Mindfulness based interventions in multiple sclerosis: a systematic review

<b>Background</b> Multiple sclerosis (MS) is a stressful condition; depression, anxiety, pain and fatigue are all common problems. Mindfulness based interventions (MBIs) mitigate stress and prevent relapse in depression and are increasingly being used in healthcare. However, there are currently no systematic reviews of MBIs in people with MS. This review aims to evaluate the effectiveness of MBIs in people with MS.<p></p> <b>Methods</b> Systematic searches were carried out in seven major databases, using both subject headings and key words. Papers were screened, data extracted, quality appraised, and analysed by two reviewers independently, using predefined criteria. Study quality was assessed using the Cochrane Collaboration risk of bias tool. Perceived stress was the primary outcome. Secondary outcomes include mental health, physical health, quality of life, and health service utilisation. Statistical meta-analysis was not possible. Disagreements were adjudicated by a third party reviewer.<p></p> <b>Results</b> Three studies (n = 183 participants) were included in the final analysis. The studies were undertaken in Wales (n = 16, randomised controlled trial - (RCT)), Switzerland (n = 150, RCT), and the United States (n = 17, controlled trial). 146 (80%) participants were female; mean age (SD) was 48.6 (9.4) years. Relapsing remitting MS was the main diagnostic category (n = 123, 67%); 43 (26%) had secondary progressive disease; and the remainder were unspecified. MBIs lasted 6–8 weeks; attrition rates were variable (5-43%); all employed pre- post- measures; two had longer follow up; one at 3, and one at 6 months. Socio-economic status of participants was not made explicit; health service utilisation and costs were not reported. No study reported on perceived stress. All studies reported quality of life (QOL), mental health (anxiety and depression), physical (fatigue, standing balance, pain), and psychosocial measures. Statistically significant beneficial effects relating to QOL, mental health, and selected physical health measures were sustained at 3- and 6- month follow up.<p></p> <b>Conclusion</b> From the limited data available, MBIs may benefit some MS patients in terms of QOL, mental health, and some physical health measures. Further studies are needed to clarify how MBIs might best serve the MS population.<p></p&gt

Radial Velocity and Metallicity of the Globular Cluster IC4499 Obtained with AAOmega

We present radial velocity and metallicity measurements for the far-southern Galactic globular cluster IC4499. We selected several hundred target red giant stars in and around the cluster from the 2MASS point source catalog, and obtained spectra at the near-infrared calcium triplet using the AAOmega spectrograph. Observations of giants in globular clusters M4, M22, and M68 were taken to provide radial velocity and metallicity comparison objects. Based on velocity data we conclude that 43 of our targets are cluster members, by far the largest sample of IC4499 giants spectroscopically studied. We determine the mean heliocentric radial velocity of the cluster to be 31.5 plus or minus 0.4 km/s, and find the most likely central velocity dispersion to be 2.5 plus or minus 0.5 km/s. This leads to a dynamical mass estimate for the cluster of 93 plus or minus 37 thousand solar masses. We are sensitive to cluster rotation down to an amplitude of about 1 km/s, but no evidence for cluster rotation is seen. The cluster metallicity is found to be [Fe/H] = -1.52 plus or minus 0.12 on the Carretta-Gratton scale. The radial velocity of the cluster, previously highly uncertain, is consistent with membership in the Monoceros tidal stream, but also with a halo origin. The horizontal branch morphology of the cluster is slightly redder than average for its metallicity, but it is likely not unusually young compared to other clusters of the halo. The new constraints on the cluster kinematics and metallicity may give insight into its extremely high specific frequency of RR Lyrae stars.Comment: Accepted to MNRAS, 13 pages, 9 figure

Halo globular clusters observed with AAOmega: dark matter content, metallicity and tidal heating

Globular clusters have proven to be essential to our understanding of many important astrophysical phenomena. Here we analyse spectroscopic observations of ten Halo globular clusters to determine their dark matter content, their tidal heating by the Galactic disc and halo, describe their metallicities and the likelihood that Newtonian dynamics explain their kinematics. We analyse a large number of members in all clusters, allowing us to address all these issues together, and we have included NGC 288 and M30 to overlap with previous studies. We find that any flattening of the velocity dispersion profiles in the outer regions of our clusters can be explained by tidal heating. We also find that all our GCs have M/L_V < 5, therefore, we infer the observed dynamics do not require dark matter, or a modification of gravity. We suggest that the lack of tidal heating signatures in distant clusters indicates the Halo is not triaxial. The isothermal rotations of each cluster are measured, with M4 and NGC 288 exhibiting rotation at a level of 0.9 +/- 0.1 km/s and 0.25 +/- 0.15 km/s, respectively. We also indirectly measure the tidal radius of NGC 6752, determining a more realistic figure for this cluster than current literature values. Lastly, an unresolved and intriguing puzzle is uncovered with regard to the cooling of the outer regions of all ten clusters.Comment: 12 pages, 8 figures, 1 table. Accepted for publication in MNRAS

Metallicities and Radial Velocities of Five Open Clusters Including a New Candidate Member of the Monoceros Stream

Near infrared spectra of 133 red giant stars from ten Galactic open clusters and two Galactic globular clusters spanning 2.2 dex in metallicity and 11 Gyr in age are presented. We combine this sample with ten clusters from Cole and collaborators to investigate the Ca II triplet line strengths and their relation to cluster metallicity and position along the red giant branch. We show that characterizing the stellar surface gravity using Ks band photometry (relative to the horizontal branch) taken from the Two Micron All-Sky Survey allows for metallicity measurements at least as precise as those derived using V or I band data. This has the great advantage that uniform photometry and reliable astrometry is available for a large number of clusters. Using Ks band photometry also reduces the effect of differential reddening within a given cluster. We find no significant evidence for age or metallicity effects to the linear Ca II triplet - metallicity relationship over the small range in magnitudes studied when homogeneous reference metallicities are used. We derive the first spectroscopic metallicity and new radial velocity estimates for five open clusters: Berkeley 81, Berkeley 99, IC 1311, King 2, and NGC 7044. King 2 has an anomalous radial velocity compared with the local disk population. We discuss the possibility that it is part of the Monoceros tidal stream.Comment: 35 pages, 14 figures, 9 tables. Accepted for publication in MNRA

Blue Straggler Stars in Globular Clusters: a powerful tool to probe the internal dynamical evolution of stellar systems

This chapter presents an overview of the main observational results obtained to date about Blue Straggler Stars (BSSs) in Galactic Globular Clusters (GCs). The BSS specific frequency, radial distribution, chemical composition and rotational properties are presented and discussed in the framework of using this stellar population as probe of GC internal dynamics. In particular, the shape of the BSS radial distribution has been found to be a powerful tracer of the dynamical age of stellar systems, thus allowing the definition of the first empirical "dynamical clock".Comment: Chapter 5, in Ecology of Blue Straggler Stars, H.M.J. Boffin, G. Carraro & G. Beccari (Eds), Astrophysics and Space Science Library, Springe

The Century Survey Galactic Halo Project III: A Complete 4300 deg^2 Survey of Blue Horizontal Branch Stars in the Metal-Weak Thick Disk and Inner Halo

We present a complete spectroscopic survey of 2414 2MASS-selected blue horizontal branch (BHB) candidates selected over 4300 deg^2 of the sky. We identify 655 BHB stars in this non-kinematically selected sample. We calculate the luminosity function of field BHB stars and find evidence for very few hot BHB stars in the field. The BHB stars located at a distance from the Galactic plane |Z|<4 kpc trace what is clearly a metal-weak thick disk population, with a mean metallicity of [Fe/H]= -1.7, a rotation velocity gradient of dv_{rot}/d|Z|= -28+-3.4 km/s in the region |Z|<6 kpc, and a density scale height of h_Z= 1.26+-0.1 kpc. The BHB stars located at 5<|Z|<9 kpc are a predominantly inner-halo population, with a mean metallicity of [Fe/H]= -2.0 and a mean Galactic rotation of -4+-31 km/s. We infer the density of halo and thick disk BHB stars is 104+-37 kpc^-3 near the Sun, and the relative normalization of halo to thick-disk BHB stars is 4+-1% near the Sun.Comment: 12 pages in emulateapj format, accepted for publication in February A

A Randomised Experiment Evaluating the Mindful Raisin Practice as a Method of Reducing Chocolate Consumption During and After a Mindless Activity

The present study investigated the impact of the mindful raisin exercise on overeating during and after the experiment while controlling for wellbeing. One-hundred and twenty-eight participants were recruited and completed a questionnaire on wellbeing (i.e. depression, anxiety and stress) and state mindfulness. Participants were randomly allocated to either the mindful raisin exercise or a newspaper reading control condition. The State Mindfulness Scale was then completed again, and participants watched a neutral video while exposed to chocolate for 10 min. For those 10 min, results showed that the mindfulness condition translated into lower food consumption during the mindless activity when compared to the control condition. Post experiment, participants were asked to wait for 5 min, and any extra chocolate consumption during this time was recorded. Post-consumption was non-significantly different between the two groups, with those in the mindfulness condition consuming 1.3 g less than those in the control group. Controlling for wellbeing did not alter the impact of the mindfulness intervention on consumption. Implications for future work and practical applications for weight regulation are discussed