Instability and trajectories of buoyancy-driven annular disks: a numerical study

We investigate the stability of the steady vertical path and the emerging trajectories of a buoyancy-driven annular disk as the diameter of its central hole is varied. The steady and axisymmetric wake associated with the steady vertical path of the disk, for small hole diameters, behaves similarly to the one past a permeable disk, with the detachment of the vortex ring due to the bleeding flow through the hole. However, as the hole diameter increases, a second recirculating vortex ring of opposite vorticity forms at the internal edge of the annulus. A further increase in the hole size leads to the shrinking of these recirculating regions until they disappear. The flow modifications induced by the hole influence the stability features of the steady and axisymmetric flow associated with the steady vertical path. The fluid-solid coupled problem shows a nonmonotonic behavior of the critical Reynolds number for the destabilization of the steady vertical path, for low values of the disk's moment of inertia. However, for very large holes, with dimension approximately more than half of the external diameter, a marked increase of the neutral stability threshold is observed. The nature of the primary instability changes as the hole size increases, with large (small) amplitude oscillations of the trajectory at intermediate (very small and large) internal diameters. We then illustrate results obtained with fully nonlinear simulations of the time-dependent dynamics, together with a comparison of the linear stability analysis results. Falling styles, typically described as steady, hula-hoop, fluttering, chaotic, and tumbling, are shown to emerge as attractors for the nonlinear dynamics of the coupled fluid-structure system. The presence of a central hole does not always reduce the falling Reynolds number, and it may cause the transition from tumbling towards fluttering, from fluttering to hula-hoop, and from hula-hoop to steady, hence promoting trajectories with smaller lateral deviations from the vertical path. The observed trajectories and patterns agree well with linear stability analysis results, in the vicinity of the threshold of instability

Multifocal gastrointestinal angiosarcoma: A challenging diagnosis?

Angiosarcoma rarely involves the gastrointestinal tract. Herein, we describe the case of a 68-year-old man with haemoptysis and melena who was eventually diagnosed with multifocal angiosarcoma of the stomach, small bowel, lungs, and thyroid. The peculiarity was that the histological feature of the polypoid lesions removed at endoscopy was initially misinterpreted as benign hyperplastic polyps, whilst their neoplastic nature was clinically suspected only when the videocapsule endoscopy revealed the presence of multiple variable-sized nodules with apical erosion or active bleeding in the small bowel. Based on the very low incidence, diagnosis of angiosarcoma involving the gastrointestinal tract may be misinterpreted by both the endoscopist and pathologist

Radiographic classification of coronal plane femoral deformities in polyostotic fibrous dysplasia

Fibrous dysplasia of bone is a skeletal dysplasia with a propensity to affect the femur in its polyostotic form, leading to deformity, fracture, and pain. The proximal femur is most commonly involved with a tendency to distal progression, thereby producing the typical shepherd's crook deformity. However, there are few data on the spectrum and progression of femoral deformities in polyostotic fibrous dysplasia

Polyethylene Glycol Epirubicin-Loaded Transcatheter Arterial Chemoembolization Procedures Utilizing a Combined Approach with 100 and 200 μm Microspheres: A Promising Alternative to Current Standards

PURPOSE:To report clinical effectiveness, toxicity profile, and prognostic factors of combined 100 μm ± 25 and 200 μm ± 50 epirubicin-loaded polyethylene glycol (PEG) microsphere drug-eluting embolic transcatheter arterial chemoembolization protocol in patients with hepatocellular carcinoma. MATERIALS AND METHODS: In this prospective, single-center, single-arm study with 18 months of follow-up, 36 consecutive patients (mean age 69.9 y ± 10.8; 26 men, 10 women; 54 naïve lesions) were treated. Embolization was initiated with 100 μm ± 25 microspheres, and if stasis (10 heart beats) was not achieved, 200 μm ± 50 microspheres were administered. Each syringe (2 mL) of PEG microsphere was loaded with 50 mg of epirubicin. Results were evaluated using Modified Response Evaluation Criteria In Solid Tumors with multidetector computed tomography/magnetic resonance imaging at 1, 3-6, 9-12, and 15-18 months. Toxicity profile was assessed by laboratory testing before and after the procedure. Complications were recorded. Postembolization syndrome (PES) was defined as onset of fever/nausea/pain after the procedure. Patient/lesion characteristics and treatment results were correlated with predicted outcome using regression analysis. Child-Pugh score was A in 86.1% of patients (31/36) and B in 13.9% (5/36). RESULTS: In 10 of 21 lesions, < 2 cm in diameter (47.5%) stasis was achieved with 100 μm ± 25 microspheres only, whereas all other lesions required adjunctive treatment with 200 μm ± 50 microspheres. Reported adverse events were grade 1 acute liver bile duct injury (3/39 cases, 7.7%) and PES (grade 2; 3/39 cases, 7.7%). Complete response (CR) at 1, 3-6, 9-12, and 15-18 months was 61.1%, 65.5%, 63.63%, and 62.5%. Objective response (CR + partial response) at 1, 3-6, 9-12, and 15-18 months was 83.3%, 65.85%, 63.63%, and 62.5%. No single factor (laboratory testing, etiology, patient status, hepatic status, tumor characteristics, administration protocol) predicted outcomes except for albumin level at baseline for CR (P < .05, odds ratio = 1.09). CONCLUSIONS: The combined microsphere sizing strategy was technically feasible and yielded promising results in terms of effectiveness and toxicity

Sporadic high-grade malignant peripheral nerve sheath tumor of the hypoglossal nerve

Malignant tumors of peripheral nerve sheaths (MPNSTs) are rare malignant soft tissue tumors arising either from a peripheral nerve or from a pre-existing benign nerve sheath tumor. They occur most often in the context of Neurofibromatosis type-1 (NF-1) and are characterized by poor prognosis and aggressive behavior with a high rate of recurrence and distant metastases. We describe a 50-year-old woman who presented with right neck swelling, progressive dysphagia and tongue paresis. Imaging analysis revealed a mass involving the right parapharyngeal space. The tumor was excissed through a transcervical approach. At surgery, the tumor was strictly adherent to the hypoglossal nerve. Pathologic evaluation of the mass revealed a high-grade MPNST. Based on the pathological diagnosis, a clinical work-up for NF-1 was performed but it resulted negative. Occurrence of sporadic high-grade MPNST in the parapharyngeal space is rare and development from the hypoglossal nerve exceptional. As far as we know, only in two cases, both with clinical features consistent with NF1, the tumor was reported to be arised from the hypoglossal nerve

Stellar luminosity functions of rich star clusters in the Large Magellanic Cloud

We show the results of deep V and I HST photometry of 6 rich star clusters in the Large Magellanic Cloud with different ages and metallicities. The number of stars with measured magnitudes in each cluster varies from about 3000 to 10000. We build stellar density and surface brightness profiles for the clusters and extract half-light radii and other structural parameters for each. We also obtain luminosity functions, Phi (Mv), down to Mv ~ 6 (m/msun > 0.6), and investigate their dependence with distance from the cluster centre well beyond their half-light radius. In all clusters we find a systematic increase in the luminosity function slope with radial distance from the centre. Among the clusters displaying significant mass segregation are the two youngest in the sample: NGC 1805 and NGC 1818. For these two clusters we obtain present-day mass functions. The NGC 1818 mass function is in excellent agreement with that derived by other authors, also using HST data. They young cluster mass function slopes differ, that of NCG 1805 being systematically steeper than NGC 1818. Since these are very young stellar systems (age < 40 Myrs), these variations may reflect the initial conditions rather than evolution due to internal dynamics.Comment: 10 pages, 24 figure

Maximum gravitational-wave energy emissible in magnetar flares

Recent searches of gravitational-wave (GW) data raise the question of what maximum GW energies could be emitted during gamma-ray flares of highly magnetized neutron stars (magnetars). The highest energies (\sim 10^{49} erg) predicted so far come from a model [K. Ioka, Mon. Not. Roy. Astron. Soc. 327, 639 (2001)] in which the internal magnetic field of a magnetar experiences a global reconfiguration, changing the hydromagnetic equilibrium structure of the star and tapping the gravitational potential energy without changing the magnetic potential energy. The largest energies in this model assume very special conditions, including a large change in moment of inertia (which was observed in at most one flare), a very high internal magnetic field, and a very soft equation of state. Here we show that energies of 10^{48}-10^{49} erg are possible under more generic conditions by tapping the magnetic energy, and we note that similar energies may also be available through cracking of exotic solid cores. Current observational limits on gravitational waves from magnetar fundamental modes are just reaching these energies and will beat them in the era of advanced interferometers.Comment: 16 pages, 5 figures, 1 tabl

Design and implementation of eye tracking application for generation of augmented reality content on spatial see through display of remote and virtual control tower (RVT)

Airports are a fundamental node in the aviation system. The growth of this sector undergoes the evolution of the airports procedures and infrastructures. Air traffic control is considered to be one of the most important activity performed in an airport. This often involves numerous personnel, construction and maintenance costs etc. With the ongoing digitalisation process in various fields, the concept of remote and virtual control towers (RVT) has emerged owing to the innovation in this field. Technologies such as augmented reality (AR) have successfully paved their smooth way to bring in improvements to an RVT. The current work aims to enhance and improve the controller work in an RVT exploiting the adaption of virtual reality and AR systems. In particular, this concept is under investigation within the EU funded SESAR project: RETINA (Resilient Synthetic Vision for Advanced Control Tower Air Navigation Service Provision) and DTT (Digital Technologies for Tower). AR content generation by virtue of various display technologies are studied and, Optical Spatial See-through displays (O SSTDs) have been considered for its own advantages in developing this application. One of the necessary requirements of AR in this configuration is identified as the tracking of the operator’s point of view (eye-tracking), to provide virtual content consistent with its real position. Thus, this paper elaborates the design of specific eye-tracking system using Microsoft Kinect V2 for the virtual control tower application. The need to have binocular vision to use AR content is assessed and the interface has been tested with few subjects to evaluate the precision of the measurements detected through the proposed solution

A Strong Jet Signature in the Late-Time Lightcurve of GW170817

We present new 0.6-10 GHz observations of the binary neutron star merger GW170817 covering the period up to 300 days post-merger, taken with the Karl G. Jansky Very Large Array, the Australia Telescope Compact Array, the Giant Metrewave Radio Telescope and the MeerKAT telescope. We use these data to precisely characterize the decay phase of the late-time radio light curve. We find that the temporal decay is consistent with a power-law slope of t^-2.2, and that the transition between the power-law rise and decay is relatively sharp. Such a slope cannot be produced by a quasi-isotropic (cocoon-dominated) outflow, but is instead the classic signature of a relativistic jet. This provides strong observational evidence that GW170817 produced a successful jet, and directly demonstrates the link between binary neutron star mergers and short-hard GRBs. Using simple analytical arguments, we derive constraints on the geometry and the jet opening angle of GW170817. These results are consistent with those from our companion Very Long Baseline Interferometry (VLBI) paper, reporting superluminal motion in GW170817.Comment: 11 pages, 3 figures, 3 tables. Accepted for publication in ApJ Letter

A segmented Hybrid Photon Detector with integrated auto-triggering front-end electronics for a PET scanner

We describe the design, fabrication and test results of a segmented Hybrid Photon Detector with integrated auto-triggering front-end electronics. Both the photodetector and its VLSI readout electronics are custom designed and have been tailored to the requirements of a recently proposed novel geometrical concept of a Positron Emission Tomograph. Emphasis is put on the PET specific features of the device. The detector has been fabricated in the photocathode facility at CERN