Continuous time delta sigma modulators with reduced clock jitter sensitivity

In this paper, a technique and method is presented to suppress the effect of clock-jitter in continuous-time delta-sigma modulators with switched-current (current-steering) digital to analogue converters. A behavioural, transistor-level and noise analysis are presented followed by circuit-level simulations. The proposed approach which is a switched-current type of digital to analogue conversion is fully compatible with CMOS processes and multi-bit operations which are widely used in high speed applications. Moreover, having a pulse-shaped output signal does not introduce extra demands on the modulator and hence does not increase the modulator's power consumption. A third-order continuous-time /spl Delta//spl Sigma/ modulator with the proposed digital-to-analogue converter in its feedback was used for circuit-level simulations. Results proved the robustness of the technique in suppressing the clock-jitter effects

A new structure for capacitor-mismatch-insensitive multiply-by-two amplification

A new approach to achieve a switched-capacitor multiply-by-two gain-stage with reduced sensitivity to capacitors' mismatches is presented in this paper. It is based on sampling fully differential input signals onto both plates of the input capacitors rather than sampling onto one plate of the capacitors with the other tied to a reference. It uses one operational amplifier (op-amp) in two phases to produce the gain of two (/spl times/2). Comparing to the conventional multiply-by-two gain-stage, the mismatches between the capacitors has a much smaller influence on the accuracy of the gain of two (/spl times/2). Analytical and circuit-level analysis of the architecture and the conventional structure are presented using a generic 0.35/spl mu/m CMOS technology

Modeling of switched-capacitor delta-sigma Modulators in SIMULINK

Precise behavioral modeling of switched-capacitor /spl Delta//spl Sigma/ modulators is presented. Considering noise (switches' and op-amps' thermal noise), clock jitter, nonidealities of integrators and op-amps including finite dc-gain (DCG) and unity gain bandwidth, slew-limiting, DCG nonlinearities and the input parasitic capacitance, quantizer hysteresis, switches' clock-feedthrough, and charge injection, exhaustive behavioral simulations that are close models of the transistor-level ones can be performed. The DCG nonlinearity of the integrators, which is not considered in many /spl Delta//spl Sigma/ modulators' modeling attempts, is analyzed, estimated, and modeled. It is shown that neglecting this parameter would lead to a significant underestimation of the modulators' behavior and increase the noise floor as well as the harmonic distortion at the output of the modulator. Evaluation and validation of the models were done via behavioral and transistor-level simulations for a second-order modulator using SIMULINK and HSPICE with a generic 0.35-/spl mu/m CMOS technology. The effects of the nonidealities and nonlinearities are clearly seen when compared to the ideal modulator in the behavioral and actual modulator in the circuit-level environment

Using sterile insect technique against Carob moth, Ectomyelois ceratoniae (Zeller) (Lep.: Pyralidae), in Yazd province, Iran

Carob moth, Ectomyelois ceratoniae (Zeller) (Lep.: Pyralidae), is the most important pest of pomegranate fruit in Iran where the cryptic activity of its larva makes the application of insecticides practically impossible. In this research, we evaluated the viability of the sterile insect technique against the carob moth in two isolated regions in Yazd province (Aqda and Mehriz). The mass rearing of the pest was performed in clean rooms on artificial diet under environmental conditions, 29±1 ºC and 75±5 %RH applying 165 Gy gamma ray as sterilizing doze. The sterile insects were released periodically in Aqda orchards (45 hectares) and in Chah Sheida (12 hectares) in Mehriz between March and November 2015. The infestation rate of carob moth in Aqda and Mehriz significantly reduced, in both target regions and control areas, by 12.27% and 44.02%, as well as 12.06% and 50.11%, for Aqda and Mehriz, respectively. It was concluded that periodical release of sterile carob moths can effectively lower the density of pest population and its economic loss on the harvest

The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019

Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden

High power factor wireless power transfer front-end circuit for heterogeneous systems

This paper investigates a high power factor switch-based wireless power transfer front-end circuit for heterogeneous systems. This circuit uses an integrated switching rectifier, implemented in 0.18um 1.8V/5V CMOS process. An integrated pair of phase synchronizers is used to align the waveshape of a wirelessly-coupled sinusoidal voltage source in the receiving coil to the corresponding conducting current. Using this approach, the power factor can be increased above 0.9 without requiring any wireless or wired feedback to the transmitter. The integrated switching rectifier can also provide: ac-dc rectification; facilitate the deployment of multi-receiver to single-transmitter wireless power transfer; and have the capability for voltage up and down conversion of the peak amplitude of the sinusoidal voltage source by use of a pulse-width modulation controller. From measured results, the output voltage can be stepped down from 1.65V to 1.08V and stepped up from 1.5V to 1.68V. Also, the measured power factor is 0.9 when the conducting current is managed at continuous conduction mode