Use of portable devices and confocal Raman spectrometers at different wavelength to obtain the spectral information of the main organic components in tomatoes (Solanum Lycopersicum) fruits

Tomato (Solanum lycopersicum) fruit samples, in two ripening stages, ripe (red) and unripe (green), collected from a cultivar in the North of Spain (Barrika, Basque Country), were analyzed directly, without any sample pretreatment, with two different Raman instruments (portable spectrometer coupled to a micro-videocamera and a confocal Raman microscope), using two different laser excitation wavelengths (514 and 785 nm, only for the confocal microscope). The combined use of these laser excitation wavelengths allows obtaining, in a short period of time, the maximum spectral information about the main organic compounds present in this fruit. The major identified components of unripe tomatoes were cutin and cuticular waxes. On the other hand, the main components on ripe tomatoes were carotenes, polyphenoles and polysaccharides. Among the carotenes, it was possible to distinguish the presence of lycopene from b-carotene with the help of both excitation wavelengths, but specially using the 514 nm one, which revealed specific overtones and combination tones of this type of carotene.This work has been financially supported by Research Project S-PE11-UN128 of the Basque Country government. Technical and support provided by SGIker (UPV/EHU, MICINN, GV/EJ, ESF) is gratefully acknowledged

TuCCompi: a multi-layer model for distributed heterogeneous computing with tuning capabilities

Producción CientíficaDuring the last decade, parallel processing architectures have become a powerful tool to deal with massively-parallel problems that require High Performance Computing (HPC). The last trend of HPC is the use of heterogeneous environments, that combine different computational processing devices, such as CPU-cores and GPUs (Graphics Processing Units). Maximizing the performance of any GPU parallel implementation of an algorithm requires an in-depth knowledge about the GPU underlying architecture, becoming a tedious manual effort only suited for experienced programmers. In this paper, we present TuCCompi, a multi-layer abstract model that simplifies the programming on heterogeneous systems including hardware accelerators, by hiding the details of synchronization, deployment, and tuning. TuCCompi chooses optimal values for their configuration parameters using a kernel characterization provided by the programmer. This model is very useful to tackle problems characterized by independent, high computational-load independent tasks, such as embarrassingly-parallel problems. We have evaluated TuCCompi in different, real-world, heterogeneous environments using the All-Pair Shortest-Path problem as a case study.Ministerio de Economía y Competitividad and ERDF program of the European Union: CAPAP-H5 network (TIN2014-53522-REDT), MOGECOPP project (TIN2011-25639); Junta de Castilla y Leon (Spain): ATLAS project (VA172A12-2); and the COST Program Action IC1305: NESUS

El Big Data como metodología de investigación social: propuestas, renuncias y dilemas desde la Sociología

Since the widely cited "The Coming Crisis of Empirical Sociology" (2007), Savage and Burrows fore-saw an imminent problem that empirical sociology would face, in its inability to incorporate the "trans-actional" data of cognitive capitalism into its research practice. This is due to the progressive extension of technological intermediation in the processes of social interaction, generating an important techno-scientific barrier, but above all an economic and political one, which relegates sociology (and its meth-ods) to the rearguard of social and market research. In this article, we will make a sort of archaeology of the construction of the concept of "Big Data" as hegemonic outside the social sciences; of the main methodological alternatives that have been proposed by the social sciences, and of the new perspectives that are opening up as a result of the concentration of information in a smaller number of companies.Desde el ampliamente citado “The Coming Crisis of Empirical Sociology” (2007), Savage y Burrows nos preveían de una inminente problemática a la que se enfrentaría la sociología empírica, en su incapa-cidad de incorporar los datos “transaccionales” propios del capitalismo cognitivo en su práctica investi-gativa. Esto se debe a la progresiva extensión de la intermediación tecnológica en los procesos de inter-acción social, generando una importante barrera de carácter tecnocientífico, pero sobre todo económica y política, que relega a la sociología (y sus métodos) a la retaguardia de la investigación social y de merca-do. En este artículo haremos una suerte de arqueología de la construcción del concepto de “Big Data” como hegemónico fuera de las ciencias sociales; de las principales alternativas metodológicas que se han ido proponiendo desde las mismas, y de las nuevas perspectivas que se abren a partir de la concentra-ción de la información en un menor número de empresas

Technological and infrastructure collaborative seismic research in Western Mexico

In February and March 2014, Spanish, Mexican and British scientists and technicians explored the western margin of Mexico, a region with a high occurrence of large earthquakes (> Mw = 7.5) and tsunami generation, on board the British Royal Research Ship James Cook. This successful joint cruise, named TSUJAL, was made possible thanks to a cooperative agreement between NERC and CSIC as part of the Ocean Facilities Exchange Group (OFEG), a major forum of European oceanographic institutions for the exchange of ship time, equipment and personnel. A dense geophysical data set was acquired using for the first time 6 km length seismic streamer facilities from Spain’s Consejo Superior de Investigaciones Cientificas (CSIC), usually operating in the Spanish RV Sarmiento de Gamboa, onboard the British RRS James Cook by solving all mechanical, electrical and electronic problems. The RRS James Cook in turn provides the seismic source and the acoustic, hullmounted echosounder operated by the British Natural Environment Research Council (NERC). Multiscale seismic and echosounder images unravel the subduction geometry, nature of the crust, and evidence faults and mass wasting processes. The data are crucial to estimating fault seismic parameters, and these parameters are critical to carrying out seismic hazard in Mexico, especially when considering largemagnitude earthquakes (Mw 8.0), and to constrain tsunami models.Peer Reviewe

Tipos de familias de niños y adolescentes que acuden al instituto nuevo amanecer A.B.C.

Una forma de clasificar a las familias es de acuerdo a su composición: • Familia Nuclear: Es la que está formada por el padre, la madre y los hijos. • Familia monoparental: En la que uno de los padres ha fallecido. • Familia Extensa: Formada por los padres, los hijos y otro pariente. • Familia Compuesta: Formada por los padres, los hijos y por no parientes. • Familia de Tres Generaciones: Formada por abuelos, padres e hijos. • Familia con Segundo Trabajo: Es aquella en la que la mujer representa una fuente importante de ingreso económico al hogar. • Familia de Adulto Mayor: Está formada por un anciano o por una pareja de ancianos que viven solos. • Familia de Pax de Deux: Son familias de dos personas, ejemplo, un progenitor y un hijo, o una pareja en la que los hijos se han ido. • Padre (soltero) o Madre (soltera) con hijos: Padre o madre solteros, con hijos, en los que el matrimonio no se ha realizado. Según su desarrollo: • Familia Arcaica: Es la familia en la que la mujer se dedica a las labores del hogar. La mujer juega el rol de esposa-madre. • Familia Moderna: En este tipo de familia, la mujer participa en la fuerza de trabajo y en la economía de la familia. La mujer tiene el rol de esposa-compañera y de esposa-colaboradora De acuerdo a su lugar de residencia: • Familia Rural: Es aquella familia que vive en un lugar de menos de 1,500 habitantes. • Familia Urbana: Es aquella familia que vive en un lugar de más de 1,500 habitantes. OBJETIVO Describir el tipo de familias que acuden al INA.y Describir l

Cultura Organizacional en las Empresas: Conceptos, Alcances y Propuestas Teóricas Para su Medición

El presente documento tiene como propósito identificar la definición y la evolución que existe sobre la cultura organizacional y su importancia que debe tener para las empresas reconocer los cimientos sobre el cual se construye la cultura al interior de las organizaciones y su influencia sobre el comportamiento de los miembros que la componen. La metodología empleada para este estudio es de carácter bibliográfico y transversal, por tal razón se rastreó sobre las más importantes bases de datos. Sobre los resultados se encuentran que existe variadas definiciones sobre que significa la cultura para la sociedad y la cultura organizacional, sin embargo, existe un consenso generalizado que gira alrededor de normas y creencias que tiene los individuos y que afecta su conducta en las organizaciones. Además, se expone los diferentes tipos de cultura y se presenta modelos que pretender medir la cultura que se desarrolla en las organizaciones. En cuanto a las conclusiones, es determinante para las organizaciones de toda índole, sean públicas o privadas, no dejar al azar la manera en que se desarrolla la cultura y mucho menos dejar a la suerte el comportamiento de los miembros de la organización que pondría en riesgo su adecuado desempeño y por ende el alcance de sus metas propuestas

Telehealth in Heart Failure Care during COVID-19 Pandemic Lockdown in Argentina

Background and Objectives: During the coronavirus disease 2019 (COVID-19) pandemic, virtual visits (VVs) were recommended as an innovative and necessary alternative for patients with heart failure (HF). To assess the feasibility and acceptability of VVs in patients with HF, pulmonary hypertension (PH), and heart transplant (HT). Methods: We designed a single-centre cohort study. Consecutive VVs performed in our HF unit were analysed. The period comprehended between January 1st and March 19th (before COVID-19) and March 20th and June 30th (during COVID-19) was compared. We assessed acceptability, feasibility and the need for diagnostic studies, in-person medical evaluation, and hospitalization at 30 days. Results: HF unit medical doctors conducted 22 VVs in the pre-COVID period and 416 VVs during the COVID period. The VV was able to be performed in all patients scheduled for it and 44% answered the survey. Ninety percent of the patients who answered the survey strongly agreed that VVs were easy to be carried out. All the patients “strongly agreed” or “agreed” that their health problem could be resolved. Most patients (95%) rated the global experience as very good or excellent, with an overall average rate of 9.76±0.5 out of 10. We found no differences regarding the requirement of diagnostic studies, in-person medical evaluation and hospitalization during the first month after VVs between the 2 periods. Conclusions: VVs were feasible, presented high acceptability, and the overall experience was positive in patients with HF, PH, and HT, being this modality a valuable tool that complements in-person care.Fil: Burgos, Lucrecia María. Instituto Cardiovascular de Buenos Aires; ArgentinaFil: Benzadón, Mariano. Instituto Cardiovascular de Buenos Aires; ArgentinaFil: Candiello, Alfonsina. Instituto Cardiovascular de Buenos Aires; ArgentinaFil: Cabral, Miguel Héctor. Instituto Cardiovascular de Buenos Aires; ArgentinaFil: Conde, Diego. Instituto Cardiovascular de Buenos Aires; ArgentinaFil: Alves de Lima, Alberto Enrique. Instituto Cardiovascular de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Belardi, Jorge. Instituto Cardiovascular de Buenos Aires; ArgentinaFil: Diez, Mirta. Instituto Cardiovascular de Buenos Aires; Argentin

Dissecting the peripheral stalk of the mitochondrial ATP synthase of chlorophycean algae.

peer reviewedThe algae Chlamydomonas reinhardtii and Polytomella sp., a green and a colorless member of the chlorophycean lineage respectively, exhibit a highly-stable dimeric mitochondrial F1Fo-ATP synthase (complex V), with a molecular mass of 1600kDa. Polytomella, lacking both chloroplasts and a cell wall, has greatly facilitated the purification of the algal ATP-synthase. Each monomer of the enzyme has 17 polypeptides, eight of which are the conserved, main functional components, and nine polypeptides (Asa1 to Asa9) unique to chlorophycean algae. These atypical subunits form the two robust peripheral stalks observed in the highly-stable dimer of the algal ATP synthase in several electron-microscopy studies. The topological disposition of the components of the enzyme has been addressed with cross-linking experiments in the isolated complex; generation of subcomplexes by limited dissociation of complex V; detection of subunit-subunit interactions using recombinant subunits; in vitro reconstitution of subcomplexes; silencing of the expression of Asa subunits; and modeling of the overall structural features of the complex by EM image reconstruction. Here, we report that the amphipathic polymer Amphipol A8-35 partially dissociates the enzyme, giving rise to two discrete dimeric subcomplexes, whose compositions were characterized. An updated model for the topological disposition of the 17 polypeptides that constitute the algal enzyme is suggested. This article is part of a Special Issue entitled 'EBEC 2016: 19th European Bioenergetics Conference, Riva del Garda, Italy, July 2-6, 2016', edited by Prof. Paolo Bernardi

Efficacy and Safety of Colchicine in Post-acute Myocardial Infarction Patients : A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background: Inflammation plays a key role in atherosclerotic plaque destabilization and adverse cardiac remodeling. Recent evidence has shown a promising role of colchicine in patients with coronary artery disease. We evaluated the efficacy and safety of colchicine in post-acute myocardial infarction (MI) patients. Methods: We searched five electronic databases from inception to January 18, 2021, for randomized controlled trials (RCTs) evaluating colchicine in post-acute MI patients. Primary outcomes were cardiovascular mortality and recurrent MI. Secondary outcomes were all-cause mortality, stroke, urgent coronary revascularization, levels of follow-up high-sensitivity C-reactive protein (hs-CRP), and drug-related adverse events. All meta-analyses used inverse-variance random-effects models. Results: Six RCTs involving 6,005 patients were included. Colchicine did not significantly reduce cardiovascular mortality [risk ratio (RR), 0.91; 95% confidence interval (95% CI), 0.52-1.61; p = 0.64], recurrent MI (RR, 0.87; 95% CI, 0.62-1.22; p = 0.28), all-cause mortality (RR, 1.06; 95% CI, 0.61-1.85; p = 0.78), stroke (RR, 0.28; 95% CI, 0.07-1.09; p = 0.05), urgent coronary revascularization (RR, 0.46; 95% CI, 0.02-8.89; p = 0.19), or decreased levels of follow-up hs-CRP (mean difference, −1.95 mg/L; 95% CI, −12.88 to 8.98; p = 0.61) compared to the control group. There was no increase in any adverse events (RR, 0.97; 95% CI, 0.89-1.07; p = 0.34) or gastrointestinal adverse events (RR, 2.49; 95% CI, 0.48-12.99; p = 0.20). Subgroup analyses by colchicine dose (0.5 vs. 1 mg/day), time of follow-up (30 days) showed no changes in the overall findings. Conclusion: In post-acute MI patients, colchicine does not reduce cardiovascular or all-cause mortality, recurrent MI, or other cardiovascular outcomes. Also, colchicine did not increase drug-related adverse event

La administración de sistemas en grados afines a informática

El área de administración de sistemas aparece como materia obligatoria en muchos de los planes de estudios del grado de Ingeniería en Informática; en cambio, en otras ingenierías afines no se oferta ni siquiera como asignatura optativa. A pesar de esto, en muchas de estas ingenierías la administración de sistemas se demanda en diferentes asignaturas e incluso se considera que los estudiantes deben saberla o aprenderla de forma autodidacta. En este trabajo se plantea estudiar el nivel de conocimientos de administración de sistemas que presentan los estudiantes en titulaciones afines a informática; posteriormente se plantea analizar los conocimientos del alumnado con las necesidades que presenten diferentes asignaturas en el plan de estudios. Finalmente, como resultado del trabajo, se propone un conjunto de actividades formativas o modificaciones en planes de estudio que conduzcan a que los egresados alcancen las competencias necesarias en administración de sistemas para cumplir con los objetivos de las asignaturas y los grados analizados.The area of systems administration appears as a compulsory subject in many of the curricula of the degree in Computer Engineering; on the other hand, in other related engineering degrees it is not offered even as an optional subject. Despite this, in many of these engineering degrees, operating systems management is demanded in different subjects and it is even considered that students should know-learn it or learn it in a self-taught way. In this work, it is proposed to study the level of knowledge of operating systems administration that the students present in computer-related degrees; later, it is proposed to analyze the knowledge of the students with the needs that present different subjects in the curriculum. Finally, as a result of the work, a set of training activities or changes in curricula are proposed that lead graduates to achieve the necessary competencies in system administration to meet the objectives