4,113 research outputs found
Kerkarchitectuur na 2000:Het ontwikkelen van grensverleggende typologieën vanuit het samenspel tussen liturgie, architectuur en duurzame ontwikkeling
Future challenges to microbial food safety
Despite significant efforts by all parties involved, there is still a considerable burden of foodborne illness, in which micro-organisms play a prominent role. Microbes can enter the food chain at different steps, are highly versatile and can adapt to the environment allowing survival, growth and production of toxic compounds. This sets them apart from chemical agents and thus their study from food toxicology. We summarize the discussions of a conference organized by the Dutch Food and Consumer Products Safety Authority and the European Food Safety Authority. The goal of the conference was to discuss new challenges to food safety that are caused by micro-organisms as well as strategies and methodologies to counter these. Management of food safety is based on generally accepted principles of Hazard Analysis Critical Control Points and of Good Manufacturing Practices. However, a more pro-active, science-based approach is required, starting with the ability to predict where problems might arise by applying the risk analysis framework. Developments that may influence food safety in the future occur on different scales (from global to molecular) and in different time frames (from decades to less than a minute). This necessitates development of new risk assessment approaches, taking the impact of different drivers of change into account. We provide an overview of drivers that may affect food safety and their potential impact on foodborne pathogens and human disease risks. We conclude that many drivers may result in increased food safety risks, requiring active governmental policy setting and anticipation by food industries whereas other drivers may decrease food safety risks. Monitoring of contamination in the food chain, combined with surveillance of human illness and epidemiological investigations of outbreaks and sporadic cases continue to be important sources of information. New approaches in human illness surveillance include the use of molecular markers for improved outbreak detection and source attribution, sero-epidemiology and disease burden estimation. Current developments in molecular techniques make it possible to rapidly assemble information on the genome of various isolates of microbial species of concern. Such information can be used to develop new tracking and tracing methods, and to investigate the behavior of micro-organisms under environmentally relevant stress conditions. These novel tools and insight need to be applied to objectives for food safety strategies, as well as to models that predict microbial behavior. In addition, the increasing complexity of the global food systems necessitates improved communication between all parties involved: scientists, risk assessors and risk managers, as well as consumer
Dealing with artficially dichotomized variables in Meta-Analytic Structural Equation Modeling
The support for farmer-led seed systems in African seed laws.
The synthesis report is part of a series of papers on Integrated Seed Sector Development (ISSD) in Africa’s thematic working group on Matching national realities with global commitments. The thematic working group addressed the main question on how African governments implement their global commitments while fostering a viable pluralistic sector. The main hypothesis was that making these commitments more coherent with the practices and realities of farmers and creating an enabling environment for strengthening multiple seed systems will increase farmers’ access to quality seed. Three main topics were discussed under this theme: access and benefit sharing for climate resilient seed systems; national and regional seed laws that support the development of a robust, integrated seed sector that supports smallholder farmers' needs; and creating room for informal and intermediary seed systems in a UPOV '91 informed Plant Variety Protection system.
The study was conducted to answer a key question on how the various national and regional seed laws relate to the diversity of seed systems that exist in a given country. More specifically how current seed laws affect informal (farmer-based) seed systems and in what manner seed laws can be adapted to support these seed systems. Policies, laws and regulations of 32 African countries were carefully reviewed to identify some best practices and key issues and challenges in regulation. Findings from the study indicate that the main challenge for many African countries is that their seed regulations don’t include provisions that support farmer -led seed systems. As a way forward, there is need for revision of existing regulatory frameworks to takes into account the needs and characteristics of the various seed systems in order to increase the availability of quality seed of preferred varieties for all farmers
Operationalizing perpetrator studies. Focusing readers’ reactions to The Kindly Ones by Jonathan Littell
Within the field of Holocaust Studies the last decade has witnessed a turn to the figure of the perpetrator, who had hitherto received little attention due to ethical, legal and psychological reasons. A similar turn can also be observed in connection with the study of empathy. In this context, the concept of “negative empathy,” intended as a sharing of emotions with morally negative fictional characters, has become an increasingly discussed topic. For research in this area, the novel The Kindly Ones (2006) by Jonathan Littell takes up a privileged position in light of its intrinsic literary quality and due to its commercial and critical success. This novel recounts the memories of an SS-officer, Maximilian Aue, who participated in the Shoah. We have carried out an experiment using some passages of this novel to test the empathic reactions of (104) readers. Passages were presented under either of two conditions: as a fictional text or as part of an autobiography. Results showed that fictionalization has a significant effect on moral disengagement; readers who read the narrative presented to them as fictional experienced higher levels of moral disengagement compared to readers in the autobiography condition. Moreover, higher levels of moral disengagement led to significantly higher levels of empathy for the protagonist of the novel
Mach's Principle and Model for a Broken Symmetric Theory of Gravity
We investigate spontaneous symmetry breaking in a conformally invariant
gravitational model. In particular, we use a conformally invariant scalar
tensor theory as the vacuum sector of a gravitational model to examine the idea
that gravitational coupling may be the result of a spontaneous symmetry
breaking. In this model matter is taken to be coupled with a metric which is
different but conformally related to the metric appearing explicitly in the
vacuum sector. We show that after the spontaneous symmetry breaking the
resulting theory is consistent with Mach's principle in the sense that inertial
masses of particles have variable configurations in a cosmological context.
Moreover, our analysis allows to construct a mechanism in which the resulting
large vacuum energy density relaxes during evolution of the universe.Comment: 9 pages, no figure
Midportion Achilles Tendinopathy
Abstract
The aim
of this thesis was to elucidate the effect of different treatment options in midportion Achilles tendinopathy, with optimizing current diagnostic methods. For this purpose we conducted two randomised controlled trials, a case control study, a cadaveric study, and a cross sectional study
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