabalho. Tal defesa está ancorada, sobretudo, no princípio da dignidade da pessoa humana como elemento central na proteção dos direitos humanos que entre outros aspectos estabelece constitucionalmente no âmbito da ordem econômica o dever de assegurar a dignidade dos trabalhadores no meio ambiente do trabalho. Embora verifique-se no ordenamento jurídico ausência de lei proibitiva específicas de violências psíquicas no meio ambiente de trabalho, sua tutela que pode ser estabelecida a partir do princípio da dignidade da pessoa humana, alinhado aos direitos fundamentais do meio ambiente de trabalho equilibrado e o direito à saúde mental do trabalhador visando a proteção/preservação de sua saúde psíquica do trabalhador. Nesta senda, o direito à proteção da saúde mental no meio ambiente do trabalho é direito à saúde enquanto direito fundamental, e também direito ao meio ambiente do trabalho sadio, adequado e equilibrado, direito este que deve ser garantido, viabilizado e fiscalizado pelo Estado, sendo esse o principal responsável pela sua efetividade. Nesta pesquisa a metodologia aplicada foi a qualitativa usando-se como procedimento a revisão bibliográfica para maior compreensão do objeto de estudo.

    O PROCESSO DE DESENVOLVIMENTO DOS DIREITOS FUNDAMENTAIS E SUAS DIMENSÕES HISTÓRICAS

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    Este artigo tem por objetivo analisar o desenvolvimento histórico dos direitos fundamentais e de suas dimensões enquanto fases históricas da positivação destes direitos. Entender o processo evolutivo dos direitos fundamentais é compreender a história da limitação do poder do Estado e o estabelecimento de direitos e garantias fundamentais à dignidade humana. O desenvolvimento histórico dos direitos fundamentais ocorreu em três fases, primeiramente com o desenvolvimento da filosofia e da religião no mundo antigo, posteriormente com a afirmação dos direitos naturais do homem e pela elaboração de suas doutrinas, e finalmente com a afirmação e positivação dos direitos fundamentais nas diversas declarações de direitos e constituições. A partir desta última fase os direitos fundamentais são estudados a partir de dimensões históricas que são os diferentes momentos de declarações, positivações e transformações desses direitos em relação aos seus conteúdos, titularidade, eficácia e efetivação. O estudo se deteve apenas nas três primeiras dimensões que versam sobre os direitos fundamentais individuais, sociais e coletivos por serem as dimensões clássicas abordadas pela doutrina majoritária. Nesta pesquisa a metodologia aplicada foi a qualitativa usando-se como procedimento a revisão bibliográfica para maior compreensão do objeto de estudo

    Importance of cone beam computed tomography for diagnosis of calcifying cystic odontogenic tumour associated to odontoma : report of a case

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    The calcifying cystic odontogenic tumour (CCOT) is a rare benign cystic neoplasm not infrequently associated with odontoma. This report documents a case of CCOT associated with compound odontoma arising in the anterior maxilla in a 25-year-old woman. Conventional radiographs showed a large calcified mass with poorly visualized radiolucent margins. The extent and condition of the internal structure of the CCOT associated with odontoma was able to be determined based on radiographic findings from cone beam computed tomography. This advanced image technique proved to be extremely useful in the radiographic assessment of this particular neoplasm of the jawbones

    Pre-heating mitigates composite degradation

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    Dental composites cured at high temperatures show improved properties and higher degrees of conversion; however, there is no information available about the effect of pre-heating on material degradation. Objectives This study evaluated the effect of pre-heating on the degradation of composites, based on the analysis of radiopacity and silver penetration using scanning electron microscopy/energy-dispersive X-ray spectroscopy (SEM/EDS). Material and Methods Thirty specimens were fabricated using a metallic matrix (2x8 mm) and the composites Durafill VS (Heraeus Kulzer), Z-250 (3M/ESPE), and Z-350 (3M/ESPE), cured at 25°C (no pre-heating) or 60°C (pre-heating). Specimens were stored sequentially in the following solutions: 1) water for 7 days (60°C), plus 0.1 N sodium hydroxide (NaOH) for 14 days (60°C); 2) 50% silver nitrate (AgNO3) for 10 days (60°C). Specimens were radiographed at baseline and after each storage time, and the images were evaluated in gray scale. After the storage protocol, samples were analyzed using SEM/EDS to check the depth of silver penetration. Radiopacity and silver penetration data were analyzed using ANOVA and Tukey’s tests (α=5%). Results Radiopacity levels were as follows: Durafill V

    K30, H150, and H168 Are Essential Residues for Coordinating Pyridoxal 5′-Phosphate of O-Acetylserine Sulfhydrylase from Acidithiobacillus ferrooxidans

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    O-acetylserine sulfhydrylase (OASS) is a key enzyme involved in the pathway of the cysteine biosynthesis. The gene of OASS from Acidithiobacillus ferrooxidans ATCC 23270 was cloned and expressed in E. coli, the soluble protein was purified by one-step affinity chromatography to apparent homogeneity. Colors and UV–vis scanning results of the recombinant protein confirmed that it was a pyridoxal 5′-phosphate (PLP)-containing protein. Sequence alignment and site-directed mutation of the enzyme revealed that the cofactor PLP is covalently bound in Schiff base linkage with K30, as well as the two residues H150 and H168 were the crucial residues for PLP binding and stabilization

    Genetic Screening for Potential New Targets in Chronic Myeloid Leukemia Based on Drosophila Transgenic for Human BCR-ABL1

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    Chronic myeloid leukemia is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome that originates from the reciprocal translocation t(9;22)(q34;q11.2) and encodes for the constitutively active tyrosine kinase protein BCR-ABL1 from the Breakpoint Cluster Region (BCR) sequence and the Abelson (ABL1) gene. Despite BCR-ABL1 being one of the most studied oncogenic proteins, some molecular mechanisms remain enigmatic, and several of the proteins, acting either as positive or negative BCR-ABL1 regulators, are still unknown. The Drosophila melanogaster represents a powerful tool for genetic investigations and a promising model to study the BCR-ABL1 signaling pathway. To identify new components involved in BCR-ABL1 transforming activity, we conducted an extensive genetic screening using different Drosophila mutant strains carrying specific small deletions within the chromosomes 2 and 3 and the gmrGal4,UAS-BCR-ABL1 4M/TM3 transgenic Drosophila as the background. From the screening, we identified several putative candidate genes that may be involved either in sustaining chronic myeloid leukemia (CML) or in its progression. We also identified, for the first time, a tight connection between the BCR-ABL1 protein and Rab family members, and this correlation was also validated in CML patients. In conclusion, our data identified many genes that, by interacting with BCR-ABL1, regulate several important biological pathways and could promote disease onset and progression

    On the Breeds of Cattle—Historic and Current Classifications

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    Classification of cattle breeds contributes to our understanding of the history of cattle and is essential for an effective conservation of genetic diversity. Here we review the various classifications over the last two centuries and compare the most recent classifications with genetic data. The classifications devised during the 19th to the late 20th century were in line with the Linnaean taxonomy and emphasized cranial or horn morphology. Subsequent classifications were based on coat color, geographic origin or molecular markers. Several theories were developed that linked breed characteristics either to a supposed ancestral aurochs subspecies or to a presumed ethnic origin. Most of the older classifications have now been discarded, but have introduced several Latin terms that are still in use. The most consistent classification was proposed in 1995 by Felius and emphasizes the geographic origin of breeds. This is largely in agreement with the breed clusters indicated by a biochemical and molecular genetic analysis, which reflect either groups of breeds with a common geographic origin or single breeds that have expanded by export and/or crossbreeding. We propose that this information is also relevant for managing the genetic diversity of cattl
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