89 research outputs found
The rate of using financial and non-financial indices in performance measurement of power distribution company in Markazi Province
According to conventional assessment indices of institutions or financial indices, balanced scorecard pays attention to non-financial indices which are mainly control and log indicators. In this direction, while having a close relationship between these two indices i.e. financial and non- financial indices, we are trying to verify organization objectives and strategies by applying all facilities and aptitudes of organization towards a main perspective. The function of different parts of organization is constantly evaluated by four perspectives of balanced scorecard including financial perspective, customer’s perspective, internal processes and developing and learning, and finally their development and improvement is tested
The rate of using financial and non-financial indices in performance measurement of power distribution company in Markazi Province
According to conventional assessment indices of institutions or financial indices, balanced scorecard pays attention to non-financial indices which are mainly control and log indicators. In this direction, while having a close relationship between these two indices i.e. financial and non- financial indices, we are trying to verify organization objectives and strategies by applying all facilities and aptitudes of organization towards a main perspective. The function of different parts of organization is constantly evaluated by four perspectives of balanced scorecard including financial perspective, customer’s perspective, internal processes and developing and learning, and finally their development and improvement is tested
The rate of using financial and non-financial indices in performance measurement of power distribution company in Markazi Province
According to conventional assessment indices of institutions or financial indices, balanced scorecard pays attention to non-financial indices which are mainly control and log indicators. In this direction, while having a close relationship between these two indices i.e. financial and non- financial indices, we are trying to verify organization objectives and strategies by applying all facilities and aptitudes of organization towards a main perspective. The function of different parts of organization is constantly evaluated by four perspectives of balanced scorecard including financial perspective, customer’s perspective, internal processes and developing and learning, and finally their development and improvement is tested
Effectiveness of spiritual group therapy on quality of life and spiritual well-being among patients with breast cancer
Cancer is deemed the century�s major health problem, and its increasing growth during the last decades has made experts concerned more than ever. Of all types of cancer, breast cancer is regarded as the second most common disease among women. The aim of this study was to determine the effectiveness of spiritual group therapy on quality of life and spiritual well-being among patients suffering from breast cancer. The present research was carried out between March and June 2011. The sample consisted of 24 participants randomly assigned to 2 groups: an experimental group (n, 12) and a control group (n,12). All the subjects completed questionnaires on quality of life and spiritual well-being in pretest and posttest. The experimental group received 12 sessions of spiritual group therapy. The results demonstrated improvement in quality of life and spiritual well-being in the experimental group. In conclusion, spiritual group therapy can be used to improve quality of life and spiritual well-being (religious health and existential health) among patients with breast cancer. © 2016, Shiraz University of Medical Sciences. All rights reserved
Effects of clomiphene citrate plus estradiol or progesterone on endometrial ultrastructure: An RCT
Background: Pinopods concentrations in endometrial surface is a marker of implantation. Estradiol valerate (EV) was used to change the adverse effects of Clomiphene Citrate (CC) on the endometrium.
Objective: The goal was to assess whether there is a significant difference in the endometrial pinopods concentrations and other parameters after adding EV and progesterone to higher doses of CC.
Materials and Methods: In this prospective randomized clinical trial, a total of 30 women who did not respond to 100 mg of CC from February 2016 to June 2016 were evaluated. They were divided into three groups: group I) received 150 mg of CC alone, group II) CC with EV, and group III) CC plus progesterone. On day 21 of the menstrual cycle, endometrial biopsy, a blood sampling, and a scanning by electron microscopy were performed.
Results: On day 21 of the menstrual cycle, there was no significant difference in the pinopods concentrations (p = 0.641) and serum estrogen levels (p = 0.276) between groups. However, the Serum progesterone levels in group I was higher than the other two groups (p = 0.007) in the same day.
Conclusion: Since the addition of EV and progesterone to higher dosages of CC did not change the pinopods concentration and serum estrogen levels on day 21 of the menstrual cycle, and the serum progesterone levels was higher in CC alone group (i.e. group I) compared to other groups, it can be concluded that the anti-estrogenic effects of CC just appear on the endometrium and not on the plasma levels.
Key words: Ovulation induction, Clomiphene, Estradiol, Progesterone, Electron microscopy, Endometrium
Multiple Congenital Anomalies in a Preterm Neonate with G6PD Deficiency from Consanguineous Parents
Introduction: Congenital anomalies can be defined as structural or functional disorders, including metabolic disorders. The prevalence of congenital anomalies is not high. Case Presentation: We would like to present a 34-week- preterm neonate with glucose-6-phosphate dehydrogenase deficiency who was born with several fetal anomalies from consanguineous parents. Mother had a twin-birth pregnancy which one of twins died because of lung hemorrhage and the second twin was born with multiple anomalies four fingers in both hands, short legs attached to the pelvic bone, and absence of tibia, fibula, and ankle bones. Hemimelia, which was mostly known as the congenital deformity and a type of phocomelia, is extremely rare. To detect most of these types of anomalies, magnetic resonance imaging, radiography, ultrasound, and computed tomography scan can be used. Conclusion: Congenital anomalies are the cause of many infants' deaths. To detect most of these types of anomalies, MRI, radiography, ultrasound, and computed tomography (CT) scan can be used
Effect of calcium promoter on nano structure iron catalyst for Fischer–Tropsch synthesis
The Fischer-Tropsch synthesis (FTS) has been recognized as a heterogeneous surface-catalyzed polymerization process. During this process, CHx monomers formed via the hydrogenation of adsorbed CO on transition metals produce hydrocarbons and oxygenates with a broad range of chain lengths and functional groups. A series of Fe/Cu Fischer-Tropsch synthesis catalysts incorporated with a calcium promoter were prepared by a microemulsion method. The composition of the final nanosized iron catalysts in terms of the atomic ratio is as follows: 100Fe/4Cu, 100Fe/4Cu/2Ca, 100Fe/4Cu/4Ca. XRD, BET, TEM, and TPR techniques were used to study the catalysts phase, structure, and morphology. Fischer-Tropsch synthesis (FTS) reaction test was performed in a fixed bed reactor. All the promoted catalysts, compared to the unpromoted catalysts, have higher rates of FT and the secondary reaction for CO2 production. The formation of methane and light hydrocarbons is restrained with increasing the amount of calcium. The 100Fe/4Cu/2Ca shows the best performance between the prepared catalysts.</span
Investigating the Factors Related to Desire to Have Children: A Systematic Review
Background and purpose: Reducing the desire to have children is one of the most important concerns and challenges in developed and developing countries. Also, the current policies in these countries try to understand the factors related to it, and until today, through this way, it has led to an increase in the population in countries with an aging population. Considering the importance of this issue, we decided to prepare and compile a study to determine the factors related to the desire to have children systematically.
Materials and methods: This study was conducted in 2024, which is a systematic review, and was conducted in five stages, which included designing the study question, searching, extracting related studies, selecting related studies, tabulating information, and reporting the results. Was. Searching in domestic and foreign databases including SID, PubMed, magician, Iran doc, Science Direct, Scopus, and Google Scholar search engine with keywords such as "related factors", "childbearing", "psychological factors", "social factors", Cultural factors, "physical factors", "individual factors", "religious factors", "decrease", "Iran" and "tendency" and their English equivalents were carried out. Studies were reviewed in the period from 2012 to 2024 (the last twelve years, due to major changes in the world). To select studies, inclusion or exclusion criteria were considered. Also, the quality screening of the studies was done by the Newcastle checklist. After selecting and checking the quality, the data in the studies were classified.
Results: Based on the answer to the main research question, the findings were classified into three categories: social and environmental factors, psycho-physical factors, and demographic factors. The review of 16 cross-sectional studies showed that factors such as sex, age, marriage, education, race, and place of residence are included in the demographic class. Among other relevant factors is the desire to have children. Religion and religion, technological progress, life experiences, culture and politics governing the society, family structure, peers and economic issues, and access to the media are among other related issues that are included in the category of social and environmental factors and are mentioned in 6 studies. became. The analysis of 7 other cross-sectional studies pointed to the connection of the next class, i.e. psycho-physical factors. In these studies, factors such as personality, depression, self-esteem, underlying disease, and fertility and infertility records were related to having children. It should be noted that some studies were placed in several classes and the classes overlapped.
Conclusion: Based on the findings of this study, it can be concluded that there are many factors related to people's desire to have children, which the studies in this research are not sufficient in expressing. But it is possible to take help from these factors that have been mentioned in various studies as a guide to know the related factors and by planning to manage or strengthen some of them, help to increase the desire to have children
Does the human placenta express the canonical cell entry mediators for SARSCoV-2?
The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected more than 10 million people, including pregnant women. To date, no consistent evidence for the vertical transmission of SARS-CoV-2 exists. The novel coronavirus canonically utilizes the angiotensin-converting enzyme 2 (ACE2) receptor and the serine protease TMPRSS2 for cell entry. Herein, building upon our previous single-cell study (Pique-Regi et al., 2019), another study, and new single-cell/nuclei RNA-sequencing data, we investigated the expression of ACE2 and TMPRSS2 throughout pregnancy in the placenta as well as in third-trimester chorioamniotic membranes. We report that co-transcription of ACE2 and TMPRSS2 is negligible in the placenta, thus not a likely path of vertical transmission for SARS-CoV-2. By contrast, receptors for Zika virus and cytomegalovirus, which cause congenital infections, are highly expressed by placental cell types. These data show that the placenta minimally expresses the canonical cell-entry mediators for SARS-CoV-2
Role of germ line p53 mutations in aneuploidy and immortalization of dermal fibroblasts from Li-Fraumeni cancer patients
Pedigree analysis of certain families with a high incidence of tumors suggests a genetic predisposition to cancer. Li and Fraumeni described a familial cancer syndrome that is characterized by multiple primary tumors, early age of onset, and marked variation in tumor type. Williams and Strong (1) demonstrated that at least 7% of childhood soft tissue sarcoma patients had family histories that is readily explained by a highly penetrant autosomal dominant gene. To characterize the mechanism for genetic predisposition to many tumor types in these families, we have studied genetic alterations in fibroblasts, a target tissue from patients with the Li-Fraumeni Syndrome (LFS). We have observed spontaneous changes in initially normal dermal fibroblasts from LFS patients as they are cultured in vitro. The cells acquire an altered morphology, chromosomal anomalies, and anchorage-independent growth. This aberrant behavior of fibroblasts from LFS patients had never been observed in fibroblasts from normal donors. In addition to these phenotypic alterations, patient fibroblasts spontaneously immortalize by 50 population doublings (pd) in culture; unlike controls that remain normal and senesce by 30-35 (2). At 50 pd, immortal fibroblasts from two patients were found to be susceptible to tumorigenic transformation by an activated T24 H-ras oncogene (3). Approximately 80% of the oncogene expressing transfectants were capable of forming tumors in nude mice within 2-3 weeks. p53 has been previously associated with immortalization of cells in culture and cooperation with ras in transfection assays. Therefore, patients\u27 fibroblast and lymphocyte derived DNA was tested for point mutations in p53. It was shown that LFS patients inherited certain point mutations in one of the two p53 alleles (4). Further studies on the above LFS immortal fibroblasts have demonstrated loss of the remaining p53 allele concomitant with escape from senescence. While the loss of the second allele correlates with immortalization it is not sufficient to transformation by an activated H-ras or N-ras oncogene. These immortal fibroblasts are resistant to tumorigenic transformation by v-abl, v-src, c-neu or v-mos oncogene; implying that additional steps are required in the tumorigenic progression of LFS patients\u27 fibroblasts. References. (1) Williams et al., J. Natl. Cancer Inst. 79:1213, 1987. (2) Bischoff et al., Cancer Res. 50:7979, 1990. (3) Bischoff et al., Oncogene 6:183, 1991. (4) Malkin et al., Science 250:1233, 1990
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