Generalized contractive mappings on quasimetric spaces

In this paper, we introduce a new class of generalized contractive mappings to establish a fixed point theorem for this class of mappings in complete quasimetric spaces. In fact, at first we present the notion of ordered cyclic weakly (ψ, ϕ, A, B)- contraction and then we establish a fixed point theorem for such mappings in complete ordered s-quasimetric spaces. This can be considered as an improvement of some old fixed point theorems in the literature. Finally, we provide an example to show that our result is genuine generalizations of some fixed point theorems.Publisher's Versio

The Frequency of Patients with Craniosynostosis Referred to the Department of Reconstruction and Plastic Surgery During 2006-2011

Introduction: Although cranial suture syn-ostosis as the leading cause of craniosyn-ostosis and its consequences is a relatively common disease in Iran, unfortunately there is no accurate statistics about the type and incidence of the disease in Iran. For the reason, the aim of this study was to evaluate the frequency and complications of cranios-ynostosis in Iran. Materials & Methods: Regarding to the fact that Shahid Beheshti University of Medical Sciences is a referral center for surgical ma-nagement of craniosynostois, the patients who were referred to this center and under-gone into surgical treatment, between 1996-2011 were studied retrospectively. Findings: From 222 patients who unde-rgone into surgical reconstruction for cran-iosynostosis, the most common groups were plagiocephally (right and left) (37.61%), trigonocephally (37%), brachioc-ephally (20%) and scaphocephally (4.5%) groups, respectively. Discussion & Conclusion: Since the scaph-ocephalic patients who need surgical recon-struction, are appeared normal for general population and even for physicians, so their prevalence are underestimated

Complete / Incomplete Hierarchical Hub Center Single Assignment Network Problem

In this paper we present the problem of designing a three level hub center network. In our network, the top level consists of a complete network where a direct link is between all central hubs.  The second and third levels consist of star networks that connect the hubs to central hubs and the demand nodes to hubs and thus to central hubs, respectively. We model this problem in an incomplete network environment. In this case, the top level is an incomplete network where the direct link between all central hubs is not necessary and may lead to lower transportation costs. We propose mixed integer programming model for these problems and conduct a computational study for these two developed models by using the CAB data

Spatial Analysis of Socio- Economic Inequalities Based on Multidimensional Welfare Indicators, Case study: Zahedan Urban Neighborhoods

Nowadays, cities are places for the economic development of societies, and as cities have human existence, they are one of the challenges of the fight against poverty to provide the proper infrastructure for economic growth and promotion. Focusing on enhancing multidimensional welfare indicators can minimize issues such as economic and social inequalities in the city. The aim of this study is spatial analysis of socio-economic inequalities of Zahedan based on multidimensional welfare indicators. In this study, multidimensional welfare indicators were measured in 55 dimensions in two dimensions of material welfare. In order to spatial analysis of multidimensional welfare indicators after normalization, welfare differences in urban neighborhoods were calculated and the results were prepared in the form of difference coefficient maps. Finally, the relation between the level of welfare and the coefficient of difference was evaluated using Pearson's statistical test. The results showed that the neighborhoods with the more welfare are located in district one and five in southwest of Zahedan and the north and south suburbs of Zahedan are in more undesirable condition than other urban areas. The results of correlation test between multidimensional welfare level and welfare difference coefficient also show that at alpha level of 0.1 there is only significant relationship between non-material welfare and housing components, access to services, infrastructures and facilities and knowledge with their difference coefficient. However, at Alpha level of 2 there is a significant relationship between material and immaterial welfare and housing components, access to services, health and knowledge with their difference coefficient

Relationship among dietary estimates of net endogenous acid production, bone mineral density and biochemical markers of bone turnover in an Iranian general population

Chronic, low-grade metabolic acidosis due toWestern diets may be a risk factor for osteoporosis. The severity can be determined in part by net endogenous acid production (NEAP). In a population-based study, a total of 1028 healthy men and women aged 20–72 years were evaluated for dietary intakes and NEAP estimates with a validated food frequency questionnaire. Dual-energy X-ray absorptiometry (DXA) was used to determine BMD of the lumbar spine (L2–L4), distal third of radius, and proximal femur. Serum CrossLaps, degradation products of the C-terminal telopeptides of type I collagen, and osteocalcin were measured by highly specific ELISA methods. Lower estimates of energy-adjusted rates of NEAP were associated with greater femoral neck BMD (p=0.01) in premenopausal women and with greater BMDs at the distal radius (p=0.001) and lumbar spine (p=0.04) in postmenopausal women. Compared with women in the highest quartile of the estimates of the energy-adjusted rates of NEAP, pre- and postmenopausal women in the lowest quartile had significantly greater means of osteocalcin [9.12 (SD±1.62) vs. 5.24 (SD±1.41) ng/ml, p=0.02 and 11.74 (SD±1.69) vs. 7.79 (SD±2.63) ng/ml, p=0.002, respectively]. Analysis by quartiles of the estimates of energy-adjusted rates of NEAP did not reveal a relationship between BMD and bone turnover markers in men. In conclusion, we found that a high energy-adjusted rate of NEAP was associated with a significantly lower BMD in women but not in men and the energy-adjusted rate of NEAP had a negative relationship with bone formation

Advanced Analysis of PRVEP in Anisometropic Amblyopia

Introduction: to identify the pattern-reversal visual evoked potential (PRVEP) waveform descriptor by evaluating discrete wavelet transform (DWT) in order to optimize stimulus in the diagnosis of anisometropia amblyopia. Materials and Methods: The PRVEP testing was performedfor 31 normal individuals and 35 patients with amblyopia. The stimuli were consisted of spatial frequencies of 1, 2, and 4 cycles per degree (cpd) and contrast levels of 100%, 50%, 25%, and 5%. The results were analyzed in the dimensions of time and time-frequency. DWT descriptor were extracted at level 7 (7P descriptor) for Haar, Daubechies 2, Daubechies 4, Symlet 5, Biorthogonal 3.5, Biorthogonal 4.4, and Coiflet 5 wavelets for 12 stimuli and compared between the two groups.  The correlation between different spatial frequencies at the same contrast level and the similarities between reconstructed signals and original waveforms were evaluated. Results: There were a significant reduction in P100 amplitude and a significant elevation in latency among the patient group. In the patients with amblyopia, 7P descriptor decreased in all analysis except for the frequency of 4 cpd and the contrast of 5% using bior4.4. No significant correlation was observed between different frequencies at a special contrast; however, there was a significant correlation between reconstructed signals and the original ones. Conclusion: The 7P descriptor could be used to distinguish between normal and abnormal signals in anisometropia amblyopia. Considering the results, DWT with coif5, db4, bior4.4, and bior3.5 wavelets can be utilized as a good indicator for selecting optimum stimulus

The Role of Perceived Risk in the Adoption of Internet of Things Technology in Sports

The Internet of Things (IoT) is one technology that can revolutionize traditional methods and transform sports infrastructure. To promote the adoption of IoT effectively, it's vital for sports manager to understand the factors that positively and negatively affect it. The aim of this study was to investigate how perceived risk impacts people's willingness to use IoT technology in sports. This quantitative study used a survey method and applied a descriptive approach. The statistical population included Iranian athletes, and 394 individuals completed questionnaires using a non-probability sampling method. Data analysis was performed using Smart PLS3 software. Results showed that perceived risk has a direct and negative impact on perceived ease of use, willingness to use, and perceived usefulness. However, its effect on attitude towards use was insignificant. The study also confirmed the positive impact of perceived ease of use on perceived usefulness and attitude towards use. Perceived usefulness had a greater effect on the latter variable. Additionally, perceived usefulness had a significant positive impact on willingness to use IoT technology in sports, as did attitude towards use. Attitude towards use also had a significant positive impact on willingness to use IoT technology in sports. The study recommends implementing strategies to enhance and improve perceived usefulness, ease of use, and attitude towards use while reducing perceived risk to increase acceptance and willingness to use IoT technology in sports

Detection QTLs for Grain Quality Traits and Yield in Two BILs Population of Rice

. Rice, the second most important crop after wheat, has been cultivated in Iran. Marketing conditions and quality traits after yield are the most important factors to adopt of new varieties. Therefore in recent years Iranian scientists decided to training on breeding improved high yield varieties with good grain quality.Quantitative trait loci (QTLs) yield and grain quality traits of rice (Oryza sativa L.) with additive, epistatic, and QTL × environment (QE) interaction effects were studied using a mixed-model-based composite interval mapping (MCIM) method and two populations of Back cross inbred lines (BILs) with a common maternal parent.In each of the populations two or three main effects of QTLs were detected for yield, amylose content, gel consistency and gelatinization temperature. Some identified QTL clusters suggested pleiotropic effects could control these traits. The phenotypic variation of AAE and AA QTLs effects were smaller than main QTLs. We conclude that the major genes and some minor and modifier genes controlled rice grain quality and yield components. The information obtained in this study have used to manipulating the QTLs for these traits by molecular marker-assisted selection and the best lines with excellent quality and high yield recognize

Clonidine Versus Chloral Hydrate for Recording Sleep EEG in Children

ObjectiveOne of the difficulties for conduct electroencephalography (EEG) in pediatric patient population is that they are not always cooperative during the procedure. Different medications have been used to induce sedation during EEG recording. In order to find a medication with least adverse effects and high efficacy, we aimed to compare clonidine and chloral hydrate as a premedication prior EEG performing in pediatric population. Materials & MethodsA prospective, randomized, single-blinded, controlled trial was carried out over 198 children (9 to 156 months) to investigate the sedative and adverse effects of clonidine and chloral hydrate. Patients, partially sleep-deprived the night before, were randomly divided in two groups of clonidine (100 patients) and chloral hydrate (98 patients), on an alternative day basis.Results The average sleep onset latency was significantly longer in the clonidine group than chloral hydrate group (Mann-Whitney test, p < 0.0001). Sleep duration ranged between 15-150 minutes and it was not significantly different between two groups (Mann-Whitney test p = 0.2). Drowsiness with chloral hydrate terminated faster than with clonidine. Drowsiness after arousal was seen in 58% and 26.1% of patients in the clonidine and chloral hydrate groups respectively that was  significant  (Mann-Whitney test, p = 0.058). EEG results were reported normal in 77 subjects in the chloral hydrate group (77%) and in 69 subjects (69%) in the clonidine group (p = 0.161). Generalized epileptiform discharges  reported significantly  in the clonidine group  (Mann-Whitney test , p = 0.006).ConclusionThe results of this study showed that both chloral hydrate 5% (one ml/kg)and clonidine (4 μg/kg)could be administered as a pre medication agent for EEG recording in children , although drowsiness after arousal of clonidine is greater than chloral hydrate . However, the yield of generalized epileptiform discharges in the clonidine group was more than the chloral hydrate group.

Effects of treatment of sleep disorders on sleep, psychological and cognitive functioning and biomarkers in individuals with HIV/AIDS and under methadone maintenance therapy

Poor sleep is a major complaint of people with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) and undergoing methadone maintenance therapy (MMT). We tested the impact of three different sleep-improving interventions (trazodone; sleep hygiene training; sleep hygiene training + trazodone) on sleep, psychological functioning and biomarkers in males with HIV and undergoing MMT.; A total of 75 male outpatients (mean age: 39.6 years) participated in a 12 week intervention. Participants were randomly assigned to one of the following conditions: trazodone 50 mg/d (TRAZ); sleep hygiene training (SHT); sleep hygiene training and trazodone (SHT + TRAZ). At baseline, and six and 12 weeks later, participants completed questionnaires covering subjective sleep and daytime sleepiness, and symptoms of depression and anxiety. In parallel, their cognitive performance (working memory; sustained attention) was assessed. Biomarkers (cortisol, BNDF, CD4; +; ) were assessed at baseline and at the end of the study.; Over time, sleep disturbances decreased and daytime functioning and overall sleep quality improved. More specifically, both sleep disturbances and daytime functioning improved in the two SHT conditions from baseline to week 6. Daytime functioning remained stable from week 6 to week 12. Over time, in all conditions symptoms of depression and anxiety declined from baseline to week 6 and remained lower from week 6 to week 12. Daytime sleepiness, symptoms of insomnia and sleep-disordered breathing remained unchanged. Sustained attention performance improved over time from baseline to week 6 and remained high through to week 12. Biomarkers remained unchanged.; In males with HIV and undergoing MMT, treating sleep disturbances over a period of six to 12 weeks had a positive impact on aspects of sleep disturbance, symptoms of depression and anxiety, and cognitive performance. The results indicate that sleep hygiene training, either as stand-alone or in combination with trazodone, can produce positive results