449 research outputs found

    Reparación del cartílago articular con injerto libre de pericondrio estudio experimental

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    Ante la incapacidad de regeneración espontánea de lesiones profundas y amplias del cartílago articular, estudiamos la reparación cartilaginosa con plastias de pericondrio tomadas de la región condro-costal e implantándolas con su cara condrogénica sobre una lesión osteocondral realizada en la superficie articular rotuliana. Macroscópica e histológicamente, a la octava semana, el neocartílago formado tenía igual apariencia que el cartílago hialino normal, no existiendo separación entre el cartílago remanente y el neoformado a partir de la plastia. Estos resultados corroboran el gran potencial condrogénico del pericondrioFaced with the incapacity of spontaneous regeneration of deep and extensive lesions of the articular cartilage we studied the cartilaginous repair with pericondrium grafts taken from the chondro-costal region. Grafts were implanted with their condrogenic face over an osteochondral defect located at the surface of the patella. At the 8th week, the neocartilage formed had macroscopically and histologically, the same appearance as the normal hyaline cartilage, with no separation between the remaining cartilage and the neocartilage induced by the graft. These results corroborate the high chondrogenic potential of the perichondrium

    The optical counterpart of the bright X-ray transient Swift J1745-26

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    We present a 30-day monitoring campaign of the optical counterpart of the bright X-ray transient Swift J1745-26, starting only 19 minutes after the discovery of the source. We observe the system peaking at i' ~17.6 on day 6 (MJD 56192) to then decay at a rate of ~0.04 mag/day. We show that the optical peak occurs at least 3 days later than the hard X-ray (15-50 keV) flux peak. Our measurements result in an outburst amplitude greater than 4.3 magnitudes, which favours an orbital period < 21 h and a companion star with a spectral type later than ~ A0. Spectroscopic observations taken with the GTC-10.4 m telescope reveal a broad (FWHM ~ 1100 km/s), double-peaked H_alpha emission line from which we constrain the radial velocity semi-amplitude of the donor to be K_2 > 250 km/s. The breadth of the line and the observed optical and X-ray fluxes suggest that Swift J1745-26 is a new black hole candidate located closer than ~7 kpc.Comment: 5 pages, 4 figures, accepted for publication in MNRA

    Roles of non-coding RNA in sugarcane-microbe interaction

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    Studies have highlighted the importance of non-coding RNA regulation in plant-microbe interaction. However, the roles of sugarcane microRNAs (miRNAs) in the regulation of disease responses have not been investigated. Firstly, we screened the sRNA transcriptome of sugarcane infected with Acidovorax avenae. Conserved and novel miRNAs were identified. Additionally, small interfering RNAs (siRNAs) were aligned to differentially expressed sequences from the sugarcane transcriptome. Interestingly, many siRNAs aligned to a transcript encoding a coppertransporter gene whose expression was induced in the presence of A. avenae, while the siRNAs were repressed in the presence of A. avenae. Moreover, a long intergenic non-coding RNA was identified as a potential target or decoy of miR408. To extend the bioinformatics analysis, we carried out independent inoculations and the expression patterns of six miRNAs were validated by quantitative reverse transcription-PCR (qRT-PCR). Among these miRNAs, miR408—a copper- microRNA—was downregulated. The cleavage of a putative miR408 target, a laccase, was confirmed by a modified 50RACE (rapid amplification of cDNA ends) assay. MiR408 was also downregulated in samples infected with other pathogens, but it was upregulated in the presence of a beneficial diazotrophic bacteria. Our results suggest that regulation by miR408 is important in sugarcane sensing whether microorganisms are either pathogenic or beneficial, triggering specific miRNA-mediated regulatory mechanisms accordingly

    Dynamical masses of a nova-like variable on the edge of the period gap

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    We present the first dynamical determination of the binary parameters of an eclipsing SW Sextantis star in the 3–4 h orbital period range during a low state. We obtained time-resolved optical spectroscopy and photometry of HS 0220+0603 during its 2004–2005 low-brightness state, as revealed in the combined Small & Moderate Aperture Research Telescope System, IAC80 and M1 Group long-term optical light curve. The optical spectra taken during primary eclipse reveal a secondary star spectral type of M5.5 ± 0.5 as derived from molecular band-head indices. The spectra also provide the first detection of a DAB white dwarf in a cataclysmic variable. By modelling its optical spectrum we estimate a white dwarf temperature of 30 000 ± 5000 K. By combining the results of modelling the white dwarf eclipse from ULTRACAM light curves with those obtained by simultaneously fitting the emission- and absorption-line radial velocity curves and I-band ellipsoidal light curves, we measure the stellar masses to be M1 = 0.87 ± 0.09 M⊙ and M2 = 0.47 ± 0.05 M⊙ for the white dwarf and the M dwarf, respectively, and an inclination of the orbital plane of i ≈ 79°. A radius of 0.0103 ± 0.0007 R⊙ is obtained for the white dwarf. The secondary star in HS 0220+0603 is likely too cool and undersized for its mass
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